1,2,2,2-tetrafluoroethane (BioDeep_00000858417)

   


代谢物信息卡片


1,2,2,2-tetrafluoroethane

  化学式: C2H2F4 (102.0093)
中文名称: 诺氟烷, 1,1,1,2-四氟乙烷
  谱图信息: 最多检出来源 () %

分子结构信息

SMILES: C(C(F)(F)F)F
InChI: InChI=1S/C2H2F4/c3-1-2(4,5)6/h1H2

描述信息

D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D000777 - Anesthetics

同义名列表

3 个代谢物同义名

1,2,2,2-tetrafluoroethane; 1,1,1,2-Tetrafluoroethane; 1,1,1,2-Tetrafluoroethane



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome()

BioCyc()

PlantCyc()

代谢反应

个相关的代谢反应过程信息。

Reactome()

BioCyc()

WikiPathways()

Plant Reactome()

INOH()

PlantCyc()

COVID-19 Disease Map()

PathBank()

PharmGKB()

个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Wenhua Wang, Zhengwei Huang, Ke Xue, Jiaye Li, Wenhao Wang, Jingyi Ma, Cheng Ma, Xuequn Bai, Ying Huang, Xin Pan, Chuanbin Wu. Development of Aggregation-Caused Quenching Probe-Loaded Pressurized Metered-Dose Inhalers with Fluorescence Tracking Potentials. AAPS PharmSciTech. 2020 Oct; 21(8):296. doi: 10.1208/s12249-020-01782-1. [PMID: 33099699]
  • Hui Wang, Penny Tan, David Barona, Grace Li, Susan Hoe, David Lechuga-Ballesteros, David S Nobes, Reinhard Vehring. Characterization of the suspension stability of pharmaceuticals using a shadowgraphic imaging method. International journal of pharmaceutics. 2018 Sep; 548(1):128-138. doi: 10.1016/j.ijpharm.2018.06.053. [PMID: 29959088]
  • Andres Espadín, Lenin Tamay De Dios, Erika Ruvalcaba, Josefina Valadez-García, Cristina Velasquillo, Ismael Bustos-Jaimes, Humberto Vázquez-Torres, Miquel Gimeno, Keiko Shirai. Production and characterization of a nanocomposite of highly crystalline nanowhiskers from biologically extracted chitin in enzymatic poly(ε-caprolactone). Carbohydrate polymers. 2018 Feb; 181(?):684-692. doi: 10.1016/j.carbpol.2017.11.094. [PMID: 29254023]
  • Guadalupe Villa-Lerma, Humberto González-Márquez, Miquel Gimeno, Stéphane Trombotto, Laurent David, Shinsuke Ifuku, Keiko Shirai. Enzymatic hydrolysis of chitin pretreated by rapid depressurization from supercritical 1,1,1,2-tetrafluoroethane toward highly acetylated oligosaccharides. Bioresource technology. 2016 Jun; 209(?):180-6. doi: 10.1016/j.biortech.2016.02.138. [PMID: 26970920]
  • Lena Ernstgård, Bengt Sjögren, Sara Gunnare, Gunnar Johanson. Blood and exhaled air can be used for biomonitoring of hydrofluorocarbon exposure. Toxicology letters. 2014 Feb; 225(1):102-9. doi: 10.1016/j.toxlet.2013.11.026. [PMID: 24296009]
  • Lena Ernstgård, Birger Lind, Melvin E Andersen, Gunnar Johanson. Liquid-air partition coefficients of 1,1-difluoroethane (HFC152a), 1,1,1-trifluoroethane (HFC143a), 1,1,1,2-tetrafluoroethane (HFC134a), 1,1,1,2,2-pentafluoroethane (HFC125) and 1,1,1,3,3-pentafluoropropane (HFC245fa). Journal of applied toxicology : JAT. 2010 Jan; 30(1):59-62. doi: 10.1002/jat.1473. [PMID: 19701883]
  • Y S Mok, V Demidyuk, J C Whitehead. Decomposition of hydrofluorocarbons in a dielectric-packed plasma reactor. The journal of physical chemistry. A. 2008 Jul; 112(29):6586-91. doi: 10.1021/jp8020084. [PMID: 18582026]
  • Sara Gunnare, Lena Ernstgård, Bengt Sjögren, Gunnar Johanson. Toxicokinetics of 1,1,1,2-tetrafluoroethane (HFC-134a) in male volunteers after experimental exposure. Toxicology letters. 2006 Nov; 167(1):54-65. doi: 10.1016/j.toxlet.2006.08.009. [PMID: 17030466]
  • Ester Marotta, Cristina Paradisi, Gianfranco Scorrano. An atmospheric pressure chemical ionization study of the positive and negative ion chemistry of the hydrofluorocarbons 1,1-difluoroethane (HFC-152a) and 1,1,1,2-tetrafluoroethane (HFC-134a) and of perfluoro-n-hexane (FC-72) in air plasma at atmospheric pressure. Journal of mass spectrometry : JMS. 2004 Jul; 39(7):791-801. doi: 10.1002/jms.653. [PMID: 15282758]
  • T Berlet, A Krah, U Börner, B S Gathof. Desflurane inhibits platelet function in vitro similar to halothane. European journal of anaesthesiology. 2003 Nov; 20(11):878-83. doi: 10.1017/s0265021503001418. [PMID: 14649339]
  • Takafumi Hirata. Chemically assisted laser ablation ICP mass spectrometry. Analytical chemistry. 2003 Jan; 75(2):228-33. doi: 10.1021/ac020497q. [PMID: 12553756]
  • G D Ritchie, E C Kimmel, L E Bowen, J E Reboulet, J Rossi. Acute neurobehavioral effects in rats from exposure to HFC 134a or CFC 12. Neurotoxicology. 2001 Apr; 22(2):233-48. doi: 10.1016/s0161-813x(01)00011-0. [PMID: 11405255]
  • J W Ramsdell, G L Colice, B P Ekholm, N M Klinger. Cumulative dose response study comparing HFA-134a albuterol sulfate and conventional CFC albuterol in patients with asthma. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 1998 Dec; 81(6):593-9. doi: 10.1016/s1081-1206(10)62711-1. [PMID: 9892032]
  • V W Pike, F I Aigbirhio, C A Freemantle, B C Page, C G Rhodes, S L Waters, T Jones, P Olsson, G P Ventresca, R J Tanner. Disposition of inhaled 1,1,1,2-tetrafluoroethane (HFA134A) in healthy subjects and in patients with chronic airflow limitation. Measurement by 18F-labeling and whole-body gamma-counting. Drug metabolism and disposition: the biological fate of chemicals. 1995 Aug; 23(8):832-9. doi: NULL. [PMID: 7493550]
  • S M Kirby, J Smith, G P Ventresca. Salmeterol inhaler using a non-chlorinated propellant, HFA134a: systemic pharmacodynamic activity in healthy volunteers. Thorax. 1995 Jun; 50(6):679-81. doi: 10.1136/thx.50.6.679. [PMID: 7638815]
  • S Y Monté, I Ismail, D N Mallett, C Matthews, R J Tanner. The minimal metabolism of inhaled 1,1,1,2-tetrafluoroethane to trifluoroacetic acid in man as determined by high sensitivity 19F nuclear magnetic resonance spectroscopy of urine samples. Journal of pharmaceutical and biomedical analysis. 1994 Dec; 12(12):1489-93. doi: 10.1016/0731-7085(94)00104-9. [PMID: 7696372]
  • Y Wang, M J Olson, M T Baker. Interaction of fluoroethane chlorofluorocarbon (CFC) substitutes with microsomal cytochrome P450. Stimulation of P450 activity and chlorodifluoroethene metabolism. Biochemical pharmacology. 1993 Jul; 46(1):87-94. doi: 10.1016/0006-2952(93)90351-v. [PMID: 8347140]
  • M K Ellis, L A Gowans, T Green, R J Tanner. Metabolic fate and disposition of 1,1,1,2-tetrafluoroethane (HFC134a) in rat following a single exposure by inhalation. Xenobiotica; the fate of foreign compounds in biological systems. 1993 Jul; 23(7):719-29. doi: 10.3109/00498259309166779. [PMID: 8237055]


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