Octenidine (BioDeep_00000859078)

   


代谢物信息卡片


Octenidine

化学式: C36H62N4 (550.4974212)
中文名称: 奥克太啶
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCCCCCCCN=C1C=CN(C=C1)CCCCCCCCCCN2C=CC(=NCCCCCCCC)C=C2
InChI: InChI=1S/C36H62N4/c1-3-5-7-9-15-19-27-37-35-23-31-39(32-24-35)29-21-17-13-11-12-14-18-22-30-40-33-25-36(26-34-40)38-28-20-16-10-8-6-4-2/h23-26,31-34H,3-22,27-30H2,1-2H3

描述信息

A - Alimentary tract and metabolism > A01 - Stomatological preparations > A01A - Stomatological preparations > A01AB - Antiinfectives and antiseptics for local oral treatment
R - Respiratory system > R02 - Throat preparations > R02A - Throat preparations > R02AA - Antiseptics
D000890 - Anti-Infective Agents
C254 - Anti-Infective Agent

同义名列表

1 个代谢物同义名

Octenidine



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Anas Abdullah Hamad. In vitro Evaluation the Efficacy of Some Nnew Plant Extracts and Biocides on the Viability of Acanthamoeba castellanii. Protist. 2023 May; 174(3):125966. doi: 10.1016/j.protis.2023.125966. [PMID: 37229821]
  • Kathrin Spettel, Dominik Bumberger, Iris Camp, Richard Kriz, Birgit Willinger. Efficacy of octenidine against emerging echinocandin-, azole- and multidrug-resistant Candida albicans and Candida glabrata. Journal of global antimicrobial resistance. 2022 06; 29(?):23-28. doi: 10.1016/j.jgar.2022.01.028. [PMID: 35134551]
  • Nermina Malanovic, Jessica A Buttress, Djenana Vejzovic, Ayse Ön, Paulina Piller, Dagmar Kolb, Karl Lohner, Henrik Strahl. Disruption of the Cytoplasmic Membrane Structure and Barrier Function Underlies the Potent Antiseptic Activity of Octenidine in Gram-Positive Bacteria. Applied and environmental microbiology. 2022 05; 88(10):e0018022. doi: 10.1128/aem.00180-22. [PMID: 35481757]
  • Ralf Smeets, Susanne Pfefferle, Henning Büttner, Johannes K Knobloch, Marc Lütgehetmann. Impact of Oral Rinsing with Octenidine Based Solution on SARS-CoV-2 Loads in Saliva of Infected Patients an Exploratory Study. International journal of environmental research and public health. 2022 05; 19(9):. doi: 10.3390/ijerph19095582. [PMID: 35564977]
  • Lucy J Bock, Philip M Ferguson, Maria Clarke, Vichayanee Pumpitakkul, Matthew E Wand, Paul-Enguerrand Fady, Leanne Allison, Roland A Fleck, Matthew J Shepherd, A James Mason, J Mark Sutton. Pseudomonas aeruginosa adapts to octenidine via a combination of efflux and membrane remodelling. Communications biology. 2021 09; 4(1):1058. doi: 10.1038/s42003-021-02566-4. [PMID: 34504285]
  • Mateusz Rzycki, Dominik Drabik, Kamila Szostak-Paluch, Beata Hanus-Lorenz, Sebastian Kraszewski. Unraveling the mechanism of octenidine and chlorhexidine on membranes: Does electrostatics matter?. Biophysical journal. 2021 08; 120(16):3392-3408. doi: 10.1016/j.bpj.2021.06.027. [PMID: 34214528]
  • Maria Loose, Kurt G Naber, Larry Purcell, Manfred P Wirth, Florian M E Wagenlehner. Anti-Biofilm Effect of Octenidine and Polyhexanide on Uropathogenic Biofilm-Producing Bacteria. Urologia internationalis. 2021; 105(3-4):278-284. doi: 10.1159/000512370. [PMID: 33401282]
  • Nermina Malanovic, Ayse Ön, Georg Pabst, Alfred Zellner, Karl Lohner. Octenidine: Novel insights into the detailed killing mechanism of Gram-negative bacteria at a cellular and molecular level. International journal of antimicrobial agents. 2020 Nov; 56(5):106146. doi: 10.1016/j.ijantimicag.2020.106146. [PMID: 32853670]
  • Benjamin M Clanner-Engelshofen, Lars E French, Markus Reinholz. Octenidine disinfection during the SARS-CoV-2 pandemia. European journal of dermatology : EJD. 2020 Oct; 30(5):613-614. doi: 10.1684/ejd.2020.3856. [PMID: 32972908]
  • Luka Grgar. Prevention of catheter-related urinary tract infections: The octenidine hypothesis. Medical hypotheses. 2020 Apr; 137(?):109561. doi: 10.1016/j.mehy.2020.109561. [PMID: 31952021]
  • M Besser, M Dietrich, L Weber, J D Rembe, E K Stuermer. Efficacy of antiseptics in a novel 3-dimensional human plasma biofilm model (hpBIOM). Scientific reports. 2020 03; 10(1):4792. doi: 10.1038/s41598-020-61728-2. [PMID: 32179838]
  • Paweł Kwiatkowski, Łukasz Łopusiewicz, Mateusz Kostek, Emilia Drozłowska, Agata Pruss, Bartosz Wojciuk, Monika Sienkiewicz, Hanna Zielińska-Bliźniewska, Barbara Dołęgowska. The Antibacterial Activity of Lavender Essential Oil Alone and In Combination with Octenidine Dihydrochloride against MRSA Strains. Molecules (Basel, Switzerland). 2019 Dec; 25(1):. doi: 10.3390/molecules25010095. [PMID: 31888005]
  • Kamila Szostak, Aleksander Czogalla, Magdalena Przybyło, Marek Langner. New lipid formulation of octenidine dihydrochloride. Journal of liposome research. 2018 Jun; 28(2):106-111. doi: 10.1080/08982104.2016.1275678. [PMID: 28006995]
  • Marie Kodedová, Hana Sychrová. Synthetic antimicrobial peptides of the halictines family disturb the membrane integrity of Candida cells. Biochimica et biophysica acta. Biomembranes. 2017 Oct; 1859(10):1851-1858. doi: 10.1016/j.bbamem.2017.06.005. [PMID: 28600071]
  • N Kapalschinski, H M Seipp, M Kückelhaus, K K Harati, J J Kolbenschlag, A Daigeler, F Jacobsen, M Lehnhardt, T Hirsch. Albumin reduces the antibacterial efficacy of wound antiseptics against Staphylococcus aureus. Journal of wound care. 2017 Apr; 26(4):184-187. doi: 10.12968/jowc.2017.26.4.184. [PMID: 28379100]
  • Tatiana V Ivanova, Grit Baier, Katharina Landfester, Eduard Musin, Sameer A Al-Bataineh, David C Cameron, Tomáš Homola, Jason D Whittle, Mika Sillanpää. Attachment of Poly(l-lactide) Nanoparticles to Plasma-Treated Non-Woven Polymer Fabrics Using Inkjet Printing. Macromolecular bioscience. 2015 Sep; 15(9):1274-82. doi: 10.1002/mabi.201500067. [PMID: 26013285]
  • C Ulrich, F Kluschke, A Patzelt, S Vandersee, V A Czaika, H Richter, A Bob, J von Hutten, C Painsi, R Hüge, A Kramer, O Assadian, J Lademann, B Lange-Asschenfeldt. Clinical use of cold atmospheric pressure argon plasma in chronic leg ulcers: A pilot study. Journal of wound care. 2015 May; 24(5):196, 198-200, 202. doi: 10.12968/jowc.2015.24.5.196. [PMID: 25970756]
  • Helen Levers. Switching to an antimicrobial solution for skin cleansing before urinary catheterisation. British journal of community nursing. 2014 Feb; 19(2):66, 68-71. doi: 10.12968/bjcn.2014.19.2.66. [PMID: 24514106]
  • Roland Schmitt, Hermann Haller, Marcus Hiss. Quiz page september 2012: erythematous rash around peritoneal dialysis catheter exit site. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2012 Sep; 60(3):A29-31. doi: 10.1053/j.ajkd.2012.04.030. [PMID: 22901637]
  • Sangeetha Ananda Baskaran, Abhinav Upadhyay, Indu Upadhyaya, Varunkumar Bhattaram, Kumar Venkitanarayanan. Efficacy of octenidine hydrochloride for reducing Escherichia coli O157:H7, Salmonella spp., and Listeria monocytogenes on cattle hides. Applied and environmental microbiology. 2012 Jun; 78(12):4538-41. doi: 10.1128/aem.00259-12. [PMID: 22467506]
  • J Lademann, H Richter, S Schanzer, A Patzelt, G Thiede, A Kramer, K-D Weltmann, B Hartmann, B Lange-Asschenfeldt. Comparison of the antiseptic efficacy of tissue-tolerable plasma and an octenidine hydrochloride-based wound antiseptic on human skin. Skin pharmacology and physiology. 2012; 25(2):100-6. doi: 10.1159/000335558. [PMID: 22301799]
  • Frédéric D Birkhäuser, Pascal Zehnder, Beat Roth, Leander Schürch, Katharina Ochsner, Rita Willener, George N Thalmann, Fiona C Burkhard, Urs E Studer. Irrigation of continent catheterizable ileal pouches: tap water can replace sterile solutions because it is safe, easy, and economical. European urology. 2011 Apr; 59(4):518-23. doi: 10.1016/j.eururo.2011.01.003. [PMID: 21256669]
  • F D Matl, J Zlotnyk, A Obermeier, W Friess, S Vogt, H Büchner, H Schnabelrauch, A Stemberger, K-D Kühn. New anti-infective coatings of surgical sutures based on a combination of antiseptics and fatty acids. Journal of biomaterials science. Polymer edition. 2009; 20(10):1439-49. doi: 10.1163/092050609x12457418973107. [PMID: 19622281]
  • Karl-Heinz Wagner, Alice Jürss, Beate Zarembach, Ibrahim Elmadfa. Impact of antiseptics on radical metabolism, antioxidant status and genotoxic stress in blood cells: povidone-iodine versus octenidine dihydrochloride. Toxicology in vitro : an international journal published in association with BIBRA. 2004 Aug; 18(4):411-8. doi: 10.1016/j.tiv.2003.12.001. [PMID: 15130597]
  • S Shapiro, E Giertsen, B Guggenheim. An in vitro oral biofilm model for comparing the efficacy of antimicrobial mouthrinses. Caries research. 2002 Mar; 36(2):93-100. doi: 10.1159/000057866. [PMID: 12037365]
  • D Michel, G A Zäch. Antiseptic efficacy of disinfecting solutions in suspension test in vitro against methicillin-resistant Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli in pressure sore wounds after spinal cord injury. Dermatology (Basel, Switzerland). 1997; 195 Suppl 2(?):36-41. doi: 10.1159/000246028. [PMID: 9403253]
  • M A Ghannoum, N M Moussa, P Whittaker, I Swairjo, K H Abu-Elteen. Subinhibitory concentration of octenidine and pirtenidine: influence on the lipid and sterol contents of Candida albicans. Chemotherapy. 1992; 38(1):46-56. doi: 10.1159/000238941. [PMID: 1618003]