Misonidazole (BioDeep_00000858650)
代谢物信息卡片
Misonidazole
化学式: C7H11N3O4 (201.0749526)
中文名称: 米索硝唑
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: COCC(CN1C=CN=C1[N+](=O)[O-])O
InChI: InChI=1S/C7H11N3O4/c1-14-5-6(11)4-9-3-2-8-7(9)10(12)13/h2-3,6,11H,4-5H2,1H3
描述信息
D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000981 - Antiprotozoal Agents
C274 - Antineoplastic Agent > C798 - Radiosensitizing Agent
D011838 - Radiation-Sensitizing Agents
D000970 - Antineoplastic Agents
同义名列表
1 个代谢物同义名
数据库引用编号
7 个数据库交叉引用编号
- KEGGdrug: D05052
- PubChem: 26105
- DrugBank: DB11716
- ChEMBL: CHEMBL42161
- MeSH: Misonidazole
- CAS: 95120-44-8
- CAS: 13551-87-6
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Alexander Rühle, Nicole Wiedenmann, Jamina T Fennell, Michael Mix, Juri Ruf, Raluca Stoian, Andreas R Thomsen, Peter Vaupel, Dimos Baltas, Anca-L Grosu, Nils H Nicolay. Interleukin-6 as surrogate marker for imaging-based hypoxia dynamics in patients with head-and-neck cancers undergoing definitive chemoradiation-results from a prospective pilot trial.
European journal of nuclear medicine and molecular imaging.
2022 04; 49(5):1650-1660. doi:
10.1007/s00259-021-05602-x. [PMID: 34773163] - S T Lee, V Muralidharan, N Tebbutt, P Wong, C Fang, Z Liu, H Gan, J Sachinidis, K Pathmaraj, C Christophi, A M Scott. Prevalence of hypoxia and correlation with glycolytic metabolism and angiogenic biomarkers in metastatic colorectal carcinoma.
European journal of nuclear medicine and molecular imaging.
2021 05; 48(5):1585-1592. doi:
10.1007/s00259-020-05074-5. [PMID: 33125527] - Philipp Guenthoer, Kerstin Fuchs, Gerald Reischl, Leticia Quintanilla-Martinez, Irene Gonzalez-Menendez, Stefan Laufer, Bernd J Pichler, Manfred Kneilling. Evaluation of the therapeutic potential of the selective p38 MAPK inhibitor Skepinone-L and the dual p38/JNK 3 inhibitor LN 950 in experimental K/BxN serum transfer arthritis.
Inflammopharmacology.
2019 Dec; 27(6):1217-1227. doi:
10.1007/s10787-019-00593-6. [PMID: 31037574] - Hao Jiang, Rongjun Zhang, Huijie Jiang, Mingyu Zhang, Wei Guo, Guanglong Feng, Wenbin Pan, Hailong Xu, Song Wang. Evaluation of [18F]FDG/[18F]FLT/[18F]FMISO-based micro-positron emission tomography in detection of liver metastasis in human colorectal cancer.
Nuclear medicine and biology.
2019 May; 72-73(?):36-44. doi:
10.1016/j.nucmedbio.2019.07.004. [PMID: 31330410] - Ming-Yu Zhang, Rong-Jun Zhang, Hui-Jie Jiang, Hao Jiang, Hai-Long Xu, Wen-Bin Pan, Yi-Qiao Wang, Xin Li. 18F-fluoromisonidazole positron emission tomography may be applicable in the evaluation of colorectal cancer liver metastasis.
Hepatobiliary & pancreatic diseases international : HBPD INT.
2019 Apr; 18(2):164-172. doi:
10.1016/j.hbpd.2019.02.008. [PMID: 30850340] - Mingyu Zhang, Huijie Jiang, Rongjun Zhang, Hailong Xu, Hao Jiang, Wenbin Pan, Xin Li, Yiqiao Wang, Song Wang. Noninvasive evaluation of 18F-FDG/18F-FMISO-based Micro PET in monitoring hepatic metastasis of colorectal cancer.
Scientific reports.
2018 12; 8(1):17832. doi:
10.1038/s41598-018-36238-x. [PMID: 30546057] - Aya Asano, Shigeto Ueda, Ichiei Kuji, Tomohiko Yamane, Hideki Takeuchi, Eiko Hirokawa, Ikuko Sugitani, Hiroko Shimada, Takahiro Hasebe, Akihiko Osaki, Toshiaki Saeki. Intracellular hypoxia measured by 18F-fluoromisonidazole positron emission tomography has prognostic impact in patients with estrogen receptor-positive breast cancer.
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2018 07; 20(1):78. doi:
10.1186/s13058-018-0970-6. [PMID: 30053906] - Milan Grkovski, Sally-Ann Emmas, Sean D Carlin. 18F-Fluoromisonidazole Kinetic Modeling for Characterization of Tumor Perfusion and Hypoxia in Response to Antiangiogenic Therapy.
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PloS one.
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International journal of oncology.
2012 Nov; 41(5):1593-600. doi:
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American journal of physiology. Renal physiology.
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British journal of cancer.
2009 Dec; 101(11):1860-8. doi:
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Physics in medicine and biology.
2009 May; 54(10):3083-99. doi:
10.1088/0031-9155/54/10/008. [PMID: 19420418] - HyungJoon Cho, Ellen Ackerstaff, Sean Carlin, Mihaela E Lupu, Ya Wang, Asif Rizwan, Joseph O'Donoghue, C Clifton Ling, John L Humm, Pat B Zanzonico, Jason A Koutcher. Noninvasive multimodality imaging of the tumor microenvironment: registered dynamic magnetic resonance imaging and positron emission tomography studies of a preclinical tumor model of tumor hypoxia.
Neoplasia (New York, N.Y.).
2009 Mar; 11(3):247-59, 2p following 259. doi:
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Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.
2008 Dec; 89(3):353-60. doi:
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European journal of nuclear medicine and molecular imaging.
2004 Apr; 31(4):513-20. doi:
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European journal of nuclear medicine and molecular imaging.
2004 Jan; 31(1):117-28. doi:
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2003 May; 88(9):1439-44. doi:
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2002 Dec; 43(12):1674-80. doi:
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