Lysophosphatidylglycerol (BioDeep_00000857571)
代谢物信息卡片
Lysophosphatidylglycerol
化学式: C22H44O9P- (483.2723)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCCCCCCCCCCCCCC(=O)OCC(COP(=O)([O-])OCC(CO)O)O
InChI: InChI=1S/C22H45O9P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-22(26)29-17-21(25)19-31-32(27,28)30-18-20(24)16-23/h20-21,23-25H,2-19H2,1H3,(H,27,28)/p-1/t20-,21-/m0/s1
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
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Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Chitra Subramanian, Matthew W Frank, My-Kyung Yun, Charles O Rock. The Phospholipase A1 Activity of Glycerol Ester Hydrolase (Geh) Is Responsible for Extracellular 2-12(S)-Methyltetradecanoyl-Lysophosphatidylglycerol Production in Staphylococcus aureus.
mSphere.
2023 Mar; ?(?):e0003123. doi:
10.1128/msphere.00031-23. [PMID: 36976028] - Jannik Nedergaard Pedersen, Zhiping Jiang, Gunna Christiansen, Jennifer C Lee, Jan Skov Pedersen, Daniel E Otzen. Lysophospholipids induce fibrillation of the repeat domain of Pmel17 through intermediate core-shell structures.
Biochimica et biophysica acta. Proteins and proteomics.
2019 05; 1867(5):519-528. doi:
10.1016/j.bbapap.2018.11.007. [PMID: 30471451] - Ying Zhang, Jing-Dian Zhang, Ming-Qin Zhu, Ming Zhang, Yan-Jun Xu, Li Cui, Naranjan S Dhalla. Effect of lysophosphatidylglycerol on intracellular free Ca2+ concentration in A10 vascular smooth muscle cells.
Canadian journal of physiology and pharmacology.
2017 Oct; 95(10):1283-1288. doi:
10.1139/cjpp-2017-0127. [PMID: 28727921] - Shigenobu Emoto, Makoto Kurano, Kuniyuki Kano, Keisuke Matsusaki, Hiroharu Yamashita, Masako Nishikawa, Koji Igarashi, Hitoshi Ikeda, Junken Aoki, Joji Kitayama, Yutaka Yatomi. Analysis of glycero-lysophospholipids in gastric cancerous ascites.
Journal of lipid research.
2017 04; 58(4):763-771. doi:
10.1194/jlr.p072090. [PMID: 28143894] - Makoto Kurano, Kuniyuki Kano, Tomotaka Dohi, Hirotaka Matsumoto, Koji Igarashi, Masako Nishikawa, Ryunosuke Ohkawa, Hitoshi Ikeda, Katsumi Miyauchi, Hiroyuki Daida, Junken Aoki, Yutaka Yatomi. Different origins of lysophospholipid mediators between coronary and peripheral arteries in acute coronary syndrome.
Journal of lipid research.
2017 02; 58(2):433-442. doi:
10.1194/jlr.p071803. [PMID: 28007846] - Toshihiko Tsutsumi, Yoko Okamoto, Syougo Yamakawa, Cheng Bingjun, Akira Ishihara, Tamotsu Tanaka, Akira Tokumura. Reduced rat plasma lysophosphatidylglycerol or lysophosphatidic acid level as a biomarker of aristolochic acid-induced renal and adipose dysfunctions.
Life sciences.
2016 Jul; 157(?):208-216. doi:
10.1016/j.lfs.2016.06.003. [PMID: 27267499] - Jun Zhang, Dan Xu, Jia Nie, Ruili Han, Yonggong Zhai, Yuguang Shi. Comparative gene identification-58 (CGI-58) promotes autophagy as a putative lysophosphatidylglycerol acyltransferase.
The Journal of biological chemistry.
2014 Nov; 289(47):33044-53. doi:
10.1074/jbc.m114.573857. [PMID: 25315780] - Byron L Sparkes, Emily E Archer Slone, Mary Roth, Ruth Welti, Sherry D Fleming. Intestinal lipid alterations occur prior to antibody-induced prostaglandin E2 production in a mouse model of ischemia/reperfusion.
Biochimica et biophysica acta.
2010 Apr; 1801(4):517-25. doi:
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10.1016/j.bbalip.2009.10.009. [PMID: 19857602] - Jae Woong Shim, Seong Ho Jo, Sang Doo Kim, Ha Young Lee, Jeanho Yun, Yoe Sik Bae. Lysophosphatidylglycerol inhibits formyl peptide receptorlike-1-stimulated chemotactic migration and IL-1beta production from human phagocytes.
Experimental & molecular medicine.
2009 Aug; 41(8):584-91. doi:
10.3858/emm.2009.41.8.064. [PMID: 19381066] - Peter J Meikle, Stephen Duplock, David Blacklock, Phillip D Whitfield, Gemma Macintosh, John J Hopwood, Maria Fuller. Effect of lysosomal storage on bis(monoacylglycero)phosphate.
The Biochemical journal.
2008 Apr; 411(1):71-8. doi:
10.1042/bj20071043. [PMID: 18052935] - Marcia Riesselman, Heini M Miettinen, Jeannie M Gripentrog, Connie I Lord, Brendan Mumey, Edward A Dratz, Jamal Stie, Ross M Taylor, Algirdas J Jesaitis. C-terminal tail phosphorylation of N-formyl peptide receptor: differential recognition of two neutrophil chemoattractant receptors by monoclonal antibodies NFPR1 and NFPR2.
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2007 Aug; 179(4):2520-31. doi:
10.4049/jimmunol.179.4.2520. [PMID: 17675514] - Su Duy Nguyen, Dai-Eun Sok. Preferential inhibition of paraoxonase activity of human paraoxonase 1 by negatively charged lipids.
Journal of lipid research.
2004 Dec; 45(12):2211-20. doi:
10.1194/jlr.m400144-jlr200. [PMID: 15375178] - Norikazu Ichihashi, Kenji Kurokawa, Miki Matsuo, Chikara Kaito, Kazuhisa Sekimizu. Inhibitory effects of basic or neutral phospholipid on acidic phospholipid-mediated dissociation of adenine nucleotide bound to DnaA protein, the initiator of chromosomal DNA replication.
The Journal of biological chemistry.
2003 Aug; 278(31):28778-86. doi:
10.1074/jbc.m212202200. [PMID: 12767975] - N Sanghera, T J Pinheiro. Unfolding and refolding of cytochrome c driven by the interaction with lipid micelles.
Protein science : a publication of the Protein Society.
2000 Jun; 9(6):1194-202. doi:
10.1110/ps.9.6.1194. [PMID: 10892811] - Y H Kim, J S Choi, J S Yoo, Y M Park, M S Kim. Structural identification of glycerolipid molecular species isolated from cyanobacterium Synechocystis sp. PCC 6803 using fast atom bombardment tandem mass spectrometry.
Analytical biochemistry.
1999 Feb; 267(2):260-70. doi:
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Protein science : a publication of the Protein Society.
1999 Feb; 8(2):381-93. doi:
10.1110/ps.8.2.381. [PMID: 10048331] - P Huang, Q Liu, G A Scarborough. Lysophosphatidylglycerol: a novel effective detergent for solubilizing and purifying the cystic fibrosis transmembrane conductance regulator.
Analytical biochemistry.
1998 May; 259(1):89-97. doi:
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1998 Jan; 6(1):1-10. doi:
10.1016/s0928-0987(97)00057-2. [PMID: 16256702] - J N Keller, M R Steiner, F W Holtsberg, M P Mattson, S M Steiner. Lysophosphatidic acid-induced proliferation-related signals in astrocytes.
Journal of neurochemistry.
1997 Sep; 69(3):1073-84. doi:
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