cefsulodin sodium (BioDeep_00000858910)

   


代谢物信息卡片


cefsulodin sodium

化学式: C22H19N4NaO8S2 (554.0541974)
中文名称: 头孢磺啶钠盐水合物
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1C(=C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)S(=O)(=O)[O-])C(=O)[O-])C[N+]4=CC=C(C=C4)C(=O)N.[Na+]
InChI: /q

描述信息

J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01D - Other beta-lactam antibacterials > J01DD - Third-generation cephalosporins
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D002511 - Cephalosporins
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D047090 - beta-Lactams
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D007769 - Lactams
C254 - Anti-Infective Agent > C258 - Antibiotic > C260 - Beta-Lactam Antibiotic

同义名列表

2 个代谢物同义名

cefsulodin sodium; Cefsulodin sodium



数据库引用编号

9 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

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PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

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PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Giuseppe Deganutti, Filippo Prischi, Christopher A Reynolds. Supervised molecular dynamics for exploring the druggability of the SARS-CoV-2 spike protein. Journal of computer-aided molecular design. 2021 02; 35(2):195-207. doi: 10.1007/s10822-020-00356-4. [PMID: 33103220]
  • María González, María Jose Gude, Cristina Seral, Maria Pilar Abad, Sonia Algarate, F Javier Castillo. [Comparasion of two methods for recovery of Aeromonas spp. in feces from agar CIN (Cefsulodin-Irgasan-Novobiocin)]. Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia. 2010 Dec; 23(4):217-8. doi: . [PMID: 21191564]
  • Souad Kalai, Wafa Jouaihia, Faouzia Mahjoubi, Rafiaa Ghozzi, Lamia Thabet, Saida Ben Rejeb, Adnène Hammami, Amel Kechrid, Assia Ben Hassen. [Pseudomonas aeruginosa: a multicentric study of antibiotic resistance (1999-2000)]. La Tunisie medicale. 2004 Dec; 82(12):1070-4. doi: . [PMID: 15822507]
  • G Foster, G F Hopkins, G J Gunn, H E Ternent, F Thomson-Carter, H I Knight, D J L Graham, V Edge, B A Synge. A comparison of two pre-enrichment media prior to immunomagnetic separation for the isolation of E. coli O157 from bovine faeces. Journal of applied microbiology. 2003; 95(1):155-9. doi: 10.1046/j.1365-2672.2003.01955.x. [PMID: 12807466]
  • M A Hornitzky, K A Bettelheim, S P Djordjevic. The detection of Shiga toxin-producing Escherichia coli in diagnostic bovine faecal samples using vancomycin-cefixime-cefsulodin blood agar and PCR. FEMS microbiology letters. 2001 Apr; 198(1):17-22. doi: 10.1111/j.1574-6968.2001.tb10613.x. [PMID: 11325548]
  • A Lehmacher, H Meier, S Aleksic, J Bockemühl. Detection of hemolysin variants of Shiga toxin-producing Escherichia coli by PCR and culture on vancomycin-cefixime-cefsulodin blood agar. Applied and environmental microbiology. 1998 Jul; 64(7):2449-53. doi: 10.1128/aem.64.7.2449-2453.1998. [PMID: 9647814]
  • B Nerli, B Farruggia, G Picó. A comparative study of the binding characteristics of ceftriaxone, cefoperazone and cefsulodin to human serum albumin. Biochemistry and molecular biology international. 1996 Nov; 40(4):823-31. doi: 10.1080/15216549600201433. [PMID: 8950041]
  • K Ishibashi, O Yamaguchi, Y Shiraiwa, M Ogihara, S Shigeta. Combination therapy of Pseudomonas aeruginosa pyelonephritis in neutropenic mice with human antilipopolysaccharide monoclonal antibody and cefsulodin. The Journal of urology. 1996 Jun; 155(6):2094-7. doi: . [PMID: 8618343]
  • A Radouane, F Péhourcq, G Tramu, E E Creppy, B Bannwarth. Influence of lipophilicity on the diffusion of cephalosporins into the cerebrospinal fluid. Fundamental & clinical pharmacology. 1996; 10(3):309-13. doi: 10.1111/j.1472-8206.1996.tb00311.x. [PMID: 8836706]
  • J Reina, A Serra, N Borrell. [Efficacy of cefsulodin -irgasan-novobiocin agar media in the isolation of Aeromonas mesophiles from feces]. Enfermedades infecciosas y microbiologia clinica. 1993 Feb; 11(2):114-6. doi: NULL. [PMID: 8481436]
  • J Tommassen, P Vermeij, M Struyvé, R Benz, J T Poolman. Isolation of Neisseria meningitidis mutants deficient in class 1 (porA) and class 3 (porB) outer membrane proteins. Infection and immunity. 1990 May; 58(5):1355-9. doi: 10.1128/iai.58.5.1355-1359.1990. [PMID: 2157669]
  • A Hedman, G Alván, B Strandvik, A Arvidsson. Increased renal clearance of cefsulodin due to higher glomerular filtration rate in cystic fibrosis. Clinical pharmacokinetics. 1990 Feb; 18(2):168-75. doi: 10.2165/00003088-199018020-00006. [PMID: 2180614]
  • N Cho, K Fukunaga, K Kunii. [Pharmacokinetic studies on cefsulodin in perinatal period]. The Japanese journal of antibiotics. 1989 Dec; 42(12):2735-42. doi: . [PMID: 2515321]
  • T Motohiro, M Aramaki, A Kawakami, K Tanaka, T Koga, Y Shimada, S Tomita, Y Sakata, T Fujimoto, T Nishiyama. [Fundamental and clinical studies of cefsulodin in the neonates and premature infants]. The Japanese journal of antibiotics. 1989 Dec; 42(12):2720-34. doi: . [PMID: 2614923]
  • K Fujita, K Murono, H Sakata, H Yoshioka. [Clinical and pharmacokinetic evaluation of cefsulodin in neonates and young infants]. The Japanese journal of antibiotics. 1989 Dec; 42(12):2709-13. doi: . [PMID: 2515319]
  • S Iwata, Y Sato, M Tojo, Y Kusumoto, H Shiro, H Akita, S Nanri, T Oikawa, M Osano, S Kusano. [Pharmacokinetics and clinical studies on cefsulodin in neonates]. The Japanese journal of antibiotics. 1989 Dec; 42(12):2714-9. doi: . [PMID: 2515320]
  • K Bauer, M Struyvé, D Bosch, R Benz, J Tommassen. One single lysine residue is responsible for the special interaction between polyphosphate and the outer membrane porin PhoE of Escherichia coli. The Journal of biological chemistry. 1989 Oct; 264(28):16393-8. doi: 10.1016/s0021-9258(19)84719-1. [PMID: 2476443]
  • R Brouard, T N Tozer, H Merdjan, A Guillemin, A Baumelou. Transperitoneal movement and pharmacokinetics of cefotiam and cefsulodin in patients on continuous ambulatory peritoneal dialysis. Clinical nephrology. 1988 Oct; 30(4):197-206. doi: . [PMID: 3214965]
  • H Washida, H Sakagami, H Watanabe, S Sasaki. [Pharmacokinetic study of cefsulodin in patients with kidney dysfunction]. The Japanese journal of antibiotics. 1988 Sep; 41(9):1272-8. doi: NULL. [PMID: 3241325]
  • G Satta, G Cornaglia, P Canepari, R Pompei. Evaluation of bactericidal activity of cefotaxime and other beta-lactams by a novel method. Drugs. 1988; 35 Suppl 2(?):35-40. doi: 10.2165/00003495-198800352-00009. [PMID: 3293978]
  • S Asari, M Horikawa, H Tsukamoto, K Kouda, C Hayashi, K Miyai. [Susceptibility of clinical isolates to aztreonam]. The Japanese journal of antibiotics. 1987 Jul; 40(7):1317-31. doi: . [PMID: 3479624]
  • D B Wright. Cefsulodin. Drug intelligence & clinical pharmacy. 1986 Nov; 20(11):845-9. doi: 10.1177/106002808602001104. [PMID: 3536385]
  • H Michalsen, T Bergan, R Solberg. Pharmacokinetic evaluation of cefsulodin in children with and without cystic fibrosis treated for infectious diseases. Methods and findings in experimental and clinical pharmacology. 1986 Nov; 8(11):685-7. doi: . [PMID: 3807469]
  • J Z Montgomerie, J W Morrow, H N Canawati, D S Gilmore, I E Graham, M Z Ibraham. Cefsulodin in treatment of Pseudomonas urinary tract infection in patients with spinal cord injury. Comparison with aminoglycosides. Urology. 1986 Nov; 28(5):446-50. doi: 10.1016/0090-4295(86)90087-7. [PMID: 3787915]
  • T Nakamura, I Hashimoto, Y Sawada, J Mikami, M Yoshimoto, H Nishindai, Y Nakanishi. [Cefsulodin concentration in exudates from drainage of patients with acute peritonitis following intravenous administration]. The Japanese journal of antibiotics. 1986 Sep; 39(9):2355-66. doi: . [PMID: 3099029]
  • H Fukushima, M Gomyoda. Growth of Yersinia pseudotuberculosis and Yersinia enterocolitica biotype 3B serotype O3 inhibited on cefsulodin-Irgasan-novobiocin agar. Journal of clinical microbiology. 1986 Jul; 24(1):116-20. doi: 10.1128/jcm.24.1.116-120.1986. [PMID: 3722357]
  • A Tormo, J A Ayala, M A de Pedro, M Aldea, M Vicente. Interaction of FtsA and PBP3 proteins in the Escherichia coli septum. Journal of bacteriology. 1986 Jun; 166(3):985-92. doi: 10.1128/jb.166.3.985-992.1986. [PMID: 3011758]
  • P Drigues, M Labrousse, T Combes, C Mas, G Roche. [Bactericidal activity of cefpiramide on P. aeruginosa using an in vitro pharmacokinetic simulation model]. Pathologie-biologie. 1986 May; 34(5):431-5. doi: NULL. [PMID: 3095776]
  • E Rubinstein, Z Mark, Y Samra, M Alkan, S Berger. In vitro activity of ciprofloxacin compared with other agents against recent hospital isolates. Chemioterapia : international journal of the Mediterranean Society of Chemotherapy. 1986 Apr; 5(2):75-82. doi: . [PMID: 2939966]
  • R Altorfer, M Altwegg, J Zollinger-Iten, A von Graevenitz. Growth of Aeromonas spp. on cefsulodin-Irgasan-novobiocin agar selective for Yersinia enterocolitica. Journal of clinical microbiology. 1985 Oct; 22(4):478-80. doi: 10.1128/jcm.22.4.478-480.1985. [PMID: 4077959]
  • F Dromer, A Contrepois, N Brion, C Klein, C Carbon. Effects of urinary pH on renal interactions between probenecid and cefsulodin in rabbits. Antimicrobial agents and chemotherapy. 1985 Apr; 27(4):660-2. doi: 10.1128/aac.27.4.660. [PMID: 4004198]
  • B Völker, U Mester, N Mendel. [Intraocular penetration of systemically administered cephalosporins under steady-state conditions in animal experiments]. Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde. 1985; 191(1):29-34. doi: 10.1159/000309535. [PMID: 3861992]
  • Y Ikeda, T Higashijima, Y Oguchi, K Okumura, M Ozeki, A Okada. [Pharmacokinetic study of cefsulodin in children]. The Japanese journal of antibiotics. 1985 Jan; 38(1):145-54. doi: NULL. [PMID: 3989975]
  • H A Elder, I Roy. Treatment of urinary tract infections due to Pseudomonas aeruginosa with cefsulodin. Reviews of infectious diseases. 1984 Sep; 6 Suppl 3(?):S734-43. doi: 10.1093/clinids/6.supplement_3.s734. [PMID: 6443774]
  • T Nishimura, R Fujii. Clinical and pharmacokinetic study of parenteral administration of cefsulodin in pediatric patients in Japan. Reviews of infectious diseases. 1984 Sep; 6 Suppl 3(?):S751-8. doi: 10.1093/clinids/6.supplement_3.s751. [PMID: 6571339]
  • J B Lecaillon, M C Rouan, U Binswanger, J Guibert, J P Schoeller. Pharmacokinetics of cefotiam and cefsulodin after simultaneous administration to patients with impaired renal function. Antimicrobial agents and chemotherapy. 1984 Sep; 26(3):368-72. doi: 10.1128/aac.26.3.368. [PMID: 6095754]
  • L Nichols, S Gudmundsson, D G Maki. Experience with cefsulodin therapy for lower respiratory tract infections caused by Pseudomonas aeruginosa in adults without cystic fibrosis or granulocytopenia. Reviews of infectious diseases. 1984 Sep; 6 Suppl 3(?):S711-20. doi: 10.1093/clinids/6.supplement_3.s711. [PMID: 6443772]
  • T P Gibson, G R Granneman, J E Kallal, L T Sennello. Kinetics of cefsulodin in patients with renal impairment. Reviews of infectious diseases. 1984 Sep; 6 Suppl 3(?):S689-97. doi: 10.1093/clinids/6.supplement_3.s689. [PMID: 6571338]
  • B R Smith. Cefsulodin and ceftazidime, two antipseudomonal cephalosporins. Clinical pharmacy. 1984 Jul; 3(4):373-85. doi: . [PMID: 6380902]
  • M D Reed, R C Stern, T S Yamashita, I Ackers, C M Myers, J L Blumer. Single-dose pharmacokinetics of cefsulodin in patients with cystic fibrosis. Antimicrobial agents and chemotherapy. 1984 May; 25(5):579-81. doi: 10.1128/aac.25.5.579. [PMID: 6732226]
  • K P Fu, E F Kimble, H Zoganas, E A Konopka. Synergistic activity of cefsulodin combined with cefoxitin and sulbactam against Bacteroides species. The Journal of antimicrobial chemotherapy. 1984 Mar; 13(3):257-65. doi: 10.1093/jac/13.3.257. [PMID: 6327598]
  • E Bergogne-Berezin, G Berthelot, D Safran, P Even, H Kafe. Penetration of cefsulodin into bronchial secretions. Chemotherapy. 1984; 30(4):205-10. doi: 10.1159/000238269. [PMID: 6744972]
  • I Cabezudo, R L Thompson, R F Selden, S H Guenthner, R P Wenzel. Cefsulodin sodium therapy in cystic fibrosis patients. Antimicrobial agents and chemotherapy. 1984 Jan; 25(1):4-6. doi: 10.1128/aac.25.1.4. [PMID: 6422844]
  • C Penalba, P M Girard, A C Cremieux, C Michelet, A G Saimot, S Kernbaum. [Efficacy and reversible nephrotoxicity of cefsulodin during treatment of septicemia from Pseudomonas aeruginosa infection of a pacemaker]. Annales de medecine interne. 1984; 135(7):519-22. doi: . [PMID: 6517423]
  • I M Ackers, C M Myers, J L Blumer. Determination of cefsulodin in biological fluids by high-pressure liquid chromatography. Therapeutic drug monitoring. 1984; 6(1):91-5. doi: 10.1097/00007691-198403000-00015. [PMID: 6710560]
  • K Yamamura, M Nakao, J Yamada, T Yotsuyanagi. Simultaneous determinations of cefsulodin and cefotiam in serum and bone marrow blood by high-performance liquid chromatography. Journal of pharmaceutical sciences. 1983 Aug; 72(8):958-60. doi: 10.1002/jps.2600720833. [PMID: 6312012]
  • M Baumgärtner. [Cefoperazone, cefsulodin and ceftazidime--3 cephalosporins active against Pseudomonas in comparison with their monobactam analogs]. Zentralblatt fur Bakteriologie, Mikrobiologie und Hygiene. 1. Abt. Originale A, Medizinische Mikrobiologie, Infektionskrankheiten und Parasitologie = International journal of microbiology and hygiene. A, Medical microbiology, infectious.... 1983 Apr; 254(2):253-60. doi: . [PMID: 6326420]
  • G R Matzke, W F Keane. Cefsulodin pharmacokinetics in patients with various degrees of renal function. Antimicrobial agents and chemotherapy. 1983 Mar; 23(3):369-73. doi: 10.1128/aac.23.3.369. [PMID: 6847169]
  • A Arvidsson, G Alván, B Strandvik. Difference in renal handling of cefsulodin between patients with cystic fibrosis and normal subjects. Acta paediatrica Scandinavica. 1983 Mar; 72(2):293-4. doi: 10.1111/j.1651-2227.1983.tb09715.x. [PMID: 6837304]
  • A Momose, A Kasahara, T Fugono, E Mizuta. [The studies on distributions of cefsulodin and cefotiam to human aqueous humor and cornea]. The Japanese journal of antibiotics. 1982 Dec; 35(12):2879-93. doi: . [PMID: 6304364]
  • M Minamitani, K Hachimori, M Suzuki. [Clinical studies of cefsulodin in the pediatric field]. The Japanese journal of antibiotics. 1982 Nov; 35(11):2676-82. doi: . [PMID: 7169666]
  • T Nishimura, T Takashima, K Hiromatsu, K Tabuki. [Experimental and clinical evaluation of cefsulodin in the pediatric field]. The Japanese journal of antibiotics. 1982 Nov; 35(11):2699-707. doi: . [PMID: 6820395]
  • H Meguro, S Ozawa, Y Koike, M Hiraiwa, G Hashimoto, S Hashira, R Fujii, A Takahashi. [Clinical evaluation of cefsulodin in Pseudomonas infections in children]. The Japanese journal of antibiotics. 1982 Nov; 35(11):2639-51. doi: . [PMID: 7169664]
  • H Akita, S Iwata, Y Iwasaki, T Kanemitsu, H Hattori, K Jozaki, M Hotta, N Yamashita, S Nanri, K Sunagawa, T Iwata, M Osano, Y Ichihashi. [The experimental and clinical studies on cefsulodin in the pediatric field]. The Japanese journal of antibiotics. 1982 Nov; 35(11):2652-6. doi: . [PMID: 7169665]
  • T Tokiwa, K Miyoshi, T Takahashi, F Uda. [Subacute (5 weeks) subcutaneous toxicity study of cefsulodin using 3-week-old juvenile beagle dogs]. The Japanese journal of antibiotics. 1982 Nov; 35(11):1620-8. doi: NULL. [PMID: 7169660]
  • S Nakazawa, H Sato, K Niino, Y Hirama, A Narita, S Nakazawa, H Chikaoka, K Tazoe. [Evaluation of cefsulodin in the field of pediatrics]. The Japanese journal of antibiotics. 1982 Nov; 35(11):2633-8. doi: . [PMID: 7169663]
  • G R Granneman, L T Sennello. Precise high-performance liquid chromatographic procedure for the determination of cefsulodin, a new antipseudomonal cephalosporin antibiotic, in plasma. Journal of pharmaceutical sciences. 1982 Oct; 71(10):1112-5. doi: 10.1002/jps.2600711008. [PMID: 7143207]
  • T P Gibson, G R Granneman, J E Kallal, L T Sennello. Cefsulodin kinetics in renal impairment. Clinical pharmacology and therapeutics. 1982 May; 31(5):602-8. doi: 10.1038/clpt.1982.84. [PMID: 7075110]
  • J B Lecaillon, M C Rouan, C Souppart, N Febvre, F Juge. Determination of cefsulodin, cefotiam, cephalexin, cefotaxime, desacetyl-cefotaxime, cefuroxime and cefroxadin in plasma and urine by high-performance liquid chromatography. Journal of chromatography. 1982 Mar; 228(?):257-67. doi: 10.1016/s0378-4347(00)80438-7. [PMID: 6281285]
  • K Itakura, M Mitani, I Aoki, Y Usui. High performance liquid chromatographic assay of cefsulodin, cefotiam and cefmenoxime in serum and urine. Chemical & pharmaceutical bulletin. 1982 Feb; 30(2):622-7. doi: 10.1248/cpb.30.622. [PMID: 6284390]
  • G R Granneman, L T Sennello, R C Sonders, B Wynne, E W Thomas. Cefsulodin kinetics in healthy subjects after intramuscular and intravenous injection. Clinical pharmacology and therapeutics. 1982 Jan; 31(1):95-103. doi: 10.1038/clpt.1982.15. [PMID: 7053312]
  • P Federspil, W Schätzle, E Tiesler. Cefsulodin pharmacokinetics and otitis media. Archives of oto-rhino-laryngology. 1982; 236(2):123-30. doi: 10.1007/bf00454031. [PMID: 7150078]
  • N E Møller, C Koch, S Vesterhauge, K Jensen. Treatment of pulmonary Pseudomonas aeruginosa infection in cystic fibrosis with cefsulodin. Scandinavian journal of infectious diseases. 1982; 14(3):207-11. doi: 10.3109/inf.1982.14.issue-3.09. [PMID: 6815787]
  • U Mester, C Krasemann, H Werner. Cefsulodin concentrations in rabbit eyes after intravenous and subconjunctival administration. Ophthalmic research. 1982; 14(2):129-34. doi: 10.1159/000265184. [PMID: 7088497]
  • I Yamazaki, Y Shirakawa, T Fugono. Comparison of the renal excretory mechanisms of cefmenoxime and other cephalosporins: effect of para-aminohippurate on renal clearance and intrarenal distribution of cephalosporins in rabbits. The Journal of antibiotics. 1981 Nov; 34(11):1476-85. doi: 10.7164/antibiotics.34.1476. [PMID: 6274834]
  • P Veyssier, E Dusehu. [Cefsulodine concentrations in cerebral ventricles during parenteral treatment of ventriculitis due to Pseudomonas aeruginosa (author's transl)]. La Nouvelle presse medicale. 1981 Oct; 10(35):2881-2. doi: . [PMID: 7290939]
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  • Z Landau, H Halkin, E Rubinstein. Interstitial fluid concentrations of cefsulodin, azlocillin and carbenicillin. Scandinavian journal of infectious diseases. 1981; 13(3):227-32. doi: 10.3109/inf.1981.13.issue-3.11. [PMID: 7313576]
  • G Burmann, G Mertens, E Schulz, K Sack. [Nephrotoxicity of cefsulodin: experimental studies in animals (author's transl)]. Infection. 1981; 9(5):233-8. doi: 10.1007/bf01640722. [PMID: 6795129]
  • F D Daschner, B Metz, G Spillner, W Buzello, V Schlosser. Concentrations of cefamandole and cefsulodin in serum, heart valves, subcutaneous tissue, and muscle of patients undergoing open-heart surgery. The Journal of infectious diseases. 1980 Aug; 142(2):290. doi: 10.1093/infdis/142.2.290. [PMID: 7410901]
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