1-Benzyl-2,3-dimethylguanidinium sulphate (2:1) (BioDeep_00000859041)
代谢物信息卡片
化学式: C20H32N6O4S (452.2205632)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C[NH2+]C(=NC)NCC1=CC=CC=C1.C[NH2+]C(=NC)NCC1=CC=CC=C1.[O-]S(=O)(=O)[O-]
InChI: (H2,1,2,3,4)
描述信息
C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C72900 - Adrenergic Antagonist
D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents > D013565 - Sympatholytics
C78274 - Agent Affecting Cardiovascular System > C270 - Antihypertensive Agent
D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents
D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents
同义名列表
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Sundaram V Ramanan. The aggressive treatment of hypertension.
Lancet (London, England).
2003 May; 361(9368):1510. doi:
10.1016/s0140-6736(03)13176-5. [PMID: 12737860] - S G Parker, P Raval, S Yeulet, R J Eden. Tolerance to peripheral, but not central, effects of ropinirole, a selective dopamine D2-like receptor agonist.
European journal of pharmacology.
1994 Nov; 265(1-2):17-26. doi:
10.1016/0014-2999(94)90218-6. [PMID: 7883025] - J L Anderson, M Anastasiou-Nana, V D Dayton, R N Creagar, R L Jensen, G J Wright. Myocardial bethanidine kinetics after single-dose intravenous infusion: correlation with plasma kinetics in closed-chest dogs.
Journal of cardiovascular pharmacology.
1985 May; 7(3):609-12. doi:
10.1097/00005344-198505000-00030. [PMID: 2410697] - D J Webb, A M Cumming, F C Adams, G P Hodsman, B J Leckie, A F Lever, J J Morton, G D Murray, J I Robertson. Changes in active and inactive renin and in angiotensin II across the kidney in essential hypertension and renal artery stenosis.
Journal of hypertension.
1984 Dec; 2(6):605-14. doi:
10.1097/00004872-198412000-00005. [PMID: 6396332] - J P DiMarco, T D Sellers, J R Shipe, J Savory, D H Spyker. Acute electrophysiologic effects of bethanidine sulfate in patients with ventricular tachycardia or fibrillation.
American heart journal.
1984 Nov; 108(5):1244-9. doi:
10.1016/0002-8703(84)90748-8. [PMID: 6496282] - J R Shipe, A F Arlinghaus, J Savory, M R Wills, J P DiMarco. Determination of bethanidine in plasma by liquid-chromatography with a microbore reversed-phase column.
Clinical chemistry.
1983 Oct; 29(10):1793-5. doi:
NULL. [PMID: 6616825] - D L Davies, K McElroy, A B Atkinson, J J Brown, A M Cumming, R Fraser, B J Leckie, A F Lever, A Mackay, J J Morton, J I Robertson. Relationship between exchangeable sodium and blood pressure in different forms of hypertension in man.
Clinical science (London, England : 1979).
1979 Dec; 57 Suppl 5(?):69s-75s. doi:
10.1042/cs057069s. [PMID: 396093] - C N Corder. Bethanidine elimination from plasma.
Journal of clinical pharmacology.
1979 Aug; 19(8-9 Pt 1):428-34. doi:
10.1002/j.1552-4604.1979.tb02504.x. [PMID: 489762] - T Oishi. Possible role of brain norepinephrine in the hypothalamic hypophyseal adrenal system.
Endocrinologia japonica.
1979 Jun; 26(3):399-409. doi:
10.1507/endocrj1954.26.399. [PMID: 477627] - Z H Israili. Correlation of pharmacological effects with plasma levels of antihypertensive drugs in man.
Annual review of pharmacology and toxicology.
1979; 19(?):25-52. doi:
10.1146/annurev.pa.19.040179.000325. [PMID: 36827] - C N Corder. Bethanidine dose, plasma levels, and antihypertensive effects.
Journal of clinical pharmacology.
1978 May; 18(5-6):249-58. doi:
10.1002/j.1552-4604.1978.tb02443.x. [PMID: 641213] - P G Hiley, Y S Pan, D Robertshaw, J E Vercoe. Effect of lipid solvents on cutaneous moisture loss.
Australian journal of biological sciences.
1977 Jun; 30(3):197-201. doi:
10.1071/bi9770197. [PMID: 921632] - J Steiner, J Cassar, K Mashiter, I Dawes, T R Fraser, A Breckenridge. Effects of methyldopa on prolactin and growth hormone.
British medical journal.
1976 May; 1(6019):1186-8. doi:
10.1136/bmj.1.6019.1186. [PMID: 1268617] - A N Chremos, D Shen, M Gibaldi, J D Proctor, J H Newman. Time-dependent change in renal clearance of bethanidine in humans.
Journal of pharmaceutical sciences.
1976 Jan; 65(1):140-2. doi:
10.1002/jps.2600650136. [PMID: 1255421] - C N Corder, T S Klaniecki, R H McDonald, C Berlin. Fluorometric assay of bethanidine in plasma.
Journal of pharmaceutical sciences.
1975 May; 64(5):785-92. doi:
10.1002/jps.2600640511. [PMID: 239198] - A E DOYLE, A MORLEY. STUDIES ON THE ABSORPTION AND EXCRETION OF (14C)-BETHANIDINE IN MAN.
British journal of pharmacology and chemotherapy.
1965 Jun; 24(?):701-4. doi:
10.1111/j.1476-5381.1965.tb01625.x. [PMID: 14340923]