Etalocib (BioDeep_00000859067)
代谢物信息卡片
化学式: C33H33FO6 (544.226105)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCC1=C(C=CC=C1OC2=CC=CC=C2C(=O)O)OCCCOC3=CC(=C(C=C3CC)C4=CC=C(C=C4)F)O
InChI: InChI=1S/C33H33FO6/c1-3-9-25-29(12-7-13-30(25)40-31-11-6-5-10-26(31)33(36)37)38-18-8-19-39-32-21-28(35)27(20-22(32)4-2)23-14-16-24(34)17-15-23/h5-7,10-17,20-21,35H,3-4,8-9,18-19H2,1-2H3,(H,36,37)
数据库引用编号
7 个数据库交叉引用编号
- ChEBI: CHEBI:187612
- KEGGdrug: D04074
- PubChem: 177941
- DrugBank: DB12850
- ChEMBL: CHEMBL329123
- CAS: 152608-41-8
- CAS: 161172-51-6
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Bartomeu Colom, Jennifer V Bodkin, Martina Beyrau, Abigail Woodfin, Christiane Ody, Claire Rourke, Triantafyllos Chavakis, Karim Brohi, Beat A Imhof, Sussan Nourshargh. Leukotriene B4-Neutrophil Elastase Axis Drives Neutrophil Reverse Transendothelial Cell Migration In Vivo.
Immunity.
2015 Jun; 42(6):1075-86. doi:
10.1016/j.immuni.2015.05.010
. [PMID: 26047922] - Xiaoyu Liu, Tingting Yang, Langxi Miao, Yan-Ai Mei, Changlong Hu. Leukotriene B4 Inhibits L-Type Calcium Channels via p38 Signaling Pathway in Vascular Smooth Muscle Cells.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology.
2015; 37(5):1903-13. doi:
10.1159/000438551
. [PMID: 26584289] - W Zhang, T McQueen, W Schober, G Rassidakis, M Andreeff, M Konopleva. Leukotriene B4 receptor inhibitor LY293111 induces cell cycle arrest and apoptosis in human anaplastic large-cell lymphoma cells via JNK phosphorylation.
Leukemia.
2005 Nov; 19(11):1977-84. doi:
10.1038/sj.leu.2403929
. [PMID: 16151469] - Gary K Schwartz, Aaron Weitzman, Eileen O'Reilly, Les Brail, Dinesh P de Alwis, Ann Cleverly, Barbara Barile-Thiem, Vincent Vinciguerra, Daniel R Budman. Phase I and pharmacokinetic study of LY293111, an orally bioavailable LTB4 receptor antagonist, in patients with advanced solid tumors.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2005 Aug; 23(23):5365-73. doi:
10.1200/jco.2005.02.766
. [PMID: 15939925] - Sabine G Plötz, Claudia Traidl-Hoffmann, Ivo Feussner, Anna Kasche, Alexandra Feser, Johannes Ring, Thilo Jakob, Heidrun Behrendt. Chemotaxis and activation of human peripheral blood eosinophils induced by pollen-associated lipid mediators.
The Journal of allergy and clinical immunology.
2004 Jun; 113(6):1152-60. doi:
10.1016/j.jaci.2004.03.011
. [PMID: 15208598] - E J Perkins, J W Cramer, N A Farid, M G Gadberry, D A Jackson, E L Mattiuz, D D O'Bannon, H J Weiss, W J Wheeler, P G Wood, K C Cassidy. Preclinical characterization of 2-[3-[3-[(5-ethyl-4'-fluoro-2-hydroxy[1,1'-biphenyl]-4-yl)oxy]propoxy]-2-propylphenoxy]benzoic acid metabolism: in vitro species comparison and in vivo disposition in rats.
Drug metabolism and disposition: the biological fate of chemicals.
2003 Nov; 31(11):1382-90. doi:
10.1124/dmd.31.11.1382
. [PMID: 14570771] - K Kuwabara, H Jyoyama, J H Fleisch, Y Hori. Inhibition of antigen-induced arthritis in guinea pigs by a selective LTB4 receptor antagonist LY293111Na.
Inflammation research : official journal of the European Histamine Research Society ... [et al.].
2002 Nov; 51(11):541-50. doi:
10.1007/pl00012425
. [PMID: 12540018] - B A Seegers, M P Andriessen, C A van Hooijdonk, E S de Bakker, I M van Vlijmen-Willems, G L Parker, P E van Erp, P C van de Kerkhof. Pharmacological effects of a specific leukotriene B(4) receptor antagonist (VML 295) on blood leukocytes, cutaneous inflammation and epidermal proliferation.
Skin pharmacology and applied skin physiology.
2000 Mar; 13(2):75-85. doi:
10.1159/000029911
. [PMID: 10754455] - W T Jackson, L L Froelich, R J Boyd, J P Schrementi, D L Saussy, R M Schultz, J S Sawyer, M J Sofia, D K Herron, T Goodson, D W Snyder, P A Pechous, S M Spaethe, C R Roman, J H Fleisch. Pharmacologic actions of the second-generation leukotriene B4 receptor antagonist LY293111: in vitro studies.
The Journal of pharmacology and experimental therapeutics.
1999 Jan; 288(1):286-94. doi:
NULL
. [PMID: 9862783]