oxidopamine (BioDeep_00000858697)
Chemicals and Drugs
代谢物信息卡片
oxidopamine
化学式: C8H11NO3 (169.0738896)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=C(C(=CC(=C1O)O)O)CCN
InChI: InChI=1S/C8H11NO3/c9-2-1-5-3-7(11)8(12)4-6(5)10/h3-4,10-12H,1-2,9H2
描述信息
A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinsons disease).
D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents > D013565 - Sympatholytics
C78272 - Agent Affecting Nervous System > C66883 - Dopamine Antagonist
D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents
同义名列表
1 个代谢物同义名
数据库引用编号
7 个数据库交叉引用编号
- ChEBI: CHEBI:78741
- KEGGdrug: D05294
- PubChem: 4624
- ChEMBL: CHEMBL337702
- MeSH: Oxidopamine
- CAS: 1199-18-4
- MetaboLights: MTBLC78741
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Luqi Kong, Yilan Wang, Zhou Tong, Rongrong Dai, Abdulla Yusuf, Lifen Du, Bin Liu, Zhiyong Huang, Linzhen Hu. Granulathiazole A protects 6-OHDA-induced Parkinson's disease from ferroptosis via activating Nrf2/HO-1 pathway.
Bioorganic chemistry.
2024 Jun; 147(?):107399. doi:
10.1016/j.bioorg.2024.107399. [PMID: 38678778] - Yendubé T Kantati, Magloire K Kodjo, Benjamin Lefranc, Magali Basille-Dugay, Sébastien Hupin, Isabelle Schmitz, Jérôme Leprince, Messanvi Gbeassor, David Vaudry. Neuroprotective Effect of Sterculia setigera Leaves Hydroethanolic Extract.
Journal of molecular neuroscience : MN.
2024 Apr; 74(2):44. doi:
10.1007/s12031-024-02222-6. [PMID: 38630337] - Lan Yu, Xiaolu Hu, Rongrong Xu, Yimeng Zhao, Lijuan Xiong, Jiaxuan Ai, Xing Wang, Xiaoqing Chen, Yinying Ba, Zhikai Xing, Chongye Guo, Shuangli Mi, Xia Wu. Piperine promotes PI3K/AKT/mTOR-mediated gut-brain autophagy to degrade α-Synuclein in Parkinson's disease rats.
Journal of ethnopharmacology.
2024 Mar; 322(?):117628. doi:
10.1016/j.jep.2023.117628. [PMID: 38158101] - Wanran Huang, Yanni Wang, Wei Huang. Mangiferin alleviates 6-OHDA-induced Parkinson's disease by inhibiting AKR1C3 to activate Wnt signaling pathway.
Neuroscience letters.
2024 Jan; 821(?):137608. doi:
10.1016/j.neulet.2023.137608. [PMID: 38142926] - Renata Perlikowska, Joana Silva, Celso Alves, Patricia Susano, Małgorzata Zakłos-Szyda, Agnieszka Skibska, Anna Adamska-Bartłomiejczyk, Karol Wtorek, Jean-Claude do Rego, Jean-Luc do Rego, Alicja Kluczyk, Rui Pedrosa. Neuroprotective and Anti-inflammatory Effects of Rubiscolin-6 Analogs with Proline Surrogates in Position 2.
Neurochemical research.
2023 Dec; ?(?):. doi:
10.1007/s11064-023-04070-z. [PMID: 38117448] - Patricia Alejandra Brand-Rubalcava, Aldo Rafael Tejeda-Martínez, Orfil González-Reynoso, Angelica Yanet Nápoles-Medina, Verónica Chaparro-Huerta, Mario Eduardo Flores-Soto. β-Caryophyllene decreases neuroinflammation and exerts neuroprotection of dopaminergic neurons in a model of hemiparkinsonism through inhibition of the NLRP3 inflammasome.
Parkinsonism & related disorders.
2023 Dec; 117(?):105906. doi:
10.1016/j.parkreldis.2023.105906. [PMID: 37924806] - Katherine S Morton, Jessica H Hartman, Nathan Heffernan, Ian T Ryde, Isabel W Kenny-Ganzert, Lingfeng Meng, David R Sherwood, Joel N Meyer. Chronic high-sugar diet in adulthood protects Caenorhabditis elegans from 6-OHDA-induced dopaminergic neurodegeneration.
BMC biology.
2023 11; 21(1):252. doi:
10.1186/s12915-023-01733-9. [PMID: 37950228] - Albert Layo Costa de Assis, Patricia de Araújo Rodrigues, Selene Maia de Morais, Ana Livya Moreira Rodrigues, Jessica Maria Pessoa Gomes, Tyciane de Souza Nascimento, Alfaete Vieira Oliveira, Mayara Sandrielly Soares de Aguiar, Geanne Matos de Andrade. Byrsonima sericea Ethanol Extract Protected PC12 Cells from the Oxidative Stress and Apoptosis Induced by 6-Hydroxydopamine.
Neurochemical research.
2023 Sep; ?(?):. doi:
10.1007/s11064-023-04028-1. [PMID: 37725292] - Nina I Uspalenko, Alexei A Mosentsov, Natalia V Khmil, Lyubov L Pavlik, Natalia V Belosludtseva, Natalia V Khunderyakova, Maria I Shigaeva, Vasilisa P Medvedeva, Anton E Malkov, Valentina F Kitchigina, Galina D Mironova. Uridine as a Regulator of Functional and Ultrastructural Changes in the Brain of Rats in a Model of 6-OHDA-Induced Parkinson's Disease.
International journal of molecular sciences.
2023 Sep; 24(18):. doi:
10.3390/ijms241814304. [PMID: 37762607] - Elham Ramazani, Faeze Ebrahimpour, Seyed Ahmad Emami, Abolfazl Shakeri, Behjat Javadi, Amirhossein Sahebkar, Zahra Tayarani-Najaran. Neuroprotective effects of Sesamum indicum, sesamin and sesamolin against 6-OHDA-induced apoptosis in PC12 cells.
Recent advances in food, nutrition & agriculture.
2023 Aug; ?(?):. doi:
10.2174/2772574x14666230804151124. [PMID: 37539928] - Xiaolu Hu, Lan Yu, Yatong Li, Xiaoxi Li, Yimeng Zhao, Lijuan Xiong, Jiaxuan Ai, Qijun Chen, Xing Wang, Xiaoqing Chen, Yinying Ba, Yaonan Wang, Xia Wu. Piperine improves levodopa availability in the 6-OHDA-lesioned rat model of Parkinson's disease by suppressing gut bacterial tyrosine decarboxylase.
CNS neuroscience & therapeutics.
2023 Aug; ?(?):. doi:
10.1111/cns.14383. [PMID: 37528534] - Victor Silva da Fonsêca, Valeria de Cassia Goncalves, Mario Augusto Izidoro, Antônio-Carlos Guimarães de Almeida, Fernando Luiz Affonso Fonseca, Fulvio Alexandre Scorza, Josef Finsterer, Carla Alessandra Scorza. Parkinson's Disease and the Heart: Studying Cardiac Metabolism in the 6-Hydroxydopamine Model.
International journal of molecular sciences.
2023 Jul; 24(15):. doi:
10.3390/ijms241512202. [PMID: 37569578] - Tanatcha Sanguanphun, Sukrit Promtang, Nilubon Sornkaew, Nakorn Niamnont, Prasert Sobhon, Krai Meemon. Anti-Parkinson Effects of Holothuria leucospilota-Derived Palmitic Acid in Caenorhabditis elegans Model of Parkinson's Disease.
Marine drugs.
2023 Feb; 21(3):. doi:
10.3390/md21030141. [PMID: 36976190] - Fangru Wang, Ting Jin, Hongyuan Li, Houfang Long, Ying Liu, Sha Jin, Yuyuan Lu, Yinghua Peng, Cong Liu, Lihui Zhao, Xiaohui Wang. Cannabidivarin alleviates α-synuclein aggregation via DAF-16 in Caenorhabditis elegans.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
2023 02; 37(2):e22735. doi:
10.1096/fj.202200278rr. [PMID: 36583706] - Chenjing Ma, Ying Feng, Xian Li, Long Sun, Zhao He, Jin Gan, Minjie He, Xin Zhang, Xiaoming Chen. Potential Therapeutic Effects of Policosanol from Insect Wax on Caenorhabditis elegans Models of Parkinson's Disease.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology.
2023 Jan; ?(?):. doi:
10.1007/s11481-022-10057-4. [PMID: 36637699] - Ayşe Nur Demiryürek, Özge Göktürk, Ahmet Saracaloglu, Seniz Demiryürek, Abdullah Tuncay Demiryürek. Protective effects of verbenalin and (+)-eudesmin against 6-hydroxydopamine-induced oxidative/nitrosative stress in SH-SY5Y cells.
Molecular biology reports.
2023 Jan; 50(1):331-338. doi:
10.1007/s11033-022-08039-z. [PMID: 36331750] - Chang-Long He, Yong Tang, Jian-Ming Wu, Tao Long, Lu Yu, Jin-Feng Teng, Wen-Qiao Qiu, Rong Pan, Chong-Lin Yu, Da-Lian Qin, An-Guo Wu, Xiao-Gang Zhou. Chlorogenic acid delays the progression of Parkinson's disease via autophagy induction in Caenorhabditis elegans.
Nutritional neuroscience.
2023 Jan; 26(1):11-24. doi:
10.1080/1028415x.2021.2009993. [PMID: 34927571] - Sara Abidar, Lucian Hritcu, Mohamed Nhiri. The Natural Neuroprotective Compounds Used in the 6-Hydroxydopamine- Induced Parkinson's Disease in Zebrafish: The Current Applications and Perspectives.
CNS & neurological disorders drug targets.
2023; 22(10):1472-1483. doi:
10.2174/1871527322666221028152600. [PMID: 36306449] - Fahim Muhammad, Yan Liu, Ningbo Wang, Longhe Zhao, Yangtao Zhou, Hui Yang, Hongyu Li. Neuroprotective effects of cannabidiol on dopaminergic neurodegeneration and α-synuclein accumulation in C. elegans models of Parkinson's disease.
Neurotoxicology.
2022 12; 93(?):128-139. doi:
10.1016/j.neuro.2022.09.001. [PMID: 36108815] - Qili Lu, Noha A Gouda, Guofeng Quan, Hossam Nada, Ahmed Elkamhawy, Dongho Lee, Chang Hoon Lee, Jungsook Cho, Kyeong Lee. Novel cudraisoflavone J derivatives as potent neuroprotective agents for the treatment of Parkinson's disease via the activation of Nrf2/HO-1 signaling.
European journal of medicinal chemistry.
2022 Nov; 242(?):114692. doi:
10.1016/j.ejmech.2022.114692. [PMID: 36029560] - Zohre Sadeghian, Shahla Eyvari-Brooshghalan, Mohammadmahdi Sabahi, Nahal Nourouzi, Rasool Haddadi. Post treatment with Gastrodin suppresses oxidative stress and attenuates motor disorders following 6-OHDA induced Parkinson disease.
Neuroscience letters.
2022 11; 790(?):136884. doi:
10.1016/j.neulet.2022.136884. [PMID: 36162540] - Song-Yu Guo, Rong-Xiao Guan, Xiao-Dong Chi, Yue-Zhang, Ao-Ran Sui, Wei Zhao, Kundu Supratik, Jin-Yi Yang, Jie Zhao, Shao Li. Scorpion venom heat-resistant synthetic peptide protects dopamine neurons against 6-hydroxydopamine neurotoxicity in C. elegans.
Brain research bulletin.
2022 11; 190(?):195-203. doi:
10.1016/j.brainresbull.2022.09.022. [PMID: 36191729] - Rafael Carneiro Bastos, Carlos Franciney Moreira Vasconcelos, Marcela Bezerra Paiva, Thomas Dominik de Sousa Dos Reis, Ricardo Basto Souza, Hélcio Silva Dos Santos, Paulo Nogueira Bandeira, Lissiana Magna Vasconcelos Aguiar, Rodrigo Maranguape Silva da Cunha. Assessment of antioxidant and antiparkinsonian potential of a new diterpene isolated from Croton argyrophylloides.
Free radical research.
2022 Nov; 56(11-12):760-770. doi:
10.1080/10715762.2023.2176763. [PMID: 36814389] - Yu-Jie Li, Juan Li, Lan Xie, Jun-Yu Zhou, Qiu-Xuan Li, Rui-Yuan Yang, Yan-Ping Liu, Yan-Hui Fu. Monoterpenoid indole alkaloids with potential neuroprotective activities from the stems and leaves of Melodinus cochinchinensis.
Natural product research.
2022 Oct; 36(20):5181-5188. doi:
10.1080/14786419.2021.1922406. [PMID: 33960216] - Nana Saeki, Haruna Tamano, Azusa Takeuchi, Misa Katahira, Ryusuke Nishio, Haruna Tamura, Atsushi Takeda. Heated Leaf Extract of Coriandrum sativum L. Protects Nigral Dopaminergic Degeneration in Rats.
Plant foods for human nutrition (Dordrecht, Netherlands).
2022 Sep; 77(3):455-459. doi:
10.1007/s11130-022-00999-8. [PMID: 35922685] - Francesca Palese, Silvia Pontis, Natalia Realini, Alexa Torrens, Faizy Ahmed, Francesca Assogna, Clelia Pellicano, Paola Bossù, Gianfranco Spalletta, Kim Green, Daniele Piomelli. Targeting NAAA counters dopamine neuron loss and symptom progression in mouse models of parkinsonism.
Pharmacological research.
2022 08; 182(?):106338. doi:
10.1016/j.phrs.2022.106338. [PMID: 35781057] - Jesus Alarcon-Gil, Ana Sierra-Magro, Jose A Morales-Garcia, Marina Sanz-SanCristobal, Sandra Alonso-Gil, Marta Cortes-Canteli, Mireia Niso-Santano, Guadalupe Martínez-Chacón, Jose M Fuentes, Angel Santos, Ana Perez-Castillo. Neuroprotective and Anti-Inflammatory Effects of Linoleic Acid in Models of Parkinson's Disease: The Implication of Lipid Droplets and Lipophagy.
Cells.
2022 07; 11(15):. doi:
10.3390/cells11152297. [PMID: 35892594] - Yiran Sun, Libo He, Wang Wang, Zhishen Xie, Xiaowei Zhang, Pan Wang, Lan Wang, Chenchen Yan, Zhiwen Liu, Jie Zhao, Zhenghao Cui, Yida Wang, Lin Tang, Zhenqiang Zhang. Activation of Atg7-dependent autophagy by a novel inhibitor of the Keap1-Nrf2 protein-protein interaction from Penthorum chinense Pursh. attenuates 6-hydroxydopamine-induced ferroptosis in zebrafish and dopaminergic neurons.
Food & function.
2022 Jul; 13(14):7885-7900. doi:
10.1039/d2fo00357k. [PMID: 35776077] - Samantha Smith, Jordan Sergio, Michael Coyle, Kayla Elder, Ashley Centner, Sophie Cohen, Michelle Terry, Natalie Lipari, John Glinski, Emily Wheelis, Carla Budrow, Christopher Bishop. The effects of Vilazodone, YL-0919 and Vortioxetine in hemiparkinsonian rats.
Psychopharmacology.
2022 Jul; 239(7):2119-2132. doi:
10.1007/s00213-022-06078-9. [PMID: 35275226] - Pavlína Hašková, Lenka Applová, Hana Jansová, Pavel Homola, Katherine J Franz, Kateřina Vávrová, Jaroslav Roh, Tomáš Šimůnek. Examination of diverse iron-chelating agents for the protection of differentiated PC12 cells against oxidative injury induced by 6-hydroxydopamine and dopamine.
Scientific reports.
2022 06; 12(1):9765. doi:
10.1038/s41598-022-13554-x. [PMID: 35697900] - Hossein Piri, Sahar Sharifi, Sepideh Nigjeh, Hashem Haghdoost-Yazdi. Dopaminergic neuronal death in the substantia nigra associates with change in serum levels of TNF-α and IL-1β; evidence from early experimental model of Parkinson's disease.
Neurological research.
2022 Jun; 44(6):544-553. doi:
10.1080/01616412.2021.2024726. [PMID: 34986749] - Shivangi Gupta, Virendra Tiwari, Priya Tiwari, Parul, Akanksha Mishra, Kashif Hanif, Shubha Shukla. Angiotensin-Converting Enzyme 2 Activation Mitigates Behavioral Deficits and Neuroinflammatory Burden in 6-OHDA Induced Experimental Models of Parkinson's Disease.
ACS chemical neuroscience.
2022 05; 13(10):1491-1504. doi:
10.1021/acschemneuro.1c00797. [PMID: 35533351] - Maria Lazarova, Lyubka Tancheva, Radoslav Chayrov, Elina Tzvetanova, Albena Alexandrova, Andrey Popatanasov, Diamara Uzunova, Miroslava Stefanova, Ivanka Stankova, Reni Kalfin. Tyrosinyl-amantadine: A New Amantadine Derivative With an Ameliorative Effect in a 6-OHDA Experimental Model of Parkinson's Disease in Rats.
Journal of molecular neuroscience : MN.
2022 Apr; 72(4):900-909. doi:
10.1007/s12031-021-01964-x. [PMID: 35091981] - Rubén Estrada-Valencia, María Ester Hurtado-Díaz, Edgar Rangel-López, Socorro Retana-Márquez, Isaac Túnez, Alexey Tinkov, Cimen Karasu, Beatriz Ferrer, José Pedraza-Chaverri, Michael Aschner, Abel Santamaría. Alpha-Mangostin Alleviates the Short-term 6-Hydroxydopamine-Induced Neurotoxicity and Oxidative Damage in Rat Cortical Slices and in Caenorhabditis elegans.
Neurotoxicity research.
2022 Apr; 40(2):573-584. doi:
10.1007/s12640-022-00493-8. [PMID: 35380367] - Yuening Luo, Siqi Zhou, Reiko Takeda, Kazuma Okazaki, Marie Sekita, Kazuichi Sakamoto. Protective Effect of Amber Extract on Human Dopaminergic Cells against 6-Hydroxydopamine-Induced Neurotoxicity.
Molecules (Basel, Switzerland).
2022 Mar; 27(6):. doi:
10.3390/molecules27061817. [PMID: 35335178] - Esther Gramage, Jorge Sáiz, Rosalía Fernández-Calle, Yasmina B Martín, María Uribarri, Marcel Ferrer-Alcón, Coral Barbas, Gonzalo Herradón. Metabolomics and biochemical alterations caused by pleiotrophin in the 6-hydroxydopamine mouse model of Parkinson's disease.
Scientific reports.
2022 03; 12(1):3577. doi:
10.1038/s41598-022-07419-6. [PMID: 35246557] - Farajollah Jafari, Mahdi Goudarzvand, Ramin Hajikhani, Mostafa Qorbani, Jalal Solati. Pycnogenol ameliorates motor function and gene expressions of NF-ƙB and Nrf2 in a 6-hydroxydopamine-induced experimental model of Parkinson's disease in male NMRI mice.
Naunyn-Schmiedeberg's archives of pharmacology.
2022 03; 395(3):305-313. doi:
10.1007/s00210-022-02201-x. [PMID: 35024909] - Peyman Sahbaie, Wen-Wu Li, Tian-Zhi Guo, Xiao-You Shi, Wade S Kingery, J David Clark. Autonomic Regulation of Nociceptive and Immunologic Changes in a Mouse Model of Complex Regional Pain Syndrome.
The journal of pain.
2022 Mar; 23(3):472-486. doi:
10.1016/j.jpain.2021.09.009. [PMID: 34699985] - Saeideh Nourmohammadi, Sanaz Yousefi, Mahboubeh Manouchehrabadi, Mona Farhadi, Zahra Azizi, Anahita Torkaman-Boutorabi. Thymol protects against 6-hydroxydopamine-induced neurotoxicity in in vivo and in vitro model of Parkinson's disease via inhibiting oxidative stress.
BMC complementary medicine and therapies.
2022 Feb; 22(1):40. doi:
10.1186/s12906-022-03524-1. [PMID: 35144603] - Ali Sarbazi-Golezari, Hashem Haghdoost-Yazdi. Chronic and progressive dopaminergic neuronal death in substantia nigra associates with a decrease in serum levels of glucose and free fatty acids, the role of interlokin-1 beta.
Metabolic brain disease.
2022 02; 37(2):373-381. doi:
10.1007/s11011-021-00868-4. [PMID: 34767157] - Kasthuri Bai Magalingam, Sushela Devi Somanath, Shadab Md, Nagaraja Haleagrahara, Ju-Yen Fu, Kanga Rani Selvaduray, Ammu Kutty Radhakrishnan. Tocotrienols protect differentiated SH-SY5Y human neuroblastoma cells against 6-hydroxydopamine-induced cytotoxicity by ameliorating dopamine biosynthesis and dopamine receptor D2 gene expression.
Nutrition research (New York, N.Y.).
2022 02; 98(?):27-40. doi:
10.1016/j.nutres.2021.09.003. [PMID: 35065349] - Ana Virel, Jarkko Johansson, Jan Axelsson, Madelene Ericsson, Rutger Laterveer, Mattias Ögren, Greger Orädd, Susanna Jakobson Mo, Sara Af Bjerkén. N-acetylcysteine decreases dopamine transporter availability in the non-lesioned striatum of the 6-OHDA hemiparkinsonian rat.
Neuroscience letters.
2022 01; 770(?):136420. doi:
10.1016/j.neulet.2021.136420. [PMID: 34958912] - Zifeng Huang, Jiajun Han, Peipei Wu, Chunxiao Wu, Yaohua Fan, Lijun Zhao, Xiaoqian Hao, Dongfeng Chen, Meiling Zhu. Sorting Nexin 5 Plays an Important Role in Promoting Ferroptosis in Parkinson's Disease.
Oxidative medicine and cellular longevity.
2022; 2022(?):5463134. doi:
10.1155/2022/5463134. [PMID: 35571244] - Yaohua Fan, Mengzhu Li, Chunxiao Wu, Yubiao Wu, Jiajun Han, Peipei Wu, Zifeng Huang, Qizhang Wang, Lijun Zhao, Dongfeng Chen, Meiling Zhu. Chronic Cerebral Hypoperfusion Aggravates Parkinson's Disease Dementia-Like Symptoms and Pathology in 6-OHDA-Lesioned Rat through Interfering with Sphingolipid Metabolism.
Oxidative medicine and cellular longevity.
2022; 2022(?):5392966. doi:
10.1155/2022/5392966. [PMID: 35979400] - B S Cagle, M L Sturgeon, J B O'Brien, J C Wilkinson, R A Cornell, D L Roman, J A Doorn. Stable expression of the human dopamine transporter in N27 cells as an in vitro model for dopamine cell trafficking and metabolism.
Toxicology in vitro : an international journal published in association with BIBRA.
2021 Oct; 76(?):105210. doi:
10.1016/j.tiv.2021.105210. [PMID: 34252731] - Qian Xu, Wei Qin, Fang-Zhen Wu, Yao Lin, Li-Ting Hong, Dan Chen, Xue-Feng Hu, Jing Cai. Effect of Roucongrong (Herba Cistanches Deserticolae) decoction on the substantia nigra through Wnt/β-catenin signaling pathway in rats with Parkinson's disease induced by 6-hydroxydopamine hydrochloride.
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan.
2021 10; 41(5):762-770. doi:
10.19852/j.cnki.jtcm.2021.05.010. [PMID: 34708635] - Ashish Singh, Arun Kumar Yadawa, Swati Chaturvedi, M Wahajuddin, Amit Mishra, Sarika Singh. Mechanism for antiParkinsonian effect of resveratrol: Involvement of transporters, synaptic proteins, dendrite arborization, biochemical alterations, ER stress and apoptosis.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2021 Sep; 155(?):112433. doi:
10.1016/j.fct.2021.112433. [PMID: 34302886] - Huan Li, Joonki Kim, Huynh Nguyen Khanh Tran, Chang Hwan Lee, Jonghyun Hur, Min Cheol Kim, Hyun Ok Yang. Extract of Polygala tenuifolia, Angelica tenuissima, and Dimocarpus longan Reduces Behavioral Defect and Enhances Autophagy in Experimental Models of Parkinson's Disease.
Neuromolecular medicine.
2021 09; 23(3):428-443. doi:
10.1007/s12017-020-08643-x. [PMID: 33432492] - Maria Dąbkowska, Zofia Ulańczyk, Karolina Łuczkowska, Dorota Rogińska, Anna Sobuś, Monika Wasilewska, Maria Olszewska, Katarzyna Jakubowska, Bogusław Machaliński. The role of the electrokinetic charge of neurotrophis-based nanocarriers: protein distribution, toxicity, and oxidative stress in in vitro setting.
Journal of nanobiotechnology.
2021 Aug; 19(1):258. doi:
10.1186/s12951-021-00984-4. [PMID: 34454520] - Yanan Hou, Shoujiao Peng, Zilong Song, Feifei Bai, Xinming Li, Jianguo Fang. Oat polyphenol avenanthramide-2c confers protection from oxidative stress by regulating the Nrf2-ARE signaling pathway in PC12 cells.
Archives of biochemistry and biophysics.
2021 07; 706(?):108857. doi:
10.1016/j.abb.2021.108857. [PMID: 33781769] - Gholamreza Komeili, Elham Haghparast, Vahid Sheibani. Marijuana improved motor impairments and changes in synaptic plasticity-related molecules in the striatum in 6-OHDA-treated rats.
Behavioural brain research.
2021 07; 410(?):113342. doi:
10.1016/j.bbr.2021.113342. [PMID: 33961911] - Zahra Tayarani-Najaran, Elham Hadipour, Seyed Mahdi Seyed Mousavi, Seyed Ahmad Emami, Leila Mohtashami, Behjat Javadi. Protective effects of Lavandula stoechas L. methanol extract against 6-OHDA-induced apoptosis in PC12 cells.
Journal of ethnopharmacology.
2021 Jun; 273(?):114023. doi:
10.1016/j.jep.2021.114023. [PMID: 33716081] - Maryam Bigham, Abbas Mohammadipour, Mahmoud Hosseini, Amir Mohammad Malvandi, Alireza Ebrahimzadeh-Bideskan. Neuroprotective effects of garlic extract on dopaminergic neurons of substantia nigra in a rat model of Parkinson's disease: motor and non-motor outcomes.
Metabolic brain disease.
2021 06; 36(5):927-937. doi:
10.1007/s11011-021-00705-8. [PMID: 33656625] - D P Ferrari, M Bortolanza, E A Del Bel. Interferon-γ Involvement in the Neuroinflammation Associated with Parkinson's Disease and L-DOPA-Induced Dyskinesia.
Neurotoxicity research.
2021 Jun; 39(3):705-719. doi:
10.1007/s12640-021-00345-x. [PMID: 33687725] - Talita Tuon, Sandra S Meirelles, Airam B de Moura, Thayse Rosa, Laura A Borba, Maria Eduarda M Botelho, Helena M Abelaira, Gisiane B de Mathia, Lucineia G Danielski, Maria Eduarda Fileti, Fabricia Petronilho, Zuleide Maria Ignácio, João Quevedo, Gislaine Z Réus. Behavior and oxidative stress parameters in rats subjected to the animal's models induced by chronic mild stress and 6-hydroxydopamine.
Behavioural brain research.
2021 05; 406(?):113226. doi:
10.1016/j.bbr.2021.113226. [PMID: 33684423] - Jui-Chih Chang, Yi-Chun Chao, Huei-Shin Chang, Yu-Ling Wu, Hui-Ju Chang, Yong-Shiou Lin, Wen-Ling Cheng, Ta-Tsung Lin, Chin-San Liu. Intranasal delivery of mitochondria for treatment of Parkinson's Disease model rats lesioned with 6-hydroxydopamine.
Scientific reports.
2021 05; 11(1):10597. doi:
10.1038/s41598-021-90094-w. [PMID: 34011937] - Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
2021 04; 35(4):109040. doi:
10.1016/j.celrep.2021.109040. [PMID: 33910017] - Wen-Wen Wang, Ruiyu Han, Hai-Jun He, Jia Li, Si-Yan Chen, Yingying Gu, Chenglong Xie. Administration of quercetin improves mitochondria quality control and protects the neurons in 6-OHDA-lesioned Parkinson's disease models.
Aging.
2021 04; 13(8):11738-11751. doi:
10.18632/aging.202868. [PMID: 33878030] - Patrick T Rudak, Joshua Choi, Katie M Parkins, Kelly L Summers, Dwayne N Jackson, Paula J Foster, Anton I Skaro, Ken Leslie, Vivian C McAlister, Vijay K Kuchroo, Wataru Inoue, Olivier Lantz, S M Mansour Haeryfar. Chronic stress physically spares but functionally impairs innate-like invariant T cells.
Cell reports.
2021 04; 35(2):108979. doi:
10.1016/j.celrep.2021.108979. [PMID: 33852855] - Rachel M McQuade, Lewis M Singleton, Hongyi Wu, Sophie Lee, Remy Constable, Madeleine Di Natale, Mitchell T Ringuet, Joel P Berger, Jessica Kauhausen, Clare L Parish, David I Finkelstein, John B Furness, Shanti Diwakarla. The association of enteric neuropathy with gut phenotypes in acute and progressive models of Parkinson's disease.
Scientific reports.
2021 04; 11(1):7934. doi:
10.1038/s41598-021-86917-5. [PMID: 33846426] - Xinrong Li, Wenwen Si, Zhan Li, Ye Tian, Xuelei Liu, Shanyu Ye, Zifeng Huang, Yichun Ji, Caiping Zhao, Xiaoqian Hao, Dongfeng Chen, Meiling Zhu. miR‑335 promotes ferroptosis by targeting ferritin heavy chain 1 in in vivo and in vitro models of Parkinson's disease.
International journal of molecular medicine.
2021 04; 47(4):. doi:
10.3892/ijmm.2021.4894. [PMID: 33649797] - Rafael Rivas-Santisteban, Jaume Lillo, Ana Muñoz, Ana I Rodríguez-Pérez, José Luís Labandeira-García, Gemma Navarro, Rafael Franco. Novel Interactions Involving the Mas Receptor Show Potential of the Renin-Angiotensin system in the Regulation of Microglia Activation: Altered Expression in Parkinsonism and Dyskinesia.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics.
2021 04; 18(2):998-1016. doi:
10.1007/s13311-020-00986-4. [PMID: 33474655] - Li Liu, Yi Chen, Rui-Feng Zeng, Yun Liu, Sai-Sai Xie, Jin-Shuai Lan, Yue Ding, Yi-Ting Yang, Jun Yang, Tong Zhang. Design and synthesis of novel 3,4-dihydrocoumarins as potent and selective monoamine oxidase-B inhibitors with the neuroprotection against Parkinson's disease.
Bioorganic chemistry.
2021 04; 109(?):104685. doi:
10.1016/j.bioorg.2021.104685. [PMID: 33640631] - Qinge Ma, Rongrui Wei, Xiaodong Zhang, Zhipei Sang, Jianghong Dong. Structural elucidation and neuroprotective activities of lignans from the flower buds of Magnolia biondii Pamp.
Zeitschrift fur Naturforschung. C, Journal of biosciences.
2021 Mar; 76(3-4):147-152. doi:
10.1515/znc-2020-0100. [PMID: 33098637] - Esmail Alipour Nosrani, Omid Reza Tamtaji, Zahra Alibolandi, Parichehr Sarkar, Mohsen Ghazanfari, Abolfazl Azami Tameh, Mohsen Taghizadeh, Zarrin Banikazemi, Razie Hadavi, Mojtaba Naderi Taheri. Neuroprotective effects of probiotics bacteria on animal model of Parkinson's disease induced by 6-hydroxydopamine: A behavioral, biochemical, and histological study.
Journal of immunoassay & immunochemistry.
2021 Mar; 42(2):106-120. doi:
10.1080/15321819.2020.1833917. [PMID: 33078659] - Hao Zhang, Jinlu Xie, Yaqiong Li, Huimin Liu, Chuanguo Liu, Dongfang Kan, Xiwen Geng, Sheng Wei. Levodopa affects spike and local field synchronisation in the pedunculopontine nucleus of a rat model of Parkinson's disease.
Aging.
2021 02; 13(5):7314-7329. doi:
10.18632/aging.202585. [PMID: 33639616] - Ewelina Kozioł, Krystyna Skalicka-Woźniak, Agnieszka Michalak, Katarzyna Kaszubska, Barbara Budzyńska. Xanthotoxin reverses Parkinson's disease-like symptoms in zebrafish larvae and mice models: a comparative study.
Pharmacological reports : PR.
2021 Feb; 73(1):122-129. doi:
10.1007/s43440-020-00136-9. [PMID: 32700246] - Louise Oliveira Fiametti, Claudia Neves Correa, Leandro Mantovani de Castro. Peptide Profile of Zebrafish Brain in a 6-OHDA-Induced Parkinson Model.
Zebrafish.
2021 02; 18(1):55-65. doi:
10.1089/zeb.2020.1945. [PMID: 33570475] - Nida Nehal, Bushra Nabi, Saleha Rehman, Ankita Pathak, Ashif Iqubal, Saif Ahmad Khan, M Shahar Yar, Suhel Parvez, Sanjula Baboota, Javed Ali. Chitosan coated synergistically engineered nanoemulsion of Ropinirole and nigella oil in the management of Parkinson's disease: Formulation perspective and In vitro and In vivo assessment.
International journal of biological macromolecules.
2021 Jan; 167(?):605-619. doi:
10.1016/j.ijbiomac.2020.11.207. [PMID: 33278450] - Hiroki Umemoto, Saika Yasugi, Shinji Tsuda, Minoru Yoda, Takashi Ishiguro, Naoko Kaba, Tatsuki Itoh. Protective Effect of Nervonic Acid Against 6-Hydroxydopamine-Induced Oxidative Stress in PC-12 Cells.
Journal of oleo science.
2021; 70(1):95-102. doi:
10.5650/jos.ess20262. [PMID: 33431776] - Yu-Ting Liao, Huey-Pin Tsai, Shih-Min Wang, Shun-Hua Chen. Clinical and Immune Responses of Peripheral Chemical Sympathectomy in Enterovirus 71 Infection.
Frontiers in immunology.
2021; 12(?):700903. doi:
10.3389/fimmu.2021.700903. [PMID: 34566960] - Hongli Li, Yaru Feng, Ziyu Chen, Xi Jiang, Zhenyu Zhou, Jinfeng Yuan, Fei Li, Yu Zhang, Xingxu Huang, Shengjie Fan, Xiaojun Wu, Cheng Huang. Pepper component 7-ethoxy-4-methylcoumarin, a novel dopamine D2 receptor agonist, ameliorates experimental Parkinson's disease in mice and Caenorhabditis elegans.
Pharmacological research.
2021 01; 163(?):105220. doi:
10.1016/j.phrs.2020.105220. [PMID: 33007422] - Graziella R Molska, Lyvia Izaura G Paula-Freire, Marna E Sakalem, Daniele O Köhn, Giuseppina Negri, Elisaldo A Carlini, Fúlvio R Mendes. Green coffee extract attenuates Parkinson's-related behaviors in animal models.
Anais da Academia Brasileira de Ciencias.
2021; 93(suppl 4):e20210481. doi:
10.1590/0001-3765202120210481. [PMID: 34730624] - Li-Ying Guo, Feng-Lei Shi, Meng Li, Jin-Hao Sun, Chuan-Gang Li, Zeng-Xun Liu. Astragalus protects PC12 cells from 6-hydroxydopamine-induced neuronal damage: A serum pharmacological study.
The Chinese journal of physiology.
2021 Jan; 64(1):24-31. doi:
10.4103/cjp.cjp_50_20. [PMID: 33642341] - Yanyan Luo, Yunyao Jiang, Yang He, Ting Shen, Lilian Ji, Fu Li, Weicheng Hu. Vina-Ginsenoside R4 from Panax ginseng Leaves Alleviates 6-OHDA-Induced Neurotoxicity in PC12 Cells Via the PI3K/Akt/GSK-3β Signaling Pathway.
Journal of agricultural and food chemistry.
2020 Dec; 68(51):15239-15248. doi:
10.1021/acs.jafc.0c06474. [PMID: 33290066] - Rasool Haddadi, Shahla Eyvari-Brooshghalan, Alireza Mohajjel Nayebi, Mohammadmahdi Sabahi, Sara Ami Ahmadi. Neuronal degeneration and oxidative stress in the SNc of 6-OHDA intoxicated rats; improving role of silymarin long-term treatment.
Naunyn-Schmiedeberg's archives of pharmacology.
2020 12; 393(12):2427-2437. doi:
10.1007/s00210-020-01954-7. [PMID: 32715318] - Xiaomei Yang, Yun Li, Lin Chen, Mingguo Xu, Jianbo Wu, Peng Zhang, Deon Nel, Baozhu Sun. Protective effect of hydroxysafflor yellow A on dopaminergic neurons against 6-hydroxydopamine, activating anti-apoptotic and anti-neuroinflammatory pathways.
Pharmaceutical biology.
2020 Dec; 58(1):686-694. doi:
10.1080/13880209.2020.1784237. [PMID: 32658590] - Hui Lei, Rutong Ren, Yi Sun, Ke Zhang, Xin Zhao, Nuramatjan Ablat, Xiaoping Pu. Neuroprotective Effects of Safflower Flavonoid Extract in 6-Hydroxydopamine-Induced Model of Parkinson's Disease May Be Related to its Anti-Inflammatory Action.
Molecules (Basel, Switzerland).
2020 Nov; 25(21):. doi:
10.3390/molecules25215206. [PMID: 33182332] - Yiran Sun, Libo He, Taoyu Wang, Wan Hua, Huan Qin, Jingjin Wang, Li Wang, Wanqin Gu, Tingting Li, Na Li, Xinanbei Liu, Fang Chen, Lin Tang. Activation of p62-Keap1-Nrf2 Pathway Protects 6-Hydroxydopamine-Induced Ferroptosis in Dopaminergic Cells.
Molecular neurobiology.
2020 Nov; 57(11):4628-4641. doi:
10.1007/s12035-020-02049-3. [PMID: 32770451] - Blenda Hyedra de Campos, Lorena de Jager, Gabriela Souza Reginato, Rito Santo Pereira, Carlos César Crestani, Phileno Pinge-Filho, Marli Cardoso Martins-Pinge. Cardiovascular evaluation of female rats with 6-OHDA-induced parkinsonism: Possible protection by ovarian hormones and participation of nitric oxide.
Life sciences.
2020 Oct; 259(?):118259. doi:
10.1016/j.lfs.2020.118259. [PMID: 32795538] - Concepció Marin, Mercè Bonastre, Mireya Fuentes, Joaquim Mullol. Lack of correlation between dyskinesia and pallidal serotonin transporter expression-induced by L-Dopa and Pramipexole in hemiparkinsonian rats.
Pharmacology, biochemistry, and behavior.
2020 10; 197(?):173012. doi:
10.1016/j.pbb.2020.173012. [PMID: 32750392] - Wen-Jun Duan, Lei Liang, Ming-Hai Pan, Dan-Hua Lu, Ting-Mei Wang, Shan-Bing Li, Han-Bing Zhong, Xuan-Jun Yang, Yan Cheng, Bo Liu, Wei-Xi Li, Hiroshi Kurihara, Wei Bi, Yi-Fang Li, Rong-Rong He. Theacrine, a purine alkaloid from kucha, protects against Parkinson's disease through SIRT3 activation.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2020 Oct; 77(?):153281. doi:
10.1016/j.phymed.2020.153281. [PMID: 32707370] - Ye Tian, Juan Lu, Xiaoqian Hao, Hang Li, Guiyu Zhang, Xuelei Liu, Xinrong Li, Caiping Zhao, Weihong Kuang, Dongfeng Chen, Meiling Zhu. FTH1 Inhibits Ferroptosis Through Ferritinophagy in the 6-OHDA Model of Parkinson's Disease.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics.
2020 10; 17(4):1796-1812. doi:
10.1007/s13311-020-00929-z. [PMID: 32959272] - Carlos Franciney Moreira Vasconcelos, Nívea Maria da Cunha Ferreira, Nayanne Hardy Lima Pontes, Thomas Dominik de Sousa Dos Reis, Ricardo Basto Souza, Francisco Eduardo Aragão Catunda Junior, Lissiana Magna Vasconcelos Aguiar, Rodrigo Maranguape Silva da Cunha. Eugenol and its association with levodopa in 6-hydroxydopamine-induced hemiparkinsonian rats: Behavioural and neurochemical alterations.
Basic & clinical pharmacology & toxicology.
2020 Oct; 127(4):287-302. doi:
10.1111/bcpt.13425. [PMID: 32353201] - Concepció Marin, Mercè Bonastre, Mireya Fuentes, Joaquim Mullol. Globus pallidus, but not entopeduncular nucleus, 6-OHDA-induced lesion attenuates L-Dopa-induced dyskinesia in the rat model of Parkinson's disease.
Pharmacology, biochemistry, and behavior.
2020 10; 197(?):173013. doi:
10.1016/j.pbb.2020.173013. [PMID: 32758524] - Andréia Mayer Biolchi, Danilo Gustavo Rodrigues de Oliveira, Henrique de Oliveira Amaral, Gabriel Avohay Alves Campos, Jacqueline Coimbra Gonçalves, Adolfo Carlos Barros de Souza, Marcos Robalinho Lima, Luciano Paulino Silva, Márcia Renata Mortari. Fraternine, a Novel Wasp Peptide, Protects against Motor Impairments in 6-OHDA Model of Parkinsonism.
Toxins.
2020 08; 12(9):. doi:
10.3390/toxins12090550. [PMID: 32867207] - Julian L Goggi, Lifeng Qiu, Mei Chih Liao, Shivashankar Khanapur, Lingfan Jiang, Ramasamy Boominathan, Siddesh V Hartimath, Peter Cheng, Fui Fong Yong, Vanessa Soh, Xiaozhou Deng, Youshan Melissa Lin, Anna Haslop, Peng Wen Tan, Xiaoxia Zeng, Jolene W L Lee, Zhiwei Zhang, Pragalath Sadasivam, Eng King Tan, Sajinder K Luthra, William D Shingleton, Steve K W Oh, Li Zeng, Edward G Robins. Dopamine transporter neuroimaging accurately assesses the maturation of dopamine neurons in a preclinical model of Parkinson's disease.
Stem cell research & therapy.
2020 08; 11(1):347. doi:
10.1186/s13287-020-01868-4. [PMID: 32771055] - Jun Meng, Huamei Chen, Qin Lv, Xiaodan Luo, Kun Yang. The Release of Norepinephrine in C57BL/6J Mice Treated with 6-Hydroxydopamine (6-OHDA) is Associated with Translocations in Enteric Escherichia coli via the QseC Histidine Kinase Receptor.
Medical science monitor : international medical journal of experimental and clinical research.
2020 Aug; 26(?):e922986. doi:
10.12659/msm.922986. [PMID: 32764532] - Wenhao Li, Han Gao, Wentao Li. Effects of Combined Bushen Zhichan Recipe and Levodopa in a Rodent Model of Parkinson Disease: Potential Mechanisms.
Medical science monitor : international medical journal of experimental and clinical research.
2020 Jun; 26(?):e922345. doi:
10.12659/msm.922345. [PMID: 32555131] - Albert Katchborian-Neto, Wanderleya T Santos, Karen J Nicácio, José O A Corrêa, Michael Murgu, Thaís M M Martins, Dawidson A Gomes, Alfredo M Goes, Marisi G Soares, Danielle F Dias, Daniela A Chagas-Paula, Ana C C Paula. Neuroprotective potential of Ayahuasca and untargeted metabolomics analyses: applicability to Parkinson's disease.
Journal of ethnopharmacology.
2020 Jun; 255(?):112743. doi:
10.1016/j.jep.2020.112743. [PMID: 32171895] - Jalles Dantas de Lucena, Carlos Vinicius Jataí Gadelha-Filho, Roberta Oliveira da Costa, Dayane Pessoa de Araújo, Francisco Arnaldo Viana Lima, Kelly Rose Tavares Neves, Glauce Socorro de Barros Viana. L-linalool exerts a neuroprotective action on hemiparkinsonian rats.
Naunyn-Schmiedeberg's archives of pharmacology.
2020 06; 393(6):1077-1088. doi:
10.1007/s00210-019-01793-1. [PMID: 31938809] - Rongfei Wang, Ming Shao. L-DOPA-elicited abnormal involuntary movements in the rats damaged severely in substantia nigra by 6-hydroxydopamine.
Annals of palliative medicine.
2020 May; 9(3):947-956. doi:
10.21037/apm.2020.03.32. [PMID: 32279520] - Elham Ramazani, Mahdi YazdFazeli, Seyed Ahmad Emami, Leila Mohtashami, Behjat Javadi, Javad Asili, Zahra Tayarani-Najaran. Protective effects of Cinnamomum verum, Cinnamomum cassia and cinnamaldehyde against 6-OHDA-induced apoptosis in PC12 cells.
Molecular biology reports.
2020 Apr; 47(4):2437-2445. doi:
10.1007/s11033-020-05284-y. [PMID: 32166553] - Laya Ghahari, Manouchehr Safari, Khojaste Rahimi Jaberi, Behnaz Jafari, Katayoun Safari, Mahmoodreza Madadian. Mesenchymal Stem Cells with Granulocyte Colony-Stimulating Factor Reduce Stress Oxidative Factors in Parkinson's Disease.
Iranian biomedical journal.
2020 03; 24(2):89-98. doi:
10.29252/ibj.24.2.89. [PMID: 31677610] - Helena Xicoy, Jos F Brouwers, Oleksandra Kalnytska, Bé Wieringa, Gerard J M Martens. Lipid Analysis of the 6-Hydroxydopamine-Treated SH-SY5Y Cell Model for Parkinson's Disease.
Molecular neurobiology.
2020 Feb; 57(2):848-859. doi:
10.1007/s12035-019-01733-3. [PMID: 31493240] - Gyeong Hee Lee, Won Jin Lee, Jinwoo Hur, Eunsu Kim, Hyuk Gyoon Lee, Han Geuk Seo. Ginsenoside Re Mitigates 6-Hydroxydopamine-Induced Oxidative Stress through Upregulation of GPX4.
Molecules (Basel, Switzerland).
2020 Jan; 25(1):. doi:
10.3390/molecules25010188. [PMID: 31906464] - Mahdi Eskandarian Boroujeni, Abbas Aliaghaei, Nader Maghsoudi, Mossa Gardaneh. Complementation of dopaminergic signaling by Pitx3-GDNF synergy induces dopamine secretion by multipotent Ntera2 cells.
Journal of cellular biochemistry.
2020 01; 121(1):200-212. doi:
10.1002/jcb.29109. [PMID: 31310388] - Karen P Briski, Santosh K Mandal. Hindbrain metabolic deficiency regulates ventromedial hypothalamic nucleus glycogen metabolism and glucose‑regulatory signaling.
Acta neurobiologiae experimentalis.
2020; 80(1):57-65. doi:
10.21307/ane-2020-006. [PMID: 32214275] - Ioannis Mantas, Yunting Yang, Clotilde Mannoury-la-Cour, Mark J Millan, Xiaoqun Zhang, Per Svenningsson. Genetic deletion of GPR88 enhances the locomotor response to L-DOPA in experimental parkinsonism while counteracting the induction of dyskinesia.
Neuropharmacology.
2020 01; 162(?):107829. doi:
10.1016/j.neuropharm.2019.107829. [PMID: 31666199]