C18E1 (BioDeep_00000861967)
代谢物信息卡片
Poly(oxy-1,2-ethanediyl), .alpha.-octadecyl-.omega.-hydroxy-
化学式: C20H42O2 (314.3184632)
中文名称: 2-(十八氧基)乙醇
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCCCCCCCCCCCCCCCCOCCO
InChI: InChI=1S/C20H42O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-19-22-20-18-21/h21H,2-20H2,1H3
描述信息
D013501 - Surface-Active Agents > D011092 - Polyethylene Glycols
D001697 - Biomedical and Dental Materials
同义名列表
12 个代谢物同义名
Poly(oxy-1,2-ethanediyl), .alpha.-octadecyl-.omega.-hydroxy-; Ethylene glycol monooctadecyl ether; Rhodium(3+) tris(2-ethylhexanoate); Ethanol, 2-(octadecyloxy)-; 2-(Octadecyloxy)ethanol; 2-Octadecoxyethanol; 2-stearyloxyethanol; EINECS 218-374-0; Octadecylglycol; 03821_FLUKA; 2136-72-3; C18E1
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
2 个相关的物种来源信息
- 33090 - 白芷: -
- 33090 - 金银花: -
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Wei Xiong, Shi Hang Xiong, Qi Ling Chen, Ke Gang Linghu, Guan Ding Zhao, John M T Chu, Gordon T C Wong, Juan Li, Yuan Jia Hu, Yi Tao Wang, Hua Yu. Brij-functionalized chitosan nanocarrier system enhances the intestinal permeability of P-glycoprotein substrate-like drugs.
Carbohydrate polymers.
2021 Aug; 266(?):118112. doi:
10.1016/j.carbpol.2021.118112. [PMID: 34044929] - Laurence Ho, Mehrdad Bokharaei, Shyh-Dar Li. Current update of a thermosensitive liposomes composed of DPPC and Brij78.
Journal of drug targeting.
2018 Jun; 26(5-6):407-419. doi:
10.1080/1061186x.2017.1419361. [PMID: 29325469] - Chiara Botto, Nicolò Mauro, Erika Amore, Elisabetta Martorana, Gaetano Giammona, Maria Luisa Bondì. Surfactant effect on the physicochemical characteristics of cationic solid lipid nanoparticles.
International journal of pharmaceutics.
2017 Jan; 516(1-2):334-341. doi:
10.1016/j.ijpharm.2016.11.052. [PMID: 27889586] - Hongyu Ji, Jingling Tang, Mengting Li, Jinmei Ren, Nannan Zheng, Linhua Wu. Curcumin-loaded solid lipid nanoparticles with Brij78 and TPGS improved in vivo oral bioavailability and in situ intestinal absorption of curcumin.
Drug delivery.
2016; 23(2):459-70. doi:
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European journal of oral sciences.
2015 Jun; 123(3):179-85. doi:
10.1111/eos.12177. [PMID: 25782087] - Jonathan P May, Mark J Ernsting, Elijus Undzys, Shyh-Dar Li. Thermosensitive liposomes for the delivery of gemcitabine and oxaliplatin to tumors.
Molecular pharmaceutics.
2013 Dec; 10(12):4499-508. doi:
10.1021/mp400321e. [PMID: 24152292] - Jingling Tang, Yongjun Wang, Dun Wang, Yuhua Wang, Zhenghong Xu, Kelly Racette, Feng Liu. Key structure of brij for overcoming multidrug resistance in cancer.
Biomacromolecules.
2013 Feb; 14(2):424-30. doi:
10.1021/bm301661w. [PMID: 23311629] - Maria E N P Ribeiro, Carolina L de Moura, Mariano G S Vieira, Nilce V Gramosa, Chiraphon Chaibundit, Marcos C de Mattos, David Attwood, Stephen G Yeates, S Keith Nixon, Nágila M P S Ricardo. Solubilisation capacity of Brij surfactants.
International journal of pharmaceutics.
2012 Oct; 436(1-2):631-5. doi:
10.1016/j.ijpharm.2012.07.032. [PMID: 22842626] - Tatsuaki Tagami, Jonathan P May, Mark J Ernsting, Shyh-Dar Li. A thermosensitive liposome prepared with a Cu²⁺ gradient demonstrates improved pharmacokinetics, drug delivery and antitumor efficacy.
Journal of controlled release : official journal of the Controlled Release Society.
2012 Jul; 161(1):142-9. doi:
10.1016/j.jconrel.2012.03.023. [PMID: 22504351] - S Rahima Benhabbour, J Christopher Luft, Dongwook Kim, Anekant Jain, Saurabh Wadhwa, Matthew C Parrott, Rihe Liu, Joseph M DeSimone, Russell J Mumper. In vitro and in vivo assessment of targeting lipid-based nanoparticles to the epidermal growth factor-receptor (EGFR) using a novel Heptameric ZEGFR domain.
Journal of controlled release : official journal of the Controlled Release Society.
2012 Feb; 158(1):63-71. doi:
10.1016/j.jconrel.2011.10.013. [PMID: 22037106] - Tatsuaki Tagami, Mark J Ernsting, Shyh-Dar Li. Efficient tumor regression by a single and low dose treatment with a novel and enhanced formulation of thermosensitive liposomal doxorubicin.
Journal of controlled release : official journal of the Controlled Release Society.
2011 Jun; 152(2):303-9. doi:
10.1016/j.jconrel.2011.02.009. [PMID: 21338635] - Anekant Jain, Weili Yan, Keith R Miller, Ronan O'Carra, Jerold G Woodward, Russell J Mumper. Tresyl-based conjugation of protein antigen to lipid nanoparticles increases antigen immunogenicity.
International journal of pharmaceutics.
2010 Nov; 401(1-2):87-92. doi:
10.1016/j.ijpharm.2010.09.003. [PMID: 20837122] - J Q Zhang, J Liu, X L Li, B R Jasti. Preparation and characterization of solid lipid nanoparticles containing silibinin.
Drug delivery.
2007 Aug; 14(6):381-7. doi:
10.1080/10717540701203034. [PMID: 17701527] - Jigna D Patel, Ronan O'Carra, Julia Jones, Jerold G Woodward, Russell J Mumper. Preparation and characterization of nickel nanoparticles for binding to his-tag proteins and antigens.
Pharmaceutical research.
2007 Feb; 24(2):343-52. doi:
10.1007/s11095-006-9154-7. [PMID: 17180725] - X Dong, R J Mumper. The metabolism of fatty alcohols in lipid nanoparticles by alcohol dehydrogenase.
Drug development and industrial pharmacy.
2006 Sep; 32(8):973-80. doi:
10.1080/03639040600640006. [PMID: 16954110] - Anne Huhtala, Päivi Alajuuma, Susi Burgalassi, Patrizia Chetoni, Horst Diehl, Maria Engelke, Marios Marselos, Daniela Monti, Periklis Pappas, M Fabrizio Saettone, Lotta Salminen, Marianthi Sotiropoulou, Hanna Tähti, Hannu Uusitalo, Michaela Zorn-Kruppa. A collaborative evaluation of the cytotoxicity of two surfactants by using the human corneal epithelial cell line and the WST-1 test.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics.
2003 Feb; 19(1):11-21. doi:
10.1089/108076803762718079. [PMID: 12648300] - Zhengrong Cui, Russell J Mumper. Intranasal administration of plasmid DNA-coated nanoparticles results in enhanced immune responses.
The Journal of pharmacy and pharmacology.
2002 Sep; 54(9):1195-203. doi:
10.1211/002235702320402035. [PMID: 12356273] - S O Williams, S Long, J Allen, M L Wells. Scale-up of an oil/water cream containing 40\% diethylene glycol monoethyl ether.
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2000 Jan; 26(1):71-7. doi:
10.1081/ddc-100100329. [PMID: 10677812] - N Albertson, I Wenngren, J E Sjöström. Growth and survival of Helicobacter pylori in defined medium and susceptibility to Brij 78.
Journal of clinical microbiology.
1998 May; 36(5):1232-5. doi:
10.1128/jcm.36.5.1232-1235.1998. [PMID: 9574682] - J P Lens, P F Harmsen, E M ter Schegget, J G Terlingen, G H Engbers, J Feijen. Immobilization of functionalized alkyl-poly(ethylene oxide) surfactants on poly(ethylene) surfaces by means of an argon plasma treatment.
Journal of biomaterials science. Polymer edition.
1997; 8(12):963-82. doi:
10.1163/156856297x00128. [PMID: 9399145] - M Fukahori, S Akatsu, H Sato, T Yotsuyanagi. Effects of the structures of polyoxyethylene alkyl ethers on uptake of butyl p-hydroxybenzoate by Escherichia coli and its antibacterial activity.
Chemical & pharmaceutical bulletin.
1996 Dec; 44(12):2335-7. doi:
10.1248/cpb.44.2335. [PMID: 8996866] - P Bogner, D N Wheatley, C Borbély, A Miseta. Albumin can reverse the release of potassium from human erythrocytes treated with the non-ionic detergent, Brij 58.
Cell biology international.
1996 Nov; 20(11):741-9. doi:
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