Atropine sulfate monohydrate (BioDeep_00000858908)
代谢物信息卡片
Atropine sulfate monohydrate
化学式: C34H50N2O11S (694.313515)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CN1C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3.CN1C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3.O.OS(=O)(=O)O
InChI: 1-5(2,3)4
描述信息
C78272 - Agent Affecting Nervous System > C66880 - Anticholinergic Agent > C29704 - Antimuscarinic Agent
同义名列表
1 个代谢物同义名
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Riccardo Lorrai, Dario Cavaterra, Sara Giammaria, Diego Sbardella, Grazia Raffaella Tundo, Alessandra Boccaccini. Eye Diseases: When the Solution Comes from Plant Alkaloids.
Planta medica.
2024 May; 90(6):426-439. doi:
10.1055/a-2283-2350. [PMID: 38452806] - F Rafique, M N Mushtaq, H Ahmed, W Younis. Evaluation and estimation of diuretic activity of the linalyl acetate in the rats.
Brazilian journal of biology = Revista brasleira de biologia.
2024; 83(?):e277354. doi:
10.1590/1519-6984.277354. [PMID: 38452187] - Xiehe Kong, Guang Yang, Zhi Chen, Rong Han, Yue Zhao, Li Zeng, Xiaocong Guo, Zheng Shi, Dan Zhang, Yanting Yang, Jie Liu, Xingtao Zhou, Xiaopeng Ma. Addition of Auricular Acupoint Stimulation to 0.01\% Atropine for Myopia: 12-Month Results from a Randomized Trial.
Journal of integrative and complementary medicine.
2023 Sep; 29(9):574-583. doi:
10.1089/jicm.2022.0769. [PMID: 36971804] - Jun-Yuan Guo, Bin-Bin Han, Nai-Guang Jia. Atropine combined with dopamine in a patient with sinus bradycardia scheduled for laparoscopic surgery.
Asian journal of surgery.
2023 Aug; ?(?):. doi:
10.1016/j.asjsur.2023.08.012. [PMID: 37597976] - Zahra Tardast, Alireza Iranbakhsh, Mostafa Ebadi, Zahra Oraghi Ardebili. Carboxylic acid-functionalized multiwalled carbon nanotubes (COOH-MWCNTs) improved production of atropine in callus of Datura inoxia by influencing metabolism, gene regulation, and DNA cytosine methylation; an in vitro biological assessment.
Plant physiology and biochemistry : PPB.
2023 Aug; 202(?):107975. doi:
10.1016/j.plaphy.2023.107975. [PMID: 37634333] - Shaida Mahmoudi, Mohamad Javad Chaichi, Mojtaba Shamsipur, Ome Leila Nazari, Abdolrauf SamadiMaybodi. Fe3 O4 and bimetal-organic framework Zn/Mg composites peroxides- like catalyze luminol chemiluminescence for specific measurement of atropine in Datura plant.
Luminescence : the journal of biological and chemical luminescence.
2023 Jul; ?(?):. doi:
10.1002/bio.4557. [PMID: 37455562] - Shaida Mahmoudi, Mohamad Javad Chaichi, Mojtaba Shamsipur, Ome Leila Nazari, Abdol Rauf Samadi Mayodi. Determination of Atropine by HPLC in Plant of Datura by Liquid-Liquid Extraction and Magnet Solid-Phase Extraction.
Journal of chromatographic science.
2023 Jun; ?(?):. doi:
10.1093/chromsci/bmad041. [PMID: 37316168] - Ana Rita Soares Mateus, Carmen Crisafulli, Matilde Vilhena, Sílvia Cruz Barros, Angelina Pena, Ana Sanches Silva. The Bright and Dark Sides of Herbal Infusions: Assessment of Antioxidant Capacity and Determination of Tropane Alkaloids.
Toxins.
2023 03; 15(4):. doi:
10.3390/toxins15040245. [PMID: 37104183] - Monique de Nijs, Colin Crews, Folke Dorgelo, Susan MacDonald, Patrick P J Mulder. Emerging Issues on Tropane Alkaloid Contamination of Food in Europe.
Toxins.
2023 Jan; 15(2):. doi:
10.3390/toxins15020098. [PMID: 36828413] - Zengying Wang, Pengfei Wang, Bohua Jiang, Yifei Meng, Sufang Qie, Zhipeng Yan. The efficacy and safety of 0.01\% atropine alone or combined with orthokeratology for children with myopia: A meta-analysis.
PloS one.
2023; 18(7):e0282286. doi:
10.1371/journal.pone.0282286. [PMID: 37494360] - Farheen Tariq, Rabia Mobeen, Xinhai Wang, Xiao Lin, Qingdong Bao, Jinhui Liu, Hua Gao. Advances in myopia prevention strategies for school-aged children: a comprehensive review.
Frontiers in public health.
2023; 11(?):1226438. doi:
10.3389/fpubh.2023.1226438. [PMID: 37655278] - Lorena González-Gómez, Sonia Morante-Zarcero, Jorge A M Pereira, José S Câmara, Isabel Sierra. Improved Analytical Approach for Determination of Tropane Alkaloids in Leafy Vegetables Based on µ-QuEChERS Combined with HPLC-MS/MS.
Toxins.
2022 Sep; 14(10):. doi:
10.3390/toxins14100650. [PMID: 36287919] - Emad A Ahmed, Mayyadah A Alkuwayti, Hairul-Islam M Ibrahim. Atropine Is a Suppressor of Epithelial-Mesenchymal Transition (EMT) That Reduces Stemness in Drug-Resistant Breast Cancer Cells.
International journal of molecular sciences.
2022 Aug; 23(17):. doi:
10.3390/ijms23179849. [PMID: 36077256] - Ewelina Kowalczyk, Krzysztof Kwiatek. Scopolamine and atropine in feeds - determination with liquid chromatography mass spectrometry.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment.
2022 May; 39(5):977-989. doi:
10.1080/19440049.2022.2037724. [PMID: 35302907] - Ashok Kumar Pannu, Sahil Garg, Ashish Bhalla, Deba Prasad Dhibar, Navneet Sharma. Lipid emulsion for the treatment of acute organophosphate poisoning: an Open-Label randomized trial.
Clinical toxicology (Philadelphia, Pa.).
2022 May; 60(5):602-608. doi:
10.1080/15563650.2021.2013496. [PMID: 34928182] - Marquis Von Angelo Syquio G Joson, Fides Roxanne M Castor, Charmaine Victoria Micu-Oblefias. Role of intravenous lipid emulsion therapy and packed red blood cell transfusion as adjuvant treatment in the management of a child with severe organophosphate poisoning (chlorpyrifos).
BMJ case reports.
2022 Apr; 15(4):. doi:
10.1136/bcr-2021-246381. [PMID: 35396244] - Nikhitha Lakshmi, Ameer Basha Shaik, Pragya Paramita Pal, Sajeli Begum Ahil, Ramya Vittal, Saida Naik, Uma Devi Gali, Vidya Sagar Bokka. Piperine, Reserpine and β-Sitosterol Attenuate Stem Rot (Sclerotium rolfsii Sacc.) of Groundnut by Inducing the Secretion of defense Enzymes and Phenolic Acids.
Chemistry & biodiversity.
2022 Apr; 19(4):e202100880. doi:
10.1002/cbdv.202100880. [PMID: 35182415] - Sabrina Schmoll, Katrin Romanek, Gabriel Zorn, Hans Eiglmeier, Florian Eyer. Anticholinergic syndrome after atropine overdose in a supposedly homeopathic solution: a case report.
Clinical toxicology (Philadelphia, Pa.).
2022 Feb; 60(2):252-254. doi:
10.1080/15563650.2021.1918704. [PMID: 33988064] - Samah M El Sohafy, Eman Shawky, Shaimaa M Sallam. Effect of ontogeny on the content of the hallucinogenic alkaloids atropine and scopolamine in the different organs of some Solanaceae plants.
Natural product research.
2021 Dec; 35(24):5894-5898. doi:
10.1080/14786419.2020.1800698. [PMID: 32748646] - Małgorzata Gołąb, Martyna Przybyłowska, Petr Kubáň, Petra Itterheimová, Michał Woźniakiewicz. Development of CE-C4D Method for Determination Tropane Alkaloids.
Molecules (Basel, Switzerland).
2021 Sep; 26(19):. doi:
10.3390/molecules26195749. [PMID: 34641293] - Q Chen, Z Jiang, J Zhang, L Cao, Z Chen. Arecoline hydrobromide enhances jejunum smooth muscle contractility via voltage-dependent potassium channels in W/Wv mice.
Physiological research.
2021 07; 70(3):437-446. doi:
10.33549/physiolres.934557. [PMID: 33982580] - Sakib Aman, Shrebash Paul, Fazle Rabbi Chowdhury. Management of Organophosphorus Poisoning: Standard Treatment and Beyond.
Critical care clinics.
2021 Jul; 37(3):673-686. doi:
10.1016/j.ccc.2021.03.011. [PMID: 34053713] - Mariana Koetz, Luiz C Klein-Junior, Marí C Santos, Thamires A da Silva, Natally S B Toson, Amélia T Henriques. An ultrasound assisted extraction-solid-phase extraction-ultra-performance liquid chromatography combined strategy for atropine determination in Atropa belladonna leaves.
Biomedical chromatography : BMC.
2021 May; 35(5):e5053. doi:
10.1002/bmc.5053. [PMID: 33314218] - Bandar Ali Alyami, Suneela Akhtar, - Alamgeer, Taseer Ahmad, Ali Omar Alqarni, Yahya Saeed Alqahtani, Mater Hussen Mahnashi, Sumera Qasim, Hafiz Muhammad Irfan, Muhammad Akram, Humayun Riaz, Rukhsana Anwar. Evaluation of phytochemical, anti-oxidant and cardiac depressant effect of Rumex dentatus by using Langendorff's isolated heart apparatus.
Pakistan journal of pharmaceutical sciences.
2021 Mar; 34(2(Supplementary)):671-677. doi:
". [PMID: 34275801] - Lingjiang Zeng, Qiaozhuo Zhang, Chunxue Jiang, Yueyue Zheng, Youwei Zuo, Jianbo Qin, Zhihua Liao, Hongping Deng. Development of Atropa belladonna L. Plants with High-Yield Hyoscyamine and without Its Derivatives Using the CRISPR/Cas9 System.
International journal of molecular sciences.
2021 Feb; 22(4):. doi:
10.3390/ijms22041731. [PMID: 33572199] - Oluwaseyi K Wakeel, Abraham I Abe, Oluropo B Awosan, Mokaila K Olapade, Temitope J Olatoyan-Layonu, Olugbenga A Olowe, Oluwaseyi A Adeyeba. Anti-Nociceptive and Anti-Inflammatory Effects of Stem Bark Extract of Ficus Capensis Thunb (Moraceae) by Bioactivity Fractionation.
Anti-inflammatory & anti-allergy agents in medicinal chemistry.
2021; 20(2):206-218. doi:
10.2174/1871523019666200825194616. [PMID: 32842947] - Suzhen Wang, Jie Wang, Ningli Wang. Combined Orthokeratology with Atropine for Children with Myopia: A Meta-Analysis.
Ophthalmic research.
2021; 64(5):723-731. doi:
10.1159/000510779. [PMID: 32781450] - S U Xu, Jinhai Zhai, K E Xu, Xingguo Zuo, Chenghua Wu, Tao Lin, L I Zeng. M1 macrophages-derived exosomes miR-34c-5p regulates interstitial cells of Cajal through targeting SCF.
Journal of biosciences.
2021; 46(?):. doi:
. [PMID: 34544909] - Ingo Hartter, Daniela Remane, Christian Rabe, Dirk K Wissenbach, Frank T Peters, Florian Eyer. Surviving chlormequat poisoning - pharmacokinetics and the role of atropine.
Clinical toxicology (Philadelphia, Pa.).
2021 01; 59(1):74-76. doi:
10.1080/15563650.2020.1758326. [PMID: 32336166] - Joe-Anthony Rotella, Shaun L Greene, Zeff Koutsogiannis, Andis Graudins, Yit Hung Leang, Kelvin Kuan, Helen Baxter, Elyssia Bourke, Anselm Wong. Treatment for beta-blocker poisoning: a systematic review.
Clinical toxicology (Philadelphia, Pa.).
2020 10; 58(10):943-983. doi:
10.1080/15563650.2020.1752918. [PMID: 32310006] - Hira Asif, - Alamgeer, Muhammad Ishfaq Ahmad, Nasser Hadal Alotaibi, Khalid Saad Alharbi, Syed Nasir Abbas Bukhari, Hammad Saleem, Marcello Locatelli. Phytochemical analysis and reappraisal of diuretic activity of Delphinium brunonianum Royle and its mode of action in experimental rats.
Pakistan journal of pharmaceutical sciences.
2020 Jul; 33(4(Supplementary)):1833-1838. doi:
NULL. [PMID: 33612467] - A B Olorukooba, S Odoma. Elucidation of the possible mechanism of analgesic action of methanol stem bark extract of Uapaca togoensis pax in mice.
Journal of ethnopharmacology.
2019 Dec; 245(?):112156. doi:
10.1016/j.jep.2019.112156. [PMID: 31415847] - Tycho J Olgers, Jan C Ter Maaten, Daan J Touw. Remember Atropine for 'Killer B's'.
The Journal of emergency medicine.
2019 11; 57(5):731. doi:
10.1016/j.jemermed.2018.09.061. [PMID: 31761009] - Jawad Zaheer, Qazi Najam-Us-Saqib, Asif Mehmmod Hashmi, Muhammad Mukhtiar, Sadia Zafar, Muhammad Riaz, Ghulam Rasool, Muhammad Akram, Syed Muhammad-Ali Shah, Saher Rahat, Faid Said Khan. Ex-vivo abortifacient activity of Androsace foliosa n-hexane leaves extract on isolated rabbit uterus.
Pakistan journal of pharmaceutical sciences.
2019 Sep; 32(5(Supplementary)):2333-2339. doi:
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Journal of plant research.
2019 Jul; 132(4):473-480. doi:
10.1007/s10265-019-01111-z. [PMID: 31020486] - Kilambi Pundarikakshudu, Anil Kumar Sharma, Chaitanya J Bhatt, Niranjan S Kanaki. Development and Validation of a High-Performance Thin-Layer Chromatographic (HPTLC) Method for Simultaneous Quantification of Reserpine, Atropine, and Piperine in Sarpagandha Ghanvati, a Classical Ayurvedic Preparation.
Journal of AOAC International.
2019 Jul; 102(4):1021-1026. doi:
10.5740/jaoacint.18-0382. [PMID: 30558695] - Szymon Chowański, Joanna Pacholska-Bogalska, Grzegorz Rosiński. Cholinergic Agonists and Antagonists Have an Effect on the Metabolism of the Beetle Tenebrio Molitor.
Molecules (Basel, Switzerland).
2018 Dec; 24(1):. doi:
10.3390/molecules24010017. [PMID: 30577556] - Yunfei Ma, Lianfang Du, Fan Li, Zhengqiu Zhu. Use of atropine in four-dimensional hysterosalpingo-contrast sonography: Does it suppress pain during infertility examination?.
Clinical and experimental pharmacology & physiology.
2018 12; 45(12):1334-1340. doi:
10.1111/1440-1681.12919. [PMID: 29381225] - Harald John, Michael Rychlik, Horst Thiermann, Christian Schmidt. Simultaneous quantification of atropine and scopolamine in infusions of herbal tea and Solanaceae plant material by matrix-assisted laser desorption/ionization time-of-flight (tandem) mass spectrometry.
Rapid communications in mass spectrometry : RCM.
2018 Nov; 32(22):1911-1921. doi:
10.1002/rcm.8264. [PMID: 30117208] - Luísa Nathália Bolda Mariano, Thaise Boeing, Rita de Cássia Melo Vilhena de Andrade Fonseca da Silva, Valdir Cechinel-Filho, Rivaldo Niero, Luisa Mota da Silva, Priscila de Souza, Sérgio Faloni de Andrade. Preclinical evaluation of the diuretic and saluretic effects of (-)-epicatechin and the result of its combination with standard diuretics.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2018 Nov; 107(?):520-525. doi:
10.1016/j.biopha.2018.08.045. [PMID: 30114635] - Wataru Suto, Yusuke Ando, Takahiro Hirabayashi, Fumiko Takenoya, Seiji Shioda, Junzo Kamei, Hiroyasu Sakai, Yoshihiko Chiba. Prostaglandin D₂ Induces Ca2+ Sensitization of Contraction without Affecting Cytosolic Ca2+ Level in Bronchial Smooth Muscle.
International journal of molecular sciences.
2018 Oct; 19(10):. doi:
10.3390/ijms19103036. [PMID: 30301147] - Jesús Marín-Sáez, Roberto Romero-González, Antonia Garrido Frenich, Francisco Javier Egea-González. Screening of drugs and homeopathic products from Atropa belladonna seed extracts: Tropane alkaloids determination and untargeted analysis.
Drug testing and analysis.
2018 Oct; 10(10):1579-1589. doi:
10.1002/dta.2416. [PMID: 29808589] - Ritesh G Menezes, Muhammad Shariq Usman, Syed Ather Hussain, Mohammed Madadin, Tariq Jamal Siddiqi, Huda Fatima, Pradhum Ram, Syed Bilal Pasha, S Senthilkumaran, Tooba Qadir Fatima, Sushil Allen Luis. Cerbera odollam toxicity: A review.
Journal of forensic and legal medicine.
2018 Aug; 58(?):113-116. doi:
10.1016/j.jflm.2018.05.007. [PMID: 29778924] - Gunnar F Kwakye, Jennifer Jiménez, Jessica A Jiménez, Michael Aschner. Atropa belladonna neurotoxicity: Implications to neurological disorders.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2018 Jun; 116(Pt B):346-353. doi:
10.1016/j.fct.2018.04.022. [PMID: 29653183] - Elena S Catap, Markyn Jared L Kho, Maria Rexie R Jimenez. In vivo nonspecific immunomodulatory and antispasmodic effects of common purslane (Portulaca oleracea Linn.) leaf extracts in ICR mice.
Journal of ethnopharmacology.
2018 Apr; 215(?):191-198. doi:
10.1016/j.jep.2018.01.009. [PMID: 29325915] - Eeva J Vainio, Jaana Jurvansuu, Rafiqul Hyder, Muhammad Kashif, Tuula Piri, Tero Tuomivirta, Anna Poimala, Ping Xu, Salla Mäkelä, Dina Nitisa, Jarkko Hantula. Heterobasidion Partitivirus 13 Mediates Severe Growth Debilitation and Major Alterations in the Gene Expression of a Fungal Forest Pathogen.
Journal of virology.
2018 03; 92(5):. doi:
10.1128/jvi.01744-17. [PMID: 29237832] - Maria G Zizzo, Monica Frinchi, Domenico Nuzzo, Hyder A Jinnah, Giuseppa Mudò, Daniele F Condorelli, Francesco Caciagli, Renata Ciccarelli, Patrizia Di Iorio, Flavia Mulè, Natale Belluardo, Rosa Serio. Altered gastrointestinal motility in an animal model of Lesch-Nyhan disease.
Autonomic neuroscience : basic & clinical.
2018 03; 210(?):55-64. doi:
10.1016/j.autneu.2017.12.007. [PMID: 29305058] - Ashton D Lesiak, Kristen L Fowble, Rabi A Musah. A Rapid, High-Throughput Validated Method for the Quantification of Atropine in Datura stramonium Seeds Using Direct Analysis in Real Time-High Resolution Mass Spectrometry (DART-HRMS).
Methods in molecular biology (Clifton, N.J.).
2018; 1810(?):207-215. doi:
10.1007/978-1-4939-8579-1_18. [PMID: 29974430] - Songyan Wang, Lauren Z Oestricker, Michael J Wallendorf, Karin Sterl, Judit Dunai, C Rachel Kilpatrick, Bruce W Patterson, Dominic N Reeds, Burton M Wice. Cholinergic signaling mediates the effects of xenin-25 on secretion of pancreatic polypeptide but not insulin or glucagon in humans with impaired glucose tolerance.
PloS one.
2018; 13(2):e0192441. doi:
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International journal of molecular sciences.
2017 Dec; 19(1):. doi:
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The Journal of pharmacy and pharmacology.
2017 Nov; 69(11):1615-1624. doi:
10.1111/jphp.12785. [PMID: 28744880] - Priscila de Souza, Thaise Boeing, Lincon Bordignon Somensi, Camile Cecconi Cechinel-Zanchett, Jairo Kenupp Bastos, Marcel Petreanu, Rivaldo Niero, Valdir Cechinel-Filho, Luisa Mota da Silva, Sérgio Faloni de Andrade. Diuretic effect of extracts, fractions and two compounds 2α,3β,19α-trihydroxy-urs-12-en-28-oic acid and 5-hydroxy-3,6,7,8,4'-pentamethoxyflavone from Rubus rosaefolius Sm. (Rosaceae) leaves in rats.
Naunyn-Schmiedeberg's archives of pharmacology.
2017 Apr; 390(4):351-360. doi:
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Analytical chemistry.
2017 03; 89(6):3421-3429. doi:
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Urology.
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Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2017 Feb; 1043(?):202-208. doi:
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Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan.
2017; 58(2):86-95. doi:
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Journal of clinical apheresis.
2016 Oct; 31(5):467-9. doi:
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Journal of ethnopharmacology.
2016 Aug; 189(?):14-21. doi:
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Journal of basic and clinical physiology and pharmacology.
2016 Jun; 27(4):363-70. doi:
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British journal of clinical pharmacology.
2016 Mar; 81(3):462-70. doi:
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Acupuncture in medicine : journal of the British Medical Acupuncture Society.
2016 Feb; 34(1):33-9. doi:
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Experimental parasitology.
2015 Dec; 159(?):136-42. doi:
10.1016/j.exppara.2015.09.012. [PMID: 26429130] - Andrew Chadwick, Abigail Ash, James Day, Mark Borthwick. Accidental overdose in the deep shade of night: a warning on the assumed safety of 'natural substances'.
BMJ case reports.
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