fenproporex (BioDeep_00000858699)

   

Volatile Flavor Compounds


代谢物信息卡片


fenproporex

化学式: C12H16N2 (188.13134159999998)
中文名称: 芬普雷司
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(CC1=CC=CC=C1)NCCC#N
InChI: InChI=1S/C12H16N2/c1-11(14-9-5-8-13)10-12-6-3-2-4-7-12/h2-4,6-7,11,14H,5,9-10H2,1H3

描述信息

C78272 - Agent Affecting Nervous System > C29728 - Anorexiant

同义名列表

3 个代谢物同义名

fenproporex; Fenproporex; Fenproporex



数据库引用编号

7 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Lara M Gomes, Milena Carvalho-Silva, Letícia J Teixeira, Joyce Rebelo, Isabella T Mota, Rafaela Bilesimo, Monique Michels, Camila O Arent, Edemilson Mariot, Felipe Dal-Pizzol, Giselli Scaini, João Quevedo, Emilio L Streck. Omega-3 fatty acids and mood stabilizers alter behavioral and oxidative stress parameters in animals subjected to fenproporex administration. Metabolic brain disease. 2017 04; 32(2):519-528. doi: 10.1007/s11011-016-9942-7. [PMID: 27987060]
  • Kristiane de Cássia Mariotti, Roselena S Schuh, Priscila Ferranti, Rafael S Ortiz, Daniele Z Souza, Flavio Pechansky, Pedro E Froehlich, Renata P Limberger. Simultaneous analysis of amphetamine-type stimulants in plasma by solid-phase microextraction and gas chromatography-mass spectrometry. Journal of analytical toxicology. 2014 Sep; 38(7):432-7. doi: 10.1093/jat/bku063. [PMID: 25038769]
  • Camila S Model, Lara M Gomes, Giselli Scaini, Gabriela K Ferreira, Cinara L Gonçalves, Gislaine T Rezin, Amanda V Steckert, Samira S Valvassori, Roger B Varela, João Quevedo, Emilio L Streck. Omega-3 fatty acids alter behavioral and oxidative stress parameters in animals subjected to fenproporex administration. Metabolic brain disease. 2014 Mar; 29(1):185-92. doi: 10.1007/s11011-013-9473-4. [PMID: 24385143]
  • Eloisa Comiran, Daniele Zago Souza, Paula Otero Boehl, Kristiane de Cássia Mariotti, Flavio Pechansky, Paulina do Carmo Arruda Vieira Duarte, Raquel Brandini De Boni, Pedro Eduardo Fröehlich, Renata Pereira Limberger. Fenproporex and amphetamine pharmacokinetics in oral fluid after controlled oral administration of fenproporex. Therapeutic drug monitoring. 2012 Oct; 34(5):545-53. doi: 10.1097/ftd.0b013e318263c6c5. [PMID: 22846898]
  • L M De Carvalho, P A Cohen, C V Silva, A P L Moreira, T M Falcão, T R Dal Molin, G Zemolin, M Martini. A new approach to determining pharmacologic adulteration of herbal weight loss products. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment. 2012; 29(11):1661-7. doi: 10.1080/19440049.2012.706834. [PMID: 22849359]
  • Pieter A Cohen. Imported fenproporex-based diet pills from Brazil: a report of two cases. Journal of general internal medicine. 2009 Mar; 24(3):430-3. doi: 10.1007/s11606-008-0878-4. [PMID: 19096898]
  • Thomas Kraemer, Thomas Pflugmann, Michael Bossmann, Nicole M Kneller, Frank T Peters, Liane D Paul, Dietmar Springer, Roland F Staack, Hans H Maurer. Fenproporex N-dealkylation to amphetamine--enantioselective in vitro studies in human liver microsomes as well as enantioselective in vivo studies in Wistar and Dark Agouti rats. Biochemical pharmacology. 2004 Sep; 68(5):947-57. doi: 10.1016/j.bcp.2004.05.009. [PMID: 15294457]
  • Adriane Maria Rodrigues, Rosana Bento Radominski, Henrique de Lacerda Suplicy, Sergio Monteiro De Almeida, Patricia Artigas Niclewicz, Cesar Luiz Boguszewski. The cerebrospinal fluid/serum leptin ratio during pharmacological therapy for obesity. The Journal of clinical endocrinology and metabolism. 2002 Apr; 87(4):1621-6. doi: 10.1210/jcem.87.4.8420. [PMID: 11932292]
  • R R Bell, S B Crookham, W A Dunn, K M Grates, T M Reiber. A contemporaneous finding of fenproporex in a polydrug suicide. Journal of analytical toxicology. 2001 Oct; 25(7):652-6. doi: 10.1093/jat/25.7.652. [PMID: 11599619]
  • T Kraemer, G A Theis, A A Weber, H H Maurer. Studies on the metabolism and toxicological detection of the amphetamine-like anorectic fenproporex in human urine by gas chromatography-mass spectrometry and fluorescence polarization immunoassay. Journal of chromatography. B, Biomedical sciences and applications. 2000 Jan; 738(1):107-18. doi: 10.1016/s0378-4347(99)00497-1. [PMID: 10778932]
  • J T Cody, S Valtier, S Stillman. Amphetamine and fenproporex levels following multidose administration of fenproporex. Journal of analytical toxicology. 1999 May; 23(3):187-94. doi: 10.1093/jat/23.3.187. [PMID: 10369328]
  • J T Cody, S Valtier. Detection of amphetamine following administration of fenproporex. Journal of analytical toxicology. 1996 Oct; 20(6):425-31. doi: 10.1093/jat/20.6.425. [PMID: 8889679]
  • R de la Torre, R Badia, G Gonzàlez, M García, M J Pretel, M Farré, J Segura. Cross-reactivity of stimulants found in sports drug testing by two fluorescence polarization immunoassays. Journal of analytical toxicology. 1996 May; 20(3):165-70. doi: 10.1093/jat/20.3.165. [PMID: 8735197]
  • A C Lopes, L Longhi, L Kulay, E Knobel, V L Delascio Lopes, D R Sustovich. The effect of N-2-cyano-ethylamphetamine HCl on total lipids contents of heart (biochemical study) and aorta (histochemical study) of female pregnant rats. Rivista italiana di ginecologia. 1977 Sep; 58(5):409-13. doi: ". [PMID: 555040]
  • G Tognoni, P L Morselli, S Garattini. Amphetamine concentrations in rat brain and human urine after fenproporex administration. European journal of pharmacology. 1972 Oct; 20(1):125-6. doi: 10.1016/0014-2999(72)90227-0. [PMID: 4637940]