Stanate (BioDeep_00000855788)
代谢物信息卡片
Stanate
化学式: C34H36Cl2N4O4Sn (754.1135466)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCC1=C(C2=NC1=CC3=C(C(=C([N-]3)C=C4C(=C(C(=CC5=NC(=C2)C(=C5C)CC)[N-]4)C)CCC(=O)O)CCC(=O)O)C)C.[Cl-].[Cl-].[Sn+4]
InChI: /q
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Huan Xu, Qing Wen, Xiuduan Xu, Zhihui Liu, Shasha Liu, Hongli Wang, Chongchong Zhang, Delian Wan, Kun Liu, Lina Du, Chao Yuan, Lun Song. Induction of heme oxygenase-1 antagonizes PM2.5-induced pulmonary VEGFA expression through regulating HIF-1α.
Journal of biochemical and molecular toxicology.
2023 Aug; ?(?):e23494. doi:
10.1002/jbt.23494. [PMID: 37563788] - Claudia Kusmic, Cristina Barsanti, Marco Matteucci, Nicoletta Vesentini, Gualtiero Pelosi, Nader G Abraham, Antonio L'Abbate. Up-regulation of heme oxygenase-1 after infarct initiation reduces mortality, infarct size and left ventricular remodeling: experimental evidence and proof of concept.
Journal of translational medicine.
2014 Apr; 12(?):89. doi:
10.1186/1479-5876-12-89. [PMID: 24708733] - Luca Vanella, Komal Sodhi, Dong Hyun Kim, Nitin Puri, Mani Maheshwari, Terry D Hinds, Lars Bellner, Dov Goldstein, Stephen J Peterson, Joseph I Shapiro, Nader G Abraham. Increased heme-oxygenase 1 expression in mesenchymal stem cell-derived adipocytes decreases differentiation and lipid accumulation via upregulation of the canonical Wnt signaling cascade.
Stem cell research & therapy.
2013 Mar; 4(2):28. doi:
10.1186/scrt176. [PMID: 23497794] - M J Maisels, H Yang. Tin-mesoporphyrin in the treatment of refractory hyperbilirubinemia due to Rh incompatibility.
Journal of perinatology : official journal of the California Perinatal Association.
2012 Nov; 32(11):899-900. doi:
10.1038/jp.2012.45. [PMID: 23128060] - Angela P H Burgess, Luca Vanella, Lars Bellner, Katherine Gotlinger, John R Falck, Nader G Abraham, Michal L Schwartzman, Attallah Kappas. Heme oxygenase (HO-1) rescue of adipocyte dysfunction in HO-2 deficient mice via recruitment of epoxyeicosatrienoic acids (EETs) and adiponectin.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology.
2012; 29(1-2):99-110. doi:
10.1159/000337591. [PMID: 22415079] - Giuseppina Marrazzo, Paolo Bosco, Francesco La Delia, Giovanni Scapagnini, Claudia Di Giacomo, Michele Malaguarnera, Fabio Galvano, Anna Nicolosi, Giovanni Li Volti. Neuroprotective effect of silibinin in diabetic mice.
Neuroscience letters.
2011 Oct; 504(3):252-6. doi:
10.1016/j.neulet.2011.09.041. [PMID: 21970972] - Dong Hyun Kim, Luca Vanella, Kazuyoshi Inoue, Angela Burgess, Katherine Gotlinger, Vijaya Lingam Manthati, Sreenivasulu Reddy Koduru, Darryl C Zeldin, John R Falck, Michal L Schwartzman, Nader G Abraham. Epoxyeicosatrienoic acid agonist regulates human mesenchymal stem cell-derived adipocytes through activation of HO-1-pAKT signaling and a decrease in PPARγ.
Stem cells and development.
2010 Dec; 19(12):1863-73. doi:
10.1089/scd.2010.0098. [PMID: 20412023] - Karl A Nath, Melissa C Hernandez, Anthony J Croatt, Zvonimir S Katusic, Luis A Juncos. Heme oxygenase activity as a determinant of the renal hemodynamic response to low-dose ANG II.
American journal of physiology. Regulatory, integrative and comparative physiology.
2010 Nov; 299(5):R1183-91. doi:
10.1152/ajpregu.00212.2010. [PMID: 20702802] - Dong Hyun Kim, Angela P Burgess, Ming Li, Peter L Tsenovoy, Francesco Addabbo, John A McClung, Nitin Puri, Nader G Abraham. Heme oxygenase-mediated increases in adiponectin decrease fat content and inflammatory cytokines tumor necrosis factor-alpha and interleukin-6 in Zucker rats and reduce adipogenesis in human mesenchymal stem cells.
The Journal of pharmacology and experimental therapeutics.
2008 Jun; 325(3):833-40. doi:
10.1124/jpet.107.135285. [PMID: 18334666] - Marisol Orozco-Ibarra, Omar Noel Medina-Campos, Dolores Javier Sánchez-González, Claudia María Martínez-Martínez, Esaú Floriano-Sánchez, Abel Santamaría, Victoria Ramirez, Norma A Bobadilla, José Pedraza-Chaverri. Evaluation of oxidative stress in D-serine induced nephrotoxicity.
Toxicology.
2007 Jan; 229(1-2):123-35. doi:
10.1016/j.tox.2006.10.008. [PMID: 17110013] - Manisha Tiwari, Ramesh Chandra, Sujata K Das, Satya Prakash. Tin mesoporphyrin in conjunction with retinoic acid reverses the retinoic acid induced enhancement of phospholipase A(2) activity in vivo in rats.
Artificial cells, blood substitutes, and immobilization biotechnology.
2007; 35(3):275-85. doi:
10.1080/10731190701378600. [PMID: 17573627] - Tomoko Kawakami, Toru Takahashi, Hiroko Shimizu, Kiichi Nakahira, Mamoru Takeuchi, Hiroshi Katayama, Masataka Yokoyama, Kiyoshi Morita, Reiko Akagi, Shigeru Sassa. Highly liver-specific heme oxygenase-1 induction by interleukin-11 prevents carbon tetrachloride-induced hepatotoxicity.
International journal of molecular medicine.
2006 Oct; 18(4):537-46. doi:
10.3892/ijmm.18.4.537. [PMID: 16964402] - Maria Antonietta Di Noia, Sarah Van Driesche, Ferdinando Palmieri, Li-Ming Yang, Shuo Quan, Alvin I Goodman, Nader G Abraham. Heme oxygenase-1 enhances renal mitochondrial transport carriers and cytochrome C oxidase activity in experimental diabetes.
The Journal of biological chemistry.
2006 Jun; 281(23):15687-93. doi:
10.1074/jbc.m510595200. [PMID: 16595661] - Alvin I Goodman, Praveen N Chander, Rita Rezzani, Michal L Schwartzman, Raymond F Regan, Luigi Rodella, Saadet Turkseven, Elias A Lianos, Phyllis A Dennery, Nader G Abraham. Heme oxygenase-2 deficiency contributes to diabetes-mediated increase in superoxide anion and renal dysfunction.
Journal of the American Society of Nephrology : JASN.
2006 Apr; 17(4):1073-81. doi:
10.1681/asn.2004121082. [PMID: 16524951] - Fady T Botros, Michal L Schwartzman, Charles T Stier, Alvin I Goodman, Nader G Abraham. Increase in heme oxygenase-1 levels ameliorates renovascular hypertension.
Kidney international.
2005 Dec; 68(6):2745-55. doi:
10.1111/j.1523-1755.2005.00745.x. [PMID: 16316349] - Saadet Turkseven, Adam Kruger, Christopher J Mingone, Pawel Kaminski, Muneo Inaba, Luigi F Rodella, Susumu Ikehara, Michael S Wolin, Nader G Abraham. Antioxidant mechanism of heme oxygenase-1 involves an increase in superoxide dismutase and catalase in experimental diabetes.
American journal of physiology. Heart and circulatory physiology.
2005 Aug; 289(2):H701-7. doi:
10.1152/ajpheart.00024.2005. [PMID: 15821039] - Zuanel Diaz, Michael I Assaraf, Wilson H Miller, Hyman M Schipper. Astroglial cytoprotection by erythropoietin pre-conditioning: implications for ischemic and degenerative CNS disorders.
Journal of neurochemistry.
2005 Apr; 93(2):392-402. doi:
10.1111/j.1471-4159.2005.03038.x. [PMID: 15816862] - Rita Rezzani, Luigi Rodella, Barbara Buffoli, Alvin A Goodman, Nader G Abraham, Elias A Lianos, Rossella Bianchi. Change in renal heme oxygenase expression in cyclosporine A-induced injury.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.
2005 Jan; 53(1):105-12. doi:
10.1177/002215540505300112. [PMID: 15637343] - Shou Quan, Pawel M Kaminski, Liming Yang, Toshisuke Morita, Muneo Inaba, Susumu Ikehara, Alvin I Goodman, Michael S Wolin, Nader G Abraham. Heme oxygenase-1 prevents superoxide anion-associated endothelial cell sloughing in diabetic rats.
Biochemical and biophysical research communications.
2004 Mar; 315(2):509-16. doi:
10.1016/j.bbrc.2004.01.086. [PMID: 14766238] - Francisca Rodriguez, Rowena Kemp, Michael Balazy, Alberto Nasjletti. Effects of exogenous heme on renal function: role of heme oxygenase and cyclooxygenase.
Hypertension (Dallas, Tex. : 1979).
2003 Oct; 42(4):680-4. doi:
10.1161/01.hyp.0000085785.40581.1a. [PMID: 12900432] - Kiichi Nakahira, Toru Takahashi, Hiroko Shimizu, Kyoichiro Maeshima, Kenji Uehara, Hiromi Fujii, Hideki Nakatsuka, Masataka Yokoyama, Reiko Akagi, Kiyoshi Morita. Protective role of heme oxygenase-1 induction in carbon tetrachloride-induced hepatotoxicity.
Biochemical pharmacology.
2003 Sep; 66(6):1091-105. doi:
10.1016/s0006-2952(03)00444-1. [PMID: 12963497] - Abas H Laftah, Kishor Raja, Robert J Simpson, Timothy J Peters. Effect of Tin-mesoporphyrin, an inhibitor of haem catabolism, on intestinal iron absorption.
British journal of haematology.
2003 Jul; 122(2):298-304. doi:
10.1046/j.1365-2141.2003.04376.x. [PMID: 12846900] - Marek Nalos, Damian Vassilev, Antje Pittner, Pierre Asfar, Uwe Bernd Brückner, Elisabeth Marion Schneider, Michael Georgieff, Peter Radermacher, Gebhard Froeba. Tin-mesoporphyrin for inhibition of heme oxygenase during long-term hyperdynamic porcine endotoxemia.
Shock (Augusta, Ga.).
2003 Jun; 19(6):526-32. doi:
10.1097/01.shk.0000070732.34700.07. [PMID: 12785007] - A Kappas, G S Drummond, D P Munson, J R Marshall. Sn-Mesoporphyrin interdiction of severe hyperbilirubinemia in Jehovah's Witness newborns as an alternative to exchange transfusion.
Pediatrics.
2001 Dec; 108(6):1374-7. doi:
10.1542/peds.108.6.1374. [PMID: 11731664] - H Shimizu, T Takahashi, T Suzuki, A Yamasaki, T Fujiwara, Y Odaka, M Hirakawa, H Fujita, R Akagi. Protective effect of heme oxygenase induction in ischemic acute renal failure.
Critical care medicine.
2000 Mar; 28(3):809-17. doi:
10.1097/00003246-200003000-00033. [PMID: 10752834] - L Berglund, R A Galbraith, L Emtestam, G S Drummond, B Angelin, A Kappas. Heme oxygenase inhibitors transiently increase serum ferritin concentrations without altering other acute-phase reactants in man.
Pharmacology.
1999 Jul; 59(1):51-6. doi:
10.1159/000028305. [PMID: 10352426] - D M Suttner, K Sridhar, C S Lee, T Tomura, T N Hansen, P A Dennery. Protective effects of transient HO-1 overexpression on susceptibility to oxygen toxicity in lung cells.
The American journal of physiology.
1999 03; 276(3):L443-51. doi:
10.1152/ajplung.1999.276.3.l443. [PMID: 10070108] - J C Martinez, H O Garcia, L E Otheguy, G S Drummond, A Kappas. Control of severe hyperbilirubinemia in full-term newborns with the inhibitor of bilirubin production Sn-mesoporphyrin.
Pediatrics.
1999 Jan; 103(1):1-5. doi:
10.1542/peds.103.1.1. [PMID: 9917431] - T Valaes, G S Drummond, A Kappas. Control of hyperbilirubinemia in glucose-6-phosphate dehydrogenase-deficient newborns using an inhibitor of bilirubin production, Sn-mesoporphyrin.
Pediatrics.
1998 May; 101(5):E1. doi:
10.1542/peds.101.5.e1. [PMID: 9565434] - G S Drummond, A Kappas. Sn-mesoporphyrin suppression of hyperbilirubinemia in EHBR/Eis rats, an animal model of Dubin-Johnson syndrome.
Pharmacology.
1998 Mar; 56(3):158-64. doi:
10.1159/000028194. [PMID: 9532616] - P A Dennery, K J Sridhar, C S Lee, H E Wong, V Shokoohi, P A Rodgers, D R Spitz. Heme oxygenase-mediated resistance to oxygen toxicity in hamster fibroblasts.
The Journal of biological chemistry.
1997 Jun; 272(23):14937-42. doi:
10.1074/jbc.272.23.14937. [PMID: 9169465] - A Kappas, G S Drummond, C Henschke, T Valaes. Direct comparison of Sn-mesoporphyrin, an inhibitor of bilirubin production, and phototherapy in controlling hyperbilirubinemia in term and near-term newborns.
Pediatrics.
1995 Apr; 95(4):468-74. doi:
NULL. [PMID: 7700742] - T Valaes, S Petmezaki, C Henschke, G S Drummond, A Kappas. Control of jaundice in preterm newborns by an inhibitor of bilirubin production: studies with tin-mesoporphyrin.
Pediatrics.
1994 Jan; 93(1):1-11. doi:
NULL. [PMID: 8265301] - A Kappas, G S Drummond, R A Galbraith. Prolonged clinical use of a heme oxygenase inhibitor: hematological evidence for an inducible but reversible iron-deficiency state.
Pediatrics.
1993 Mar; 91(3):537-9. doi:
NULL. [PMID: 8441555] - R A Galbraith, G S Drummond, A Kappas. Suppression of bilirubin production in the Crigler-Najjar type I syndrome: studies with the heme oxygenase inhibitor tin-mesoporphyrin.
Pediatrics.
1992 Feb; 89(2):175-82. doi:
NULL. [PMID: 1734381] - N L Greenbaum, A Kappas. Comparative photoactivity of tin and zinc porphyrin inhibitors of heme oxygenase: pronounced photolability of the zinc compounds.
Photochemistry and photobiology.
1991 Aug; 54(2):183-92. doi:
10.1111/j.1751-1097.1991.tb02005.x. [PMID: 1780355] - R A Galbraith, A Kappas. Pharmacokinetics of tin-mesoporphyrin in man and the effects of tin-chelated porphyrins on hyperexcretion of heme pathway precursors in patients with acute inducible porphyria.
Hepatology (Baltimore, Md.).
1989 Jun; 9(6):882-8. doi:
10.1002/hep.1840090616. [PMID: 2714739] - J K Delaney, D Mauzerall, G S Drummond, A Kappas. Photophysical properties of Sn-porphyrins: potential clinical implications.
Pediatrics.
1988 Apr; 81(4):498-504. doi:
NULL. [PMID: 3353183]