Mupirocin calcium hydrate (BioDeep_00000858920)
代谢物信息卡片
Mupirocin calcium hydrate
化学式: C52H90CaO20 (1074.5651)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(C1C(O1)CC2COC(C(C2O)O)CC(=CC(=O)OCCCCCCCCC(=O)[O-])C)C(C)O.CC(C1C(O1)CC2COC(C(C2O)O)CC(=CC(=O)OCCCCCCCCC(=O)[O-])C)C(C)O.O.O.[Ca+2]
InChI: +2
描述信息
D004791 - Enzyme Inhibitors > D011500 - Protein Synthesis Inhibitors
C254 - Anti-Infective Agent > C28394 - Topical Anti-Infective Agent
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents
同义名列表
1 个代谢物同义名
数据库引用编号
5 个数据库交叉引用编号
- ChEBI: CHEBI:34858
- KEGGdrug: D02195
- PubChem: 5282317
- ChEMBL: CHEMBL3989715
- MeSH: Mupirocin
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Yaya Qiao, Meng Su, Huifang Zhao, Huanle Liu, Chenxi Wang, Xintong Dai, Lingling Liu, Guangju Liu, Huanran Sun, Mingming Sun, Jiyan Wang, Zhen Li, Jun Fan, Quan Zhang, Chunshen Li, Fangmin Situ, Jun Xue, Zhenghu Jia, Chunze Zhang, Shuai Zhang, Changliang Shan. Targeting FTO induces colorectal cancer ferroptotic cell death by decreasing SLC7A11/GPX4 expression.
Journal of experimental & clinical cancer research : CR.
2024 Apr; 43(1):108. doi:
10.1186/s13046-024-03032-9. [PMID: 38600610] - Hai Bang Pan, Yan Cui, Zhi Hang Wu, Ying Meng, Tian Ming Wang, Qi Fu, Qian Chen, Quan Xin Chen, Bo Wang. Effect of Different Local Antibiotic Regimens on Prevention of Postoperative Infection in Clean Surgical Wounds: A Systematic Review and Network Meta-analysis.
Advances in skin & wound care.
2024 Apr; 37(4):216-223. doi:
10.1097/asw.0000000000000094. [PMID: 38353666] - Priyanka V Patil, Mala D Menon, Aparna D Palshetkar, Namita D Desai. Topical delivery of mupirocin calcium nanostructured lipid carriers using a full-thickness excision wound healing model.
Journal of wound care.
2023 May; 32(Sup5a):lxiii-lxxiv. doi:
10.12968/jowc.2023.32.sup5a.lxiii. [PMID: 37094978] - Lila Moghiseh, Monir Nobahar, Raheb Ghorbani, Shiva Sirafian. The impact of Propolis on catheter exit site infection and peritonitis in peritoneal Dialysis patients: a clinical trial.
BMC nephrology.
2022 12; 23(1):408. doi:
10.1186/s12882-022-03036-7. [PMID: 36564743] - Zhiling Cai, Zitong Mo, Shiqian Zheng, Shihua Lan, Shengjun Xie, Jinghui Lu, Chunping Tang, Zhibin Shen. Flavaspidic acid BB combined with mupirocin improves its anti-bacterial and anti-biofilm activities against Staphylococcus epidermidis.
BMC microbiology.
2022 07; 22(1):179. doi:
10.1186/s12866-022-02578-y. [PMID: 35840879] - Nannan Zhang, Jin Wu, Siping Zhang, Maoran Yuan, Hang Xu, Jie Li, Pingping Zhang, Mingzhu Wang, Megan L Kempher, Xuanyu Tao, Li-Qun Zhang, Honghua Ge, Yong-Xing He. Molecular basis for coordinating secondary metabolite production by bacterial and plant signaling molecules.
The Journal of biological chemistry.
2022 06; 298(6):102027. doi:
10.1016/j.jbc.2022.102027. [PMID: 35568198] - Mansi Budhiraja, Sobiya Zafar, Sohail Akhter, Majed Alrobaian, Md Abdur Rashid, Md Abul Barkat, Sarwar Beg, Farhan J Ahmad. Mupirocin-Loaded Chitosan Microspheres Embedded in Piper betle Extract Containing Collagen Scaffold Accelerate Wound Healing Activity.
AAPS PharmSciTech.
2022 Feb; 23(3):77. doi:
10.1208/s12249-022-02233-9. [PMID: 35194725] - Zeynep Ay Şenyiğit, Nesrin Coşkunmeriç, Emre Şefik Çağlar, İsmail Öztürk, Evren Atlıhan Gündoğdu, Panoraia I Siafaka, Neslihan Üstündağ Okur. Chitosan-bovine serum albumin-Carbopol 940 nanogels for mupirocin dermal delivery: ex-vivo permeation and evaluation of cellular binding capacity via radiolabeling.
Pharmaceutical development and technology.
2021 Oct; 26(8):852-866. doi:
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Scientific reports.
2021 05; 11(1):10935. doi:
10.1038/s41598-021-90360-x. [PMID: 34035383] - Alok Pratap Singh, Satish Kumar Sharma, Praveen Kumar Gaur, Dinesh Kumar Gupta. Fabrication of Mupirocin-Loaded Nanostructured Lipid Carrier and Its In Vitro Characterization.
Assay and drug development technologies.
2021 May; 19(4):216-225. doi:
10.1089/adt.2020.1070. [PMID: 33781090] - Victoria S Lee, Paul S Pottinger, Greg E Davis. Tolerability and effectiveness of povidone-iodine or mupirocin versus saline sinus irrigations for chronic rhinosinusitis.
American journal of otolaryngology.
2020 Sep; 41(5):102604. doi:
10.1016/j.amjoto.2020.102604. [PMID: 32563787] - Morteza Najaf Zadeh Gharaboghaz, Mohammad Reza Farahpour, Shahram Saghaie. Topical co-administration of Teucrium polium hydroethanolic extract and Aloe vera gel triggered wound healing by accelerating cell proliferation in diabetic mouse model.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2020 Jul; 127(?):110189. doi:
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Journal of global antimicrobial resistance.
2020 06; 21(?):171-180. doi:
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Surgical infections.
2020 May; 21(4):323-331. doi:
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Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation.
2020 04; 18(2):153-156. doi:
10.6002/ect.2018.0341. [PMID: 31266440] - Natalia Pettinelli, Saddys Rodríguez-Llamazares, Yousof Farrag, Rebeca Bouza, Luis Barral, Sandra Feijoo-Bandín, Francisca Lago. Poly(hydroxybutyrate-co-hydroxyvalerate) microparticles embedded in κ-carrageenan/locust bean gum hydrogel as a dual drug delivery carrier.
International journal of biological macromolecules.
2020 Mar; 146(?):110-118. doi:
10.1016/j.ijbiomac.2019.12.193. [PMID: 31881300] - Oliver Goldmann, Ahuva Cern, Mathias Müsken, Manfred Rohde, William Weiss, Yechezkel Barenholz, Eva Medina. Liposomal mupirocin holds promise for systemic treatment of invasive Staphylococcus aureus infections.
Journal of controlled release : official journal of the Controlled Release Society.
2019 12; 316(?):292-301. doi:
10.1016/j.jconrel.2019.11.007. [PMID: 31715276] - Surapon Nochaiwong, Chidchanok Ruengorn, Kajohnsak Noppakun, Setthapon Panyathong, Phongsak Dandecha, Manish M Sood, Chalermpong Saenjum, Ratanaporn Awiphan, Sasithorn Sirilun, Pajaree Mongkhon, Wilaiwan Chongruksut, Kednapa Thavorn. Comparative Effectiveness of Local Application of Chlorhexidine Gluconate, Mupirocin Ointment, and Normal Saline for the Prevention of Peritoneal Dialysis-related Infections (COSMO-PD Trial): a multicenter randomized, double-blind, controlled protocol.
Trials.
2019 Dec; 20(1):754. doi:
10.1186/s13063-019-3953-8. [PMID: 31856900] - Khent P Alcantara, Mohd Hanif Zulfakar, Agnes L Castillo. Development, characterization and pharmacokinetics of mupirocin-loaded nanostructured lipid carriers (NLCs) for intravascular administration.
International journal of pharmaceutics.
2019 Nov; 571(?):118705. doi:
10.1016/j.ijpharm.2019.118705. [PMID: 31536765] - Charlotta Magnusson, Marc Stegger, Bengt Hellmark, Bianca Stenmark, Bo Söderquist. Staphylococcus aureus isolates from nares of orthopaedic patients in Sweden are mupirocin susceptible.
Infectious diseases (London, England).
2019 06; 51(6):475-478. doi:
10.1080/23744235.2019.1593500. [PMID: 30985251] - Oleg N Reva, Sunelle Rademan, Michelle H Visagie, Maphuti T Lebelo, Mokgadi V Gwangwa, Vitalii V Klochko, Anna M Joubert, Namrita Lall. Comparison of structures and cytotoxicity of mupirocin and batumin against melanoma and several other cancer cell lines.
Future medicinal chemistry.
2019 04; 11(7):677-691. doi:
10.4155/fmc-2018-0333. [PMID: 30947530] - Xiaofang Lv, Rui Feng, Jingbo Zhai. A combination of mupirocin and acidic fibroblast growth factor for nipple fissure and nipple pain in breastfeeding women: protocol for a randomised, double-blind, controlled trial.
BMJ open.
2019 03; 9(3):e025526. doi:
10.1136/bmjopen-2018-025526. [PMID: 30918032] - Theo O Dare, Andrew W Nicholls, Peter G Mantle. Monic acid A: a biomarker in clinical intra-nasal mupirocin medication for MRSA decolonisation.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals.
2019 Mar; 24(2):131-133. doi:
10.1080/1354750x.2018.1514657. [PMID: 30126316] - Johannes Arp, Sebastian Götze, Ruchira Mukherji, Derek J Mattern, María García-Altares, Martin Klapper, Debra A Brock, Axel A Brakhage, Joan E Strassmann, David C Queller, Bettina Bardl, Karsten Willing, Gundela Peschel, Pierre Stallforth. Synergistic activity of cosecreted natural products from amoebae-associated bacteria.
Proceedings of the National Academy of Sciences of the United States of America.
2018 04; 115(15):3758-3763. doi:
10.1073/pnas.1721790115. [PMID: 29592954] - Jian Huang, Jinhua Huang, Yaping Xiang, Lihua Gao, Yizhi Pan, Jianyun Lu. [Topical ozone therapy: An innovative solution to patients with herpes zoster].
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences.
2018 Feb; 43(2):168-172. doi:
10.11817/j.issn.1672-7347.2018.02.011. [PMID: 29559601] - Kordo Saeed, Ian Gould, Silvano Esposito, Nusreen Ahmad-Saeed, Salman Shaheer Ahmed, Emine Alp, Abhijit M Bal, Matteo Bassetti, Eric Bonnet, Monica Chan, Geoffrey Coombs, Stephanie J Dancer, Michael Z David, Giuseppe De Simone, Matthew Dryden, Luca Guardabassi, Leif G Hanitsch, Karolin Hijazi, Renate Krüger, Andie Lee, Rasmus Leistner, Pasquale Pagliano, Elda Righi, Sylke Schneider-Burrus, Robert Leo Skov, Pierre Tattevin, Willem Van Wamel, Margreet C Vos, Andreas Voss. Panton-Valentine leukocidin-positive Staphylococcus aureus: a position statement from the International Society of Chemotherapy.
International journal of antimicrobial agents.
2018 Jan; 51(1):16-25. doi:
10.1016/j.ijantimicag.2017.11.002. [PMID: 29174420] - Aleksandra Budzyńska, Sylwia Różalska, Beata Sadowska, Barbara Różalska. Candida albicans/Staphylococcus aureus Dual-Species Biofilm as a Target for the Combination of Essential Oils and Fluconazole or Mupirocin.
Mycopathologia.
2017 Dec; 182(11-12):989-995. doi:
10.1007/s11046-017-0192-y. [PMID: 28823093] - Lei Zhang, Sunil V Badve, Elaine M Pascoe, Elaine Beller, Alan Cass, Carolyn Clark, Janak de Zoysa, Nicole M Isbel, Xusheng Liu, Steven McTaggart, Alicia T Morrish, Geoffrey Playford, Anish Scaria, Paul Snelling, Liza A Vergara, Carmel M Hawley, David W Johnson. Representativeness of Honeypot Trial Participants to Australasian PD Patients.
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis.
2017 Sep; 37(5):516-522. doi:
10.3747/pdi.2016.00065. [PMID: 27935534] - Xiaowen Su, Xinguang Liu, Shouyu Wang, Bin Li, Taowen Pan, Dingrui Liu, Fei Wang, Yunpeng Diao, Kun Li. Wound-healing promoting effect of total tannins from Entada phaseoloides (L.) Merr. in rats.
Burns : journal of the International Society for Burn Injuries.
2017 Jun; 43(4):830-838. doi:
10.1016/j.burns.2016.10.010. [PMID: 28040363] - Htay Htay, David W Johnson, Sin Yan Wu, Elizabeth Ley Oei, Marjorie Wai Yin Foo, Jason Chon Jun Choo. Comparison of Topical Chlorhexidine and Mupirocin for the Prevention of Exit-Site Infection in Incident Peritoneal Dialysis Patients.
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis.
2017 May; 37(3):266-272. doi:
10.3747/pdi.2016.00257. [PMID: 28183858] - Martin Wilkie. Improving the Impact of Peritoneal Dialysis Research.
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis.
2017 May; 37(3):245-246. doi:
10.3747/pdi.2017.00001. [PMID: 28512160] - Denise Campbell, David W Mudge, Jonathan C Craig, David W Johnson, Allison Tong, Giovanni Fm Strippoli. Antimicrobial agents for preventing peritonitis in peritoneal dialysis patients.
The Cochrane database of systematic reviews.
2017 04; 4(?):CD004679. doi:
10.1002/14651858.cd004679.pub3. [PMID: 28390069] - Ping-Nam Wong, Gensy M W Tong, Yuk-Yi Wong, Kin-Yee Lo, Shuk-Fan Chan, Man-Wai Lo, Kwok-Chi Lo, Lo-Yi Ho, Cindy W S Tse, Siu-Ka Mak, Andrew K M Wong. Alternating Mupirocin/Gentamicin is Associated with Increased Risk of Fungal Peritonitis as Compared with Gentamicin Alone - Results of a Randomized Open-Label Controlled Trial.
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis.
2016 May; 36(3):340-6. doi:
10.3747/pdi.2015.00237. [PMID: 27044796] - J Novakova, E Vlkova, H Salmonova, R Pechar, V Rada, L Kokoska. Anticlostridial agent 8-hydroxyquinoline improves the isolation of faecal bifidobacteria on modified Wilkins-Chalgren agar with mupirocin.
Letters in applied microbiology.
2016 Apr; 62(4):330-5. doi:
10.1111/lam.12552. [PMID: 26849418] - Susan S Huang, Edward Septimus, Mary K Hayden, Ken Kleinman, Jessica Sturtevant, Taliser R Avery, Julia Moody, Jason Hickok, Julie Lankiewicz, Adrijana Gombosev, Rebecca E Kaganov, Katherine Haffenreffer, John A Jernigan, Jonathan B Perlin, Richard Platt, Robert A Weinstein. Effect of body surface decolonisation on bacteriuria and candiduria in intensive care units: an analysis of a cluster-randomised trial.
The Lancet. Infectious diseases.
2016 Jan; 16(1):70-79. doi:
10.1016/s1473-3099(15)00238-8. [PMID: 26631833] - S Murugesan, U Singh, N Perumal, V Ramanathan, P Krishnan. High level mupirocin resistance among CoNS from nasal carriers of End stage renal disease patients and hospital personnel from tertiary care centre, Chennai.
Indian journal of medical microbiology.
2016 Jan; 34(1):114-5. doi:
10.4103/0255-0857.167672. [PMID: 26776137] - Shigeki Toma, Takahiro Shinzato, Kunihiro Hayakawa. Access-Related Infections Involving the Buttonhole Technique.
Blood purification.
2016; 41(4):306-12. doi:
10.1159/000443781. [PMID: 26820709] - Lei Zhang, Sunil V Badve, Elaine M Pascoe, Elaine Beller, Alan Cass, Carolyn Clark, Janak de Zoysa, Nicole M Isbel, Steven McTaggart, Alicia T Morrish, E Geoffrey Playford, Anish Scaria, Paul Snelling, Liza A Vergara, Carmel M Hawley, David W Johnson. The Effect of Exit-Site Antibacterial Honey Versus Nasal Mupirocin Prophylaxis on the Microbiology and Outcomes of Peritoneal Dialysis-Associated Peritonitis and Exit-Site Infections: A Sub-Study of the Honeypot Trial.
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis.
2015 Dec; 35(7):712-21. doi:
10.3747/pdi.2014.00206. [PMID: 26224790] - Bryce D Beutler, Philip R Cohen. Verruciform Genital-Associated (Vegas) Xanthoma: report of a patient with verruciform xanthoma of the scrotum and literature review.
Dermatology online journal.
2015 Aug; 21(8):. doi:
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Diagnostic microbiology and infectious disease.
2015 Aug; 82(4):278-83. doi:
10.1016/j.diagmicrobio.2015.03.023. [PMID: 26008124] - Arnav Agarwal, Gihad Nesrallah. Long-Term Safety of Buttonhole Cannulation and Efficacy of Mupirocin Prophylaxis.
Contributions to nephrology.
2015; 186(?):64-70. doi:
10.1159/000431162. [PMID: 26283561] - Cibele Grothe, Mônica Taminato, Angélica Belasco, Ricardo Sesso, Dulce Barbosa. Screening and treatment for Staphylococcus aureus in patients undergoing hemodialysis: a systematic review and meta-analysis.
BMC nephrology.
2014 Dec; 15(?):202. doi:
10.1186/1471-2369-15-202. [PMID: 25519998] - Radko Pechar, Vojtech Rada, Lucia Parafati, Sarka Musilova, Vera Bunesova, Eva Vlkova, Jiri Killer, Jakub Mrazek, Vladimir Kmet, Roman Svejstil. Mupirocin-mucin agar for selective enumeration of Bifidobacterium bifidum.
International journal of food microbiology.
2014 Nov; 191(?):32-5. doi:
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Journal of pharmaceutical sciences.
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Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals.
2011 Aug; 16(5):422-5. doi:
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Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis.
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Clinical journal of the American Society of Nephrology : CJASN.
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Regulatory toxicology and pharmacology : RTP.
2009 Oct; 55(1):28-32. doi:
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The Journal of infectious diseases.
2009 Jun; 199(12):1820-6. doi:
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Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia.
2008 Sep; 19(5):737-45. doi:
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