Maropitant citrate (BioDeep_00000859116)

   


代谢物信息卡片


Maropitant citrate

化学式: C38H50N2O9 (678.351613)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(C)(C)C1=CC(=C(C=C1)OC)CNC2C3CCN(C2C(C4=CC=CC=C4)C5=CC=CC=C5)CC3.C(C(=O)O)C(CC(=O)O)(C(=O)O)O.O
InChI: /m0../s1

描述信息

D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents
C78272 - Agent Affecting Nervous System > C267 - Antiemetic Agent
D005765 - Gastrointestinal Agents > D000932 - Antiemetics
D002491 - Central Nervous System Agents

同义名列表

1 个代谢物同义名

Maropitant citrate



数据库引用编号

3 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • S R Karna, P Chambers, P Singh, N Lopez-Villalobos, K Kongara. Evaluation of analgesic interaction between morphine, maropitant and dexmedetomidine in dogs undergoing ovariohysterectomy. New Zealand veterinary journal. 2022 Jan; 70(1):10-21. doi: 10.1080/00480169.2021.1927231. [PMID: 33950785]
  • Sandeep Raj Karna, Paul Chambers, Craig B Johnson, Preet Singh, Lauren A Stewart, Nicolas Lopez-Villalobos, Kavitha Kongara. Effect of combinations of morphine, dexmedetomidine and maropitant on the electroencephalogram in response to acute electrical stimulation in anaesthetized dogs. Journal of veterinary pharmacology and therapeutics. 2020 Nov; 43(6):538-546. doi: 10.1111/jvp.12889. [PMID: 32614475]
  • Emily H Berryhill, Heather Knych, Munashe Chigerwe, Judy Edman, K Gary Magdesian. Pharmacokinetics of maropitant citrate after oral administration of multiple doses in adult horses. Journal of veterinary pharmacology and therapeutics. 2020 May; 43(3):282-287. doi: 10.1111/jvp.12844. [PMID: 32067245]
  • Sandeep Raj Karna, Preet Singh, Paul Chambers, Kavitha Kongara. Pharmacokinetics of morphine in combination with dexmedetomidine and maropitant following intramuscular injection in dogs anaesthetized with halothane. Journal of veterinary pharmacology and therapeutics. 2020 Mar; 43(2):153-161. doi: 10.1111/jvp.12831. [PMID: 31856324]
  • Sarah M Ozawa, Michelle G Hawkins, Tracy L Drazenovich, Philip H Kass, Heather K Knych. Pharmacokinetics of maropitant citrate in New Zealand White rabbits (Oryctolagus cuniculus). American journal of veterinary research. 2019 Oct; 80(10):963-968. doi: 10.2460/ajvr.80.10.963. [PMID: 31556710]
  • Emily H Berryhill, Heather Knych, Judy M Edman, K Gary Magdesian. Pharmacokinetics of single doses of maropitant citrate in adult horses. Journal of veterinary pharmacology and therapeutics. 2019 Jul; 42(4):487-491. doi: 10.1111/jvp.12768. [PMID: 31190332]
  • Jaclyn R Steinbach, Jamus MacGuire, Shu Chang, Elizabeth Dierks, Gordon S Roble. Assessment of pre-operative maropitant citrate use in macaque (Macaca fasicularis & Macaca mulatta) neurosurgical procedures. Journal of medical primatology. 2018 06; 47(3):178-184. doi: 10.1111/jmp.12343. [PMID: 29611200]
  • Atsushi Tsukamoto, Minami Ohgoda, Nozomi Haruki, Masatoshi Hori, Tomo Inomata. The anti-inflammatory action of maropitant in a mouse model of acute pancreatitis. The Journal of veterinary medical science. 2018 Mar; 80(3):492-498. doi: 10.1292/jvms.17-0483. [PMID: 29343664]
  • Hannah Kenward, Jonathan Elliott, Terry Lee, Ludovic Pelligand. Anti-nausea effects and pharmacokinetics of ondansetron, maropitant and metoclopramide in a low-dose cisplatin model of nausea and vomiting in the dog: a blinded crossover study. BMC veterinary research. 2017 Aug; 13(1):244. doi: 10.1186/s12917-017-1156-7. [PMID: 28814338]
  • Jessica M Quimby, William T Brock, Kelsey Moses, David Bolotin, Kayla Patricelli. Chronic use of maropitant for the management of vomiting and inappetence in cats with chronic kidney disease: a blinded, placebo-controlled clinical trial. Journal of feline medicine and surgery. 2015 Aug; 17(8):692-7. doi: 10.1177/1098612x14555441. [PMID: 25336450]
  • S P Lesman, J F Boucher, G S Grover, S R Cox, T L Bidgood. The pharmacokinetics of maropitant citrate dosed orally to dogs at 2 mg/kg and 8 mg/kg once daily for 14 days consecutive days. Journal of veterinary pharmacology and therapeutics. 2013 Oct; 36(5):462-70. doi: 10.1111/jvp.12027. [PMID: 23167698]
  • V de la Puente-Redondo, F D Tingley, R P Schneider, M A Hickman. The neurokinin-1 antagonist activity of maropitant, an antiemetic drug for dogs, in a gerbil model. Journal of veterinary pharmacology and therapeutics. 2007 Aug; 30(4):281-7. doi: 10.1111/j.1365-2885.2007.00847.x. [PMID: 17610400]
  • H A Benchaoui, S R Cox, R P Schneider, J F Boucher, R G Clemence. The pharmacokinetics of maropitant, a novel neurokinin type-1 receptor antagonist, in dogs. Journal of veterinary pharmacology and therapeutics. 2007 Aug; 30(4):336-44. doi: 10.1111/j.1365-2885.2007.00877.x. [PMID: 17610407]