Pitavastatin calcium (BioDeep_00000858556)
代谢物信息卡片
Pitavastatin calcium
化学式: C50H46CaF2N2O8 (880.284797)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1CC1C2=NC3=CC=CC=C3C(=C2C=CC(CC(CC(=O)[O-])O)O)C4=CC=C(C=C4)F.C1CC1C2=NC3=CC=CC=C3C(=C2C=CC(CC(CC(=O)[O-])O)O)C4=CC=C(C=C4)F.[Ca+2]
InChI: /q
描述信息
D057847 - Lipid Regulating Agents > D000960 - Hypolipidemic Agents > D000924 - Anticholesteremic Agents
D004791 - Enzyme Inhibitors > D019161 - Hydroxymethylglutaryl-CoA Reductase Inhibitors
C78276 - Agent Affecting Digestive System or Metabolism > C29703 - Antilipidemic Agent
C471 - Enzyme Inhibitor > C1655 - HMG-CoA Reductase Inhibitor
D009676 - Noxae > D000963 - Antimetabolites
同义名列表
1 个代谢物同义名
数据库引用编号
5 个数据库交叉引用编号
- ChEBI: CHEBI:71258
- ChEBI: CHEBI:94569
- KEGGdrug: D01862
- PubChem: 5282451
- ChEMBL: CHEMBL1237061
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Michael T Lu, Heather Ribaudo, Borek Foldyna, Markella V Zanni, Thomas Mayrhofer, Julia Karady, Jana Taron, Kathleen V Fitch, Sara McCallum, Tricia H Burdo, Kayla Paradis, Sandeep S Hedgire, Nandini M Meyersohn, Christopher DeFilippi, Carlos D Malvestutto, Audra Sturniolo, Marissa Diggs, Sue Siminski, Gerald S Bloomfield, Beverly Alston-Smith, Patrice Desvigne-Nickens, Edgar T Overton, Judith S Currier, Judith A Aberg, Carl J Fichtenbaum, Udo Hoffmann, Pamela S Douglas, Steven K Grinspoon. Effects of Pitavastatin on Coronary Artery Disease and Inflammatory Biomarkers in HIV: Mechanistic Substudy of the REPRIEVE Randomized Clinical Trial.
JAMA cardiology.
2024 Apr; 9(4):323-334. doi:
10.1001/jamacardio.2023.5661. [PMID: 38381407] - M John Chapman, Alexina Orsoni, Natalie A Mellett, Anh Nguyen, Paul Robillard, Jonathan E Shaw, Philippe Giral, Patrice Thérond, Debi Swertfeger, W Sean Davidson, Peter J Meikle. Pitavastatin treatment remodels the HDL subclass lipidome and proteome in hypertriglyceridemia.
Journal of lipid research.
2024 02; 65(2):100494. doi:
10.1016/j.jlr.2023.100494. [PMID: 38160756] - Kiwamu Kamiya, Makoto Takei, Toshiyuki Nagai, Toru Miyoshi, Hiroshi Ito, Yoshihiro Fukumoto, Hitoshi Obara, Tatsuyuki Kakuma, Ichiro Sakuma, Hiroyuki Daida, Satoshi Iimuro, Hiroaki Shimokawa, Takeshi Kimura, Ryozo Nagai, Toshihisa Anzai. Association between Non-Lipid Residual Risk Factors and Cardiovascular Events in Patients with Stable Coronary Artery Disease Treated with Pitavastatin: An Observation from the REAL-CAD Study.
Journal of atherosclerosis and thrombosis.
2024 Jan; 31(1):61-80. doi:
10.5551/jat.64304. [PMID: 37574272] - Hina Arsh, Asif Ali, Raja Ram Khenhrani, Fnu Simran, Umbish Dino, Sweta Tamang, Fnu Manoj, Shuaita Bai, Monika Bai, Gianeshwareealias Rachna Panjwani, Deepak Kumar, Deepa Rani, Fnu Partab, Jahanzeb Malik. Efficacy and Safety of Pitavastatin in Patients with Impaired Glucose Tolerance: An Updated Review.
Current problems in cardiology.
2023 Jul; 48(11):101981. doi:
10.1016/j.cpcardiol.2023.101981. [PMID: 37473935] - Jiaying Wang, Jinliang Chen, Lu Wang, Dandan Yang, Rong Shao, Honggang Lou, Zourong Ruan, Bo Jiang. Evaluating the bioequivalence of two pitavastatin calcium formulations based on IVIVC modeling and clinical study.
Clinical and translational science.
2023 01; 16(1):85-91. doi:
10.1111/cts.13426. [PMID: 36178248] - Ming-Ting Chou, Anthony McGirr, Gwo-Ping Jong, Ting-Hsing Chao, I-Te Lee, Chun-Yao Huang, Ching-Pei Chen, Chang-Hsun Hsieh, Chieh-Hsiang Lu, Wayne Huey-Herng Sheu. Effect of 1PC111, a Fixed-dose Combination of Pitavastatin and Ezetimibe, Versus Pitavastatin or Ezetimibe Monotherapy on Lipid Profiles in Patients With Hypercholesterolemia or Mixed Dyslipidemia: A Randomized, Double-blind, Multicenter, Phase III Study.
Clinical therapeutics.
2022 10; 44(10):1272-1281. doi:
10.1016/j.clinthera.2022.08.006. [PMID: 36030106] - Paul Grocki, Mark Woollam, Luqi Wang, Shengzhi Liu, Maitri Kalra, Amanda P Siegel, Bai-Yan Li, Hiroki Yokota, Mangilal Agarwal. Chemometric Analysis of Urinary Volatile Organic Compounds to Monitor the Efficacy of Pitavastatin Treatments on Mammary Tumor Progression over Time.
Molecules (Basel, Switzerland).
2022 Jul; 27(13):. doi:
10.3390/molecules27134277. [PMID: 35807522] - Joo Young Na, Eunsol Yang, Jae-Hoon Kim, In Sun Kwon, Eun-Heui Jin, Kyung-Sang Yu, Jinsook Kim, SeungHwan Lee, Jang Hee Hong. Comparative Pharmacokinetics Between a Fixed-Dose Combination of Pitavastatin/Valsartan 4/160 mg and the Corresponding Individual Components Through a Partial Replicated Crossover Design in Healthy Male Subjects.
Clinical pharmacology in drug development.
2022 05; 11(5):615-622. doi:
10.1002/cpdd.1054. [PMID: 34997835] - Takuya Matsumoto, Shinichiro Yoshino, Tadashi Furuyama, Koichi Morisaki, Kaku Nakano, Jun-Ichiro Koga, Yoshihiko Maehara, Kimihiro Komori, Masaki Mori, Kensuke Egashira. Pitavastatin-Incorporated Nanoparticles for Chronic Limb Threatening Ischemia: A Phase I/IIa Clinical Trial.
Journal of atherosclerosis and thrombosis.
2022 May; 29(5):731-746. doi:
10.5551/jat.58941. [PMID: 33907060] - Daiji Nagayama, Atsuhito Saiki, Yasuhiro Watanabe, Takashi Yamaguchi, Masahiro Ohira, Naoko Sato, Mizuho Kanayama, Masao Moroi, Yoh Miyashita, Kohji Shirai, Ichiro Tatsuno. Prevention of Cardiovascular Events with Pitavastatin is Associated with Increased Serum Lipoprotein Lipase Mass Level: Subgroup Analysis of the TOHO-LIP.
Journal of atherosclerosis and thrombosis.
2022 Apr; 29(4):451-463. doi:
10.5551/jat.62141. [PMID: 33642441] - Atsushi Kimura, Kenya Kamimura, Marina Ohkoshi-Yamada, Yoko Shinagawa-Kobayashi, Ryo Goto, Takashi Owaki, Chiyumi Oda, Osamu Shibata, Shinichi Morita, Norihiro Sakai, Hiroyuki Abe, Takeshi Yokoo, Akira Sakamaki, Hiroteru Kamimura, Shuji Terai. Effects of a novel selective PPARα modulator, statin, sodium-glucose cotransporter 2 inhibitor, and combinatorial therapy on the liver and vasculature of medaka nonalcoholic steatohepatitis model.
Biochemical and biophysical research communications.
2022 03; 596(?):76-82. doi:
10.1016/j.bbrc.2022.01.086. [PMID: 35121372] - Francesco Fici, Gokhan Faikoglu, Bahar Arican Tarim, Nicolas Roberto Robles, Kostas Tsioufis, Guido Grassi, Barış Gungor. Pitavastatin: Coronary Atherosclerotic Plaques Changes and Cardiovascular Prevention.
High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension.
2022 Mar; 29(2):137-144. doi:
10.1007/s40292-021-00496-0. [PMID: 35064911] - Jacqueline B McCrea, Azher Hussain, Bennett Ma, Graigory C Garrett, Raymond Evers, John E Laabs, S Aubrey Stoch, Marian Iwamoto. Assessment of Pharmacokinetic Interaction Between Gefapixant (MK-7264), a P2X3 Receptor Antagonist, and the OATP1B1 Drug Transporter Substrate Pitavastatin.
Clinical pharmacology in drug development.
2022 03; 11(3):406-412. doi:
10.1002/cpdd.1047. [PMID: 34821075] - Daisaku Masuda, Shizuya Yamashita. Serum HDL-Cholesterol Level Does Not Influence Cardiovascular Event Rate under Sufficient Lowering of LDL-Cholesterol by Pitavatatin in Patients with Stable Coronary Artery Disease.
Journal of atherosclerosis and thrombosis.
2022 Jan; 29(1):8-10. doi:
10.5551/jat.ed165. [PMID: 33762513] - Ziqiang Li, Shuang Tian, Zengguang Wu, Xueyan Xu, Lei Lei, Yanfen Li, Baohe Wang, Yuhong Huang. Pharmacokinetic herb-disease-drug interactions: Effect of ginkgo biloba extract on the pharmacokinetics of pitavastatin, a substrate of Oatp1b2, in rats with non-alcoholic fatty liver disease.
Journal of ethnopharmacology.
2021 Nov; 280(?):114469. doi:
10.1016/j.jep.2021.114469. [PMID: 34329714] - Amirhossein Sahebkar, Nasim Kiaie, Armita Mahdavi Gorabi, Massimo R Mannarino, Vanessa Bianconi, Tannaz Jamialahmadi, Matteo Pirro, Maciej Banach. A comprehensive review on the lipid and pleiotropic effects of pitavastatin.
Progress in lipid research.
2021 11; 84(?):101127. doi:
10.1016/j.plipres.2021.101127. [PMID: 34509516] - Atsuhito Saiki, Yasuhiro Watanabe, Takashi Yamaguchi, Masahiro Ohira, Daiji Nagayama, Naoko Sato, Mizuho Kanayama, Mao Takahashi, Kazuhiro Shimizu, Masao Moroi, Yoh Miyashita, Kohji Shirai, Ichiro Tatsuno. CAVI-Lowering Effect of Pitavastatin May Be Involved in the Prevention of Cardiovascular Disease: Subgroup Analysis of the TOHO-LIP.
Journal of atherosclerosis and thrombosis.
2021 Oct; 28(10):1083-1094. doi:
10.5551/jat.60343. [PMID: 33342941] - Shinya Takahashi, Shu Kasama, Takuji Toyama, Shota Suzuki, Yukie Ito, Tomoaki Nakata, Masato Kasahara, Masahiko Kurabayashi. Assessment of therapeutic effects of statin on cardiac sympathetic nerve activity after reperfusion therapy in patients with first ST-segment elevation myocardial infarction and normal low-density lipoprotein cholesterol.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology.
2021 Aug; 28(4):1449-1457. doi:
10.1007/s12350-019-01857-y. [PMID: 31440976] - Sheng Feng, Qingyan Bo, Hugh A Coleman, Jean Eric Charoin, Mingfen Zhu, Jim Xiao, Yuyan Jin. Further Evaluation of Coproporphyrins as Clinical Endogenous Markers for OATP1B.
Journal of clinical pharmacology.
2021 08; 61(8):1027-1034. doi:
10.1002/jcph.1817. [PMID: 33460165] - Christine M Bowman, Buyun Chen, Jonathan Cheong, Liling Liu, Yuan Chen, Jialin Mao. Improving the Translation of Organic Anion Transporting Polypeptide Substrates using HEK293 Cell Data in the Presence and Absence of Human Plasma via Physiologically Based Pharmacokinetic Modeling.
Drug metabolism and disposition: the biological fate of chemicals.
2021 07; 49(7):530-539. doi:
10.1124/dmd.120.000315. [PMID: 33958385] - Katherine D Lynch, Michelle L Montonye, Dan-Dan Tian, Tarana Arman, Victoria O Oyanna, Baron J Bechtold, Tyler N Graf, Nicholas H Oberlies, Mary F Paine, John D Clarke. Hepatic organic anion transporting polypeptides mediate disposition of milk thistle flavonolignans and pharmacokinetic silymarin-drug interactions.
Phytotherapy research : PTR.
2021 Jun; 35(6):3286-3297. doi:
10.1002/ptr.7049. [PMID: 33587330] - Mahmoud H Teaima, Khaled M Abdel-Haleem, Rewan Osama, Mohamed A El-Nabarawi, Osama S Elnahas. A Promising Single Oral Disintegrating Tablet for Co-Delivery of Pitavastatin Calcium and Lornoxicam Using Co-Processed Excipients: Formulation, Characterization and Pharmacokinetic Study.
Drug design, development and therapy.
2021; 15(?):4229-4242. doi:
10.2147/dddt.s332729. [PMID: 34675486] - Daiji Nagayama, Atsuhito Saiki, Kohji Shirai. The Anti-Cancer Effect of Pitavastatin May Be a Drug-Specific Effect: Subgroup Analysis of the TOHO-LIP Study.
Vascular health and risk management.
2021; 17(?):169-173. doi:
10.2147/vhrm.s306540. [PMID: 33953560] - Yasufumi Katanasaka, Sae Hirano, Yoichi Sunagawa, Yusuke Miyazaki, Hikaru Sato, Masafumi Funamoto, Kana Shimizu, Satoshi Shimizu, Nurmila Sari, Koji Hasegawa, Tatsuya Morimoto. Clinically Administered Doses of Pitavastatin and Rosuvastatin.
International heart journal.
2021; 62(6):1379-1386. doi:
10.1536/ihj.21-231. [PMID: 34853228] - Xiaomin Liang, Yeojin Park, Natalie DeForest, Jia Hao, Xiaofeng Zhao, Congrong Niu, Kelly Wang, Bill Smith, Yurong Lai. In Vitro Hepatic Uptake in Human and Monkey Hepatocytes in the Presence and Absence of Serum Protein and Its In Vitro to In Vivo Extrapolation.
Drug metabolism and disposition: the biological fate of chemicals.
2020 12; 48(12):1283-1292. doi:
10.1124/dmd.120.000163. [PMID: 33037043] - In-Kyung Jeong, Sung-Rae Kim. Efficacy and Safety of Pitavastatin in a Real-World Setting: Observational Study Evaluating SaFety in Patient Treated with Pitavastatin in Korea (PROOF Study).
Endocrinology and metabolism (Seoul, Korea).
2020 12; 35(4):882-891. doi:
10.3803/enm.2020.723. [PMID: 33261312] - Hiroyuki Arashi, Junichi Yamaguchi, Erisa Kawada-Watanabe, Hisao Otsuki, Haruki Sekiguchi, Hiroshi Ogawa, Nobuhisa Hagiwara. The Effects of Lipid-Lowering Therapy on Serum Eicosapentaenoic Acid to Arachidonic Acid Ratio: An HIJ-PROPER Sub-Analysis.
Journal of cardiovascular pharmacology and therapeutics.
2020 11; 25(6):548-555. doi:
10.1177/1074248420931621. [PMID: 32567339] - Yan Xu, Yanqing Wu. Atorvastatin associated with gamma glutamyl transpeptidase elevation in a hyperlipidemia patient: A case report and literature review.
Medicine.
2020 Oct; 99(40):e22572. doi:
10.1097/md.0000000000022572. [PMID: 33019469] - Hisao Otsuki, Hiroyuki Arashi, Junichi Yamaguchi, Erisa Kawada-Watanabe, Hiroshi Ogawa, Nobuhisa Hagiwara. Effect of Ezetimibe + Pitavastatin on Cardiovascular Outcomes in Patients with ST-Segment Elevation Myocardial Infarction (from the HIJ-PROPER Study).
The American journal of cardiology.
2020 10; 132(?):15-21. doi:
10.1016/j.amjcard.2020.06.069. [PMID: 32773226] - Sang-Hyun Ihm, Woo-Baek Chung, Jong-Min Lee, Byung-Hee Hwang, Ki-Dong Yoo, Sung-Ho Her, Woo-Hyuk Song, In-Ho Chae, Tae-Ho Park, Ju-Han Kim, Dong Woon Jeon, Byung-Ryul Cho, Seung-Ho Kang, Sang-Don Park, Jin-Bae Lee, Jeong-Taek Woo, Byung-Wan Lee, Kyung-Ah Han, Kyung-Heon Won, Hyo-Soo Kim, Jae-Myung Yu, Choon Hee Chung, Hae-Jin Kim, Ho-Chan Cho, Ki-Bae Seung. Efficacy and Tolerability of Pitavastatin Versus Pitavastatin/Fenofibrate in High-risk Korean Patients with Mixed Dyslipidemia: A Multicenter, Randomized, Double-blinded, Parallel, Therapeutic Confirmatory Clinical Trial.
Clinical therapeutics.
2020 10; 42(10):2021-2035.e3. doi:
10.1016/j.clinthera.2020.08.002. [PMID: 32891418] - Rui-Xia Xu, Yan Zhang, Yue Zhang, Ya-Ru Wu, Xiao-Lin Li, Yuan-Lin Guo, Geng Liu, Qian Dong, Jian-Jun Li. Effects of Pitavastatin on Lipoprotein Subfractions and Oxidized Low-density Lipoprotein in Patients with Atherosclerosis.
Current medical science.
2020 Oct; 40(5):879-884. doi:
10.1007/s11596-020-2263-4. [PMID: 33123903] - Hae-Young Lee, Ki-Hoon Han, Woo-Baek Chung, Sung-Ho Her, Tae-Ho Park, Seung-Woon Rha, So-Yeon Choi, Kyung-Tae Jung, Jong-Seon Park, Pum-Joon Kim, Jong-Min Lee, Myung-Ho Jeong, Eun-Seok Shin, Hyeon-Cheol Gwon, Kyoo-Rok Han, Jei-Keon Chae, Woo-Shik Kim, Dong-Ju Choi, Bum-Kee Hong, Si-Wan Choi, Namsik Chung. Safety and Efficacy of Pitavastatin in Patients With Impaired Fasting Glucose and Hyperlipidemia: A Randomized, Open-labeled, Multicentered, Phase IV Study.
Clinical therapeutics.
2020 10; 42(10):2036-2048. doi:
10.1016/j.clinthera.2020.07.013. [PMID: 32921501] - Masatoki Yoshida, Kazufumi Nakamura, Toru Miyoshi, Masashi Yoshida, Megumi Kondo, Kaoru Akazawa, Tomonari Kimura, Hiroaki Ohtsuka, Yuko Ohno, Daiji Miura, Hiroshi Ito. Combination therapy with pemafibrate (K-877) and pitavastatin improves vascular endothelial dysfunction in dahl/salt-sensitive rats fed a high-salt and high-fat diet.
Cardiovascular diabetology.
2020 09; 19(1):149. doi:
10.1186/s12933-020-01132-2. [PMID: 32979918] - Edgar T Overton, Amy Kantor, Kathleen V Fitch, Paul Muntner, Khuanchai Supparatpinyo, Mosepele Mosepele, Lerato Mohapi, Sandra Wagner Cardoso, Sandesh Patil, Marcus V G de Lacerda, Grace McComsey, Judith A Aberg, Pamela S Douglas, Steven K Grinspoon, Heather Ribaudo, Christina M Wyatt. An Evaluation of Baseline Kidney Function in the REPRIEVE Trial of Pitavastatin in Human Immunodeficiency Virus.
The Journal of infectious diseases.
2020 07; 222(Suppl 1):S41-S51. doi:
10.1093/infdis/jiaa222. [PMID: 32645164] - David C Boettiger, Anthony T Newall, Pairoj Chattranukulchai, Romanee Chaiwarith, Suwimon Khusuwan, Anchalee Avihingsanon, Andrew Phillips, Eran Bendavid, Matthew G Law, James G Kahn, Jeremy Ross, Sergio Bautista-Arredondo, Sasisopin Kiertiburanakul. Statins for atherosclerotic cardiovascular disease prevention in people living with HIV in Thailand: a cost-effectiveness analysis.
Journal of the International AIDS Society.
2020 06; 23 Suppl 1(?):e25494. doi:
10.1002/jia2.25494. [PMID: 32562359] - Naeun Lee, Nirmala Tilija Pun, Won-Jun Jang, Jung Woo Bae, Chul-Ho Jeong. Pitavastatin induces apoptosis in oral squamous cell carcinoma through activation of FOXO3a.
Journal of cellular and molecular medicine.
2020 06; 24(12):7055-7066. doi:
10.1111/jcmm.15389. [PMID: 32406610] - Takayoshi Nakaoka, Yuta Uetake, Ken-Ichi Kaneko, Takashi Niwa, Hidenori Ochiai, Satsuki Irie, Yoshie Suezaki, Natsumi Otsuka, Emi Hayashinaka, Yasuhiro Wada, Yilong Cui, Kazuya Maeda, Hiroyuki Kusuhara, Yuichi Sugiyama, Takamitsu Hosoya, Yasuyoshi Watanabe. Practical Synthesis of [18F]Pitavastatin and Evaluation of Hepatobiliary Transport Activity in Rats by Positron Emission Tomography.
Molecular pharmaceutics.
2020 06; 17(6):1884-1898. doi:
10.1021/acs.molpharmaceut.9b01284. [PMID: 32271581] - Mayui Nakazawa, Hiroyuki Arashi, Junichi Yamaguchi, Hiroshi Ogawa, Nobuhisa Hagiwara. Lower levels of high-density lipoprotein cholesterol are associated with increased cardiovascular events in patients with acute coronary syndrome.
Atherosclerosis.
2020 06; 303(?):21-28. doi:
10.1016/j.atherosclerosis.2020.05.005. [PMID: 32474302] - Yongin Cho, Hyangkyu Lee, Hyun Ki Park, Eun Yeong Choe, Hye Jin Wang, Ryeong-Hyeon Kim, Youjin Kim, Eun Seok Kang. Differential Diabetogenic Effect of Pitavastatin and Rosuvastatin, in vitro and in vivo.
Journal of atherosclerosis and thrombosis.
2020 May; 27(5):429-440. doi:
10.5551/jat.50039. [PMID: 31527323] - Erisa Kawada-Watanabe, Junichi Yamaguchi, Haruki Sekiguchi, Hiroyuki Arashi, Hiroshi Ogawa, Nobuhisa Hagiwara. Targeting high-sensitivity C-reactive protein levels in acute coronary syndrome patients undergoing contemporary lipid-lowering therapy: a sub-analysis of the HIJ-PROPER trial.
Journal of cardiology.
2020 05; 75(5):500-506. doi:
10.1016/j.jjcc.2019.09.015. [PMID: 31699568] - Hiroaki Takeda, Yoshihiro Izumi, Shohei Tamura, Tomonari Koike, Yui Koike, Masashi Shiomi, Takeshi Bamba. Lipid Profiling of Serum and Lipoprotein Fractions in Response to Pitavastatin Using an Animal Model of Familial Hypercholesterolemia.
Journal of proteome research.
2020 03; 19(3):1100-1108. doi:
10.1021/acs.jproteome.9b00602. [PMID: 31965805] - Misari Patel, Charmy Kothari. Quantitative bio-analysis of pitavastatin and candesartan in rat plasma by HPLC-UV: Assessment of pharmacokinetic drug-drug interaction.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2020 Feb; 1138(?):121962. doi:
10.1016/j.jchromb.2019.121962. [PMID: 31915110] - Junying Wang, Juan Liu, Xiangrong Song, Chunmei Fu. Simultaneous Determination of Telmisartan and Pitavastatin Calcium in Intestinal Perfusate by HPLC: Application to Intestinal Absorption Interaction Study.
Pharmaceutical nanotechnology.
2020; 8(4):313-322. doi:
10.2174/2211738508666200607181727. [PMID: 32515316] - Krishnaprasad Baby, Swastika Maity, Chetan H Mehta, Akhil Suresh, Usha Y Nayak, Yogendra Nayak. Targeting SARS-CoV-2 RNA-dependent RNA polymerase: An in silico drug repurposing for COVID-19.
F1000Research.
2020; 9(?):1166. doi:
10.12688/f1000research.26359.1. [PMID: 33204411] - Christine M Bowman, Eugene Chen, Liuxi Chen, Yi-Chen Chen, Xiaorong Liang, Matthew Wright, Yuan Chen, Jialin Mao. Changes in Organic Anion Transporting Polypeptide Uptake in HEK293 Overexpressing Cells in the Presence and Absence of Human Plasma.
Drug metabolism and disposition: the biological fate of chemicals.
2020 01; 48(1):18-24. doi:
10.1124/dmd.119.088948. [PMID: 31699807] - Luqi Wang, Yue Wang, Andy Chen, Meghana Teli, Rika Kondo, Aydin Jalali, Yao Fan, Shengzhi Liu, Xinyu Zhao, Amanda Siegel, Kazumasa Minami, Mangilal Agarwal, Bai-Yan Li, Hiroki Yokota. Pitavastatin slows tumor progression and alters urine-derived volatile organic compounds through the mevalonate pathway.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
2019 12; 33(12):13710-13721. doi:
10.1096/fj.201901388r. [PMID: 31585508] - Congrong Niu, Yujin Wang, Xiaofeng Zhao, Sam Tep, Eisuke Murakami, Raju Subramanian, Bill Smith, Yurong Lai. Organic Anion-Transporting Polypeptide Genes Are Not Induced by the Pregnane X Receptor Activator Rifampin: Studies in Hepatocytes In Vitro and in Monkeys In Vivo.
Drug metabolism and disposition: the biological fate of chemicals.
2019 12; 47(12):1433-1442. doi:
10.1124/dmd.119.088922. [PMID: 31582395] - Christina Trueck, Chih-Hsuan Hsin, Oliver Scherf-Clavel, Elke Schaeffeler, Rebekka Lenssen, Malaz Gazzaz, Marleen Gersie, Max Taubert, Maria Quasdorff, Matthias Schwab, Martina Kinzig, Fritz Sörgel, Marc S Stoffel, Uwe Fuhr. A Clinical Drug-Drug Interaction Study Assessing a Novel Drug Transporter Phenotyping Cocktail With Adefovir, Sitagliptin, Metformin, Pitavastatin, and Digoxin.
Clinical pharmacology and therapeutics.
2019 12; 106(6):1398-1407. doi:
10.1002/cpt.1564. [PMID: 31247117] - Jae H Chang, Yi-Chen Chen, Jonathan Cheong, Robert S Jones, Jodie Pang. Investigating the Impact of Albumin on the Liver Uptake of Pitavastatin and Warfarin in Nagase Analbuminemic Rats.
Drug metabolism and disposition: the biological fate of chemicals.
2019 11; 47(11):1307-1313. doi:
10.1124/dmd.119.088278. [PMID: 31492695] - Hiroyuki Kimura, Yusuke Yagi, Mutsumi Mikamo, Kazuya Maeda, Shinya Kagawa, Kenji Arimitsu, Tatsuya Higashi, Ryuichi Nishii, Masahiro Ono, Yuji Nakamoto, Kaori Togashi, Hiroyuki Kusuhara, Hideo Saji. Evaluation of transporter-mediated hepatobiliary transport of newly developed 18F-labeled pitavastatin derivative, PTV-F1, in rats by PET imaging.
Drug metabolism and pharmacokinetics.
2019 Oct; 34(5):317-324. doi:
10.1016/j.dmpk.2019.05.006. [PMID: 31331824] - Oliver Scherf-Clavel, Martina Kinzig, Marc S Stoffel, Uwe Fuhr, Fritz Sörgel. Quantification of adefovir and pitavastatin in human plasma and urine by LC-MS/MS: A useful tool for drug-drug interaction studies.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2019 Sep; 1125(?):121718. doi:
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Journal of the American Heart Association.
2019 08; 8(16):e012953. doi:
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International journal of molecular sciences.
2019 Jul; 20(14):. doi:
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Nuclear medicine and biology.
2019 Jul; 74-75(?):25-31. doi:
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The Journal of pharmacy and pharmacology.
2019 Jul; 71(7):1072-1081. doi:
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Xenobiotica; the fate of foreign compounds in biological systems.
2019 May; 49(5):602-610. doi:
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Current atherosclerosis reports.
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Drug metabolism and disposition: the biological fate of chemicals.
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ALTEX.
2019; 36(4):597-612. doi:
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Heart and vessels.
2019 Jan; 34(1):62-73. doi:
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Clinical and experimental hypertension (New York, N.Y. : 1993).
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Clinical pharmacokinetics.
2018 12; 57(12):1559-1570. doi:
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The American journal of cardiology.
2018 12; 122(11):1817-1823. doi:
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Cardiovascular drugs and therapy.
2018 12; 32(6):581-589. doi:
10.1007/s10557-018-6826-6. [PMID: 30187345] - Kaku Nakano, Tetsuya Matoba, Jun-Ichiro Koga, Yushi Kashihara, Masato Fukae, Ichiro Ieiri, Masanari Shiramoto, Shin Irie, Junji Kishimoto, Koji Todaka, Kensuke Egashira. Safety, Tolerability, and Pharmacokinetics of NK-104-NP.
International heart journal.
2018 Sep; 59(5):1015-1025. doi:
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American journal of hypertension.
2018 09; 31(10):1139-1146. doi:
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Drug metabolism and disposition: the biological fate of chemicals.
2018 07; 46(7):953-963. doi:
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Journal of pharmaceutical sciences.
2018 07; 107(7):1791-1797. doi:
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Atherosclerosis.
2018 07; 274(?):139-145. doi:
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The Journal of pharmacology and experimental therapeutics.
2018 06; 365(3):688-699. doi:
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Neurological research.
2018 May; 40(5):391-397. doi:
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International heart journal.
2018 Mar; 59(2):315-320. doi:
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Drug metabolism and disposition: the biological fate of chemicals.
2018 03; 46(3):259-267. doi:
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Circulation journal : official journal of the Japanese Circulation Society.
2018 02; 82(3):757-766. doi:
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Circulation journal : official journal of the Japanese Circulation Society.
2018 01; 82(2):532-540. doi:
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Journal of cellular physiology.
2018 Jan; 233(1):186-200. doi:
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Journal of atherosclerosis and thrombosis.
2018 Jan; 25(1):65-80. doi:
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Journal of cardiology.
2017 Dec; 70(6):537-544. doi:
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Biochemical and biophysical research communications.
2017 11; 493(2):921-927. doi:
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Journal of pharmaceutical sciences.
2017 09; 106(9):2566-2575. doi:
10.1016/j.xphs.2017.04.040. [PMID: 28456721] - Nobuhisa Hagiwara, Erisa Kawada-Watanabe, Ryo Koyanagi, Hiroyuki Arashi, Junichi Yamaguchi, Koichi Nakao, Tetsuya Tobaru, Hiroyuki Tanaka, Toshiaki Oka, Yasuhiro Endoh, Katsumi Saito, Tatsuro Uchida, Kunihiko Matsui, Hiroshi Ogawa. Low-density lipoprotein cholesterol targeting with pitavastatin + ezetimibe for patients with acute coronary syndrome and dyslipidaemia: the HIJ-PROPER study, a prospective, open-label, randomized trial.
European heart journal.
2017 Aug; 38(29):2264-2276. doi:
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Scientific reports.
2017 07; 7(1):5410. doi:
10.1038/s41598-017-05595-4. [PMID: 28710496] - Young Joon Hong, Myung Ho Jeong, Jang Ho Bae, Seok Kyu Oh, Seung Woon Rha, Seung Ho Hur, Sung Yun Lee, Sang Wook Kim, Kwang Soo Cha, In Ho Chae, Tae Hoon Ahn, Kee Sik Kim. Efficacy and safety of pitavastatins in patients with acute myocardial infarction: Livalo in Acute Myocardial Infarction Study (LAMIS) II.
The Korean journal of internal medicine.
2017 Jul; 32(4):656-667. doi:
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The lancet. HIV.
2017 07; 4(7):e284-e294. doi:
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Drug metabolism and disposition: the biological fate of chemicals.
2017 07; 45(7):721-733. doi:
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Atherosclerosis. Supplements.
2017 Jul; 27(?):e1-e9. doi:
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Journal of biomolecular structure & dynamics.
2017 May; 35(7):1529-1546. doi:
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AIDS (London, England).
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American journal of cardiovascular drugs : drugs, devices, and other interventions.
2017 Apr; 17(2):157-168. doi:
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Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir.
2017 Apr; 45(Suppl 3):13-15. doi:
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Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir.
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Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir.
2017 Apr; 45(Suppl 3):1-4. doi:
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Clinical therapeutics.
2017 Mar; 39(3):620-629. doi:
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Journal of cardiology.
2017 03; 69(3):536-541. doi:
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Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2017 Mar; 1046(?):218-225. doi:
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PloS one.
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Mediators of inflammation.
2017; 2017(?):2582745. doi:
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International journal of cardiology.
2016 Dec; 225(?):332-336. doi:
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Journal of pharmaceutical and biomedical analysis.
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