Cefmenoxime (BioDeep_00000858632)

   

Chemicals and Drugs Antibiotics


代谢物信息卡片


Cefmenoxime

化学式: C16H17N9O5S3 (511.0514752)
中文名称: 头孢甲肟
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CN1C(=NN=N1)SCC2=C(N3C(C(C3=O)NC(=O)C(=NOC)C4=CSC(=N4)N)SC2)C(=O)O
InChI: InChI=1S/C16H17N9O5S3/c1-24-16(20-22-23-24)33-4-6-3-31-13-9(12(27)25(13)10(6)14(28)29)19-11(26)8(21-30-2)7-5-32-15(17)18-7/h5,9,13H,3-4H2,1-2H3,(H2,17,18)(H,19,26)(H,28,29)/b21-8-/t9-,13-/m1/s1

描述信息

A third-generation cephalosporin antibiotic, bearing a 2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino group at the 7beta-position and a [(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl group at the 3-position.
J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01D - Other beta-lactam antibacterials > J01DD - Third-generation cephalosporins
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D002511 - Cephalosporins
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D047090 - beta-Lactams
S - Sensory organs > S01 - Ophthalmologicals > S01A - Antiinfectives > S01AA - Antibiotics
S - Sensory organs > S02 - Otologicals > S02A - Antiinfectives > S02AA - Antiinfectives
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D007769 - Lactams
C254 - Anti-Infective Agent > C258 - Antibiotic > C260 - Beta-Lactam Antibiotic

同义名列表

1 个代谢物同义名

Cefmenoxime



数据库引用编号

8 个数据库交叉引用编号

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代谢反应

0 个相关的代谢反应过程信息。

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  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

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文献列表

  • Fangmi Wei, Rong Zhu, Wenhui Zhao, Jing Yang, Zheng Cai, Qin Hu. Pharmacokinetics and bioequivalence studies of cefteram pivoxil in healthy Chinese volunteers. European journal of drug metabolism and pharmacokinetics. 2009 Jul; 34(3-4):157-62. doi: 10.1007/bf03191167. [PMID: 20166432]
  • Jianjun Zou, Bin Di, Chun Yong Wu, Qin Hu, Jian Hua Li, Yubing Zhu, Hongwei Fan, DaWei Xiao, Guang Ji Wang. Pharmacokinetic and bioequivalence comparison of a single 100-mg dose of cefteram pivoxil powder suspension and tablet formulations: a randomized-sequence, open-label, two-period crossover study in healthy Chinese adult male volunteers. Clinical therapeutics. 2008 Apr; 30(4):654-60. doi: 10.1016/j.clinthera.2008.04.003. [PMID: 18498914]
  • Yu-Jin Suh, Young-Mok Lee, Jeung-Hee Choi, Chang-Hee Suh, Dong-Ho Nahm, Hae-Sim Park. Heterogeneity of IgE response to cefteram pivoxil was noted in 2 patients with cefteram-induced occupational asthma. The Journal of allergy and clinical immunology. 2003 Jul; 112(1):209-10. doi: 10.1067/mai.2003.1525. [PMID: 12847502]
  • F Matsumoto, I Sakurai, M Morita, T Takahashi, N Mori, T Sugihara, A Sakai, S Yamaji, Y Akaike, K Yano. Effects of the quantity of water and milk ingested concomitantly with AS-924, a novel ester-type cephem antibiotic, on its pharmacokinetics. International journal of antimicrobial agents. 2001 Nov; 18(5):471-6. doi: 10.1016/s0924-8579(01)00447-2. [PMID: 11711263]
  • K Totsuka, K Shimizu, N Mori, T Sugihara, A Sakai, S Yamaji, Y Michisuji, Y Shinohara, A Kubo, H Tokuoka. Effect of antacid pretreatment on the pharmacokinetics of AS-924, a novel ester-type cephem antibiotic--comparison with cefteram-pivoxil. International journal of antimicrobial agents. 2001 Nov; 18(5):477-82. doi: 10.1016/s0924-8579(01)00445-9. [PMID: 11711264]
  • K Goto, M Oda, H Saitoh, M Nishida, M Takada. Effect of side chains including the N-methyl-tetrazole-thiol group of beta-lactam antibiotics on transport in cultured kidney epithelial cells LLC-PK1. Biological & pharmaceutical bulletin. 1998 Oct; 21(10):1113-6. doi: 10.1248/bpb.21.1113. [PMID: 9821822]
  • J M Hyatt, A B Luzier, A Forrest, C H Ballow, J J Schentag. Modeling the response of pneumonia to antimicrobial therapy. Antimicrobial agents and chemotherapy. 1997 Jun; 41(6):1269-74. doi: 10.1128/aac.41.6.1269. [PMID: 9174182]
  • T Dalla Costa, H Derendorf. AUIC--a general target for the optimization of dosing regimens of antibiotics?. The Annals of pharmacotherapy. 1996 Sep; 30(9):1024-8. doi: 10.1177/106002809603000919. [PMID: 8876867]
  • T Ito, N Sugiyama, M Kobayashi, K Kidouchi, T Itoh, O Uemura, K Sugiyama, H Togari. Alteration of ammonia and carnitine levels in short-term treatment with pivalic acid-containing prodrug. The Tohoku journal of experimental medicine. 1995 Jan; 175(1):43-53. doi: 10.1620/tjem.175.43. [PMID: 7610459]
  • T F Goss, A Forrest, D E Nix, C H Ballow, M C Birmingham, T J Cumbo, J J Schentag. Mathematical examination of dual individualization principles (II): The rate of bacterial eradication at the same area under the inhibitory curve is more rapid for ciprofloxacin than for cefmenoxime. The Annals of pharmacotherapy. 1994 Jul; 28(7-8):863-8. doi: 10.1177/106002809402800707. [PMID: 7949501]
  • G I Duncker, U Reich, R Krausse. Cefmenoxime in corneal organ culture. Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde. 1994; 208(5):262-6. doi: 10.1159/000310505. [PMID: 7816419]
  • J Evers, K Borner, P Koeppe. Elimination of cefmenoxime during continuous haemofiltration. European journal of clinical pharmacology. 1993; 44 Suppl 1(?):S31-2. doi: 10.1007/bf01428389. [PMID: 8486144]
  • Y Kusunoki, K Osana, H Yoshioka. [Identification of pivaloylcarnitine in urine of patients with pivoxil therapy]. No to hattatsu = Brain and development. 1992 Sep; 24(5):494-6. doi: NULL. [PMID: 1389335]
  • R Doi, K Inoue, K Hara, T Tobe. Levels of cefmenoxime in sera and peritoneal tissues of patients undergoing gastrointestinal surgery. Antimicrobial agents and chemotherapy. 1992 Jul; 36(7):1483-6. doi: 10.1128/aac.36.7.1483. [PMID: 1510444]
  • J J Schentag, D E Nix, M H Adelman. Mathematical examination of dual individualization principles (I): Relationships between AUC above MIC and area under the inhibitory curve for cefmenoxime, ciprofloxacin, and tobramycin. DICP : the annals of pharmacotherapy. 1991 Oct; 25(10):1050-7. doi: 10.1177/106002809102501003. [PMID: 1803788]
  • D L Onks, J F Harris, A F Robertson. Cefmenoxime and bilirubin: competition for albumin binding. Pharmacology & toxicology. 1991 May; 68(5):329-31. doi: 10.1111/j.1600-0773.1991.tb01248.x. [PMID: 1946178]
  • G Duncker, A Beigel, F Schmidt, U Ullmann, Y Walpuski. [Cefmenoxime penetration in human lacrimal sac mucosa after systemic administration]. Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft. 1991; 88(6):861-4. doi: NULL. [PMID: 1794822]
  • N Katoh, T Sugiyama, Y Ono, S Hirabayashi. [Diffusion of cefmenoxime into prostatic fluid in the patients with acute bacterial prostatitis]. Hinyokika kiyo. Acta urologica Japonica. 1990 Nov; 36(11):1287-93. doi: NULL. [PMID: 2288308]
  • J Shimada, A Saito, K Shiba, M Kaji, S Hori, M Yoshida, T Miyahara. [Effects of antacids on absorption, excretion and metabolism of cefteram pivoxil]. The Japanese journal of antibiotics. 1990 Aug; 43(8):1353-70. doi: NULL. [PMID: 2178195]
  • T Hishikawa, T Kusunoki, K Tsuchiya, Y Uzuka, T Sakamoto, T Nagatake, K Matsumoto. Application of mathematical model to experimental chemotherapy of fatal murine pneumonia. Antimicrobial agents and chemotherapy. 1990 Feb; 34(2):326-31. doi: 10.1128/aac.34.2.326. [PMID: 2183718]
  • J J Schentag. Correlation of pharmacokinetic parameters to efficacy of antibiotics: relationships between serum concentrations, MIC values, and bacterial eradication in patients with gram-negative pneumonia. Scandinavian journal of infectious diseases. Supplementum. 1990; 74(?):218-34. doi: NULL. [PMID: 2097710]
  • Y Ikeda, Y Fukuoka, K Motomura, T Yasuda, T Nishino. Paradoxical activity of beta-lactam antibiotics against Proteus vulgaris in experimental infection in mice. Antimicrobial agents and chemotherapy. 1990 Jan; 34(1):94-7. doi: 10.1128/aac.34.1.94. [PMID: 2183712]
  • C M Hicks, M L Powell. Rapid analysis of ceftetrame in human plasma using sorbent extraction and high-performance liquid chromatography. Journal of chromatography. 1989 Dec; 497(?):349-54. doi: 10.1016/0378-4347(89)80041-6. [PMID: 2625473]
  • T Motohiro, A Kawakami, K Tanaka, T Koga, Y Shimada, S Tomita, Y Sakata, T Fujimoto, T Nishiyama, N Kuda. [Pharmacokinetic and clinical studies on cefmenoxime in neonates and premature infants]. The Japanese journal of antibiotics. 1989 Dec; 42(12):2672-91. doi: NULL. [PMID: 2614921]
  • Y Toyonaga, M Sugita, Y Kurosu, M Hori, K Seo. [Pharmacokinetic and clinical studies of cefmenoxime in neonates and premature infants]. The Japanese journal of antibiotics. 1989 Dec; 42(12):2593-606. doi: NULL. [PMID: 2614916]
  • N Iwai, M Shibata, F Mizoguchi, H Nakamura, M Katayama, Y Taneda, K Inokuma, T Ozaki, T Ichikawa, S Matsui. [Pharmacokinetic and clinical studies on cefmenoxime in neonates and infants]. The Japanese journal of antibiotics. 1989 Dec; 42(12):2641-60. doi: NULL. [PMID: 2614919]
  • K Fujita, K Murono, H Sakata, H Kakehashi, T Oka, M Kaeriyama, H Yoshioka, S Maruyama, N Sanae. [Clinical and pharmacokinetic evaluation of cefmenoxime in neonates and young infants]. The Japanese journal of antibiotics. 1989 Dec; 42(12):2574-81. doi: NULL. [PMID: 2614914]
  • S Nakazawa, H Sato, Y Hirama, A Narita, K Matsumoto, S Nakazawa, H Suzuki, Y Nakanishi, H Chikaoka, K Niino. [Pharmacokinetic and clinical studies on cefmenoxime in newborn infants]. The Japanese journal of antibiotics. 1989 Dec; 42(12):2627-40. doi: NULL. [PMID: 2614918]
  • T Haruta, K Okura, H Yamamoto, S Kuroki, K Yamaoka, Y Kobayashi. [Clinical evaluation of cefmenoxime in infections of neonates]. The Japanese journal of antibiotics. 1989 Dec; 42(12):2661-71. doi: NULL. [PMID: 2614920]
  • N Cho, K Fukunaga, K Kunii. [Fundamental and clinical studies on cefmenoxime in perinatal period]. The Japanese journal of antibiotics. 1989 Dec; 42(12):2692-708. doi: NULL. [PMID: 2614922]
  • K Sunakawa, Y Ishizuka, H Akita, S Iwata, Y Sato. [Bacteriological and clinical evaluations of cefmenoxime in neonates and premature infants]. The Japanese journal of antibiotics. 1989 Dec; 42(12):2617-26. doi: NULL. [PMID: 2693755]
  • H Nakamura, N Iwai. [Pharmacokinetic studies on oral antibiotics in pediatrics. II. A pharmacokinetic study on cefteram pivoxil in pediatrics]. The Japanese journal of antibiotics. 1989 Sep; 42(9):1981-2003. doi: NULL. [PMID: 2810759]
  • H Sato, A Narita, S Nakazawa, H Suzuki, K Matsumoto, Y Nakanishi, K Niino, S Nakazawa. [Clinical studies on cefteram pivoxil granules in pediatrics]. The Japanese journal of antibiotics. 1989 Sep; 42(9):1948-62. doi: NULL. [PMID: 2810757]
  • M Minamitani, K Hachimori, K Kaneda. [A clinical study on cefteram pivoxil in the field of pediatrics]. The Japanese journal of antibiotics. 1989 Sep; 42(9):1938-47. doi: NULL. [PMID: 2810756]
  • T Nishimura, K Tabuki, T Takashima, S Aoki, M Takagi. [Laboratory and clinical studies of cefteram pivoxil in pediatric field]. The Japanese journal of antibiotics. 1989 Sep; 42(9):2004-15. doi: NULL. [PMID: 2810760]
  • T Motohiro, Y Yoshinaga, K Oda, M Aramaki, A Kawakami, K Tanaka, T Koga, S Tomita, Y Sakata, F Yamashita. [Pharmacokinetic and clinical studies of cefteram pivoxil granule in the pediatric field]. The Japanese journal of antibiotics. 1989 Sep; 42(9):2023-61. doi: NULL. [PMID: 2810762]
  • Y Toyonaga, H Imai, M Sugita, Y Fukushima, M Yamazaki, M Hori. [Bacteriological, pharmacokinetic and clinical studies on cefteram pivoxil in the pediatric field]. The Japanese journal of antibiotics. 1989 Aug; 42(8):1799-814. doi: . [PMID: 2810743]
  • F Hayakawa, K Kuno, A Ogawa, Y Nakao, H Takeuchi, Y Ando, O Kito. [Laboratory and clinical studies on cefteram pivoxil in the field of pediatrics]. The Japanese journal of antibiotics. 1989 Aug; 42(8):1849-59. doi: . [PMID: 2810748]
  • Y Wagatsuma, A Takase, N Fukushima, A Ishikawa, S Takahashi. [Clinical evaluation of cefteram pivoxil fine granules in pediatric infections]. The Japanese journal of antibiotics. 1989 Aug; 42(8):1735-44. doi: NULL. [PMID: 2810737]
  • G Suzuki, A Watanabe. [Laboratory and clinical studies on cefteram pivoxil in pediatric field]. The Japanese journal of antibiotics. 1989 Aug; 42(8):1751-60. doi: NULL. [PMID: 2810739]
  • H Sakata, H Kakehashi, K Fujita, H Yoshioka, K Iseki, K Murono, Y Takahashi. [Clinical and pharmacokinetic evaluation of cefteram pivoxil in children]. The Japanese journal of antibiotics. 1989 Aug; 42(8):1727-34. doi: NULL. [PMID: 2810736]
  • S Iwata, K Yamada, Y Kin, T Yokota, Y Kusumoto, Y Sato, H Akita, S Nanri, T Oikawa, K Sunakawa. [The influence of cefteram pivoxil on the intestinal bacterial flora]. The Japanese journal of antibiotics. 1989 Aug; 42(8):1761-79. doi: NULL. [PMID: 2810740]
  • T Shinozaki, C Nonaka, K Togasaki. [Clinical studies on cefteram pivoxil in the field of pediatrics]. The Japanese journal of antibiotics. 1989 Aug; 42(8):1837-44. doi: NULL. [PMID: 2810746]
  • D M Poisson, P Martin, C Bidault, C Gueveler. [Modification of aerobic digestive flora in patients in intensive care during and after treatment with cefmenoxime]. Pathologie-biologie. 1989 May; 37(5):350-2. doi: NULL. [PMID: 2674867]
  • V Joly, B Pangon, N Brion, J M Vallois, C Carbon. Enhancement of the therapeutic effect of cephalosporins in experimental endocarditis by altering their pharmacokinetics with diclofenac. The Journal of pharmacology and experimental therapeutics. 1988 Aug; 246(2):695-700. doi: NULL. [PMID: 3042958]
  • M D Blanchin, M L Rondot-Dudragne, H Fabre, B Mandrou. Determination of cefotaxime, desacetylcefotaxime, cefmenoxime and ceftizoxime in biological samples by fluorescence detection after separation by thin-layer chromatography. The Analyst. 1988 Jun; 113(6):899-902. doi: 10.1039/an9881300899. [PMID: 3218764]
  • H Hasegawa, N Itagaki, M Tsujino, K Takahashi, Y Yamamoto, A Imada, A Horiuchi. [Pharmacokinetics of cefmenoxime in renal-failure patients undergoing continuous arteriovenous hemofiltration]. The Japanese journal of antibiotics. 1988 Mar; 41(3):338-41. doi: NULL. [PMID: 3165473]
  • K Hirai, T Kobayashi, H Kobayashi, T Shibamoto, K Kubo, K Kitazawa, H Yagi, S Kusama. [Tissue distribution of beta-lactam antibiotics, cefotiam and cefmenoxime in the lungs of sheep]. The Japanese journal of antibiotics. 1988 Jan; 41(1):48-52. doi: NULL. [PMID: 3163382]
  • N Oldfield, D Chang, W Garland, C Town. Quantitation of ceftetrame in human plasma and urine by high-performance liquid chromatography. Journal of chromatography. 1987 Nov; 422(?):135-43. doi: 10.1016/0378-4347(87)80446-2. [PMID: 3437002]
  • T Sakata, T Kawara, H Kashikie, Y Nishi, M Kobayashi, M Kumate, E Yamamoto. [Pharmacokinetics of cefmenoxime in serum and myocardial tissue]. Kyobu geka. The Japanese journal of thoracic surgery. 1987 Nov; 40(12):984-7. doi: NULL. [PMID: 3481418]
  • M Imaizumi, T Niimi, M Kajita, T Uchida, I Kamiya, T Takahashi, Y Uchida, M Asaoka, T Abe. [Clinical study of cefmenoxime in thoracic surgery. Transfer of cefmenoxime to lung tissue and pleural fluid and prophylaxis of postoperative infections]. The Japanese journal of antibiotics. 1987 Sep; 40(9):1628-38. doi: NULL. [PMID: 3480362]
  • H Aoyama, Y Izawa, A Nishizaki, J Okuda. Optimal conditions for injection of tobramycin and cefmenoxime into burn patients. Burns, including thermal injury. 1987 Aug; 13(4):269-76. doi: 10.1016/0305-4179(87)90044-1. [PMID: 3478113]
  • N M Le Saux, L A Slaney, F A Plummer, A R Ronald, R C Brunham. In vitro activity of ceftriaxone, cefetamet (Ro 15-8074), ceftetrame (Ro 19-5247; T-2588), and fleroxacin (Ro 23-6240; AM-833) versus Neisseria gonorrhoeae and Haemophilus ducreyi. Antimicrobial agents and chemotherapy. 1987 Jul; 31(7):1153-4. doi: 10.1128/aac.31.7.1153. [PMID: 2959199]
  • B Pangon, V Joly, J M Vallois, L Abel, A Buré, N Brion, A Contrepois, C Carbon. Comparative efficacy of cefotiam, cefmenoxime, and ceftriaxone in experimental endocarditis and correlation with pharmacokinetics and in vitro efficacy. Antimicrobial agents and chemotherapy. 1987 Apr; 31(4):518-22. doi: 10.1128/aac.31.4.518. [PMID: 3300530]
  • Y Matsuura, H Yamashina, M Higo, T Fujii, M Yamamoto, H Shimamoto. [Prophylactic effects of cefmenoxime against postoperative infections after thoracotomy. Studies of cefmenoxime transfer from serum to pleural fluid and of clinical effects of cefmenoxime]. The Japanese journal of antibiotics. 1987 Feb; 40(2):295-302. doi: NULL. [PMID: 3474428]
  • P Veyssier, A Bryskier, J Modai, A Boquet, J B Fourtillan. [Pharmacokinetics of cefmenoxime in the aged subject (60 to 90 years of age) after an intravenous injection of 1 g]. Pathologie-biologie. 1986 Dec; 34(10):1081-3. doi: NULL. [PMID: 3547264]
  • K Konishi. Pharmacokinetics of cefmenoxime in patients with impaired renal function and in those undergoing hemodialysis. Antimicrobial agents and chemotherapy. 1986 Dec; 30(6):901-5. doi: 10.1128/aac.30.6.901. [PMID: 3468882]
  • S Tsuda, K Nishida, T Maekawa, T Abe, T Takino, H Fujii, M Taniwaki, H Yashige, S Horiike, S Yokota. [Clinical evaluation of cefmenoxime in severe infections in leukemia and related disorders]. The Japanese journal of antibiotics. 1986 Oct; 39(10):2651-60. doi: NULL. [PMID: 3468272]
  • J Shimada, A Saito, K Shiba, T Yamaji, T Hojo, M Kaji, S Hori, S Okuda, T Miyahara. [Pharmacokinetic studies of a new oral cephem T-2588. Pharmacokinetics in gastrectomized volunteers and the renal excretory system in healthy volunteers]. The Japanese journal of antibiotics. 1986 Oct; 39(10):2701-9. doi: NULL. [PMID: 3806955]
  • H Tsuburaya, Y Ando, I Kimizima, I Watanabe, R Abe, T Funayama, Y Kawaguchi. [A study on the penetration of cefmenoxime into bile and gallbladder tissues and the pathological changes of inflamed tissues]. The Japanese journal of antibiotics. 1986 Sep; 39(9):2381-5. doi: NULL. [PMID: 3467080]
  • K Shindo, T Tsuburaya, Y Atsumi, M Sato. [Pharmacokinetic studies on cefmenoxime. Distribution into the uterus and intrapelvic genital organs]. The Japanese journal of antibiotics. 1986 Sep; 39(9):2386-93. doi: NULL. [PMID: 3467081]
  • H Nakada, Y Kawamura, T Shibata, Y Nojima, T Sanzen, K Yoshida, T Yoneda. [A subacute oral toxicity study of T-2588 in juvenile rats]. The Japanese journal of antibiotics. 1986 Sep; 39(9):2285-300. doi: NULL. [PMID: 3795478]
  • Y Shoda, S Matsuyama, A Takarada, M Arai, K Nagashima, G Nakano, T Nakamura, K Kamisaka, T Matsuzawa, T Yoshino. [Concentrations of cefmenoxime and cefotiam in the bile and gallbladder tissue following intravenous administration in patients with biliary tract diseases]. The Japanese journal of antibiotics. 1986 May; 39(5):1259-72. doi: NULL. [PMID: 3463776]
  • I Saikawa, T Maeda, Y Nakashima, H Sakai, H Hayakawa, M Onoda, H Matsutani. [Studies on absorption, distribution and excretion of 14C labeled pivaloyloxymethyl (+)-(6R,7R)- 7-[(Z)-2-(2-amino-4-thiazolyl)-2-methoxyiminoacetamido]- 3-[(5-methyl-2H-tetrazol-2-yl)methyl]-8-oxo-5-thia- 1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate (14C-T-2588) in rats and mice]. The Japanese journal of antibiotics. 1986 Apr; 39(4):979-90. doi: NULL. [PMID: 3761551]
  • S Hirai, T Kodama, T Hiraiwa, N Abe, H Arai, S Ono, M Omori, Y Nakada, K Hashiba, K Tanada. [General pharmacology of T-2588, a new oral cephem antibiotic]. The Japanese journal of antibiotics. 1986 Apr; 39(4):958-78. doi: NULL. [PMID: 3761550]
  • H Shiozaki, S Aeba, H Matsumoto, R Usui, S Totsuka, T Kusaba, T Mishima, S Hasegawa, K Iijima, A Okano. [Clinical studies on the transference of cephem-type antibiotics into bile and gallbladder tissues with special reference to cefotiam and cefmenoxime]. The Japanese journal of antibiotics. 1986 Mar; 39(3):751-60. doi: NULL. [PMID: 3461175]
  • K Fujita, M Yokoyama. [Clinical study on the tissue distribution of cefmenoxime in the field of otolaryngology]. The Japanese journal of antibiotics. 1986 Mar; 39(3):721-5. doi: NULL. [PMID: 3461174]
  • Y Kita, K Itakura, K Tsuchiya, A Imada. Pharmacokinetics of SCE-1141, a stereoisomer of cefmenoxime, in rats. The Journal of antimicrobial chemotherapy. 1986 Feb; 17(2):205-13. doi: 10.1093/jac/17.2.205. [PMID: 3457784]
  • C Serieys, E Bergogne-Berezin, H Kafe, A Bryskier. Study of the diffusion of cefmenoxime into the bronchial secretions. Chemotherapy. 1986; 32(1):1-6. doi: 10.1159/000238382. [PMID: 3456295]
  • D A Sica, R E Polk, T M Kerkering, P Patterson, J Baggett. Cefmenoxime kinetics during continuous ambulatory peritoneal dialysis. European journal of clinical pharmacology. 1986; 30(6):713-7. doi: 10.1007/bf00608221. [PMID: 3464435]
  • Y Teranishi, T Tazaki, T Abe, M Honda, A Ohishi, Y Endoh, O Konno, A Usuba, H Inoue, M Shoji. [Transfer of cefmenoxime to lung tissue and thoracic muscle in thoracic surgery]. The Japanese journal of antibiotics. 1986 Jan; 39(1):127-32. doi: NULL. [PMID: 3457962]
  • M Nomura, K Tanaka, M Kiyomihara, N Tani, H Hasan, H Okui, T Ishikawa, T Shimosato. [Investigation of the concentration of cefmenoxime transferred to human serum and tissues in oral region]. The Japanese journal of antibiotics. 1985 Nov; 38(11):3111-7. doi: NULL. [PMID: 3867761]
  • G F Tansino, M R Hammerschlag, B L Congeni, P A Cox, B Doraiswamy, L duBouchet. Clinical efficacy and safety of cefmenoxime in children. Antimicrobial agents and chemotherapy. 1985 Oct; 28(4):508-10. doi: 10.1128/aac.28.4.508. [PMID: 3865630]
  • B Rao, E W Savage, S K Chuah, M B Bansal, V K Dhawan, H Thadepalli. Cefmenoxime therapy for gynecologic and obstetric infections. Obstetrics and gynecology. 1985 Sep; 66(3):377-83. doi: NULL. [PMID: 3860790]
  • Y Matsumoto, S Ninomaru, T Koshobu, J Ishikawa, S Nakatani, T Sasaki. [Serum levels and sputum levels of cefmenoxime in respiratory tract infections]. The Japanese journal of antibiotics. 1985 Jun; 38(6):1638-42. doi: NULL. [PMID: 3862881]
  • A Takai. [Immunological studies on the antigenicity of the cephem antibiotic T-2588]. The Japanese journal of antibiotics. 1985 Jun; 38(6):1693-702. doi: NULL. [PMID: 3840213]
  • S Ishiyama, S Katagiri, N Seo, S Yagi, H Iizawa, T Hoshikawa, T Hara, J Kameyama, M Tsukamoto, C Takahashi. [The concentration of cefmenoxime after intravenous drip infusion in digestive organs and exudates from abdominal and thoracic cavities in human]. The Japanese journal of antibiotics. 1985 Jun; 38(6):1643-7. doi: NULL. [PMID: 3862882]
  • H Washida, M Tsugaya, N Hirao, H Sakagami, Y Iwase. [Pharmacokinetic study of cefmenoxime concerning its transfer into tissues]. The Japanese journal of antibiotics. 1985 Jun; 38(6):1648-53. doi: NULL. [PMID: 3862883]
  • J Guibert, J F Acar, D Destree, A Bryskier. [Clinical evaluation of cefmenoxime in urinary tract and prostatic infections]. Pathologie-biologie. 1985 May; 33(5):330-4. doi: NULL. [PMID: 3897962]
  • K Kataoka, S Kaneko, T Kurita. [Study on the prostatic tissue levels of cefmenoxime (CMX)]. Hinyokika kiyo. Acta urologica Japonica. 1985 Feb; 31(2):273-9. doi: NULL. [PMID: 2409786]
  • S Tsuchida, S Sasaki, H Takada, S Miyagata, S Sato, S Shimizu, F Sakamoto, N Kizu. [Clinical evaluation of cefmenoxime (CMX) for complicated urinary tract infection]. Hinyokika kiyo. Acta urologica Japonica. 1985 Feb; 31(2):365-74. doi: NULL. [PMID: 3859998]
  • N Nagae, M Kobayashi, M Washio. [Transference of cefmenoxime from serum to lung tissue]. The Japanese journal of antibiotics. 1985 Jan; 38(1):41-4. doi: NULL. [PMID: 3857361]
  • Y Shibata, H Nogaki, K Ishida, T Kawaguchi. [A study on transference of cefmenoxime into the cerebrospinal fluid]. The Japanese journal of antibiotics. 1985 Jan; 38(1):45-8. doi: NULL. [PMID: 3857362]
  • A Ashiki, Y Sudo, T Suzuki, K Yamato, A Tsukui, W Hamada, Y Kusumi. [Clinical evaluation of cefmenoxime in chronic complicated urinary tract infection]. The Japanese journal of antibiotics. 1985 Jan; 38(1):49-61. doi: NULL. [PMID: 3857363]
  • E Bergogne-Bérézin, A Bryskier, G Berthelot, J H Ravina, D Vernant. Placental transfer of cefmenoxime in late pregnancy. Chemotherapy. 1985; 31(1):1-5. doi: 10.1159/000238306. [PMID: 3855746]
  • J B Fourtillan, A Bryskier, A Mignot, F Borsa, G Humbert. Pharmacokinetic study of cefmenoxime (SCE 1365-CMX) in healthy adults. The American journal of medicine. 1984 Dec; 77(6A):28-31. doi: 10.1016/s0002-9343(84)80071-6. [PMID: 6097120]
  • F D Daschner, E E Petersen, U Frank, D Hornig. Penetration of cefmenoxime into serum, gynecologic tissues, and heart valves. The American journal of medicine. 1984 Dec; 77(6A):4-6. doi: NULL. [PMID: 6097123]
  • E R Weissenbacher, D Adams, K Gutschow, C Peters-Welte, H G Luehr. Clinical results and concentrations of cefmenoxime in serum, amniotic fluid, mother's milk, and umbilical cord. The American journal of medicine. 1984 Dec; 77(6A):11-2. doi: 10.1016/s0002-9343(84)80066-2. [PMID: 6097116]
  • T G Sheftel, G Cierny, J L Lefrock, J T Mader. Cefmenoxime therapy in bacterial osteomyelitis. The American journal of medicine. 1984 Dec; 77(6A):17-20. doi: 10.1016/s0002-9343(84)80068-6. [PMID: 6097118]
  • J J Schentag, D P Reitberg, T J Cumbo. Cefmenoxime efficacy, safety, and pharmacokinetics in critical care patients with nosocomial pneumonia. The American journal of medicine. 1984 Dec; 77(6A):34-42. doi: 10.1016/s0002-9343(84)80073-x. [PMID: 6097122]
  • W Robens. Concentrations of cefmenoxime in human tissues. The American journal of medicine. 1984 Dec; 77(6A):32-3. doi: 10.1016/s0002-9343(84)80072-8. [PMID: 6097121]
  • J J Schentag, I L Smith, D J Swanson, C DeAngelis, J E Fracasso, A Vari, J W Vance. Role for dual individualization with cefmenoxime. The American journal of medicine. 1984 Dec; 77(6A):43-50. doi: 10.1016/s0002-9343(84)80074-1. [PMID: 6097124]
  • R R Wittke, D Adam. Cefmenoxime in surgical infections: treatment and penetration into peritoneal fluid and wound secretions. The American journal of medicine. 1984 Dec; 77(6A):7-10. doi: 10.1016/s0002-9343(84)80065-0. [PMID: 6097127]
  • R L Baker, R L Perkins. Cefmenoxime: clinical evaluation. The American journal of medicine. 1984 Dec; 77(6A):53-9. doi: 10.1016/s0002-9343(84)80076-5. [PMID: 6097126]
  • J S Tan, T M File. Cefmenoxime versus cefoxitin in the treatment of serious bacterial infections. The American journal of medicine. 1984 Dec; 77(6A):51-2. doi: 10.1016/s0002-9343(84)80075-3. [PMID: 6097125]
  • J G Gambertoglio, D P Alexander, S L Barriere. Cefmenoxime pharmacokinetics in healthy volunteers and subjects with renal insufficiency and on hemodialysis. Antimicrobial agents and chemotherapy. 1984 Dec; 26(6):845-9. doi: 10.1128/aac.26.6.845. [PMID: 6098220]
  • J M Machinist, B A Bopp, D Quinn. Metabolism of [14C]Cefmenoxime in normal subjects after intramuscular administration. Antimicrobial agents and chemotherapy. 1984 Oct; 26(4):431-5. doi: 10.1128/aac.26.4.431. [PMID: 6097162]
  • N Miyazaki, A Kajiki, H Yamazaki, S Harada, M Kido, A Kuroiwa. [Penetration of cefmenoxime into pleural fluid]. The Japanese journal of antibiotics. 1984 Oct; 37(10):1763-5. doi: NULL. [PMID: 6094856]
  • R E Polk, D A Sica, T M Kerkering, B J Kline, P M Patterson, J W Baggett. Cefmenoxime pharmacokinetics in patients with renal insufficiency. Antimicrobial agents and chemotherapy. 1984 Sep; 26(3):322-7. doi: 10.1128/aac.26.3.322. [PMID: 6095752]