methyl 5-[(3aS,5R,6R,6aS)-5-hydroxy-6-[(E,3R)-3-hydroxyoct-1-enyl]-1,3a,4,5,6,6a-hexahydropentalen-2-yl]pentanoate (BioDeep_00000859267)
代谢物信息卡片
化学式: C22H36O4 (364.2613)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCCCC(C=CC1C(CC2C1CC(=C2)CCCCC(=O)OC)O)O
InChI: InChI=1S/C22H36O4/c1-3-4-5-9-18(23)11-12-19-20-14-16(13-17(20)15-21(19)24)8-6-7-10-22(25)26-2/h11-13,17-21,23-24H,3-10,14-15H2,1-2H3/b12-11+/t17-,18+,19+,20-,21+/m0/s1
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
|---|
文献列表
- E Eber, T Uhlig, C McMenamin, P D Sly. Leflunomide, a novel immunomodulating agent, prevents the development of allergic sensitization in an animal model of allergic asthma.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.
1998 Mar; 28(3):376-84. doi:
10.1046/j.1365-2222.1998.00240.x. [PMID: 9543089] - T Minagawa, K Sakanaka, S Inaba, Y Sai, I Tamai, T Suwa, A Tsuji. Blood-brain-barrier transport of lipid microspheres containing clinprost, a prostaglandin I2 analogue.
The Journal of pharmacy and pharmacology.
1996 Oct; 48(10):1016-22. doi:
10.1111/j.2042-7158.1996.tb05893.x. [PMID: 8953502] - M Tanaka, C Kojima, M Muramatsu, H Tanabe. Binding affinities of isocarbacyclin methyl ester and its free acid to prostanoid receptors.
Arzneimittel-Forschung.
1995 Sep; 45(9):967-70. doi:
NULL. [PMID: 7488314] - K Sawada, K Aoki, Y Katsuura, H Tanabe, M Kiyoki, H Araki. Vasorelaxant effect of isocarbacyclin methyl ester incorporated into lipid microspheres on isolated canine arteries.
Arzneimittel-Forschung.
1995 Sep; 45(9):985-8. doi:
". [PMID: 7488318] - K Inoue, Y Aoki, S Kitahara, M Kiyoki, H Araki. Anti-platelet effects of isocarbacyclin methyl ester on human and rabbit platelets in vitro.
Arzneimittel-Forschung.
1995 Sep; 45(9):975-9. doi:
". [PMID: 7488316] - T Minagawa, Y Kohno, T Suwa, A Tsuji. Species differences in hydrolysis of isocarbacyclin methyl ester (TEI-9090) by blood esterases.
Biochemical pharmacology.
1995 May; 49(10):1361-5. doi:
10.1016/0006-2952(95)00071-7. [PMID: 7763277] - T Minagawa, Y Kohno, T Suwa, A Tsuji. Determination of protein binding of a highly lipophilic drug, isocarbacyclin methyl ester (TEI-9090), using a polydimethylsiloxane-coated glass beads assay.
The Journal of pharmacy and pharmacology.
1994 Oct; 46(10):838-43. doi:
10.1111/j.2042-7158.1994.tb03740.x. [PMID: 7699573] - K Hoshi, Y Mizushima. A preliminary double-blind cross-over trial of lipo-PGI2, a prostacyclin derivative incorporated in lipid microspheres, in cerebral infarction.
Prostaglandins.
1990 Aug; 40(2):155-64. doi:
10.1016/0090-6980(90)90081-6. [PMID: 2217831] - Y Mizushima, R Igarashi, K Hoshi, A K Sim, M E Cleland, H Hayashi, J Goto. Marked enhancement in antithrombotic activity of isocarbacyclin following its incorporation into lipid microspheres.
Prostaglandins.
1987 Feb; 33(2):161-8. doi:
10.1016/0090-6980(87)90003-7. [PMID: 3296005]
