Zolpidem tartrate (BioDeep_00000858931)
代谢物信息卡片
化学式: C42H48N6O8 (764.3533448000001)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1=CC=C(C=C1)C2=C(N3C=C(C=CC3=N2)C)CC(=O)N(C)C.CC1=CC=C(C=C1)C2=C(N3C=C(C=CC3=N2)C)CC(=O)N(C)C.C(C(C(=O)O)O)(C(=O)O)O
InChI: 1-,2-/m..1/s1
描述信息
D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D006993 - Hypnotics and Sedatives
D018377 - Neurotransmitter Agents > D018682 - GABA Agents > D018755 - GABA Agonists
C78272 - Agent Affecting Nervous System > C29756 - Sedative and Hypnotic
同义名列表
1 个代谢物同义名
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Q Zhang, M Zhang, Y Liu, Y Wang, F Lv, Y Wang. [Exploring the therapeutic mechanism of Liuwei Suanzao decoction for perimenopausal insomnia based on network pharmacology and animal experiments].
Nan fang yi ke da xue xue bao = Journal of Southern Medical University.
2023 Sep; 43(9):1536-1547. doi:
10.12122/j.issn.1673-4254.2023.09.11. [PMID: 37814868] - Zhennan Xiao, Bo Long, Zeji Zhao. The Effect of Improving Preoperative Sleep Quality on Perioperative Pain by Zolpidem in Patients Undergoing Laparoscopic Colorectal Surgery: A Prospective, Randomized Study.
Pain research & management.
2022; 2022(?):3154780. doi:
10.1155/2022/3154780. [PMID: 35069955] - O V Kotova, E V Tsareva, V E Medvedev, A A Belyaev, E V Gushanskaya, V I Frolova, I G Kotelnikova. [Clinical aspects of the use of imidazopyridine derivatives in the treatment of sleep disorders associated with post-COVID syndrome].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova.
2022; 122(12):39-44. doi:
10.17116/jnevro202212212139. [PMID: 36537629] - Xijun Zheng, Yingchun He, Fang Yin, Hongxia Liu, Yunfei Li, Qingshan Zheng, Lujin Li. Pharmacological interventions for the treatment of insomnia: quantitative comparison of drug efficacy.
Sleep medicine.
2020 08; 72(?):41-49. doi:
10.1016/j.sleep.2020.03.022. [PMID: 32544795] - Sangoh Kwon, Minseok Yoon, Jaekwang Lee, Kwang-Deog Moon, Dohyeon Kim, Seon-Bong Kim, Suengmok Cho. A Standardized Phlorotannin Supplement Attenuates Caffeine-Induced Sleep Disruption in Mice.
Nutrients.
2019 Mar; 11(3):. doi:
10.3390/nu11030556. [PMID: 30845636] - Daniel Flesch, Sun-Yee Cheung, Jurema Schmidt, Matthias Gabler, Pascal Heitel, Jan Kramer, Astrid Kaiser, Markus Hartmann, Mara Lindner, Kerstin Lüddens-Dämgen, Jan Heering, Christina Lamers, Hartmut Lüddens, Mario Wurglics, Ewgenij Proschak, Manfred Schubert-Zsilavecz, Daniel Merk. Nonacidic Farnesoid X Receptor Modulators.
Journal of medicinal chemistry.
2017 08; 60(16):7199-7205. doi:
10.1021/acs.jmedchem.7b00903. [PMID: 28749691] - Hyejin Yang, Junsung Woo, Ae Nim Pae, Min Young Um, Nam-Chul Cho, Ki Duk Park, Minseok Yoon, Jiyoung Kim, C Justin Lee, Suengmok Cho. α-Pinene, a Major Constituent of Pine Tree Oils, Enhances Non-Rapid Eye Movement Sleep in Mice through GABAA-benzodiazepine Receptors.
Molecular pharmacology.
2016 Nov; 90(5):530-539. doi:
10.1124/mol.116.105080. [PMID: 27573669] - ". Drugs for Insomnia.
The Medical letter on drugs and therapeutics.
2015 Jul; 57(1472):95-8. doi:
". [PMID: 26147892] - Zhenhua Jin, Sojin Kim, Suengmok Cho, In-Ho Kim, Daeseok Han, Young-Ho Jin. Potentiating effect of glabridin on GABAA receptor-mediated responses in dorsal raphe neurons.
Planta medica.
2013 Oct; 79(15):1408-12. doi:
10.1055/s-0033-1350698. [PMID: 23975867] - Niteeka Maroo, Avijit Hazra, Tapas Das. Efficacy and safety of a polyherbal sedative-hypnotic formulation NSF-3 in primary insomnia in comparison to zolpidem: a randomized controlled trial.
Indian journal of pharmacology.
2013 Jan; 45(1):34-9. doi:
10.4103/0253-7613.106432. [PMID: 23543804] - Y Hojo, M Echizenya, T Ohkubo, T Shimizu. Drug interaction between St John's wort and zolpidem in healthy subjects.
Journal of clinical pharmacy and therapeutics.
2011 Dec; 36(6):711-5. doi:
10.1111/j.1365-2710.2010.01223.x. [PMID: 21058968] - Ping Liu, Xinrong He, Mei Guo. [Single and combining effects of Calculus Bovis and zolpidem on inhibitive neurotransmitter of rat striatum corpora].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2010 Apr; 35(7):904-7. doi:
10.4268/cjcmm20100723. [PMID: 20575397] - Anil Kumar, Richa Goyal. Possible GABAergic modulation in the protective effect of zolpidem in acute hypoxic stress-induced behavior alterations and oxidative damage.
Neurochemical research.
2008 Mar; 33(3):370-7. doi:
10.1007/s11064-007-9431-9. [PMID: 17768679] - Mahendra Bishnoi, Kanwaljit Chopra, Shrinivas K Kulkarni. Possible anti-oxidant and neuroprotective mechanisms of zolpidem in attenuating typical anti-psychotic-induced orofacial dyskinesia: a biochemical and neurochemical study.
Progress in neuro-psychopharmacology & biological psychiatry.
2007 Jun; 31(5):1130-8. doi:
10.1016/j.pnpbp.2007.04.007. [PMID: 17513028] - Guillermo García-Santos, Federico Herrera, Vanesa Martín, Jezabel Rodriguez-Blanco, Isaac Antolín, Felix Fernández-Marí, Carmen Rodriguez. Antioxidant activity and neuroprotective effects of zolpidem and several synthesis intermediates.
Free radical research.
2004 Dec; 38(12):1289-99. doi:
10.1080/10715760400017343. [PMID: 15763953] - Anil Kumar, S K Kulkarni. On the sleep promoting effects of BR-16A: interaction with GABAergic modulators.
Indian journal of experimental biology.
2004 May; 42(5):448-51. doi:
". [PMID: 15233467]