Myochrysine (BioDeep_00000858933)
代谢物信息卡片
Myochrysine
化学式: C4H4AuNaO4S (367.93936040000006)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: [H+].C(C(C(=O)[O-])[S-])C(=O)[O-].[Na+].[Au+]
InChI: /q
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Mehdi Amirhosseini, Hammoudi Alkaissi, Per A Hultman, Said Havarinasab. Autoantibodies in outbred Swiss Webster mice following exposure to gold and mercury.
Toxicology and applied pharmacology.
2021 02; 412(?):115379. doi:
10.1016/j.taap.2020.115379. [PMID: 33358697] - Aaron S Mansfield, Alan P Fields, Aminah Jatoi, Yingwei Qi, Alex A Adjei, Charles Erlichman, Julian R Molina. Phase I dose escalation study of the PKCι inhibitor aurothiomalate for advanced non-small-cell lung cancer, ovarian cancer, and pancreatic cancer.
Anti-cancer drugs.
2013 Nov; 24(10):1079-83. doi:
10.1097/cad.0000000000000009. [PMID: 23962904] - Mohammad S Iqbal, Syed G Taqi, Muhammad Arif, Muhammad Wasim, Muhammad Sher. In vitro distribution of gold in serum proteins after incubation of sodium aurothiomalate and auranofin with human blood and its pharmacological significance.
Biological trace element research.
2009 Sep; 130(3):204-9. doi:
10.1007/s12011-009-8330-0. [PMID: 19194667] - Roderick P Regala, E Aubrey Thompson, Alan P Fields. Atypical protein kinase C iota expression and aurothiomalate sensitivity in human lung cancer cells.
Cancer research.
2008 Jul; 68(14):5888-95. doi:
10.1158/0008-5472.can-08-0438. [PMID: 18632643] - Paul L Wood, M Amin Khan, Joseph R Moskal. Mechanism of action of the disease-modifying anti-arthritic thiol agents D-penicillamine and sodium aurothiomalate: restoration of cellular free thiols and sequestration of reactive aldehydes.
European journal of pharmacology.
2008 Feb; 580(1-2):48-54. doi:
10.1016/j.ejphar.2007.10.066. [PMID: 18022616] - Alfredo de la Escosura-Muñiz, María Begoña González-García, Agustín Costa-García. Determination of human serum albumin using aurothiomalate as electroactive label.
Analytical and bioanalytical chemistry.
2006 Feb; 384(3):742-50. doi:
10.1007/s00216-005-0213-4. [PMID: 16372180] - Shoji Sugii. [Adverse effects of DMARDs in treatment of rheumatoid arthritis].
Nihon rinsho. Japanese journal of clinical medicine.
2005 Jan; 63 Suppl 1(?):566-72. doi:
NULL. [PMID: 15799419] - Aida Chircorian, Amy M Barrios. Inhibition of lysosomal cysteine proteases by chrysotherapeutic compounds: a possible mechanism for the antiarthritic activity of Au(I).
Bioorganic & medicinal chemistry letters.
2004 Oct; 14(20):5113-6. doi:
10.1016/j.bmcl.2004.07.073. [PMID: 15380210] - Sofia Ernestam, Jon Lampa, Siv Rogberg, Johan Rönnelid, Lars Klareskog, Ingiäld Hafström. Evidence for immunostimulatory effects of intramuscular gold in patients with rheumatoid arthritis: correlation with skin reactions.
The Journal of rheumatology.
2003 Aug; 30(8):1748-55. doi:
NULL. [PMID: 12913930] - T K Kvien, H K Zeidler, P Hannonen, F A Wollheim, O Førre, I Hafström, J P Kaltwasser, M Leirisalo-Repo, B Manger, L Laasonen, H Prestele, P Kurki. Long term efficacy and safety of cyclosporin versus parenteral gold in early rheumatoid arthritis: a three year study of radiographic progression, renal function, and arterial hypertension.
Annals of the rheumatic diseases.
2002 Jun; 61(6):511-6. doi:
10.1136/ard.61.6.511. [PMID: 12006323] - Ake Svensson, Halvor Möller, Bert Björkner, Magnus Bruze, Ido Leden, Jan Theander, Kjell Ohlsson, Carina Linder. Rheumatoid arthritis, gold therapy, contact allergy and blood cytokines.
BMC dermatology.
2002; 2(?):2. doi:
10.1186/1471-5945-2-2. [PMID: 11860615] - K Kishimoto, K Iwatsuki, H Akiba, Y Motoki, F Kaneko. Subcorneal pustular dermatosis-type IgA pemphigus induced by thiol drugs.
European journal of dermatology : EJD.
2001 Jan; 11(1):41-4. doi:
NULL. [PMID: 11174137] - M Nagashima, K Wauke, D Hirano, S Ishigami, H Aono, M Takai, M Sasano, S Yoshino. Effects of combinations of anti-rheumatic drugs on the production of vascular endothelial growth factor and basic fibroblast growth factor in cultured synoviocytes and patients with rheumatoid arthritis.
Rheumatology (Oxford, England).
2000 Nov; 39(11):1255-62. doi:
10.1093/rheumatology/39.11.1255. [PMID: 11085806] - H Kamei, T Koide, T Koijima, Y Hashimoto, M Hasegawa. Effect of gold on tumor-associated antigens.
Cancer biotherapy & radiopharmaceuticals.
1999 Oct; 14(5):403-6. doi:
10.1089/cbr.1999.14.403. [PMID: 10850325] - G Pistritto, O Franzese, G Pozzoli, C Mancuso, G Tringali, P Preziosi, P Navarra. Bacterial lipopolysaccharide increases prostaglandin production by rat astrocytes via inducible cyclo-oxygenase: evidence for the involvement of nuclear factor kappaB.
Biochemical and biophysical research communications.
1999 Sep; 263(2):570-4. doi:
10.1006/bbrc.1999.1413. [PMID: 10491333] - A L Herrick, R Hodgkiss, P Reed, C Weinkove, M I Jayson, B Houston. No significant effects of sodium aurothiomalate on haem metabolism and mixed function oxygenase activity in patients with rheumatoid arthritis.
Clinical and experimental rheumatology.
1999 Jul; 17(4):461-2. doi:
NULL. [PMID: 10464558] - T Oba, T Ishikawa, M Yamaguchi. Different effects of two gold compounds on muscle contraction, membrane potential and ryanodine receptor.
European journal of pharmacology.
1999 Jun; 374(3):477-87. doi:
10.1016/s0014-2999(99)00317-9. [PMID: 10422793] - H Möller, K Ohlsson, C Linder, B Björkner, M Bruze. The flare-up reactions after systemic provocation in contact allergy to nickel and gold.
Contact dermatitis.
1999 Apr; 40(4):200-4. doi:
10.1111/j.1600-0536.1999.tb06034.x. [PMID: 10208507] - P Wiland, J Szechiński. N-acetyl-beta-D-glucosaminidase urinary excretion as an early indicator of kidney damage in rheumatoid arthritis patients starting on parenteral gold and Depo-Medrone/placebo injections.
Clinical rheumatology.
1999; 18(2):106-13. doi:
10.1007/s100670050066. [PMID: 10357114] - J D Jessop, M M O'Sullivan, P A Lewis, L A Williams, J P Camilleri, M J Plant, E C Coles. A long-term five-year randomized controlled trial of hydroxychloroquine, sodium aurothiomalate, auranofin and penicillamine in the treatment of patients with rheumatoid arthritis.
British journal of rheumatology.
1998 Sep; 37(9):992-1002. doi:
10.1093/rheumatology/37.9.992. [PMID: 9783766] - H Möller, K Ohlsson, C Linder, B Björkner, M Bruze. Cytokines and acute phase reactants during flare-up of contact allergy to gold.
American journal of contact dermatitis : official journal of the American Contact Dermatitis Society.
1998 Mar; 9(1):15-22. doi:
NULL. [PMID: 9471982] - F Shabani, J McNeil, L Tippett. The oxidative inactivation of tissue inhibitor of metalloproteinase-1 (TIMP-1) by hypochlorous acid (HOCI) is suppressed by anti-rheumatic drugs.
Free radical research.
1998 Feb; 28(2):115-23. doi:
10.3109/10715769809065797. [PMID: 9645388] - P P Sfikakis, M A Dimopoulos, V L Souliotis, D Charalambopoulos, M Mavrikakis, P Panayiotidis. Effects of 2-chlorodeoxyadenosine and gold sodium thiomalate on human bcl-2 gene expression.
Immunopharmacology and immunotoxicology.
1998 Feb; 20(1):63-77. doi:
10.3109/08923979809034809. [PMID: 9543700] - H K Koryem, K M Taha, I K Ibrahim, L K Younes. Liver toxicity profile in gold-treated Egyptian rheumatoid arthritis patients.
International journal of clinical pharmacology research.
1998; 18(1):31-7. doi:
NULL. [PMID: 9604732] - T Vlak, B Stambuk. [Comparative study of the effects of auranofin and aurothiomalate on laboratory and clinical indicators in patients with rheumatoid arthritis].
Reumatizam.
1998; 46(1):7-19. doi:
NULL. [PMID: 9921004] - J Reglinski, D E Paterson, S Latimer, J M Campbell, R Wilson, D Porter, R D Sturrock, W E Smith. Myocrisin-mediated oxidative stress.
Clinica chimica acta; international journal of clinical chemistry.
1997 Dec; 268(1-2):85-99. doi:
10.1016/s0009-8981(97)00170-8. [PMID: 9495573] - J Nishio, R Koike, H Iizuka, T Nanki, N Mizushima, H Kohsaka, T Kubota, N Miyasaka. [A refractory case of adult-onset Still's disease].
Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology.
1997 Jun; 20(3):191-8. doi:
10.2177/jsci.20.191. [PMID: 9256612] - R Munro, E Morrison, A G McDonald, J A Hunter, R Madhok, H A Capell. Effect of disease modifying agents on the lipid profiles of patients with rheumatoid arthritis.
Annals of the rheumatic diseases.
1997 Jun; 56(6):374-7. doi:
10.1136/ard.56.6.374. [PMID: 9227167] - K Ujiie, T Shiigai. [Gold nephropathy].
Ryoikibetsu shokogun shirizu.
1997; ?(16 Pt 1):529-30. doi:
NULL. [PMID: 9277807] - C Beyeler, B M Frey, H A Bird. Urinary 6 beta-hydroxycortisol excretion in rheumatoid arthritis.
British journal of rheumatology.
1997 Jan; 36(1):54-8. doi:
10.1093/rheumatology/36.1.54. [PMID: 9117175] - A Kaipia, S Y Chun, K Eisenhauer, A J Hsueh. Tumor necrosis factor-alpha and its second messenger, ceramide, stimulate apoptosis in cultured ovarian follicles.
Endocrinology.
1996 Nov; 137(11):4864-70. doi:
10.1210/endo.137.11.8895358. [PMID: 8895358] - P A Merkel, M A Dooley, D V Dawson, D S Pisetsky, R P Polisson. Interleukin-2 receptor levels in sera of patients with rheumatoid arthritis treated with sulfasalazine, parenteral gold, or placebo.
The Journal of rheumatology.
1996 Nov; 23(11):1856-61. doi:
NULL. [PMID: 8923356] - M Koda, S Yoshino, H Nakamura, G Asano. [Effects of disease modifying antirheumatic drugs (DMARDs) and DEX on IL-1 beta and IL-6 production by IL-1 beta stimulated synovial culture cells].
Nihon Ika Daigaku zasshi.
1996 Oct; 63(5):419-23. doi:
10.1272/jnms1923.63.419. [PMID: 8937133] - N Snowden, D M Dietch, L S Teh, R C Hilton, M R Haeney. Antibody deficiency associated with gold treatment: natural history and management in 22 patients.
Annals of the rheumatic diseases.
1996 Sep; 55(9):616-21. doi:
10.1136/ard.55.9.616. [PMID: 8882131] - C Beyeler, R Banks, D Thompson, M A Forbes, E H Cooper, H A Bird. Bone alkaline phosphatase in rheumatoid arthritis: a longitudinal study.
The Journal of rheumatology.
1996 Feb; 23(2):241-4. doi:
. [PMID: 8882026] - T Ogura, M Takaoka, T Yamauchi, T Oishi, Y Mimura, M Hashimoto, N Asano, M Yamamura, F Otsuka, H Makino, Z Ota, K Takahashi. Changes in urinary enzyme activity and histochemical findings in experimental tubular injury induced by gold sodium thiomalate.
Journal of medicine.
1996; 27(1-2):41-55. doi:
NULL. [PMID: 8863177] - E Cheriathundam, A P Alvares. Species differences in the renal toxicity of the antiarthritic drug, gold sodium thiomalate.
Journal of biochemical toxicology.
1996; 11(4):175-81. doi:
10.1002/(sici)1522-7146(1996)11:4<175::aid-jbt2>3.0.co;2-h. [PMID: 9062847] - J Christodoulou, P J Sadler, A Tucker. 1H NMR of albumin in human blood plasma: drug binding and redox reactions at Cys34.
FEBS letters.
1995 Nov; 376(1-2):1-5. doi:
10.1016/0014-5793(95)01231-2. [PMID: 8521951] - S Suzuki, M Okubo, S Kaise, M Ohara, R Kasukawa. Gold sodium thiomalate selectivity inhibits interleukin-5-mediated eosinophil survival.
The Journal of allergy and clinical immunology.
1995 Aug; 96(2):251-6. doi:
10.1016/s0091-6749(95)70015-3. [PMID: 7636062] - K Maeda, K Komuta, K Hasegawa, M Ohtsuki, H Morishita, T Igarashi. [A case of interstitial pneumonia in polymyositis difficult to distinguish from gold pneumonitis].
Nihon Kyobu Shikkan Gakkai zasshi.
1995 Jul; 33(7):745-9. doi:
NULL. [PMID: 7564001] - T Saito, S Nishi, R Karasawa, H In, H Hayashi, M Ueno, S Ogino, N Sugiyama, S Suzuki, Y Maruyama. An ultrastructural study of glomerular basement membrane in rheumatoid arthritis patients with urinary abnormalities.
Clinical nephrology.
1995 Jun; 43(6):360-7. doi:
NULL. [PMID: 7554519] - S J Mandel, G A Brent, M Weinblatt, P R Larsen. Prospective studies of thyroid function in patients receiving gold therapy.
Thyroid : official journal of the American Thyroid Association.
1995 Apr; 5(2):113-6. doi:
10.1089/thy.1995.5.113. [PMID: 7647570] - Y Takahashi, T Funakoshi, H Shimada, S Kojima. The utility of chelating agents as antidotes for nephrotoxicity of gold sodium thiomalate in adjuvant-arthritic rats.
Toxicology.
1995 Mar; 97(1-3):151-7. doi:
10.1016/0300-483x(94)02944-p. [PMID: 7716781] - C McDonald, P Mortimer, G McAllister, P E Gardiner, J Reglinski, W E Smith. A comparative study of the interaction of Myocrisin with albumin and gamma-globulin.
Journal of pharmaceutical and biomedical analysis.
1995 Feb; 13(2):99-102. doi:
10.1016/0731-7085(94)00118-l. [PMID: 7539297] - J Lewandowicz, B Dabkowska, D Nowak. Influence of gold salts treatment on the serum concentration of IL-1 and IL-2 in patients with rheumatoid arthritis.
Archivum immunologiae et therapiae experimentalis.
1995; 43(3-4):195-8. doi:
NULL. [PMID: 8744695] - M Shingu, Y Fujikawa, T Wada, S Nonaka, M Nobunaga. Increased IL-1 receptor antagonist (IL-1ra) production and decreased IL-1 beta/IL-1ra ratio in mononuclear cells from rheumatoid arthritis patients.
British journal of rheumatology.
1995 Jan; 34(1):24-30. doi:
10.1093/rheumatology/34.1.24. [PMID: 7881833] - T Tonn, C Goebel, M Wilhelm, E Gleichmann. Gold kinetics under long-term treatment with gold(I) disodium thiomalate: a comparison in three different mouse strains.
British journal of rheumatology.
1994 Aug; 33(8):724-30. doi:
10.1093/rheumatology/33.8.724. [PMID: 8055198] - M C Pérez, M T Gómez Casares, R Mataix, C Campo, S Jiménez, J J Malcorra. [Bone marrow aplasia and gold salts. Review of the literature apropos of 2 cases].
Revista clinica espanola.
1994 Jul; 194(7):540-2. doi:
NULL. [PMID: 7938822] - E De Miguel, F Arnalich, E Tato, J J Vázquez, J Gijón-Baños, A Hernanz. The effect of gold salts on substance P levels in rheumatoid arthritis.
Neuroscience letters.
1994 Jun; 174(2):185-7. doi:
10.1016/0304-3940(94)90017-5. [PMID: 7526289] - K Hashimoto, C E Whitehurst, P E Lipsky. Synergistic inhibition of T cell proliferation by gold sodium thiomalate and auranofin.
The Journal of rheumatology.
1994 Jun; 21(6):1020-6. doi:
NULL. [PMID: 7932408] - Y Takahashi, T Funakoshi, H Shimada, S Kojima. Comparative effects of chelating agents on distribution, excretion, and renal toxicity of gold sodium thiomalate in rats.
Toxicology.
1994 May; 90(1-2):39-51. doi:
10.1016/0300-483x(94)90203-8. [PMID: 8023341] - R Saura, T Matsubara, K Mizuno. Inhibition of neovascularization in vivo by gold compounds.
Rheumatology international.
1994; 14(1):1-7. doi:
10.1007/bf00302664. [PMID: 7939134] - R A Brown, J More, O S Ejim. Preparation of a gelatin-binding conjugate containing gold thiomalate.
Arzneimittel-Forschung.
1993 Jun; 43(6):682-5. doi:
NULL. [PMID: 8352823] - S Hirohata, C Kawashima, S Shinohara, T Sawada, Y Nishioka, S Tohma, T Kisaki, T Inoue, S Iwamoto, K Ito. [Analysis of the state of patients with rheumatoid arthritis using a personal computer].
Ryumachi. [Rheumatism].
1993 Apr; 33(2):131-41. doi:
NULL. [PMID: 8316903] - R Madhok, A Crilly, E Murphy, J Smith, J Watson, H A Capell. Gold therapy lowers serum interleukin 6 levels in rheumatoid arthritis.
The Journal of rheumatology.
1993 Apr; 20(4):630-3. doi:
NULL. [PMID: 8496855] - L I Sakkas, I C Chikanza, R W Vaughan, K I Welsh, G S Panayi. Gold induced nephropathy in rheumatoid arthritis and HLA class II genes.
Annals of the rheumatic diseases.
1993 Apr; 52(4):300-1. doi:
10.1136/ard.52.4.300. [PMID: 8484697] - R C Elder, Z Zhao, Y Zhang, J G Dorsey, E V Hess, K Tepperman. Dicyanogold (I) is a common human metabolite of different gold drugs.
The Journal of rheumatology.
1993 Feb; 20(2):268-72. doi:
NULL. [PMID: 8474063] - A Maïza, P T Daley-Yates. Variability in the renal clearance of cephalexin in experimental renal failure.
Journal of pharmacokinetics and biopharmaceutics.
1993 Feb; 21(1):19-30. doi:
10.1007/bf01061773. [PMID: 8410681] - K M McKague, C J Lock, F McCrae, W E Smith, H Buchanan, W F Kean, J Reglinski. Site of action for the inhibition by gold sodium thiomalate of rabbit platelet activation.
Journal of pharmaceutical sciences.
1993 Feb; 82(2):174-8. doi:
10.1002/jps.2600820212. [PMID: 8445531] - A Crilly, R Madhok, J Watson, H A Capell. Serum concentrations of soluble interleukin 2 receptor in patients with rheumatoid arthritis: effect of second line drugs.
Annals of the rheumatic diseases.
1993 Jan; 52(1):58-60. doi:
10.1136/ard.52.1.58. [PMID: 8093995] - S Tiitinen, K Kaarela, H Helin, H Kautiainen, H Isomäki. Amyloidosis--incidence and early risk factors in patients with rheumatoid arthritis.
Scandinavian journal of rheumatology.
1993; 22(4):158-61. doi:
10.3109/03009749309099264. [PMID: 8356407] - Y Yamanishi, M Takeda, N Honjo, K Aoi, Y Ishibe, S Yamana. [Gold-induced severe cholestatic jaundice in rheumatoid arthritis patient and effect of repeated steroid pulse therapy].
Ryumachi. [Rheumatism].
1992 Oct; 32(5):475-82; discussion 480. doi:
NULL. [PMID: 1440084] - J Egila, D Littlejohn, W E Smith, R D Sturrock. Gold concentrations in blood fractions of patients with rheumatoid arthritis treated with Myocrisin.
Journal of pharmaceutical and biomedical analysis.
1992 Sep; 10(9):639-44. doi:
10.1016/0731-7085(92)80091-z. [PMID: 1286129] - S Kojima, Y Takahashi, M Kiyozumi, T Funakoshi, H Shimada. Characterization of gold in urine and bile following administration of gold sodium thiomalate with chelating agents to rats.
Toxicology.
1992 Aug; 74(1):1-8. doi:
10.1016/0300-483x(92)90038-g. [PMID: 1325079] - Y Takahashi, T Funakoshi, H Shimada, M Kiyozumi, S Kojima. Effect of repeated administration of chelating agents on distribution, excretion, and renal toxicity of gold sodium thiomalate in rats.
Research communications in chemical pathology and pharmacology.
1992 May; 76(2):253-6. doi:
NULL. [PMID: 1604050] - H Tanaka, K Nakahara, K Goto. [A case of bucillamine-induced pneumonitis].
Nihon Kyobu Shikkan Gakkai zasshi.
1992 Apr; 30(4):695-701. doi:
". [PMID: 1405091] - Z Zhao, W B Jones, K Tepperman, J G Dorsey, R C Elder. Determination of gold-based antiarthritis drugs and their metabolites in urine by reversed-phase ion-pair chromatography with ICP-MS detection.
Journal of pharmaceutical and biomedical analysis.
1992 Apr; 10(4):279-87. doi:
10.1016/0731-7085(92)80040-t. [PMID: 1420457] - A A Isab. The 13C NMR study of the binding of gold(I) thiomalate with ergothionine in aqueous solution.
Journal of inorganic biochemistry.
1992 Mar; 45(4):261-7. doi:
10.1016/0162-0134(92)84014-e. [PMID: 1619402] - T Vlak, I Jajić. [The effect of Na-aurothiomalate on circulating immune complex dynamics in patients with rheumatoid arthritis].
Reumatizam.
1992; 39(2):1-5. doi:
NULL. [PMID: 1366145] - M Seitz, B Dewald, M Ceska, N Gerber, M Baggiolini. Interleukin-8 in inflammatory rheumatic diseases: synovial fluid levels, relation to rheumatoid factors, production by mononuclear cells, and effects of gold sodium thiomalate and methotrexate.
Rheumatology international.
1992; 12(4):159-64. doi:
10.1007/bf00274936. [PMID: 1439483] - Y M Sin, M K Wong. Effect of sodium aurothiomalate on carrageenan induced inflammation of the air pouch in mice.
Annals of the rheumatic diseases.
1992 Jan; 51(1):112-6. doi:
10.1136/ard.51.1.112. [PMID: 1540014] - T Vlak, I Jajić. [Complement (C3 and C4) in patients with rheumatoid arthritis during 6 months of treatment with gold salts].
Reumatizam.
1992; 39(1):7-10. doi:
NULL. [PMID: 1366144] - T Vlak, Z Jajić. [The effect of Tauredon on the development of non-specific indicators of inflammatory activity in patients with rheumatoid arthritis].
Reumatizam.
1992; 39(1):19-22. doi:
NULL. [PMID: 1366140] - W F Kean, C J Lock, D Somers, J Rischke, L Nablo, Y B Kassam, M G Hogan, W W Buchanan, H E Howard-Lock. Action of gold sodium thiomalate on experimental thrombosis in vivo.
Journal of pharmaceutical sciences.
1991 Feb; 80(2):113-8. doi:
10.1002/jps.2600800205. [PMID: 1904936] - S Kojima, Y Takahashi, M Kiyozumi, Y Tagawa. Protective effects of chelating agents against renal toxicity of gold sodium thiomalate in rats.
Archives of toxicology.
1991; 65(7):532-6. doi:
10.1007/bf01973712. [PMID: 1664200] - C F Shaw, D H Petering, J E Laib, M M Savas, K Melnick. In vitro preparation and characterization of aurothioneins.
Methods in enzymology.
1991; 205(?):469-75. doi:
10.1016/0076-6879(91)05132-f. [PMID: 1779810] - N V Chichasova, M Z Kanevskaia, G A Slobodina, V A Varshavskiĭ, O V Krel', A A Krel'. [A comparative evaluation of parenteral and oral preparations of gold and D-penicillamine in the treatment of rheumatoid nephropathy].
Terapevticheskii arkhiv.
1991; 63(5):97-101. doi:
NULL. [PMID: 1679571] - M Grootveld, A W Claxson, D Naughton, M Whelan, A Furst, D R Blake. Influence of an intravenous dose of aurothiomalate on the status of low-molecular-mass endogenous metabolites in blood plasma: a proton nuclear magnetic resonance (NMR) study.
Agents and actions. Supplements.
1991; 32(?):65-9. doi:
10.1007/978-3-0348-7405-2_8. [PMID: 1906237] - R Rau, M Schattenkirchner, H Muller-Fassbender, B Kaik, H Zeidler, B Missler. A three year comparative study of auranofin and gold sodium thiomalate in rheumatoid arthritis.
Clinical rheumatology.
1990 Dec; 9(4):461-74. doi:
10.1007/bf02030507. [PMID: 2128475] - D Schuhmann, M Kubicka-Muranyi, J Mirtschewa, J Günther, P Kind, E Gleichmann. Adverse immune reactions to gold. I. Chronic treatment with an Au(I) drug sensitizes mouse T cells not to Au(I), but to Au(III) and induces autoantibody formation.
Journal of immunology (Baltimore, Md. : 1950).
1990 Oct; 145(7):2132-9. doi:
NULL. [PMID: 2118929] - P N Bennett, S J Humphries, J P Osborne, A K Clarke, A Taylor. Use of sodium aurothiomalate during lactation.
British journal of clinical pharmacology.
1990 Jun; 29(6):777-9. doi:
10.1111/j.1365-2125.1990.tb03703.x. [PMID: 2116162] - G G Graham, M M Dale. The activation of gold complexes by cyanide produced by polymorphonuclear leukocytes--II. Evidence for the formation and biological activity of aurocyanide.
Biochemical pharmacology.
1990 Jun; 39(11):1697-702. doi:
10.1016/0006-2952(90)90113-y. [PMID: 2160818] - V A Danis, A J Kulesz, D S Nelson, P M Brooks. The effect of gold sodium thiomalate and auranofin on lipopolysaccharide-induced interleukin-1 production by blood monocytes in vitro: variation in healthy subjects and patients with arthritis.
Clinical and experimental immunology.
1990 Mar; 79(3):335-40. doi:
10.1111/j.1365-2249.1990.tb08092.x. [PMID: 2107989] - G T Thomson, J L Johnston, F D Baragar, J W Toole. Psoriatic arthritis and myopathy.
The Journal of rheumatology.
1990 Mar; 17(3):395-8. doi:
NULL. [PMID: 2110253] - A Yan, P Davis. Gold induced marrow suppression: a review of 10 cases.
The Journal of rheumatology.
1990 Jan; 17(1):47-51. doi:
NULL. [PMID: 2107305] - M T Walters, F K Stevenson, R Goswami, J L Smith, M I Cawley. Comparison of serum and synovial fluid concentrations of beta 2-microglobulin and C reactive protein in relation to clinical disease activity and synovial inflammation in rheumatoid arthritis.
Annals of the rheumatic diseases.
1989 Nov; 48(11):905-11. doi:
10.1136/ard.48.11.905. [PMID: 2512862] - G F Evans, S H Zuckerman. Pharmacologic modulation of TNF production by endotoxin stimulated macrophages: in vitro and in vivo effects of auranofin and other chrysotherapeutic compounds.
Agents and actions.
1989 Mar; 26(3-4):329-34. doi:
10.1007/bf01967297. [PMID: 2500010] - M Mihara, Y Ohsugi. Effect of several kinds of drugs on the development of autoimmunity in MRL/Mp-lpr/lpr mice; lack of correlation between the suppression of autoantibody production and prevention of autoimmune disease.
Journal of pharmacobio-dynamics.
1989 Feb; 12(2):100-6. doi:
10.1248/bpb1978.12.100. [PMID: 2526211] - P Pietsch, H W Vohr, K Degitz, E Gleichmann. Immunological alterations inducible by mercury compounds. II. HgCl2 and gold sodium thiomalate enhance serum IgE and IgG concentrations in susceptible mouse strains.
International archives of allergy and applied immunology.
1989; 90(1):47-53. doi:
NULL. [PMID: 2509376] - T Matsubara, R Saura, K Hirohata, M Ziff. Inhibition of human endothelial cell proliferation in vitro and neovascularization in vivo by D-penicillamine.
The Journal of clinical investigation.
1989 Jan; 83(1):158-67. doi:
10.1172/jci113853. [PMID: 2463265] - J E Parente, M P Walsh, P R Girard, J F Kuo, D S Ng, K Wong. Effects of gold coordination complexes on neutrophil function are mediated via inhibition of protein kinase C.
Molecular pharmacology.
1989 Jan; 35(1):26-33. doi:
. [PMID: 2536465] - M H Rayner, M Grootveld, P J Sadler. Molecular distribution of gold(I) in human blood plasma after treatment with the antiarthritic disodium aurothiomalate.
International journal of clinical pharmacology research.
1989; 9(6):377-83. doi:
NULL. [PMID: 2517496] - T Matsubara, Y Saegusa, K Hirohata. Low-dose gold compounds inhibit fibroblast proliferation and do not affect interleukin-1 secretion by macrophages.
Arthritis and rheumatism.
1988 Oct; 31(10):1272-80. doi:
10.1002/art.1780311009. [PMID: 3140819] - K M Connolly, V J Stecher, E Danis, D J Pruden, T LaBrie. Alteration of interleukin-1 activity and the acute phase response in adjuvant arthritic rats treated with disease modifying antirheumatic drugs.
Agents and actions.
1988 Aug; 25(1-2):94-105. doi:
10.1007/bf01969100. [PMID: 3142230] - R Madhok, H A Capell. Cyclosporine A in rheumatoid arthritis: results at 30 months.
Transplantation proceedings.
1988 Jun; 20(3 Suppl 4):248-52. doi:
NULL. [PMID: 3132774] - P M Graabaek, S M Pedersen. Effect of two gold compounds on lysosomes.
Annals of the rheumatic diseases.
1988 Jun; 47(6):509-14. doi:
10.1136/ard.47.6.509. [PMID: 3132900] - J S Dixon, M Greenwood, H A Bird. How reliable is ESR as a measure of disease activity in rheumatoid arthritis treated with hydroxychloroquine?.
Clinical rheumatology.
1988 Jun; 7(2):262-6. doi:
10.1007/bf02204465. [PMID: 2901304] - M J Heath. Measurement of 'free' gold in patients receiving disodium aurothiomalate and the association of high free to total gold levels with toxicity.
Annals of the rheumatic diseases.
1988 Jan; 47(1):18-21. doi:
10.1136/ard.47.1.18. [PMID: 3125798] - E Seppälä, K Lehtinen, H Isomäki, M Nissilä, A Harmoinen, P Mörsky, T Koivula, H Vapaatalo. Effects of long-term aurothiomalate and D-penicillamine treatments on renal function and urinary excretion of prostanoids in patients with rheumatoid arthritis.
International journal of clinical pharmacology research.
1988; 8(3):149-56. doi:
. [PMID: 3136089]