Aminohippurate sodium (BioDeep_00000859026)

   


代谢物信息卡片


Sodium [(4-aminobenzoyl)amino]acetate

化学式: C9H9N2NaO3 (216.0510844)
中文名称: 4-氨基马尿酸钠
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC(=CC=C1C(=O)NCC(=O)[O-])N.[Na+]
InChI: /q

描述信息

D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents

同义名列表

2 个代谢物同义名

Sodium [(4-aminobenzoyl)amino]acetate; Aminohippurate sodium



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Carissa Vinovskis, Lu-Ping Li, Pottumarthi Prasad, Kalie Tommerdahl, Laura Pyle, Robert G Nelson, Meda E Pavkov, Daniel van Raalte, Marian Rewers, Marlon Pragnell, Farid H Mahmud, David Z Cherney, Richard J Johnson, Kristen J Nadeau, Petter Bjornstad. Relative Hypoxia and Early Diabetic Kidney Disease in Type 1 Diabetes. Diabetes. 2020 12; 69(12):2700-2708. doi: 10.2337/db20-0457. [PMID: 32737116]
  • Weize Huang, Nina Isoherranen. Novel Mechanistic PBPK Model to Predict Renal Clearance in Varying Stages of CKD by Incorporating Tubular Adaptation and Dynamic Passive Reabsorption. CPT: pharmacometrics & systems pharmacology. 2020 10; 9(10):571-583. doi: 10.1002/psp4.12553. [PMID: 32977369]
  • Kelly E Mercer, Gabriella A M Ten Have, Lindsay Pack, Renny Lan, Nicolaas E P Deutz, Sean H Adams, Brian D Piccolo. Net release and uptake of xenometabolites across intestinal, hepatic, muscle, and renal tissue beds in healthy conscious pigs. American journal of physiology. Gastrointestinal and liver physiology. 2020 08; 319(2):G133-G141. doi: 10.1152/ajpgi.00153.2020. [PMID: 32538141]
  • Laura Dhondt, Siska Croubels, Pieter De Cock, Peter De Paepe, Siegrid De Baere, Mathias Devreese. Development and validation of an ultra-high performance liquid chromatography-tandem mass spectrometry method for the simultaneous determination of iohexol, p-aminohippuric acid and creatinine in porcine and broiler chicken plasma. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2019 Jun; 1117(?):77-85. doi: 10.1016/j.jchromb.2019.04.017. [PMID: 31004849]
  • Christian Ott, Agnes Bosch, Nicole Winzer, Stephanie Friedrich, Reinhard Schinzel, Frank Tegtmeier, Roland E Schmieder. Effects of the nitric oxide synthase inhibitor ronopterin (VAS203) on renal function in healthy volunteers. British journal of clinical pharmacology. 2019 05; 85(5):900-907. doi: 10.1111/bcp.13870. [PMID: 30666700]
  • Lukas Lannemyr, Sven-Erik Ricksten, Bengt Rundqvist, Bert Andersson, Sven-Erik Bartfay, Charlotta Ljungman, Pia Dahlberg, Niklas Bergh, Clara Hjalmarsson, Thomas Gilljam, Entela Bollano, Kristjan Karason. Differential Effects of Levosimendan and Dobutamine on Glomerular Filtration Rate in Patients With Heart Failure and Renal Impairment:A Randomized Double-Blind Controlled Trial. Journal of the American Heart Association. 2018 08; 7(16):e008455. doi: 10.1161/jaha.117.008455. [PMID: 30369310]
  • Yan-Rong Ma, Xuan Luo, Yan-Fang Wu, Tiffany Zhang, Fan Zhang, Guo-Qiang Zhang, Xin-An Wu. Alteration of renal excretion pathways in gentamicin-induced renal injury in rats. Journal of applied toxicology : JAT. 2018 07; 38(7):968-977. doi: 10.1002/jat.3603. [PMID: 29460972]
  • Shijie Wen, Changyuan Wang, Yingjie Duan, Xiaokui Huo, Qiang Meng, Zhihao Liu, Shilei Yang, Yanna Zhu, Huijun Sun, Xiaodong Ma, Siyun Yang, Kexin Liu. OAT1 and OAT3 also mediate the drug-drug interaction between piperacillin and tazobactam. International journal of pharmaceutics. 2018 Feb; 537(1-2):172-182. doi: 10.1016/j.ijpharm.2017.12.037. [PMID: 29277663]
  • I Fernández-Fígares, M Lachica, M L Rojas-Cano, A González-Casado. Influence of para-aminohippuric acid analysis on net portal-drained viscera flux of nutrients in pigs. Animal : an international journal of animal bioscience. 2018 Feb; 12(2):232-238. doi: 10.1017/s1751731117001598. [PMID: 28712380]
  • Yugo Hamada, Kenji Ikemura, Takuya Iwamoto, Masahiro Okuda. Stereoselective Inhibition of Renal Basolateral Human Organic Anion Transporter 3 by Lansoprazole Enantiomers. Pharmacology. 2018; 101(3-4):176-183. doi: 10.1159/000485920. [PMID: 29353278]
  • María Julia Severin, María Herminia Hazelhoff, Romina Paula Bulacio, María Eugenia Mamprin, Anabel Brandoni, Adriana Mónica Torres. Impact of the induced organic anion transporter 1 (Oat1) renal expression by furosemide on the pharmacokinetics of organic anions. Nephrology (Carlton, Vic.). 2017 Aug; 22(8):642-648. doi: 10.1111/nep.12838. [PMID: 27282888]
  • Hideki Uedono, Akihiro Tsuda, Eiji Ishimura, Shinya Nakatani, Masafumi Kurajoh, Katsuhito Mori, Junji Uchida, Masanori Emoto, Tatsuya Nakatani, Masaaki Inaba. U-shaped relationship between serum uric acid levels and intrarenal hemodynamic parameters in healthy subjects. American journal of physiology. Renal physiology. 2017 06; 312(6):F992-F997. doi: 10.1152/ajprenal.00645.2016. [PMID: 28249837]
  • Christin Fischer, Hauke Wessels, Angelika Paschke-Kratzin, Markus Fischer. Aptamers: Universal capture units for lateral flow applications. Analytical biochemistry. 2017 Apr; 522(?):53-60. doi: 10.1016/j.ab.2017.01.012. [PMID: 28111303]
  • Pietro Anastasio, Davide Viggiano, Miriam Zacchia, Claudia Altobelli, Giovambattista Capasso, Natale Gaspare De Santo. Delay in Renal Hemodynamic Response to a Meat Meal in Severe Obesity. Nephron. 2017; 136(2):151-157. doi: 10.1159/000453283. [PMID: 28329736]
  • U Krogh, A C Storm, P K Theil. Technical note: Measurement of mammary plasma flow in sows by downstream dilution of mammary vein infused -aminohippuric acid. Journal of animal science. 2016 Dec; 94(12):5122-5128. doi: 10.2527/jas.2016-0853. [PMID: 28046185]
  • T G Madsen, S R L Cieslar, D R Trout, M O Nielsen, J P Cant. Inhibition of local blood flow control systems in the mammary glands of lactating cows affects uptakes of energy metabolites from blood. Journal of dairy science. 2015 May; 98(5):3046-58. doi: 10.3168/jds.2014-8200. [PMID: 25747825]
  • Violeta Rodríguez-Romero, Karla I González-Villalva, José L Reyes, Rebecca E Franco-Bourland, Gabriel Guízar-Sahagún, Gilberto Castañeda-Hernández, Leticia Cruz-Antonio. A novel, simple and inexpensive procedure for the simultaneous determination of iopamidol and p-aminohippuric acid for renal function assessment from plasma samples in awake rats. Journal of pharmaceutical and biomedical analysis. 2015 Mar; 107(?):196-203. doi: 10.1016/j.jpba.2014.12.009. [PMID: 25594899]
  • Yohannes Hagos, Philip Hundertmark, Volodymyr Shnitsar, Venkata V V R Marada, Gerald Wulf, Gerhard Burckhardt. Renal human organic anion transporter 3 increases the susceptibility of lymphoma cells to bendamustine uptake. American journal of physiology. Renal physiology. 2015 Feb; 308(4):F330-8. doi: 10.1152/ajprenal.00467.2014. [PMID: 25477469]
  • Hideki Uedono, Akihiro Tsuda, Eiji Ishimura, Mari Yasumoto, Mitsuru Ichii, Akinobu Ochi, Yoshiteru Ohno, Shinya Nakatani, Katsuhito Mori, Junji Uchida, Tatsuya Nakatani, Masaaki Inaba. Relationship between serum uric acid levels and intrarenal hemodynamic parameters. Kidney & blood pressure research. 2015; 40(3):315-22. doi: 10.1159/000368507. [PMID: 26067715]
  • Kei Schulz, Yohannes Hagos, Gerhard Burckhardt, Gunnar Schley, Nikolai Burzlaff, Carsten Willam, Birgitta C Burckhardt. The Isoquinolone Derived Prolyl Hydroxylase Inhibitor ICA Is a Potent Substrate of the Organic Anion Transporters 1 and 3. Nephron. 2015; 131(4):285-9. doi: 10.1159/000442531. [PMID: 26640952]
  • Rym Chioukh, Marie-Sophie Noel-Hudson, Sandy Ribes, Natalie Fournier, Laurent Becquemont, Celine Verstuyft. Proton pump inhibitors inhibit methotrexate transport by renal basolateral organic anion transporter hOAT3. Drug metabolism and disposition: the biological fate of chemicals. 2014 Dec; 42(12):2041-8. doi: 10.1124/dmd.114.058529. [PMID: 25239859]
  • Adriaan A Voors, Marion Dahlke, Sven Meyer, Janina Stepinska, Stephen S Gottlieb, Andrew Jones, Yiming Zhang, Didier Laurent, Riemer H J A Slart, Gerjan J Navis. Renal hemodynamic effects of serelaxin in patients with chronic heart failure: a randomized, placebo-controlled study. Circulation. Heart failure. 2014 Nov; 7(6):994-1002. doi: 10.1161/circheartfailure.114.001536. [PMID: 25286914]
  • Jun Yan, Qi-Lei Zhang, Dong-Qiang Lin, Shan-Jing Yao. Protein adsorption behavior and immunoglobulin separation with a mixed-mode resin based on p-aminohippuric acid. Journal of separation science. 2014 Sep; 37(18):2474-80. doi: 10.1002/jssc.201400520. [PMID: 25044484]
  • Anne D Thuesen, Henrik Andersen, Majken Cardel, Anja Toft, Steen Walter, Niels Marcussen, Boye L Jensen, Peter Bie, Pernille B L Hansen. Differential effect of T-type voltage-gated Ca2+ channel disruption on renal plasma flow and glomerular filtration rate in vivo. American journal of physiology. Renal physiology. 2014 Aug; 307(4):F445-52. doi: 10.1152/ajprenal.00016.2014. [PMID: 24966091]
  • Kazuya Maeda, Ying Tian, Tomoe Fujita, Yasuhiko Ikeda, Yuji Kumagai, Tsunenori Kondo, Kazunari Tanabe, Hideki Nakayama, Shigeru Horita, Hiroyuki Kusuhara, Yuichi Sugiyama. Inhibitory effects of p-aminohippurate and probenecid on the renal clearance of adefovir and benzylpenicillin as probe drugs for organic anion transporter (OAT) 1 and OAT3 in humans. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 2014 Aug; 59(?):94-103. doi: 10.1016/j.ejps.2014.04.004. [PMID: 24747579]
  • Leslie Ingraham, Mansong Li, J Larry Renfro, Sonda Parker, Arpine Vapurcuyan, Imad Hanna, Ryan M Pelis. A plasma concentration of α-ketoglutarate influences the kinetic interaction of ligands with organic anion transporter 1. Molecular pharmacology. 2014 Jul; 86(1):86-95. doi: 10.1124/mol.114.091777. [PMID: 24770989]
  • Jenifer M Brown, Patricia C Underwood, Claudio Ferri, Paul N Hopkins, Gordon H Williams, Gail K Adler, Anand Vaidya. Aldosterone dysregulation with aging predicts renal vascular function and cardiovascular risk. Hypertension (Dallas, Tex. : 1979). 2014 Jun; 63(6):1205-11. doi: 10.1161/hypertensionaha.114.03231. [PMID: 24664291]
  • A Tsuda, E Ishimura, Y Ohno, M Ichii, S Nakatani, K Mori, S Fukumoto, M Emoto, M Inaba. Significant association of poor glycemic control with increased resistance in efferent arterioles--study of inulin and para-aminohippuric acid clearance in humans. Diabetes research and clinical practice. 2014 May; 104(2):234-40. doi: 10.1016/j.diabres.2014.01.030. [PMID: 24598266]
  • J M Rodríguez-López, G Cantalapiedra-Hijar, D Durand, A Isserty-Thomas, I Ortigues-Marty. Influence of the para-aminohippuric acid analysis method on the net hepatic flux of nutrients in lactating cows. Journal of animal science. 2014 Mar; 92(3):1074-82. doi: 10.2527/jas.2013-7359. [PMID: 24492558]
  • Ariane Bischoff, Michael Bucher, Michael Gekle, Christoph Sauvant. Differential effect of COX1 and COX2 inhibitors on renal outcomes following ischemic acute kidney injury. American journal of nephrology. 2014; 40(1):1-11. doi: 10.1159/000363251. [PMID: 24943263]
  • Katja Hueper, Marcel Gutberlet, Song Rong, Dagmar Hartung, Michael Mengel, Xia Lu, Hermann Haller, Frank Wacker, Martin Meier, Faikah Gueler. Acute kidney injury: arterial spin labeling to monitor renal perfusion impairment in mice-comparison with histopathologic results and renal function. Radiology. 2014 Jan; 270(1):117-24. doi: 10.1148/radiol.13130367. [PMID: 24023073]
  • S R L Cieslar, T G Madsen, N G Purdie, D R Trout, V R Osborne, J P Cant. Mammary blood flow and metabolic activity are linked by a feedback mechanism involving nitric oxide synthesis. Journal of dairy science. 2014; 97(4):2090-100. doi: 10.3168/jds.2013-6961. [PMID: 24508428]
  • Alexandra H Heussner, Daniel R Dietrich. Primary porcine proximal tubular cells as an alternative to human primary renal cells in vitro: an initial characterization. BMC cell biology. 2013 Dec; 14(?):55. doi: 10.1186/1471-2121-14-55. [PMID: 24308307]
  • V Rodríguez-Romero, L Cruz-Antonio, R E Franco-Bourland, G Guízar-Sahagún, G Castañeda-Hernández. Response to 'changes in renal function during acute spinal cord injury: implications for pharmacotherapy'. Spinal cord. 2013 Dec; 51(12):936. doi: 10.1038/sc.2013.125. [PMID: 24145688]
  • J R Silver. Changes in renal function during acute spinal cord injury: implications for pharmacotherapy. Spinal cord. 2013 Dec; 51(12):934-5. doi: 10.1038/sc.2013.124. [PMID: 24145686]
  • David Z I Cherney, Heather N Reich, James W Scholey, Denis Daneman, Farid H Mahmud, Ronnie L H Har, Etienne B Sochett. The effect of aliskiren on urinary cytokine/chemokine responses to clamped hyperglycaemia in type 1 diabetes. Diabetologia. 2013 Oct; 56(10):2308-17. doi: 10.1007/s00125-013-3000-3. [PMID: 23893332]
  • Akihiro Tsuda, Masaaki Inaba, Mitsuru Ichii, Akinobu Ochi, Yoshiteru Ohno, Shinya Nakatani, Shinsuke Yamada, Katsuhito Mori, Hideki Tahara, Eiji Ishimura. Relationship between serum TSH levels and intrarenal hemodynamic parameters in euthyroid subjects. European journal of endocrinology. 2013 Jul; 169(1):45-50. doi: 10.1530/eje-13-0026. [PMID: 23585555]
  • Noriko Takahara, Tsuneo Saga, Masayuki Inubushi, Hiroyuki Kusuhara, Chie Seki, Sumito Ito, Nobuyuki Oyama, Osamu Yokoyama, Yuichi Sugiyama, Yasuhisa Fujibayashi. Drugs interacting with organic anion transporter-1 affect uptake of Tc-99m-mercaptoacetyl-triglycine (MAG3) in the human kidney: therapeutic drug interaction in Tc-99m-MAG3 diagnosis of renal function and possible application of Tc-99m-MAG3 for drug development. Nuclear medicine and biology. 2013 Jul; 40(5):643-50. doi: 10.1016/j.nucmedbio.2013.03.006. [PMID: 23618840]
  • V Rodríguez-Romero, L Cruz-Antonio, R E Franco-Bourland, G Guízar-Sahagún, G Castañeda-Hernández. Changes in renal function during acute spinal cord injury: implications for pharmacotherapy. Spinal cord. 2013 Jul; 51(7):528-31. doi: 10.1038/sc.2013.35. [PMID: 23608810]
  • Johan Sällström, Markus Fridén. Simultaneous determination of renal plasma flow and glomerular filtration rate in conscious mice using dual bolus injection. Journal of pharmacological and toxicological methods. 2013 May; 67(3):187-93. doi: 10.1016/j.vascn.2013.01.010. [PMID: 23376812]
  • Justin Koteff, Julie Borland, Shuguang Chen, Ivy Song, Amanda Peppercorn, Takaaki Koshiba, Courtney Cannon, Heather Muster, Stephen C Piscitelli. A phase 1 study to evaluate the effect of dolutegravir on renal function via measurement of iohexol and para-aminohippurate clearance in healthy subjects. British journal of clinical pharmacology. 2013 Apr; 75(4):990-6. doi: 10.1111/j.1365-2125.2012.04440.x. [PMID: 22905856]
  • Atcharaporn Ontawong, Naruwan Saowakon, Pornpun Vivithanaporn, Anchalee Pongchaidecha, Narissara Lailerd, Doungporn Amornlerdpison, Anusorn Lungkaphin, Chutima Srimaroeng. Antioxidant and renoprotective effects of Spirogyra neglecta (Hassall) Kützing extract in experimental type 2 diabetic rats. BioMed research international. 2013; 2013(?):820786. doi: 10.1155/2013/820786. [PMID: 23862157]
  • Tao Liu, Qiang Meng, Changyuan Wang, Qi Liu, Xinjin Guo, Huijun Sun, Jinyong Peng, Xiaochi Ma, Taiichi Kaku, Kexin Liu. Changes in expression of renal Oat1, Oat3 and Mrp2 in cisplatin-induced acute renal failure after treatment of JBP485 in rats. Toxicology and applied pharmacology. 2012 Nov; 264(3):423-30. doi: 10.1016/j.taap.2012.08.019. [PMID: 22992436]
  • Yohannes Hagos, Gunnar Schley, Johannes Schödel, Wolfgang Krick, Gerhard Burckhardt, Carsten Willam, Birgitta C Burckhardt. α-Ketoglutarate-related inhibitors of HIF prolyl hydroxylases are substrates of renal organic anion transporters 1 (OAT1) and 4 (OAT4). Pflugers Archiv : European journal of physiology. 2012 Oct; 464(4):367-74. doi: 10.1007/s00424-012-1140-9. [PMID: 22875277]
  • Rais A Ansari, Syed A A Rizvi, Kazim Husain, Anastasios Lymperopoulos, William O Berndt. Effect of sulfhydryl modification on rat kidney basolateral plasma membrane transport function. Bulletin of environmental contamination and toxicology. 2012 Oct; 89(4):699-703. doi: 10.1007/s00128-012-0756-y. [PMID: 22936015]
  • Kathryn K Surdyk, Dawn L Sloan, Scott A Brown. Renal effects of carprofen and etodolac in euvolemic and volume-depleted dogs. American journal of veterinary research. 2012 Sep; 73(9):1485-90. doi: 10.2460/ajvr.73.9.1485. [PMID: 22924732]
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