Imexon (BioDeep_00000859037)
代谢物信息卡片
化学式: C4H5N3O (111.04326000000002)
中文名称: 亚美克松
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1C2N1C(=O)N=C2N
InChI: InChI=1S/C4H5N3O/c5-3-2-1-7(2)4(8)6-3/h2H,1H2,(H2,5,6,8)
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Thomas M Moehler, Reinhard Feneberg, Anthony Dick Ho, Anatoly K Golenkov, Heinz Ludwig, Martin Kropff, Nuriet K Khuageva, Jacek Hajda, Ingo von Broen, Hartmut Goldschmidt. Combined phase I/II study of imexon (AOP99.0001) for treatment of relapsed or refractory multiple myeloma.
Anti-cancer drugs.
2010 Aug; 21(7):708-15. doi:
10.1097/cad.0b013e32833b975b
. [PMID: 20571355] - Tomislav Dragovich, Michael Gordon, David Mendelson, Lucas Wong, Manuel Modiano, H-H Sherry Chow, Betty Samulitis, Steven O'Day, Kathryn Grenier, Evan Hersh, Robert Dorr. Phase I trial of imexon in patients with advanced malignancy.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2007 May; 25(13):1779-84. doi:
10.1200/jco.2006.08.9672
. [PMID: 17470869] - Alan Pourpak, Ross O Meyers, Betty K Samulitis, H-H Sherry Chow, Carole Y Kepler, Mary A Raymond, Evan Hersh, Robert T Dorr. Preclinical antitumor activity, pharmacokinetics and pharmacodynamics of imexon in mice.
Anti-cancer drugs.
2006 Nov; 17(10):1179-84. doi:
10.1097/01.cad.0000236305.43209.f0
. [PMID: 17075317] - R T Dorr, J D Liddil, M K Klein, E M Hersh. Preclinical pharmacokinetics and antitumor activity of imexon.
Investigational new drugs.
1995; 13(2):113-6. doi:
10.1007/bf00872858
. [PMID: 8617572] - R W Sidwell, J D Morrey, K M Okleberry, R A Burger, R P Warren. Immunomodulator effects on the Friend virus infection in genetically defined mice.
Annals of the New York Academy of Sciences.
1993 Jun; 685(?):432-46. doi:
10.1111/j.1749-6632.1993.tb35904.x
. [PMID: 8363251] - E M Hersh, T M Grogan, C Y Funk, C W Taylor. Suppression of human lymphoma development in the severe combined immune-deficient mouse by imexon therapy.
Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy.
1993 Feb; 13(2):77-83. doi:
10.1097/00002371-199302000-00001
. [PMID: 8391308] - J D Morrey, R P Warren, K M Okleberry, R A Burger, M A Chirigos, R W Sidwell. Effect of imexon treatment on Friend virus complex infection using genetically defined mice as a model for HIV-1 infection.
Antiviral research.
1991 Jan; 15(1):51-65. doi:
10.1016/0166-3542(91)90040-x
. [PMID: 2036000] - M A Chirigos, M A Ussery, P L Black. Imexon and biological response modifiers in murine models of AIDS.
International journal of immunopharmacology.
1991; 13 Suppl 1(?):33-41. doi:
10.1016/0192-0561(91)90122-n
. [PMID: 1823906]