Pancuronium bromide (BioDeep_00000858409)

   


代谢物信息卡片


Pancuronium dibromide

化学式: C35H60Br2N2O4 (730.291956)
中文名称: 泮库溴铵
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(=O)OC1CC2CCC3C(C2(CC1[N+]4(CCCCC4)C)C)CCC5(C3CC(C5OC(=O)C)[N+]6(CCCCC6)C)C.[Br-].[Br-]
InChI: /m0../s1

描述信息

D018373 - Peripheral Nervous System Agents > D009465 - Neuromuscular Agents > D009466 - Neuromuscular Blocking Agents
D018377 - Neurotransmitter Agents > D018678 - Cholinergic Agents > D018680 - Cholinergic Antagonists
C78281 - Agent Affecting Musculoskeletal System > C29696 - Muscle Relaxant
Pancuronium dibromide, a bis-quaternary steroid, is a neuromuscular relaxant. Pancuronium dibromide inhibits neuromuscular transmission by competing with acetylcholine for binding sites on nACh receptors. Pancuronium dibromide also inhibits cardiac muscarinic receptors and has a sympathomimetic action[1][2][3].

同义名列表

3 个代谢物同义名

Pancuronium dibromide; Pancuronium bromide; Pancuronium (dibromide)



数据库引用编号

7 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
  • Rafał Skowronek, Małgorzata Korczyńska, Joanna Kulikowska, Joanna Nowicka, Stanisława Kabiesz-Neniczka. Patient's death as a result of mistakenly injection of pancuronium. Archiwum medycyny sadowej i kryminologii. 2017 ; 67(4):254-263. doi: 10.5114/amsik.2017.75056. [PMID: 29663745]
  • Sayed Imam Mohamed Zayed. Flow injection potentiometric determination of pancuronium bromide in pharmaceutical preparation and urine samples using modified carbon paste electrodes. Chemical & pharmaceutical bulletin. 2011; 59(2):254-9. doi: 10.1248/cpb.59.254. [PMID: 21297308]
  • Young-Ah Koo, BoEun Lee, Hyun-Jung Park, JongYeob Choi, EunYoung Lee, DooSeok Choi. Altered vascular endothelial growth factor expression during GnRH antagonist protocol in women of reproductive age with normal baseline hormone profiles. Fertility and sterility. 2009 Mar; 91(3):744-8. doi: 10.1016/j.fertnstert.2007.12.068. [PMID: 18321491]
  • Elaine Campana Sanches Bornia, Erika Bando, Miguel Machinski, Monalisa Wolski Pereira, Wilson Alves-Do-Prado. Presynaptic M1, M2, and A1 receptors play roles in tetanic fade induced by pancuronium or cisatracurium. Journal of anesthesia. 2009; 23(4):513-9. doi: 10.1007/s00540-009-0790-z. [PMID: 19921360]
  • Man Liu, James P Dilger. Site selectivity of competitive antagonists for the mouse adult muscle nicotinic acetylcholine receptor. Molecular pharmacology. 2009 Jan; 75(1):166-73. doi: 10.1124/mol.108.051060. [PMID: 18842832]
  • C Motamed, P Fanen, P Feiss, K Kirov, P Duvaldestin. Dose-response effect of serum butyrylcholinesterase activity after clinical doses of pancuronium. European journal of clinical pharmacology. 2008 Nov; 64(11):1043-5. doi: 10.1007/s00228-008-0548-9. [PMID: 18766333]
  • Isabelle Streuli, Timothée Fraisse, Christine Pillet, Victoria Ibecheole, Paul Bischof, Dominique de Ziegler. Serum antimüllerian hormone levels remain stable throughout the menstrual cycle and after oral or vaginal administration of synthetic sex steroids. Fertility and sterility. 2008 Aug; 90(2):395-400. doi: 10.1016/j.fertnstert.2007.06.023. [PMID: 17919608]
  • Chih-Wei Peng, Jia-Jin Jason Chen, Chen-Li Cheng, Warren M Grill. Role of pudendal afferents in voiding efficiency in the rat. American journal of physiology. Regulatory, integrative and comparative physiology. 2008 Feb; 294(2):R660-72. doi: 10.1152/ajpregu.00270.2007. [PMID: 18077513]
  • Emad S Osman, Hanan F Khafagy, Khalda G Radwan, Abdullah M Desouky. Role of cholinesterase activity on pharmacodynamics of mivacurium preceded by pancuronium in elderly and young adults. Journal of the Egyptian Society of Parasitology. 2007 Apr; 37(1):243-55. doi: . [PMID: 17580581]
  • V P Stankov-Jovanovic, S D Nikolic-Mandic, Lj M Mandic, V D Mitic. A modification of the kinetic determination of pancuronium bromide based on its inhibitory effect on cholinesterase. Journal of clinical laboratory analysis. 2007; 21(2):124-31. doi: 10.1002/jcla.20162. [PMID: 17385680]
  • Vesna P Stankov-Jovanović, Snezana D Nikolić-Mandić, Ljuba M Mandić, Violeta D Mitić. Cholinesterase inhibition based determination of pancuronium bromide in biological samples. Analytical and bioanalytical chemistry. 2006 Aug; 385(8):1462-9. doi: 10.1007/s00216-006-0556-5. [PMID: 16804673]
  • Kiyotaka Usui, Takanori Hishinuma, Hiroaki Yamaguchi, Toshihide Saga, Toshihiro Wagatsuma, Kunihiko Hoshi, Naoki Tachiiri, Kuniaki Miura, Junichi Goto. Simultaneous determination of pancuronium, vecuronium and their related compounds using LC-ESI-MS. Legal medicine (Tokyo, Japan). 2006 May; 8(3):166-71. doi: 10.1016/j.legalmed.2006.02.001. [PMID: 16621652]
  • C Motamed, K Kirov, X Combes, P Feiss, P Duvaldestin. Interaction between mivacurium and pancuronium: impact of the order of administration. European journal of clinical pharmacology. 2005 May; 61(3):175-7. doi: 10.1007/s00228-005-0905-x. [PMID: 15824913]
  • Lori Olivieri, Gilles Plourde. Prolonged (more than ten hours) neuromuscular blockade after cardiac surgery: report of two cases. Canadian journal of anaesthesia = Journal canadien d'anesthesie. 2005 Jan; 52(1):88-93. doi: 10.1007/bf03018587. [PMID: 15625263]
  • N Scheffold, B Heinz, H Albrecht, A Pickert, J Cyran. [Strychnine poisoning]. Deutsche medizinische Wochenschrift (1946). 2004 Oct; 129(42):2236-8. doi: 10.1055/s-2004-831869. [PMID: 15483758]
  • Cyrus Motamed, Riad Menad, Robert Farinotti, Krassen Kirov, Xavier Combes, Daniel Bouleau, Pierre Feiss, Philippe Duvaldestin. Potentiation of mivacurium blockade by low dose of pancuronium: a pharmacokinetic study. Anesthesiology. 2003 May; 98(5):1057-62. doi: 10.1097/00000542-200305000-00006. [PMID: 12717125]
  • Salmaan Kanji, Jeffrey F Barletta, James J Janisse, James A Kruse, John W Devlin. Tachyphylaxis associated with continuous cisatracurium versus pancuronium therapy. Pharmacotherapy. 2002 Jul; 22(7):823-30. doi: 10.1592/phco.22.11.823.33625. [PMID: 12126215]
  • Tomasz Rechberger, Włodzimierz Baranowski, Michał Bogusiewicz, Krzysztof Postawski, Artur J Jakimiuk, Jacek Tomaszewski, Beata Kulik-Rechberger, Jerzy A Jakowicki. Serum concentrations of markers of type I collagen metabolism in women taking monophasic oral contraceptives. Ginekologia polska. 2002 Feb; 73(2):81-6. doi: NULL. [PMID: 12001776]
  • C H M Kerskes, K J Lusthof, P G M Zweipfenning, J P Franke. The detection and identification of quaternary nitrogen muscle relaxants in biological fluids and tissues by ion-trap LC-ESI-MS. Journal of analytical toxicology. 2002 Jan; 26(1):29-34. doi: 10.1093/jat/26.1.29. [PMID: 11890177]
  • K Uryu, K Minami, N Yanagihara, K Hara, Y Toyohira, F Izumi, A Shigematsu. Inhibition by neuromuscular blocking drugs of norepinephrine transporter in cultured bovine adrenal medullary cells. Anesthesia and analgesia. 2000 Sep; 91(3):546-51. doi: 10.1097/00000539-200009000-00008. [PMID: 10960373]
  • C Motamed, K Kirov, T Lieutaud, P Duvaldestin. The mechanism of pancuronium potentiation of mivacurium block: use of the isolated-arm technique. Anesthesia and analgesia. 2000 Sep; 91(3):732-5. doi: 10.1097/00000539-200009000-00044. [PMID: 10960409]
  • A G McKenzie. Prelude to pancuronium and vecuronium. Anaesthesia. 2000 Jun; 55(6):551-6. doi: 10.1046/j.1365-2044.2000.01423.x. [PMID: 10866718]
  • K Koishi, Y Ooe, A Hirata, H Kimura, M Izawa. [Respiratory muscle weakness after prolonged use of hydrocortisone and pancuronium bromide]. Masui. The Japanese journal of anesthesiology. 2000 Jan; 49(1):72-4. doi: NULL. [PMID: 10689850]
  • N Abuaf, B Rajoely, E Ghazouani, D A Levy, C Pecquet, H Chabane, F Leynadier. Validation of a flow cytometric assay detecting in vitro basophil activation for the diagnosis of muscle relaxant allergy. The Journal of allergy and clinical immunology. 1999 Aug; 104(2 Pt 1):411-8. doi: 10.1016/s0091-6749(99)70386-6. [PMID: 10452764]
  • K Sato, K Windisch, I Matko, E S Vizi. Effects of non-depolarizing neuromuscular blocking agents on norepinephrine release from human atrial tissue obtained during cardiac surgery. British journal of anaesthesia. 1999 Jun; 82(6):904-9. doi: 10.1093/bja/82.6.904. [PMID: 10562787]
  • M Lluch Fernández, A Vallejo Uclés, F Vallejo Cantarero, F Zurita Castro, E Huelva Ramírez, C Moreno Carmona. [Anesthesia and intraoperative treatment in 2 cases of simultaneous liver, pancreas, and kidney transplantation]. Revista espanola de anestesiologia y reanimacion. 1999 May; 46(5):215-8. doi: NULL. [PMID: 10379188]
  • E Freye, H Dehnen-Seipel, L Latasch, M Behler, O H Wilder-Smith. Slow EEG-power spectra correlate with haemodynamic changes during laryngoscopy and intubation following induction with fentanyl or sufentanil. Acta anaesthesiologica Belgica. 1999; 50(2):71-6. doi: NULL. [PMID: 10418645]
  • M Brinkmann, M Günnicker, U Freund, M Schieffer, J Peters. [Histamine plasma concentration and cardiovascular effects of non-depolarizing muscle relaxants: comparison of atracurium, vecuronium, pancuronium and pipecuronium in coronary surgical patients at risk]. Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS. 1998 Jun; 33(6):362-6. doi: 10.1055/s-2007-994264. [PMID: 9689393]
  • A Dönmez, Z Kayhan, A Pirat, S Sekerci. Anesthetic management of coronary artery bypass operation in renal transplant recipients. Transplantation proceedings. 1998 May; 30(3):790-2. doi: 10.1016/s0041-1345(98)00050-5. [PMID: 9595100]
  • J R Sneyd. Extended neuromuscular blockade with mivacurium following pancuronium. European journal of anaesthesiology. 1996 Sep; 13(5):483-4. doi: 10.1046/j.1365-2346.1996.00989.x. [PMID: 8889423]
  • S Bjurström, J Carlsten, L Jönsson. Absence of skeletal muscle lesions after experimental restraint stress induced by pancuronium in normal and stress-susceptible pigs. Zentralblatt fur Veterinarmedizin. Reihe A. 1996 May; 43(3):129-38. doi: 10.1111/j.1439-0442.1996.tb00437.x. [PMID: 8693835]
  • F Xue, L Luo, B Sun, Q Zou. [The pharmacokinetics of pancuronium bromide in infants, children and adults]. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae. 1996 Apr; 18(2):121-5. doi: NULL. [PMID: 9208601]
  • C M Coenen, C M Thomas, G F Borm, J M Hollanders, R Rolland. Changes in androgens during treatment with four low-dose contraceptives. Contraception. 1996 Mar; 53(3):171-6. doi: 10.1016/0010-7824(96)00006-6. [PMID: 8689882]
  • F Xue, B Sun, Q Zou, L Luo. Effects of enflurane and isoflurane anesthesia on the pharmacokinetics of pancuronium in adult patients. Chinese medical journal. 1996 Mar; 109(3):233-7. doi: NULL. [PMID: 8758316]
  • T Higashi, N Kamo, H Naitou, K Tada. [Anesthesia for cesarean section: drug transfer to fetus during anesthesia]. Masui. The Japanese journal of anesthesiology. 1996 Jan; 45(1):96-8. doi: NULL. [PMID: 8865733]
  • C A Shanks, M J Avram, T C Krejcie, T K Henthorn. Calculation of an effect compartment rate constant using recovery indices obtained with an isolated arm technique. British journal of anaesthesia. 1995 Jul; 75(1):109-12. doi: 10.1093/bja/75.1.109. [PMID: 7669449]
  • M Kimura, I Kimura, M Muroi, H Nojima, P V Diwan. Depolarizing neuromuscular blocking action of coryneine derived from aconite root in isolated mouse phrenic nerve-diaphragm muscles. Biological & pharmaceutical bulletin. 1995 May; 18(5):691-5. doi: 10.1248/bpb.18.691. [PMID: 7492984]
  • M J Murray, D B Coursin, P E Scuderi, G Kamath, D S Prough, D M Howard, M A Abou-Donia. Double-blind, randomized, multicenter study of doxacurium vs. pancuronium in intensive care unit patients who require neuromuscular-blocking agents. Critical care medicine. 1995 Mar; 23(3):450-8. doi: 10.1097/00003246-199503000-00007. [PMID: 7874894]
  • P J Kulka, M Tryba, M Zenz. Dose-response effects of intravenous clonidine on stress response during induction of anesthesia in coronary artery bypass graft patients. Anesthesia and analgesia. 1995 Feb; 80(2):263-8. doi: 10.1097/00000539-199502000-00011. [PMID: 7818111]
  • J M Elliot, J F Bion. The use of neuromuscular blocking drugs in intensive care practice. Acta anaesthesiologica Scandinavica. Supplementum. 1995; 106(?):70-82. doi: 10.1111/j.1399-6576.1995.tb04315.x. [PMID: 8533552]
  • M Behne, V Lischke, F Asskali, S Probst, R Hermann, J Vettermann. Midazolam does not antagonize fentanyl-mediated analgesia in surgical patients. Journal of clinical anesthesia. 1994 Nov; 6(6):481-6. doi: 10.1016/0952-8180(94)90088-4. [PMID: 7880511]
  • H Böhrer, H Schmidt, A Bach, E Martin, B Kohl, K Bolsen, G Goerz. Porphyrinogenic effects of atracurium, vecuronium, and pancuronium in a primed rat model. Laboratory animal science. 1994 Aug; 44(4):326-30. doi: NULL. [PMID: 7983842]
  • E Giostra, M R Magistris, G Pizzolato, J Cox, J C Chevrolet. Neuromuscular disorder in intensive care unit patients treated with pancuronium bromide. Occurrence in a cluster group of seven patients and two sporadic cases, with electrophysiologic and histologic examination. Chest. 1994 Jul; 106(1):210-20. doi: 10.1378/chest.106.1.210. [PMID: 8020274]
  • P A Iaizzo, D J Wedel. Response to succinylcholine in porcine malignant hyperthermia. Anesthesia and analgesia. 1994 Jul; 79(1):143-51. doi: 10.1213/00000539-199407000-00027. [PMID: 8010426]
  • S P Ionides, M G Weiss, M Angelopoulos, T F Myers, R J Handa. Plasma beta-endorphin concentrations and analgesia-muscle relaxation in the newborn infant supported by mechanical ventilation. The Journal of pediatrics. 1994 Jul; 125(1):113-6. doi: 10.1016/s0022-3476(94)70136-9. [PMID: 8021759]
  • P P Neidhart, P Champion, J Vogel, E K Zsigmond, E Tassonyi. A comparison of pipecuronium with pancuronium on haemodynamic variables and plasma catecholamines in coronary artery bypass patients. Canadian journal of anaesthesia = Journal canadien d'anesthesie. 1994 Jun; 41(6):469-74. doi: 10.1007/bf03011539. [PMID: 8069985]
  • R J Barohn, C E Jackson, S J Rogers, L W Ridings, A L McVey. Prolonged paralysis due to nondepolarizing neuromuscular blocking agents and corticosteroids. Muscle & nerve. 1994 Jun; 17(6):647-54. doi: 10.1002/mus.880170613. [PMID: 7910951]
  • H Shiraishi, N Katsumata, T Suzuki, S Ogawa, H Suzuki. [Study of neuromuscular transmission with evoked electromyography--11. Comparison between blocks by magnesium and by pancuronium]. Masui. The Japanese journal of anesthesiology. 1994 Apr; 43(4):538-46. doi: NULL. [PMID: 8189619]
  • U L Mahisekar, C M Callan, M Derasari, A F Kirkpatrick. Infusion of large particles of thiopental sodium during anesthesia induction. Journal of clinical anesthesia. 1994 Jan; 6(1):55-8. doi: 10.1016/0952-8180(94)90120-1. [PMID: 7908208]
  • R H Henning, M C Houwertjes, A H Scaf, A den Hertog, S Agoston. Prolonged paralysis after long-term, high-dose infusion of pancuronium in anaesthetized cats. British journal of anaesthesia. 1993 Sep; 71(3):393-7. doi: 10.1093/bja/71.3.393. [PMID: 8398522]
  • Y Ohnishi, O Uchida, T Nakajima, K Kitaguchi, O Takaki, H Ohsumi, M Kuro. [Maintenance doses of vecuronium and pancuronium during hypothermic cardiopulmonary bypass]. Masui. The Japanese journal of anesthesiology. 1993 Jul; 42(7):995-1001. doi: NULL. [PMID: 8102414]
  • M Weindlamayr-Goettel, H Gilley, E Sipos, K Steinbereithner. Lipid solubility of pancuronium and vecuronium determined by n-octanol/water partitioning. British journal of anaesthesia. 1993 May; 70(5):579-80. doi: 10.1093/bja/70.5.579. [PMID: 8100440]
  • W J Fawcett, N J Fauvel, S A Feldman. Comparison of recovery index of rocuronium or vecuronium with simultaneously administered pancuronium in the isolated forearm. Anaesthesia. 1993 Mar; 48(3):200-1. doi: 10.1111/j.1365-2044.1993.tb06900.x. [PMID: 8096371]
  • P Clavelou, V Tubert, O Mansoor, C Darcha, D Guélon. [Rhabdomyolysis in severe acute asthma]. Annales francaises d'anesthesie et de reanimation. 1993; 12(3):326-8. doi: 10.1016/s0750-7658(05)80661-6. [PMID: 8250371]
  • S A Feldman, N J Fauvel, J R Hood. Recovery from pancuronium and vecuronium administered simultaneously in the isolated forearm and the effect on recovery following administration after cross-over of drugs. Anesthesia and analgesia. 1993 Jan; 76(1):92-5. doi: 10.1213/00000539-199301000-00016. [PMID: 8093426]
  • J Akeson, K Messeter, I Rosén, S Björkman. Cerebral haemodynamic and electrocortical CO2 reactivity in pigs anaesthetized with fentanyl, nitrous oxide and pancuronium. Acta anaesthesiologica Scandinavica. 1993 Jan; 37(1):85-91. doi: 10.1111/j.1399-6576.1993.tb03605.x. [PMID: 8424303]
  • C J Smith, A E Edwards, D E Gower, B J Ferguson, C P Williams. Leucocyte migration: effects of in vitro exposure to anaesthetic agents: possible potentiation of effects by adrenaline. European journal of anaesthesiology. 1992 Nov; 9(6):463-72. doi: NULL. [PMID: 1425614]
  • M S Asuero, L Larrodera, N Molins, M Rubial, P Dávila. [Plasma histamine levels after the administration of atracurium or pancuronium in patients undergoing general anesthesia]. Revista espanola de anestesiologia y reanimacion. 1992 Nov; 39(6):341-4. doi: NULL. [PMID: 1284093]
  • K Fotherby. Clinical experience and pharmacological effects of an oral contraceptive containing 20 micrograms oestrogen. Contraception. 1992 Nov; 46(5):477-88. doi: 10.1016/0010-7824(92)90151-i. [PMID: 1458894]
  • M W Quinn, F Otoo, J A Rushforth, H G Dean, J W Puntis, J Wild, M I Levene. Effect of morphine and pancuronium on the stress response in ventilated preterm infants. Early human development. 1992 Oct; 30(3):241-8. doi: 10.1016/0378-3782(92)90073-p. [PMID: 1468386]
  • M Yashiki, T Miyazaki, Y Iwasaki, T Taniguchi, T Kojima. [A case of suicide by an intravenous injection of pancuronium]. Nihon hoigaku zasshi = The Japanese journal of legal medicine. 1992 Aug; 46(4):282-5. doi: NULL. [PMID: 1405022]
  • M Fujinaga, J M Baden, R I Mazze. Developmental toxicity of nondepolarizing muscle relaxants in cultured rat embryos. Anesthesiology. 1992 Jun; 76(6):999-1003. doi: 10.1097/00000542-199206000-00021. [PMID: 1350890]
  • S Song, J K Chen, P J Yang, M L He, L M Li, B C Fan, H Rekers, K Fotherby. A cross-over study of three oral contraceptives containing ethinyloestradiol and either desogestrel or levonorgestrel. Contraception. 1992 Jun; 45(6):523-32. doi: 10.1016/0010-7824(92)90103-z. [PMID: 1535580]
  • P S Buckner, D A Todd, K Lui, E John. Effect of short-term muscle relaxation on neonatal plasma volume. Critical care medicine. 1991 Nov; 19(11):1357-61. doi: 10.1097/00003246-199111000-00009. [PMID: 1935153]
  • B Chraemmer-Jørgensen, P F Høilund-Carlsen, J Marving, J Strøm, M D Nielsen, B H Jensen, H Lønborg-Jensen, K Schmidt. Left-ventricular performance, volumes, and catecholamine responses during anaesthesia induction--monitoring by combined radionuclide cardiography and right heart catheterization. European journal of anaesthesiology. 1991 Nov; 8(6):437-43. doi: NULL. [PMID: 1765041]
  • F A Wali, V Makinde, A Mahoney, H F Seeley. Effects of pancuronium and vecuronium on plasma levels of lactate dehydrogenase and creatine kinase in patients undergoing gynaecological surgery. Biochemical Society transactions. 1991 Nov; 19(4):423S. doi: 10.1042/bst019423s. [PMID: 1686597]
  • D Ostergaard, J Viby-Mogensen, H K Hanel, L T Skovgaard. Pretreatment with pancuronium before suxamethonium administration in patients heterozygous for the usual and the atypical plasma cholinesterase gene. Acta anaesthesiologica Scandinavica. 1991 Aug; 35(6):502-7. doi: 10.1111/j.1399-6576.1991.tb03337.x. [PMID: 1897345]
  • F A Wali, V Makinde. Effects of pancuronium and vecuronium on creatine kinase in rat isolated heart, liver, kidney and diaphragm. Biochemical Society transactions. 1991 Aug; 19(3):336S. doi: 10.1042/bst019336s. [PMID: 1686003]
  • C W Hogue, J Martyn, T R Baker, P Vouros. Recovery of pancuronium from peritoneal dialysate in a severely burned child. Anesthesia and analgesia. 1991 Jul; 73(1):83-6. doi: 10.1213/00000539-199107000-00015. [PMID: 1858994]
  • M Kawate. [The effect of sodium nitroprusside (SNP)-induced hypotension on the sympatho-adrenal nerve activity]. Masui. The Japanese journal of anesthesiology. 1991 Feb; 40(2):258-74. doi: NULL. [PMID: 2020101]
  • F A Wali, V Makinde. Effects of pancuronium and vecuronium on creatine phosphokinase in rat isolated heart, liver, kidney and diaphragm. General pharmacology. 1991; 22(2):301-4. doi: 10.1016/0306-3623(91)90453-d. [PMID: 1676006]
  • F A Wali, V Makinde. Comparative effects of vecuronium and pancuronium on release of lactate dehydrogenase in rat isolated diaphragm, liver, kidney and heart. Acta physiologica Hungarica. 1991; 78(2):127-33. doi: NULL. [PMID: 1687303]
  • G E Larijani, I Gratz, M Silverberg, A G Jacobi. Clinical pharmacology of the neuromuscular blocking agents. DICP : the annals of pharmacotherapy. 1991 Jan; 25(1):54-64. doi: 10.1177/106002809102500111. [PMID: 1672571]
  • F A Wali, V Makinde, A Mahoney, H F Seeley. Effects of pancuronium and vecuronium on plasma levels of immunoglobulins, IgG, IgM and IgE, in patients undergoing minor gynaecological surgery. Acta anaesthesiologica Belgica. 1991; 42(2):107-12. doi: . [PMID: 1681665]
  • S Oshita, S Denda, Y Fujiwara, H Takeshita, F Kosaka. Pretreatment with d-tubocurarine, vecuronium, and pancuronium attenuates succinylcholine-induced increases in plasma norepinephrine concentrations in humans. Anesthesia and analgesia. 1991 Jan; 72(1):84-8. doi: 10.1213/00000539-199101000-00015. [PMID: 1670598]
  • J M Wierda, P J van der Starre, A H Scaf, W D Kloppenburg, J H Proost, S Agoston. Pharmacokinetics of pancuronium in patients undergoing coronary artery surgery with and without low dose dopamine. Clinical pharmacokinetics. 1990 Dec; 19(6):491-8. doi: 10.2165/00003088-199019060-00005. [PMID: 2292170]
  • E J Briglia, P L Davis, M Katz, L A Dal Cortivo. Attempted murder with pancuronium. Journal of forensic sciences. 1990 Nov; 35(6):1468-76. doi: NULL. [PMID: 2262781]
  • S Djurica, M Cirović, B Lukić, G Gregorić, D Tasovac-Ponomarev. Some extrathyroid regulatory mechanisms' aspects in thyroid humoral state at the delivery. Materia medica Polona. Polish journal of medicine and pharmacy. 1990 Jul; 22(3):198-201. doi: NULL. [PMID: 2132426]
  • C Yajima, N Sugai, K Hanaoka, K Numata, K Yamamoto, Y Kushida, S Murakami, H Yamamura. [Comparative pharmacokinetics of pipecuronium bromide, pancuronium bromide and vecuronium bromide in anesthetized man]. Masui. The Japanese journal of anesthesiology. 1990 Jul; 39(7):882-9. doi: NULL. [PMID: 1976829]
  • P Tomá, G Lucigrai, P Dodero, M Lituania. Prenatal detection of an abdominal mass by MR imaging performed while the fetus is immobilized with pancuronium bromide. AJR. American journal of roentgenology. 1990 May; 154(5):1049-50. doi: 10.2214/ajr.154.5.2157328. [PMID: 2157328]
  • L Popović, E Kunec-Vajić. [Inhibition of plasma cholinesterase by pancuronium and vecuronium]. Lijecnicki vjesnik. 1990 May; 112(5-6):142-3. doi: NULL. [PMID: 1978211]
  • J M Wierda, G F Karliczek, R H Vandenbrom, I Pinto, U W Kersten-Kleef, D K Meijer, S Agoston. Pharmacokinetics and cardiovascular dynamics of pipecuronium bromide during coronary artery surgery. Canadian journal of anaesthesia = Journal canadien d'anesthesie. 1990 Mar; 37(2):183-91. doi: 10.1007/bf03005467. [PMID: 2155718]
  • J Futo, J P Kupferberg, J Moss. Inhibition of histamine N-methyltransferase (HNMT) in vitro by neuromuscular relaxants. Biochemical pharmacology. 1990 Feb; 39(3):415-20. doi: 10.1016/0006-2952(90)90045-m. [PMID: 1968337]
  • T R Baker, P Vouros, D Rindgen, J A Martyn. Mass spectrometric assay for determination of pancuronium and vecuronium in biological fluids utilizing the moving belt introduction system. Biomedical & environmental mass spectrometry. 1990 Feb; 19(2):69-74. doi: 10.1002/bms.1200190204. [PMID: 1968351]
  • D Solomon, L Bunegin, M Albin. The effect of magnesium sulfate administration on cerebral and cardiac toxicity of bupivacaine in dogs. Anesthesiology. 1990 Feb; 72(2):341-6. doi: 10.1097/00000542-199002000-00021. [PMID: 2301766]
  • W E Mol, D K Meijer. Hepatic transport mechanisms for bivalent organic cations. Subcellular distribution and hepato-biliary concentration gradients of some steroidal muscle relaxants. Biochemical pharmacology. 1990 Jan; 39(2):383-90. doi: 10.1016/0006-2952(90)90038-m. [PMID: 1967941]
  • J Freeman, S M Lesko, A A Mitchell, M F Epstein, S Shapiro. Hyperbilirubinemia following exposure to pancuronium bromide in newborns. Developmental pharmacology and therapeutics. 1990; 14(4):209-15. doi: 10.1159/000480900. [PMID: 2397674]
  • A Wada, M Arita, H Takara, K Sumikawa, Y Uezono, F Izumi. Inhibition by vecuronium of carbachol-induced influx of 22Na+, 45Ca2+ and secretion of catecholamines in cultured bovine adrenal medullary cells. Naunyn-Schmiedeberg's archives of pharmacology. 1989 Dec; 340(6):605-9. doi: 10.1007/bf00717734. [PMID: 2575709]
  • K J Choudhury, O S Mosuro, D J Ffoulkes-Crabbe. Effect of suxamethonium, pancuronium, neostigmine and halothane on serum cholinesterase activity. Middle East journal of anaesthesiology. 1989 Oct; 10(3):315-21. doi: . [PMID: 2637954]
  • M Adt, P Schmucker, J H Baumert, H J Reimann. Cardiovascular reaction and plasma histamine concentration after application of atracurium and pancuronium with and without previous prophylaxis with H1- and H2-receptor antagonists. Journal of cardiothoracic anesthesia. 1989 Oct; 3(5 Suppl 1):23. doi: 10.1016/0888-6296(89)90766-7. [PMID: 2485222]
  • L Berntman, B Rosberg, I Shweikh, H Yousef. Atracurium and pancuronium in renal insufficiency. Acta anaesthesiologica Scandinavica. 1989 Jan; 33(1):48-52. doi: 10.1111/j.1399-6576.1989.tb02858.x. [PMID: 2644748]
  • R H Vandenbrom, J M Wierda. Pancuronium bromide in the intensive care unit: a case of overdose. Anesthesiology. 1988 Dec; 69(6):996-7. doi: 10.1097/00000542-198812000-00040. [PMID: 3195777]
  • J E Caldwell, K P Castagnoli, P C Canfell, M R Fahey, D P Lynam, D M Fisher, R D Miller. Pipecuronium and pancuronium: comparison of pharmacokinetics and duration of action. British journal of anaesthesia. 1988 Dec; 61(6):693-7. doi: 10.1093/bja/61.6.693. [PMID: 2849968]
  • S J Basta, J J Savarese, H H Ali, P B Embree, A F Schwartz, G D Rudd, W B Wastila. Clinical pharmacology of doxacurium chloride. A new long-acting nondepolarizing muscle relaxant. Anesthesiology. 1988 Oct; 69(4):478-86. doi: 10.1097/00000542-198810000-00006. [PMID: 2972233]
  • H Hashemzadeh-Gargari, A J Baertschi, P G Guyenet. Baroreceptor-independent medullary mechanism for release of vasopressin during hypotension in rats. The Journal of endocrinology. 1988 Jul; 118(1):101-11. doi: 10.1677/joe.0.1180101. [PMID: 2842427]
  • R Schiavello, A Mezza, L Feo, M Sciarra, C Monaco. Compartmental analysis of lidocaine kinetics during extracorporeal circulation. Journal of cardiothoracic anesthesia. 1988 Jun; 2(3):290-6. doi: 10.1016/0888-6296(88)90307-9. [PMID: 17171862]
  • T Furuta, P C Canfell, K P Castagnoli, M L Sharma, R D Miller. Quantitation of pancuronium, 3-desacetylpancuronium, vecuronium, 3-desacetylvecuronium, pipecuronium and 3-desacetylpipecuronium in biological fluids by capillary gas chromatography using nitrogen-sensitive detection. Journal of chromatography. 1988 May; 427(1):41-53. doi: 10.1016/0378-4347(88)80103-8. [PMID: 2900840]
  • E Crosby, J A Robblee. Cyclosporine-pancuronium interaction in a patient with a renal allograft. Canadian journal of anaesthesia = Journal canadien d'anesthesie. 1988 May; 35(3 ( Pt 1)):300-2. doi: 10.1007/bf03010635. [PMID: 3289771]