N-Butanoyl-L-homoserine lactone (BioDeep_00000859027)
代谢物信息卡片
N-[(3s)-2-Oxotetrahydrofuran-3-Yl]butanamide
化学式: C8H13NO3 (171.0895)
中文名称: N-丁酰-L-高丝氨酸内酯, N-[（3s）-2-氧代四氢呋喃-3-基]丁酰胺
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCC(=O)NC1CCOC1=O
InChI: InChI=1S/C8H13NO3/c1-2-3-7(10)9-6-4-5-12-8(6)11/h6H,2-5H2,1H3,(H,9,10)/t6-/m0/s1
数据库引用编号
5 个数据库交叉引用编号
- ChEBI: CHEBI:177513
- KEGGdrug: D82565
- PubChem: 10130163
- ChEMBL: CHEMBL207316
- CAS: 67605-85-0
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
- 158786 - Lyngbya majuscula: 10.1016/S0031-9422(00)89364-4
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Huan Gao, Runyu Zhao, Zeyu Wu, Jinyu Ye, Lijie Duan, Ran Yu. New insights into exogenous N-acyl-homoserine lactone manipulation in biological nitrogen removal system against ZnO nanoparticle shock.
Bioresource technology.
2023 Feb; 370(?):128567. doi:
10.1016/j.biortech.2022.128567. [PMID: 36596365] - Du-Hwan Ryu, Sang-Won Lee, Viktorija Mikolaityte, Yea-Won Kim, Hae Young Jeong, Sang Jun Lee, Chung-Hak Lee, Jung-Kee Lee. Identification of a Second Type of AHL-lactonase from Rhodococcus sp. BH4, belonging to the α/β Hydrolase Superfamily.
Journal of microbiology and biotechnology.
2020 Jun; 30(6):937-945. doi:
10.4014/jmb.2001.01006. [PMID: 32160697] - Giordano Rampioni, Francesca D'Angelo, Marco Messina, Alessandro Zennaro, Yutetsu Kuruma, Daniela Tofani, Livia Leoni, Pasquale Stano. Synthetic cells produce a quorum sensing chemical signal perceived by Pseudomonas aeruginosa.
Chemical communications (Cambridge, England).
2018 Feb; 54(17):2090-2093. doi:
10.1039/c7cc09678j. [PMID: 29334092] - Shiyu Tao, Yanwen Luo, Bin He, Jie Liu, Xi Qian, Yingdong Ni, Ruqian Zhao. Paraoxonase 2 modulates a proapoptotic function in LS174T cells in response to quorum sensing molecule N-(3-oxododecanoyl)-L-homoserine lactone.
Scientific reports.
2016 07; 6(?):28778. doi:
10.1038/srep28778. [PMID: 27364593] - Andrés Corral-Lugo, Abdelali Daddaoua, Alvaro Ortega, Manuel Espinosa-Urgel, Tino Krell. Rosmarinic acid is a homoserine lactone mimic produced by plants that activates a bacterial quorum-sensing regulator.
Science signaling.
2016 Jan; 9(409):ra1. doi:
10.1126/scisignal.aaa8271. [PMID: 26732761] - Yangcheng Ding, Huajun Feng, Wenkun Huang, Dongsheng Shen, Meizhen Wang. A sustainable method for effective regulation of anaerobic granular sludge: artificially increasing the concentration of signal molecules by cultivating a secreting strain.
Bioresource technology.
2015 Nov; 196(?):273-8. doi:
10.1016/j.biortech.2015.07.066. [PMID: 26253911] - Tomohiro Morohoshi, Wen-Zhao Wang, Tomonori Suto, Yuki Saito, Satoshi Ito, Nobutaka Someya, Tsukasa Ikeda. Phenazine antibiotic production and antifungal activity are regulated by multiple quorum-sensing systems in Pseudomonas chlororaphis subsp. aurantiaca StFRB508.
Journal of bioscience and bioengineering.
2013 Nov; 116(5):580-4. doi:
10.1016/j.jbiosc.2013.04.022. [PMID: 23727350] - Mary Panijel, Laura Chalupowicz, Guido Sessa, Shulamit Manulis-Sasson, Isaac Barash. Global regulatory networks control the hrp regulon of the gall-forming bacterium Pantoea agglomerans pv. gypsophilae.
Molecular plant-microbe interactions : MPMI.
2013 Sep; 26(9):1031-43. doi:
10.1094/mpmi-04-13-0097-r. [PMID: 23745675] - Shuishan Song, Zhenhua Jia, Jinze Xu, Zhe Zhang, Zirui Bian. N-butyryl-homoserine lactone, a bacterial quorum-sensing signaling molecule, induces intracellular calcium elevation in Arabidopsis root cells.
Biochemical and biophysical research communications.
2011 Oct; 414(2):355-60. doi:
10.1016/j.bbrc.2011.09.076. [PMID: 21964296] - Olivier M Vandeputte, Martin Kiendrebeogo, Tsiry Rasamiravaka, Caroline Stévigny, Pierre Duez, Sanda Rajaonson, Billo Diallo, Adeline Mol, Marie Baucher, Mondher El Jaziri. The flavanone naringenin reduces the production of quorum sensing-controlled virulence factors in Pseudomonas aeruginosa PAO1.
Microbiology (Reading, England).
2011 Jul; 157(Pt 7):2120-2132. doi:
10.1099/mic.0.049338-0. [PMID: 21546585] - Alan R Smyth, Paramita M Cifelli, Catharine A Ortori, Karima Righetti, Sarah Lewis, Penny Erskine, Elaine D Holland, Michael Givskov, Paul Williams, Miguel Cámara, David A Barrett, Alan Knox. Garlic as an inhibitor of Pseudomonas aeruginosa quorum sensing in cystic fibrosis--a pilot randomized controlled trial.
Pediatric pulmonology.
2010 Apr; 45(4):356-62. doi:
10.1002/ppul.21193. [PMID: 20306535] - Olivier M Vandeputte, Martin Kiendrebeogo, Sanda Rajaonson, Billo Diallo, Adeline Mol, Mondher El Jaziri, Marie Baucher. Identification of catechin as one of the flavonoids from Combretum albiflorum bark extract that reduces the production of quorum-sensing-controlled virulence factors in Pseudomonas aeruginosa PAO1.
Applied and environmental microbiology.
2010 Jan; 76(1):243-53. doi:
10.1128/aem.01059-09. [PMID: 19854927] - Laura Chalupowicz, Shulamit Manulis-Sasson, Maxim Itkin, Ayelet Sacher, Guido Sessa, Isaac Barash. Quorum-sensing system affects gall development incited by Pantoea agglomerans pv. gypsophilae.
Molecular plant-microbe interactions : MPMI.
2008 Aug; 21(8):1094-105. doi:
10.1094/mpmi-21-8-1094. [PMID: 18616406] - Mokhlasur Rahman, Roger Simm, Abdul Kader, Eugenie Basseres, Ute Römling, Roland Möllby. The role of c-di-GMP signaling in an Aeromonas veronii biovar sobria strain.
FEMS microbiology letters.
2007 Aug; 273(2):172-9. doi:
10.1111/j.1574-6968.2007.00803.x. [PMID: 17573931] - Armando M Pomini, Luzia D Paccola-Meirelles, Anita J Marsaioli. Acyl-homoserine lactones produced by Pantoea sp. isolated from the 'maize white spot' foliar disease.
Journal of agricultural and food chemistry.
2007 Feb; 55(4):1200-4. doi:
10.1021/jf063136a. [PMID: 17256964] - An Yan, Xianqing Huang, Haiming Liu, Dexian Dong, Dabing Zhang, Xuehong Zhang, Yuquan Xu. An rhl-like quorum-sensing system negatively regulates pyoluteorin production in Pseudomonas sp. M18.
Microbiology (Reading, England).
2007 Jan; 153(Pt 1):16-28. doi:
10.1099/mic.0.29211-0. [PMID: 17185531]
