Codeine phosphate hemihydrate (BioDeep_00000858929)
代谢物信息卡片
Codeine phosphate hemihydrate
化学式: C36H50N2O15P2 (812.268629)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CN1CCC23C4C1CC5=C2C(=C(C=C5)OC)OC3C(C=C4)O.CN1CCC23C4C1CC5=C2C(=C(C=C5)OC)OC3C(C=C4)O.O.OP(=O)(O)O.OP(=O)(O)O
InChI: /m00.../s1
描述信息
D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D009294 - Narcotics
D002492 - Central Nervous System Depressants > D009294 - Narcotics > D053610 - Opiate Alkaloids
C78272 - Agent Affecting Nervous System > C67413 - Opioid Receptor Agonist > C1657 - Opiate
D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents
D019141 - Respiratory System Agents > D000996 - Antitussive Agents
D002491 - Central Nervous System Agents > D000700 - Analgesics
同义名列表
1 个代谢物同义名
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
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The Cochrane database of systematic reviews.
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Open biology.
2023 May; 13(5):220355. doi:
10.1098/rsob.220355. [PMID: 37132222] - Vedrana Bulat, Robert Likic, Nives Pondeljak, Marija Delas Azdajic. Pholcodine-induced Stevens-Johnson syndrome in a patient with COVID-19.
Postgraduate medical journal.
2022 07; 98(1161):499-500. doi:
10.1136/postgradmedj-2021-139892. [PMID: 33879549] - Heba Elmansi, Fathalla Belal, Galal Magdy. Determination of pholcodine alone or in combination with ephedrine in human plasma using fluorescence spectroscopy.
Scientific reports.
2022 06; 12(1):9372. doi:
10.1038/s41598-022-13194-1. [PMID: 35672340] - Vlad Radoi, Gerd Jakobsson, Vinko Palada, Andrej Nikosjkov, Henrik Druid, Lars Terenius, Eva Kosek, Vladana Vukojević. Non-Peptide Opioids Differ in Effects on Mu-Opioid (MOP) and Serotonin 1A (5-HT1A) Receptors Heterodimerization and Cellular Effectors (Ca2+, ERK1/2 and p38) Activation.
Molecules (Basel, Switzerland).
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Journal of ethnopharmacology.
2022 Feb; 284(?):114754. doi:
10.1016/j.jep.2021.114754. [PMID: 34662663] - Ida Kuhlmann, Amanda Nøddebo Nyrup, Tore Bjerregaard Stage, Mette Marie Hougaard Christensen, Troels Korshøj Bergmann, Per Damkier, Flemming Nielsen, Kurt Højlund, Kim Brøsen. Oral and intravenous pharmacokinetics of metformin with and without oral codeine intake in healthy subjects: A cross-over study.
Clinical and translational science.
2021 11; 14(6):2408-2419. doi:
10.1111/cts.13107. [PMID: 34268884] - Marie Epain, Nathalie Cartiser, Fabien Bévalot, Laurent Fanton. Toxicological detection of pholcodine in blood, urine and hair in three cases of fatal intoxication.
Forensic science international.
2021 Oct; 327(?):110975. doi:
10.1016/j.forsciint.2021.110975. [PMID: 34478894] - R E Akhigbe, L O Ajayi, A F Ajayi. Codeine exerts cardiorenal injury via upregulation of adenine deaminase/xanthine oxidase and caspase 3 signaling.
Life sciences.
2021 May; 273(?):118717. doi:
10.1016/j.lfs.2020.118717. [PMID: 33159958] - Joht Singh Chandan, Dawit Tefra Zemedikun, Rasiah Thayakaran, Nathan Byne, Samir Dhalla, Dionisio Acosta-Mena, Krishna M Gokhale, Tom Thomas, Christopher Sainsbury, Anuradhaa Subramanian, Jennifer Cooper, Astha Anand, Kelvin O Okoth, Jingya Wang, Nicola J Adderley, Thomas Taverner, Alastair K Denniston, Janet Lord, G Neil Thomas, Christopher D Buckley, Karim Raza, Neeraj Bhala, Krishnarajah Nirantharakumar, Shamil Haroon. Nonsteroidal Antiinflammatory Drugs and Susceptibility to COVID-19.
Arthritis & rheumatology (Hoboken, N.J.).
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2021 Apr; 59(5):482-489. doi:
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Journal of analytical toxicology.
2021 Mar; 45(3):215-225. doi:
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2021 Jan; 59(2):140-147. doi:
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Veterinary anaesthesia and analgesia.
2020 Sep; 47(5):694-704. doi:
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American journal of veterinary research.
2020 Aug; 81(8):627-634. doi:
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Journal of pharmaceutical and biomedical analysis.
2020 Jun; 185(?):113247. doi:
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Journal of pharmaceutical and biomedical analysis.
2020 May; 184(?):113175. doi:
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Journal of agricultural and food chemistry.
2020 May; 68(18):5241-5248. doi:
10.1021/acs.jafc.0c01681. [PMID: 32302121] - Ahmed I Al-Asmari. Postmortem Fluid Concentrations of Heroin Biomarkers and Their Metabolites.
Journal of forensic sciences.
2020 Mar; 65(2):570-579. doi:
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Andrology.
2020 03; 8(2):509-515. doi:
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2020 Feb; 25(4):. doi:
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Analytical and bioanalytical chemistry.
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Bulletin of environmental contamination and toxicology.
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Plant physiology.
2019 11; 181(3):916-933. doi:
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Biopharmaceutics & drug disposition.
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Journal of separation science.
2019 Oct; 42(19):3126-3133. doi:
10.1002/jssc.201900276. [PMID: 31347772] - Chetan Shende, Carl Brouillette, Stuart Farquharson. Detection of codeine and fentanyl in saliva, blood plasma and whole blood in 5-minutes using a SERS flow-separation strip.
The Analyst.
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Cellular and molecular neurobiology.
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Medicina (Kaunas, Lithuania).
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Drug and alcohol dependence.
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Nature chemical biology.
2019 04; 15(4):384-390. doi:
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Drug research.
2019 Apr; 69(4):207-210. doi:
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Drug testing and analysis.
2019 Mar; 11(3):536-540. doi:
10.1002/dta.2559. [PMID: 30569568] - Amir Nili-Ahmadabadi, Zahra Borzouee, Davoud Ahmadimoghaddam, Farzin Firozian, Dara Dastan. The occurrence of acetaminophen/codeine as an adulterant in herbal analgesic supplements in Hamadan, Iran: A pilot study.
Complementary therapies in medicine.
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Clinical chemistry.
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Clinical chemistry.
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Nephrology (Carlton, Vic.).
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Forensic science, medicine, and pathology.
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Drug testing and analysis.
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The Analyst.
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Therapeutic drug monitoring.
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Biopharmaceutics & drug disposition.
2017 Jan; 38(1):50-74. doi:
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Materials science & engineering. C, Materials for biological applications.
2016 Dec; 69(?):1-11. doi:
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Journal of veterinary pharmacology and therapeutics.
2016 Oct; 39(5):514-7. doi:
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Journal of analytical toxicology.
2016 Oct; 40(8):601-607. doi:
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Forensic science, medicine, and pathology.
2016 Sep; 12(3):243-7. doi:
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Environment international.
2016 Sep; 94(?):307-314. doi:
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Analytical and bioanalytical chemistry.
2016 Sep; 408(23):6283-94. doi:
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The journal of physical chemistry. B.
2016 08; 120(33):8606-16. doi:
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International journal of pharmaceutics.
2016 Jul; 509(1-2):219-228. doi:
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Journal of analytical toxicology.
2016 Jun; 40(5):330-7. doi:
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Journal of chemical information and modeling.
2016 04; 56(4):721-33. doi:
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Journal of chromatographic science.
2016 Apr; 54(4):569-73. doi:
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Journal of analytical toxicology.
2016 Mar; 40(2):148-52. doi:
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Nature communications.
2016 Feb; 7(?):10390. doi:
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Analytical chemistry.
2016 Jan; 88(2):1259-65. doi:
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Journal of pharmaceutical and biomedical analysis.
2015 Oct; 114(?):105-12. doi:
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Journal of analytical toxicology.
2015 Oct; 39(8):655-61. doi:
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Clinical pharmacokinetics.
2015 Oct; 54(10):1083-90. doi:
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Monoclonal antibodies in immunodiagnosis and immunotherapy.
2015 Aug; 34(4):270-4. doi:
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International journal of biological macromolecules.
2015 Aug; 79(?):388-91. doi:
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Drug testing and analysis.
2015 Jul; 7(7):586-91. doi:
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Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
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Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.
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Journal of analytical toxicology.
2015 Jun; 39(5):407-10. doi:
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The Journal of the Association of Physicians of India.
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Molecules (Basel, Switzerland).
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Zhongguo zhen jiu = Chinese acupuncture & moxibustion.
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Journal of pain & palliative care pharmacotherapy.
2015 Mar; 29(1):4-15. doi:
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Talanta.
2015 Mar; 134(?):745-753. doi:
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Analytical and bioanalytical chemistry.
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Advances in experimental medicine and biology.
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Journal of analytical toxicology.
2015 Jan; 39(1):24-8. doi:
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