Bendazac (BioDeep_00000858607)
代谢物信息卡片
化学式: C16H14N2O3 (282.10043740000003)
中文名称: 苄达酸
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC=C(C=C1)CN2C3=CC=CC=C3C(=N2)OCC(=O)O
InChI: InChI=1S/C16H14N2O3/c19-15(20)11-21-16-13-8-4-5-9-14(13)18(17-16)10-12-6-2-1-3-7-12/h1-9H,10-11H2,(H,19,20)
描述信息
M - Musculo-skeletal system > M02 - Topical products for joint and muscular pain > M02A - Topical products for joint and muscular pain > M02AA - Antiinflammatory preparations, non-steroids for topical use
S - Sensory organs > S01 - Ophthalmologicals > S01B - Antiinflammatory agents > S01BC - Antiinflammatory agents, non-steroids
C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic
D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents
D002491 - Central Nervous System Agents > D000700 - Analgesics
D000893 - Anti-Inflammatory Agents
D018501 - Antirheumatic Agents
同义名列表
1 个代谢物同义名
数据库引用编号
6 个数据库交叉引用编号
- ChEBI: CHEBI:31257
- KEGGdrug: D01594
- PubChem: 2313
- DrugBank: DB13501
- ChEMBL: CHEMBL1089221
- CAS: 20187-55-7
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Munish Ahuja, Avinash S Dhake, Surendra K Sharma, Dipak K Majumdar. Topical ocular delivery of NSAIDs.
The AAPS journal.
2008 Jun; 10(2):229-41. doi:
10.1208/s12248-008-9024-9. [PMID: 18437583] - L Saso, B Silvestrini. Antidenaturant drugs for cataract and other condensation diseases.
Medical hypotheses.
2001 Jan; 56(1):114-20. doi:
10.1054/mehy.2000.1128. [PMID: 11133267] - L Saso, G Valentini, M L Casini, E Mattei, L Braghiroli, G Mazzanti, C Panzironi, E Grippa, B Silvestrini. Inhibition of protein denaturation by fatty acids, bile salts and other natural substances: a new hypothesis for the mechanism of action of fish oil in rheumatic diseases.
Japanese journal of pharmacology.
1999 Jan; 79(1):89-99. doi:
10.1254/jjp.79.89. [PMID: 10082322] - L Saso, G Valentini, E Grippa, M G Leone, B Silvestrini. Effect of selected substances on heat-induced aggregation of albumin, IgG and lysozyme.
Research communications in molecular pathology and pharmacology.
1998 Oct; 102(1):15-28. doi:
. [PMID: 9920343] - J M Prieto de Paula, E Rodríguez Rodríguez, V Villamandos Nicás, H Sanz de la Fuente, A Prada Mínguez, A del Portillo Rubí. [Bendazac hepatotoxicity: analysis of 16 cases].
Revista clinica espanola.
1995 Jun; 195(6):387-9. doi:
NULL. [PMID: 7644786] - B Catanese, M Panei, R Picollo, B Martinelli, M G Ciarniello, S Baravelli. Validation of a HPLC method for the determination of bendazac and its main metabolite 5-hydroxybendazac in human plasma.
Bollettino chimico farmaceutico.
1992 Jan; 131(1):22-9. doi:
NULL. [PMID: 1622607] - M J Crabbe, S T Hoe. Aldehyde dehydrogenase, aldose reductase, and free radical scavengers in cataract.
Enzyme.
1991; 45(4):188-93. doi:
10.1159/000468888. [PMID: 1823864] - M R Bruno, M Sensi, G P Cioccia, L Valente, M Negri, G Ghirlanda, P Pozzilli. Inhibition of protein non-enzymic glycation induced by Bendazac.
Diabetes research (Edinburgh, Scotland).
1988 Sep; 9(1):11-4. doi:
NULL. [PMID: 3240633] - V Rovei, J Escourrou, G Campistron, D Ego, A Thiola, A Ribet, G Houin. The pharmacokinetics of bendazac-lysine and 5-hydroxybendazac, its main metabolite, in patients with hepatic cirrhosis.
European journal of clinical pharmacology.
1988; 35(4):391-6. doi:
10.1007/bf00561370. [PMID: 3197747] - K Staley, R Coxon, G Gallacher, J Landon. Development of separation fluoroimmunoassays for bendazac and 5-hydroxy bendazac.
Therapeutic drug monitoring.
1988; 10(3):321-6. doi:
10.1097/00007691-198803000-00015. [PMID: 3176111] - G Musci, B Silvestrini. Mechanism of the scavenger-like activity of bendazac.
Drugs under experimental and clinical research.
1987; 13(5):289-92. doi:
NULL. [PMID: 3678037] - P Valeri, M Palmery, B Tita, B Silvestrini. Investigations on the ocular pharmacokinetics of bendazac in rabbits.
Experimental and molecular pathology.
1985 Dec; 43(3):283-7. doi:
10.1016/0014-4800(85)90065-6. [PMID: 4065307] - J E De Larco, D A Pigott. Ectopic peptides released by a human melanoma cell line that modulate the transformed phenotype.
Ciba Foundation symposium.
1985; 116(?):224-40. doi:
10.1002/9780470720974.ch14. [PMID: 3000706] - B Catanese, A Rossi, B Silvestrini, G Toschi. Effect of bendazac and phenylbutazone on polymerization of bovine serum albumin.
Pharmacological research communications.
1976 Dec; 8(6):549-55. doi:
10.1016/0031-6989(76)90046-1. [PMID: 1026974]