terbinafine hydrochloride (BioDeep_00000858548)
代谢物信息卡片
terbinafine hydrochloride
化学式: C21H26ClN (327.1753666000001)
中文名称: 盐酸特比萘芬
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(C)(C)C#CC=CCN(C)CC1=CC=CC2=CC=CC=C21.Cl
InChI: 1H/b9-5+
描述信息
D000890 - Anti-Infective Agents > D000935 - Antifungal Agents
C254 - Anti-Infective Agent > C514 - Antifungal Agent
D004791 - Enzyme Inhibitors
Terbinafine hydrochloride (TDT 067 hydrochloride) is an orally active and potent antifungal agent. Terbinafine hydrochloride is a potent non-competitive inhibitor of squalene epoxidase from Candida, with a Ki of 30 nM. Terbinafine hydrochloride also shows antibacterial activity against certain Gram-positive and Gram-negative bacteria[1][2][3]. Terbinafine hydrochloride is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
同义名列表
2 个代谢物同义名
数据库引用编号
7 个数据库交叉引用编号
- ChEBI: CHEBI:77614
- KEGGdrug: D02219
- PubChem: 5282481
- ChEMBL: CHEMBL1200832
- MeSH: Terbinafine
- CAS: 78628-80-5
- medchemexpress: HY-17395
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Chantal Fernandes, José Sousa-Baptista, Ana Filipa Lenha-Silva, Daniela Calheiros, Edmilson Correia, Artur Figueirinha, Lígia Salgueiro, Teresa Gonçalves. Azorean Black Tea (Camellia sinensis) Antidermatophytic and Fungicidal Properties.
Molecules (Basel, Switzerland).
2023 Nov; 28(23):. doi:
10.3390/molecules28237775. [PMID: 38067505] - Hamdy Abdelkader, Asmaa Abd El-Wahab, Ahmed Osama El-Gendy, Heba A Abou-Taleb. Formulation and optimization of lipid- and Poloxamer-tagged niosomes for dermal delivery of terbinafine: preparation, evaluation, and in vitro antifungal activity.
Pharmaceutical development and technology.
2023 Sep; ?(?):1-8. doi:
10.1080/10837450.2023.2255889. [PMID: 37664988] - Liangjian Ma, Wunan Huang, Xiaolei Liang, Guannan Bai, Xiaochen Wang, Hua Jiang, Yang Xin, Lidan Hu, Xiangjun Chen, Chang Liu. Inhibition of squalene epoxidase linking with PI3K/AKT signaling pathway suppresses endometrial cancer.
Cancer science.
2023 Jul; ?(?):. doi:
10.1111/cas.15900. [PMID: 37438885] - Tao Wang, Qiuxiao Wang, Yifei Zhou, Yaolin Shi, Haixiang Gao. The Effect of Terbinafine and Its Ionic Salts on Certain Fungal Plant Pathogens.
Molecules (Basel, Switzerland).
2023 Jun; 28(12):. doi:
10.3390/molecules28124722. [PMID: 37375277] - Xin He, Guoqing Peng, Jianying Luo, Jian-Ping Huang, Jing Yang, Yijun Yan, Yu-Cheng Gu, Li Wang, Sheng-Xiong Huang. O-Alkylazoxymycins A-F, Naturally Occurring Azoxy-Aromatic Compounds from Streptomyces sp. Py50.
Journal of natural products.
2023 01; 86(1):176-181. doi:
10.1021/acs.jnatprod.2c00892. [PMID: 36634313] - Armando Guevara, Andréia Ferreira Nery, Márcia de Souza Carvalho Melhem, Lucas Bonfietti, Anderson Messias Rodrigues, Ferry Hagen, Jamile Ambrósio de Carvalho, Zoilo Pires de Camargo, Bruna Jacomel F de Souza Lima, Vânia Aparecida Vicente, Rosane Christine Hahn. Molecular epidemiology and clinical-laboratory aspects of chromoblastomycosis in Mato Grosso, Brazil.
Mycoses.
2022 Dec; 65(12):1146-1158. doi:
10.1111/myc.13505. [PMID: 35869803] - Chuangen Li, Yong Wang, Dabin Liu, Chi Chun Wong, Olabisi Oluwabukola Coker, Xiang Zhang, Changan Liu, Yunfei Zhou, Yali Liu, Wei Kang, Ka Fai To, Joseph Jy Sung, Jun Yu. Squalene epoxidase drives cancer cell proliferation and promotes gut dysbiosis to accelerate colorectal carcinogenesis.
Gut.
2022 11; 71(11):2253-2265. doi:
10.1136/gutjnl-2021-325851. [PMID: 35232776] - Kristoffer Nagy Skaastrup, Karen Marie Thyssen Astvad, Maiken Cavling Arendrup, Gregor Borut Ernst Jemec, Ditte Marie Lindhardt Saunte. Disinfection trials with terbinafine-susceptible and terbinafine-resistant dermatophytes.
Mycoses.
2022 Jul; 65(7):741-746. doi:
10.1111/myc.13468. [PMID: 35535729] - Prashant Gupta, Hardeep Singh Malhotra, Priyamvada Saxena, Riddhi Singh, Deeksha Shukla, Mohd Saqib Hasan, Veerendra Verma, Gopa Banerjee, Bipin Puri, Himanshu Dandu. Utility of itraconazole and terbinafine in mucormycosis: a proof-of-concept analysis.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research.
2022 04; 70(4):914-918. doi:
10.1136/jim-2021-002179. [PMID: 35078866] - Can Yang, Luyao Liu, Mang Sheng, Rong Fu, Xiaodan Chen, Zhongjian Yu, Yuan Gao, Hong Zhang. Determination of terbinafine in healthy Chinese human plasma using a simple and fast LC-MS/MS method and its application to a bioequivalence study.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2022 Feb; 1191(?):123116. doi:
10.1016/j.jchromb.2022.123116. [PMID: 35063863] - Jing Li, Tao Yang, Qihong Wang, Yuedan Li, Haiyan Wu, Mei Zhang, Hong Qi, Hongxin Zhang, Jinfeng Li. Upregulation of SQLE Contributes to Poor Survival in Head and Neck Squamous Cell Carcinoma.
International journal of biological sciences.
2022; 18(9):3576-3591. doi:
10.7150/ijbs.68216. [PMID: 35813482] - Michael S McEntire, Jennifer M Reinhart, Sherry K Cox, Krista A Keller. Single-dose pharmacokinetics of orally administered terbinafine in bearded dragons (Pogona vitticeps) and the antifungal susceptibility patterns of Nannizziopsis guarroi.
American journal of veterinary research.
2021 Dec; 83(3):256-263. doi:
10.2460/ajvr.21.02.0023. [PMID: 34941564] - Ananta Khurana, Aastha Agarwal, Ashutosh Singh, Kabir Sardana, Manik Ghadlinge, Diksha Agrawal, Sanjeet Panesar, Khushboo Sethia, Anuradha Chowdhary. Predicting a therapeutic cut-off serum level of itraconazole in recalcitrant tinea corporis and cruris-A prospective trial.
Mycoses.
2021 Dec; 64(12):1480-1488. doi:
10.1111/myc.13367. [PMID: 34532888] - Pannaporn Thongsuk, Rongpong Plongla, Arsa Thammahong, Jaruwan Tiewsurin, Navaporn Worasilchai, Ariya Chindamporn, Chusana Suankratay. Vascular pythiosis caused by Pythium aphanidermatum: the first case report in Asia.
European journal of medical research.
2021 Nov; 26(1):132. doi:
10.1186/s40001-021-00603-w. [PMID: 34775999] - Winfred Taylor Frazier, Zuleica M Santiago-Delgado, Kenneth C Stupka. Onychomycosis: Rapid Evidence Review.
American family physician.
2021 10; 104(4):359-367. doi:
. [PMID: 34652111] - Carlos Rojo-Solís, Daniel García-Párraga, Andrés Montesinos, María Ardiaca-García, Teresa Álvaro, Mónica Valls, Carlos Barros-García, Teresa Encinas. Pharmacokinetics of single dose oral Terbinafine in common shelducks (Tadorna tadorna).
Journal of veterinary pharmacology and therapeutics.
2021 Jul; 44(4):510-515. doi:
10.1111/jvp.12942. [PMID: 33377208] - David Eshar, Butch KuKanich, Nili Avni-Magen, Hyun Joo. TERBINAFINE PHARMACOKINETICS FOLLOWING SINGLE-DOSE ORAL ADMINISTRATION IN RED-EARED SLIDER TURTLES (TRACHEMYS SCRIPTA ELEGANS): A PILOT STUDY.
Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians.
2021 Jun; 52(2):520-528. doi:
10.1638/2020-0079. [PMID: 34130394] - Tomoka Harada, Takeshi Fukumoto, Korefumi Nakamura, Kenichiro Ohnuma, Chikako Nishigori. Successful thermotherapy combined with terbinafine hydrochloride 1\% cream for cutaneous alternariosis in a post-transplantation patient.
The Australasian journal of dermatology.
2021 May; 62(2):e323-e325. doi:
10.1111/ajd.13489. [PMID: 33070334] - Toshihide Takagi, Takato Masada, Keiko Minami, Makoto Kataoka, Ken-Ichi Izutsu, Kazuki Matsui, Shinji Yamashita. In Vitro Sensitivity Analysis of the Gastrointestinal Dissolution Profile of Weakly Basic Drugs in the Stomach-to-Intestine Fluid Changing System: Explanation for Variable Plasma Exposure after Oral Administration.
Molecular pharmaceutics.
2021 04; 18(4):1711-1719. doi:
10.1021/acs.molpharmaceut.0c01207. [PMID: 33629861] - Rebecca H Hardman, Sherry Cox, Sherri Doro Reinsch, Heather Coarsey Schwartz, Sandy Skeba, Dale McGinnity, Marcy J Souza, Debra L Miller. EFFICACY OF SUBCUTANEOUS IMPLANTS TO PROVIDE CONTINUOUS PLASMA TERBINAFINE IN HELLBENDERS (CRYPTOBRANCHUS ALLEGANIENSI) FOR FUTURE PROPHYLACTIC USE AGAINST CHYTRIDIOMYCOSIS.
Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians.
2021 Apr; 52(1):300-305. doi:
10.1638/2020-0158. [PMID: 33827189] - Carla Bustios Sanchez, Julia Sumire Umeres, Carmen Asato Higa, Victor Monge Zapata. [Terbinafine-induced liver toxicity in the context of a SARS-CoV-2 pandemic: a case report].
Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru.
2021 Apr; 41(2):107-111. doi:
NULL. [PMID: 34724692] - Julia J Shen, Maiken C Arendrup, Gregor B E Jemec, Ditte Marie L Saunte. Photodynamic therapy: A treatment option for terbinafine resistant Trichophyton species.
Photodiagnosis and photodynamic therapy.
2021 Mar; 33(?):102169. doi:
10.1016/j.pdpdt.2020.102169. [PMID: 33497815] - Â V Pinto, J C de Oliveira, C A Costa de Medeiros, S L Silva, F O Pereira. Potentiation of antifungal activity of terbinafine by dihydrojasmone and terpinolene against dermatophytes.
Letters in applied microbiology.
2021 Mar; 72(3):292-298. doi:
10.1111/lam.13371. [PMID: 32790923] - Luana Pereira Borba-Santos, Marcio Nucci, Antonio Ferreira-Pereira, Sonia Rozental. Anti-Sporothrix activity of ibuprofen combined with antifungal.
Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology].
2021 Mar; 52(1):101-106. doi:
10.1007/s42770-020-00327-9. [PMID: 32617835] - Alicia Moreno-Sabater, Nacéra Ouali, François Chasset, Camille Frances, Patricia Senet, Caroline Faucon, Christophe Hennequin, Claude Bachmeyer. Severe onychomycosis management with oral terbinafine in a kidney transplantation setting: Clinical follow-up by image analysis.
Mycoses.
2021 Mar; 64(3):309-315. doi:
10.1111/myc.13220. [PMID: 33245794] - Niklas Worm Andersson, Simon Francis Thomsen, Jon Trærup Andersen. Exposure to terbinafine in pregnancy and risk of preterm birth, small for gestational age, low birth weight, and stillbirth: A nationwide cohort study.
Journal of the American Academy of Dermatology.
2021 Mar; 84(3):763-767. doi:
10.1016/j.jaad.2020.10.034. [PMID: 33446325] - Fatma E Abobakr, Sahar M Fayez, Vivian S Elwazzan, Wedad Sakran. Effect of Different Nail Penetration Enhancers in Solid Lipid Nanoparticles Containing Terbinafine Hydrochloride for Treatment of Onychomycosis.
AAPS PharmSciTech.
2021 Jan; 22(1):33. doi:
10.1208/s12249-020-01893-9. [PMID: 33404930] - Sercan Yıldırım, Gökhan Demirdaş, Mert Fidan, Ahmet Yaşar. Simple and Fast Determination of Terbinafine in Human Urine by Dilute and Shoot HPLC-DAD Using a Core-Shell Column.
Combinatorial chemistry & high throughput screening.
2021; 24(3):342-351. doi:
10.2174/1386207323666200709171504. [PMID: 32646357] - Mariusz Dyląg, Ewa Leniak, Sebastian Gnat, Jacek C Szepietowski, Lukasz Kozubowski. A case of anti- pityriasis versicolor therapy that preserves healthy mycobiome.
BMC dermatology.
2020 09; 20(1):9. doi:
10.1186/s12895-020-00106-x. [PMID: 32993612] - Arunima Ray, Kaustuv Mukherjee, Sharmila Thukral, Arpita Sarkar, Deepak Shankar Ray. An Unusual Case of a Dematiaceous Fungus with an Exclusive Cerebral Involvement After ABO-Incompatible Renal Transplantation.
The American journal of case reports.
2020 Aug; 21(?):e925473. doi:
10.12659/ajcr.925473. [PMID: 32859888] - Niklas Worm Andersson, Simon Francis Thomsen, Jon Trærup Andersen. Evaluation of Association Between Oral and Topical Terbinafine Use in Pregnancy and Risk of Major Malformations and Spontaneous Abortion.
JAMA dermatology.
2020 04; 156(4):375-383. doi:
10.1001/jamadermatol.2020.0142. [PMID: 32129793] - A K Gupta, N Stec, M A Bamimore, K A Foley, N H Shear, V Piguet. The efficacy and safety of pulse vs. continuous therapy for dermatophyte toenail onychomycosis.
Journal of the European Academy of Dermatology and Venereology : JEADV.
2020 Mar; 34(3):580-588. doi:
10.1111/jdv.16101. [PMID: 31746067] - Zsófia Csáky, Martina Garaiová, Marie Kodedová, Martin Valachovič, Hana Sychrová, Ivan Hapala. Squalene lipotoxicity in a lipid droplet-less yeast mutant is linked to plasma membrane dysfunction.
Yeast (Chichester, England).
2020 01; 37(1):45-62. doi:
10.1002/yea.3454. [PMID: 31826302] - Joy E Chiu, Jose Thekkiniath, Sameet Mehta, Christoph Müller, Franz Bracher, Choukri Ben Mamoun. The yeast pantothenate kinase Cab1 is a master regulator of sterol metabolism and of susceptibility to ergosterol biosynthesis inhibitors.
The Journal of biological chemistry.
2019 10; 294(40):14757-14767. doi:
10.1074/jbc.ra119.009791. [PMID: 31409644] - Chi-Hui Wang, Wei-Ti Chen, Sze-Wen Ting, Pei-Lun Sun. Subcutaneous Fungal Infection Caused by a Non-sporulating Strain of Corynespora cassiicola Successfully Treated with Terbinafine.
Mycopathologia.
2019 Oct; 184(5):691-697. doi:
10.1007/s11046-019-00393-0. [PMID: 31606812] - Ditte M L Saunte, Rasmus K Hare, Karin M Jørgensen, René Jørgensen, Mette Deleuran, Claus O Zachariae, Simon F Thomsen, Lars Bjørnskov-Halkier, Kristian Kofoed, Maiken C Arendrup. Emerging Terbinafine Resistance in Trichophyton: Clinical Characteristics, Squalene Epoxidase Gene Mutations, and a Reliable EUCAST Method for Detection.
Antimicrobial agents and chemotherapy.
2019 10; 63(10):. doi:
10.1128/aac.01126-19. [PMID: 31383665] - Abhaysingh Bhadoriya, Priyanka A Shah, Pranav S Shrivastav, Kirtikumar D Bharwad, Puran Singhal. Determination of terbinafine in human plasma using UPLC-MS/MS: Application to a bioequivalence study in healthy subjects.
Biomedical chromatography : BMC.
2019 Aug; 33(8):e4543. doi:
10.1002/bmc.4543. [PMID: 30933360] - Shari R Lipner, Richard K Scher. Onychomycosis: Treatment and prevention of recurrence.
Journal of the American Academy of Dermatology.
2019 Apr; 80(4):853-867. doi:
10.1016/j.jaad.2018.05.1260. [PMID: 29959962] - Jacob Pollier, Emmelien Vancaester, Unnikrishnan Kuzhiumparambil, Claudia E Vickers, Klaas Vandepoele, Alain Goossens, Michele Fabris. A widespread alternative squalene epoxidase participates in eukaryote steroid biosynthesis.
Nature microbiology.
2019 02; 4(2):226-233. doi:
10.1038/s41564-018-0305-5. [PMID: 30478288] - Robert John Fontana, Elizabeth Theresa Cirulli, Jiezhun Gu, David Kleiner, David Ostrov, Elizabeth Phillips, Ryan Schutte, Huiman Barnhart, Naga Chalasani, Paul Brent Watkins, Jay H Hoofnagle. The role of HLA-A*33:01 in patients with cholestatic hepatitis attributed to terbinafine.
Journal of hepatology.
2018 12; 69(6):1317-1325. doi:
10.1016/j.jhep.2018.08.004. [PMID: 30138689] - Dustyn A Barnette, Mary A Davis, Na L Dang, Anirudh S Pidugu, Tyler Hughes, S Joshua Swamidass, Gunnar Boysen, Grover P Miller. Lamisil (terbinafine) toxicity: Determining pathways to bioactivation through computational and experimental approaches.
Biochemical pharmacology.
2018 10; 156(?):10-21. doi:
10.1016/j.bcp.2018.07.043. [PMID: 30076845] - S L Forster, T Real, K P Doucette, S B King. A randomized placebo-controlled trial of the efficacy and safety of a terbinafine, florfenicol and betamethasone topical ear formulation in dogs for the treatment of bacterial and/or fungal otitis externa.
BMC veterinary research.
2018 Aug; 14(1):262. doi:
10.1186/s12917-018-1589-7. [PMID: 30170597] - Begoña Miras-Moreno, Lorena Almagro, María Angeles Pedreño, Ana Belén Sabater-Jara. Effect of terbinafine on the biosynthetic pathway of isoprenoid compounds in carrot suspension cultured cells.
Plant cell reports.
2018 Jul; 37(7):1011-1019. doi:
10.1007/s00299-018-2287-4. [PMID: 29680944] - Pei-Lun Sun, Yang-Chih Lin, Yu-Hung Wu, Pei-Han Kao, Yu-Ming Ju, Yun-Chen Fan. Tinea folliculorum complicating tinea of the glabrous skin: an important yet neglected entity.
Medical mycology.
2018 Jul; 56(5):521-530. doi:
10.1093/mmy/myx086. [PMID: 29087496] - E N Ergen, S L Donaldson, M S Stratton, P G Pavlidakey, B E Elewski. Image Gallery: Molluscum contagiosum-like facial lesions in a patient with a renal transplant: deep dermatophytosis due to Trichophyton rubrum.
The British journal of dermatology.
2018 05; 178(5):e328. doi:
10.1111/bjd.16432. [PMID: 29785830] - Kenza Baline, Fouzia Hali. [Fonsecaea pedrosoi-induced chromoblastomycosis: about a case].
The Pan African medical journal.
2018; 30(?):187. doi:
10.11604/pamj.2018.30.187.5326. [PMID: 30455816] - Viral H Shah, Amee Jobanputra. Enhanced Ungual Permeation of Terbinafine HCl Delivered Through Liposome-Loaded Nail Lacquer Formulation Optimized by QbD Approach.
AAPS PharmSciTech.
2018 Jan; 19(1):213-224. doi:
10.1208/s12249-017-0831-0. [PMID: 28681334] - Renata Cougo Moraes, Anderson Ramos Carvalho, Aline Jacobi Dalla Lana, Samuel Kaiser, Bruna Pippi, Alexandre Meneghello Fuentefria, George González Ortega. In vitro synergism of a water insoluble fraction of Uncaria tomentosa combined with fluconazole and terbinafine against resistant non-Candida albicans isolates.
Pharmaceutical biology.
2017 Dec; 55(1):406-415. doi:
10.1080/13880209.2016.1242631. [PMID: 27931150] - Clémence Delteil, Nausicaa Malissen, Quentin Magis, Stéphane Ranque, Marie-Aleth Richard, Nicolas Macagno. [Pseudo-cutaneous tumor in a renal transplant patient].
Annales de pathologie.
2017 Dec; 37(6):500-502. doi:
10.1016/j.annpat.2017.10.007. [PMID: 29169837] - O N Kramer, J Albrecht. Clinical presentation of terbinafine-induced severe liver injury and the value of laboratory monitoring: a Critically Appraised Topic.
The British journal of dermatology.
2017 Nov; 177(5):1279-1284. doi:
10.1111/bjd.15854. [PMID: 28762471] - Elena Shekhova, Olaf Kniemeyer, Axel A Brakhage. Induction of Mitochondrial Reactive Oxygen Species Production by Itraconazole, Terbinafine, and Amphotericin B as a Mode of Action against Aspergillus fumigatus.
Antimicrobial agents and chemotherapy.
2017 Nov; 61(11):. doi:
10.1128/aac.00978-17. [PMID: 28848005] - L P Kane, M C Allender, G Archer, K Leister, M Rzadkowska, K Boers, M Souza, S Cox. Pharmacokinetics of nebulized and subcutaneously implanted terbinafine in cottonmouths (Agkistrodon piscivorus).
Journal of veterinary pharmacology and therapeutics.
2017 Oct; 40(5):575-579. doi:
10.1111/jvp.12406. [PMID: 28382637] - Marie Kodedová, Hana Sychrová. Synthetic antimicrobial peptides of the halictines family disturb the membrane integrity of Candida cells.
Biochimica et biophysica acta. Biomembranes.
2017 Oct; 1859(10):1851-1858. doi:
10.1016/j.bbamem.2017.06.005. [PMID: 28600071] - T J Younkin, E G Davis, B Kukanich. Pharmacokinetics of oral terbinafine in adult horses.
Journal of veterinary pharmacology and therapeutics.
2017 Aug; 40(4):342-347. doi:
10.1111/jvp.12367. [PMID: 27885696] - M S Ouédraogo, M-D Vignon-Pennamen, M Battistella, A Levy, M Feuilhade de Chauvin, A Petit. [Chromomycosis acquired in a non-tropical area: A case report].
Annales de dermatologie et de venereologie.
2017 Jun; 144(6-7):438-442. doi:
10.1016/j.annder.2017.02.006. [PMID: 28396061] - Marcy J Souza, Patrick Redig, Sherry K Cox. Plasma Concentrations of Itraconazole, Voriconazole, and Terbinafine When Delivered by an Impregnated, Subcutaneous Implant in Japanese Quail ( Coturnix japonica ).
Journal of avian medicine and surgery.
2017 Jun; 31(2):117-122. doi:
10.1647/2016-177. [PMID: 28644078] - Thorbjørn S R Jensen, Maiken C Arendrup, Christian von Buchvald, Thomas L Frandsen, Marianne Juhler, Ulrikka Nygaard. Successful Treatment of Rhino-Orbital-Cerebral Mucormycosis in a Child With Leukemia.
Journal of pediatric hematology/oncology.
2017 05; 39(4):e211-e215. doi:
10.1097/mph.0000000000000701. [PMID: 27841827] - Paola Nicoletti, Guruprasad P Aithal, Einar S Bjornsson, Raul J Andrade, Ashley Sawle, Marco Arrese, Huiman X Barnhart, Emmanuelle Bondon-Guitton, Paul H Hayashi, Fernando Bessone, Alfonso Carvajal, Ingolf Cascorbi, Elizabeth T Cirulli, Naga Chalasani, Anita Conforti, Sally A Coulthard, Mark J Daly, Christopher P Day, John F Dillon, Robert J Fontana, Jane I Grove, Pär Hallberg, Nelia Hernández, Luisa Ibáñez, Gerd A Kullak-Ublick, Tarja Laitinen, Dominique Larrey, M Isabel Lucena, Anke H Maitland-van der Zee, Jennifer H Martin, Mariam Molokhia, Munir Pirmohamed, Elizabeth E Powell, Shengying Qin, Jose Serrano, Camilla Stephens, Andrew Stolz, Mia Wadelius, Paul B Watkins, Aris Floratos, Yufeng Shen, Matthew R Nelson, Thomas J Urban, Ann K Daly. Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study.
Gastroenterology.
2017 04; 152(5):1078-1089. doi:
10.1053/j.gastro.2016.12.016. [PMID: 28043905] - S A Ahmed, W Hofmüller, M Seibold, G S de Hoog, H Harak, I Tammer, A D van Diepeningen, W Behrens-Baumann. Tintelnotia, a new genus in Phaeosphaeriaceae harbouring agents of cornea and nail infections in humans.
Mycoses.
2017 Apr; 60(4):244-253. doi:
10.1111/myc.12588. [PMID: 27910191] - Akiko Mikami, Satoko Hori, Hisakazu Ohtani, Yasufumi Sawada. Analysis of the Mechanism of Prolonged Persistence of Drug Interaction between Terbinafine and Amitriptyline or Nortriptyline.
Biological & pharmaceutical bulletin.
2017; 40(7):1010-1020. doi:
10.1248/bpb.b16-01004. [PMID: 28674244] - Yasemin Oz, Iman Qoraan, Ali Oz, Ilknur Balta. Prevalence and epidemiology of tinea pedis and toenail onychomycosis and antifungal susceptibility of the causative agents in patients with type 2 diabetes in Turkey.
International journal of dermatology.
2017 Jan; 56(1):68-74. doi:
10.1111/ijd.13402. [PMID: 27667305] - J S Valente, A O S Fonseca, L B Denardi, V S Dal Ben, F S Maia Filho, C G Zambrano, C Q Braga, S H Alves, S A Botton, D I Brayer Pereira. In vitro activity of antifungals in combination with essential oils against the oomycete Pythium insidiosum.
Journal of applied microbiology.
2016 Oct; 121(4):998-1003. doi:
10.1111/jam.13234. [PMID: 27417677] - V K Corrigan, A M Legendre, L J Wheat, R Mullis, B Johnson, D A Bemis, L Cepero. Treatment of Disseminated Aspergillosis with Posaconazole in 10 Dogs.
Journal of veterinary internal medicine.
2016 Jan; 30(1):167-73. doi:
10.1111/jvim.13795. [PMID: 26566711] - Jacqueline R Gimmler, Amelia G White, Robert A Kennis, Crisanta Cruz-Espindola, Dawn M Boothe. Determining canine skin concentrations of terbinafine to guide the treatment of Malassezia dermatitis.
Veterinary dermatology.
2015 Dec; 26(6):411-6, e95. doi:
10.1111/vde.12245. [PMID: 26286855] - T Auvinen, R Tiihonen, M Soini, M Wangel, A Sipponen, J J Jokinen. Efficacy of topical resin lacquer, amorolfine and oral terbinafine for treating toenail onychomycosis: a prospective, randomized, controlled, investigator-blinded, parallel-group clinical trial.
The British journal of dermatology.
2015 Oct; 173(4):940-8. doi:
10.1111/bjd.13934. [PMID: 26036329] - E Drozdíková, M Garaiová, Z Csáky, M Obernauerová, I Hapala. Production of squalene by lactose-fermenting yeast Kluyveromyces lactis with reduced squalene epoxidase activity.
Letters in applied microbiology.
2015 Jul; 61(1):77-84. doi:
10.1111/lam.12425. [PMID: 25864715] - Tuukka Saarikoski, Teijo I Saari, Nora M Hagelberg, Janne T Backman, Pertti J Neuvonen, Mika Scheinin, Klaus T Olkkola, Kari Laine. Effects of terbinafine and itraconazole on the pharmacokinetics of orally administered tramadol.
European journal of clinical pharmacology.
2015 Mar; 71(3):321-7. doi:
10.1007/s00228-014-1799-2. [PMID: 25560051] - Kalman Filanovsky, Erica Sigler, Lev Shvidel. Thrombotic thrombocytopenic purpura following terbinafine therapy.
Journal of clinical apheresis.
2015 Feb; 30(1):58-9. doi:
10.1002/jca.21359. [PMID: 25255772] - Danielle Tolomeotti, Marialba Avezum Alves de Castro-Prado, Juliane Rocha de Sant'Anna, Ana Beatriz Tozzo Martins, Valter Augusto Della-Rosa. Genotoxic evaluation of terbinafine in human lymphocytes in vitro.
Drug and chemical toxicology.
2015; 38(3):306-11. doi:
10.3109/01480545.2014.959174. [PMID: 25231917] - Kartik Kumar, Anna Gill, Rachelle Shafei, Janine L Wright. A curious case of cholestasis: oral terbinafine associated with cholestatic jaundice and subsequent erythema nodosum.
BMJ case reports.
2014 Dec; 2014(?):. doi:
10.1136/bcr-2014-205331. [PMID: 25480138] - R E Cardoza, M G Malmierca, S Gutiérrez. Overexpression of erg1 gene in Trichoderma harzianum CECT 2413: effect on the induction of tomato defence-related genes.
Journal of applied microbiology.
2014 Sep; 117(3):812-23. doi:
10.1111/jam.12574. [PMID: 24925373] - Meryem Sedef Erdal, Ayca Yıldız Peköz, Buket Aksu, Ahmet Araman. Impacts of chemical enhancers on skin permeation and deposition of terbinafine.
Pharmaceutical development and technology.
2014 Aug; 19(5):565-70. doi:
10.3109/10837450.2013.813538. [PMID: 23841559] - Abdul Rauf Sheikh, Ian Westley, Benedetta Sallustio, John D Horowitz, John F Beltrame. Interaction of terbinafine (anti-fungal agent) with perhexiline: a case report.
Heart, lung & circulation.
2014 Jun; 23(6):e149-51. doi:
10.1016/j.hlc.2013.11.012. [PMID: 24373912] - Hongbo Yan, Yunying Zhao, Linghuo Jiang. The putative transcription factor CaRtg3 is involved in tolerance to cations and antifungal drugs as well as serum-induced filamentation in Candida albicans.
FEMS yeast research.
2014 Jun; 14(4):614-23. doi:
10.1111/1567-1364.12148. [PMID: 24606409] - Martina Garaiová, Veronika Zambojová, Zuzana Simová, Peter Griač, Ivan Hapala. Squalene epoxidase as a target for manipulation of squalene levels in the yeast Saccharomyces cerevisiae.
FEMS yeast research.
2014 Mar; 14(2):310-23. doi:
10.1111/1567-1364.12107. [PMID: 24119181] - Marius Irimie, Alexandru Tătaru, Alexandru Oantă, Marius Moga. In vitro susceptibility of dermatophytes isolated from patients with end-stage renal disease: a case-control study.
Mycoses.
2014 Mar; 57(3):129-34. doi:
10.1111/myc.12114. [PMID: 23889207] - Michael J Dolton, Vidya Perera, Lisa G Pont, Andrew J McLachlan. Terbinafine in combination with other antifungal agents for treatment of resistant or refractory mycoses: investigating optimal dosing regimens using a physiologically based pharmacokinetic model.
Antimicrobial agents and chemotherapy.
2014; 58(1):48-54. doi:
10.1128/aac.02006-13. [PMID: 24126579] - María Victoria Rodriguez, Maximiliano A Sortino, Juan J Ivancovich, José M Pellegrino, Laura S Favier, Marcela P Raimondi, Martha A Gattuso, Susana A Zacchino. Detection of synergistic combinations of Baccharis extracts with terbinafine against Trichophyton rubrum with high throughput screening synergy assay (HTSS) followed by 3D graphs. Behavior of some of their components.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2013 Oct; 20(13):1230-9. doi:
10.1016/j.phymed.2013.06.015. [PMID: 23906773] - F Belal, M K Sharaf El-Din, M I Eid, R M El-Gamal. Spectrofluorimetric determination of terbinafine hydrochloride and linezolid in their dosage forms and human plasma.
Journal of fluorescence.
2013 Sep; 23(5):1077-87. doi:
10.1007/s10895-013-1237-3. [PMID: 23722995] - Erika E Evans, Lee C Emery, Sherry K Cox, Marcy J Souza. Pharmacokinetics of terbinafine after oral administration of a single dose to Hispaniolan Amazon parrots (Amazona ventralis).
American journal of veterinary research.
2013 Jun; 74(6):835-8. doi:
10.2460/ajvr.74.6.835. [PMID: 23718650] - Harshad Vaghasiya, Abhinesh Kumar, Krutika Sawant. Development of solid lipid nanoparticles based controlled release system for topical delivery of terbinafine hydrochloride.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
2013 May; 49(2):311-22. doi:
10.1016/j.ejps.2013.03.013. [PMID: 23557842] - Minh T Ta, Tamar S Kapterian, Weihua Fei, Ximing Du, Andrew J Brown, Ian W Dawes, Hongyuan Yang. Accumulation of squalene is associated with the clustering of lipid droplets.
The FEBS journal.
2012 Nov; 279(22):4231-44. doi:
10.1111/febs.12015. [PMID: 23013491] - Bárdur Sigurgeirsson, Mahmoud Ghannoum. Therapeutic potential of TDT 067 (terbinafine in Transfersome): a carrier-based dosage form of terbinafine for onychomycosis.
Expert opinion on investigational drugs.
2012 Oct; 21(10):1549-62. doi:
10.1517/13543784.2012.711315. [PMID: 22876754] - Lee C Emery, Sherry K Cox, Marcy J Souza. Pharmacokinetics of nebulized terbinafine in Hispaniolan Amazon parrots (Amazona ventralis).
Journal of avian medicine and surgery.
2012 Sep; 26(3):161-6. doi:
10.1647/2012-003r.1. [PMID: 23156978] - Caroline Rezende Guerra, Kelly Ishida, Marcio Nucci, Sonia Rozental. Terbinafine inhibits Cryptococcus neoformans growth and modulates fungal morphology.
Memorias do Instituto Oswaldo Cruz.
2012 Aug; 107(5):582-90. doi:
10.1590/s0074-02762012000500003. [PMID: 22850947] - Ang Wang, Huanzhong Ding, Yiming Liu, Yan Gao, Zhenling Zeng. Single dose pharmacokinetics of terbinafine in cats.
Journal of feline medicine and surgery.
2012 Aug; 14(8):540-4. doi:
10.1177/1098612x12442280. [PMID: 22403416] - Chad W Schmiedt, Meri Stratton-Phelps, Bryan T Torres, Dennis Bell, Elizabeth W Uhl, Shawn Zimmerman, Jason Epstein, Karen K Cornell. Treatment of intestinal pythiosis in a dog with a combination of marginal excision, chemotherapy, and immunotherapy.
Journal of the American Veterinary Medical Association.
2012 Aug; 241(3):358-63. doi:
10.2460/javma.241.3.358. [PMID: 22812473] - M Ghannoum, N Isham, W Henry, H-A Kroon, S Yurdakul. Evaluation of the morphological effects of TDT 067 (terbinafine in Transfersome) and conventional terbinafine on dermatophyte hyphae in vitro and in vivo.
Antimicrobial agents and chemotherapy.
2012 May; 56(5):2530-4. doi:
10.1128/aac.05998-11. [PMID: 22354309] - Eliza Mayer, Ofer Ben Izhak, Reuven Bergman. Histopathological periodic acid-schiff stains of nail clippings as a second-line diagnostic tool in onychomycosis.
The American Journal of dermatopathology.
2012 May; 34(3):270-3. doi:
10.1097/dad.0b013e318234cc49. [PMID: 22452952] - Gavin L Olsen, Krysta L Deitz, Heather A Flaherty, Shawn R Lockhart, Steven F Hurst, Joseph S Haynes. Use of terbinafine in the treatment protocol of intestinal Cryptococcus neoformans in a dog.
Journal of the American Animal Hospital Association.
2012 May; 48(3):216-20. doi:
10.5326/jaaha-ms-5813. [PMID: 22474053] - Yue Fang, Lingling Hu, Xin Zhou, Wurentuya Jaiseng, Ben Zhang, Tomonori Takami, Takayoshi Kuno. A genomewide screen in Schizosaccharomyces pombe for genes affecting the sensitivity of antifungal drugs that target ergosterol biosynthesis.
Antimicrobial agents and chemotherapy.
2012 Apr; 56(4):1949-59. doi:
10.1128/aac.05126-11. [PMID: 22252817] - Damiano Tambasco, Marco D'Ettorre, Roberto Bracaglia, Guido Massi, Brunella Posteraro, Riccardo Torelli, Clara De Simone, Rodolfo Capizzi. A suspected squamous cell carcinoma in a renal transplant recipient revealing a rare cutaneous phaeohyphomycosis by Alternaria infectoria.
Journal of cutaneous medicine and surgery.
2012 Mar; 16(2):131-4. doi:
10.2310/7750.2011.10129. [PMID: 22513067] - Ying-Chen Chen, Der-Zen Liu, Jun-Jen Liu, Tsung-Wei Chang, Hsiu-O Ho, Ming-Thau Sheu. Development of terbinafine solid lipid nanoparticles as a topical delivery system.
International journal of nanomedicine.
2012; 7(?):4409-18. doi:
10.2147/ijn.s33682. [PMID: 22923986] - Gero Steinberg. Cytoplasmic fungal lipases release fungicides from ultra-deformable vesicular drug carriers.
PloS one.
2012; 7(5):e38181. doi:
10.1371/journal.pone.0038181. [PMID: 22666476] - Jian-Ping Zhang, Yu-Hui Wei, Yan Zhou, Yu-Qing Li, Xin-An Wu. Ethosomes, binary ethosomes and transfersomes of terbinafine hydrochloride: a comparative study.
Archives of pharmacal research.
2012 Jan; 35(1):109-17. doi:
10.1007/s12272-012-0112-0. [PMID: 22297749] - Mary R Sakai, Elizabeth R May, Paula M Imerman, Charles Felz, Timothy A Day, Steve A Carlson, James O Noxon. Terbinafine pharmacokinetics after single dose oral administration in the dog.
Veterinary dermatology.
2011 Dec; 22(6):528-34. doi:
10.1111/j.1365-3164.2011.00985.x. [PMID: 21599768] - Eleni Naziri, Fani Mantzouridou, Maria Z Tsimidou. Enhanced squalene production by wild-type Saccharomyces cerevisiae strains using safe chemical means.
Journal of agricultural and food chemistry.
2011 Sep; 59(18):9980-9. doi:
10.1021/jf201328a. [PMID: 21806066] - Rita Pagiotti, Paola Angelini, Andrea Rubini, Bruno Tirillini, Bruno Granetti, Roberto Venanzoni. Identification and characterisation of human pathogenic filamentous fungi and susceptibility to Thymus schimperi essential oil.
Mycoses.
2011 Sep; 54(5):e364-76. doi:
10.1111/j.1439-0507.2010.01926.x. [PMID: 20633233] - Gui X Lv, Yi P Ge, Yong N Shen, Min Li, X Zhang, Hao Chen, S Deng, G Sybren de Hoog, Wei D Liu. Phaeohyphomycosis caused by a plant pathogen, Corynespora cassiicola.
Medical mycology.
2011 Aug; 49(6):657-61. doi:
10.3109/13693786.2011.553635. [PMID: 21281061]