Angiotensinamide (BioDeep_00000855671)

   


代谢物信息卡片


(Asn1,Val5)-Angiotensin II

化学式: C49H70N14O11 (1030.534823)
中文名称: 血管紧张素胺
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(C)C(C(=O)NC(CC1=CC=C(C=C1)O)C(=O)NC(C(C)C)C(=O)NC(CC2=CN=CN2)C(=O)N3CCCC3C(=O)NC(CC4=CC=CC=C4)C(=O)O)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC(=O)N)N
InChI: InChI=1S/C49H70N14O11/c1-26(2)39(61-42(67)33(12-8-18-55-49(52)53)57-41(66)32(50)23-38(51)65)45(70)58-34(20-29-14-16-31(64)17-15-29)43(68)62-40(27(3)4)46(71)59-35(22-30-24-54-25-56-30)47(72)63-19-9-13-37(63)44(69)60-36(48(73)74)21-28-10-6-5-7-11-28/h5-7,10-11,14-17,24-27,32-37,39-40,64H,8-9,12-13,18-23,50H2,1-4H3,(H2,51,65)(H,54,56)(H,57,66)(H,58,70)(H,59,71)(H,60,69)(H,61,67)(H,62,68)(H,73,74)(H4,52,53,55)/t32-,33-,34-,35-,36-,37-,39-,40-/m0/s1

描述信息

C - Cardiovascular system > C01 - Cardiac therapy > C01C - Cardiac stimulants excl. cardiac glycosides
D002317 - Cardiovascular Agents > D014662 - Vasoconstrictor Agents
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone

同义名列表

2 个代谢物同义名

(Asn1,Val5)-Angiotensin II; Angiotensinamide



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Guanjie Chen, Daniel Shriner, Ayo P Doumatey, Jie Zhou, Amy R Bentley, Lin Lei, Adebowale Adeyemo, Charles N Rotimi. Refining genome-wide associated loci for serum uric acid in individuals with African ancestry. Human molecular genetics. 2020 02; 29(3):506-514. doi: 10.1093/hmg/ddz272. [PMID: 31841133]
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  • Tarah Fatani, Asma Binjab, Hope Weiler, Atul Sharma, Celia Rodd. Persistent elevation of fibroblast growth factor 23 concentrations in healthy appropriate-for-gestational-age preterm infants. Journal of pediatric endocrinology & metabolism : JPEM. 2015 Jul; 28(7-8):825-32. doi: 10.1515/jpem-2014-0186. [PMID: 25968436]
  • Andrew D Blann, Gregory Y H Lip. Renal, endothelial function, warfarin management, and the CHADS2, CHA2DS2VASc and HAS-BLED scores inpredicting MACE in AF. Thrombosis and haemostasis. 2015 May; 113(5):1155-7. doi: 10.1160/th14-11-0932. [PMID: 25716989]
  • Shur-Jen Wang, Stanley J F Laulederkind, G Thomas Hayman, Victoria Petri, Weisong Liu, Jennifer R Smith, Rajni Nigam, Melinda R Dwinell, Mary Shimoyama. PhenoMiner: a quantitative phenotype database for the laboratory rat, Rattus norvegicus. Application in hypertension and renal disease. Database : the journal of biological databases and curation. 2015; 2015(?):. doi: 10.1093/database/bau128. [PMID: 25632109]
  • Samira Fargali, Angelo L Garcia, Masato Sadahiro, Cheng Jiang, William G Janssen, Wei-Jye Lin, Valeria Cogliani, Alice Elste, Steven Mortillo, Cheryl Cero, Britta Veitenheimer, Gallia Graiani, Giulio M Pasinetti, Sushil K Mahata, John W Osborn, George W Huntley, Greg R Phillips, Deanna L Benson, Alessandro Bartolomucci, Stephen R Salton. The granin VGF promotes genesis of secretory vesicles, and regulates circulating catecholamine levels and blood pressure. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2014 May; 28(5):2120-33. doi: 10.1096/fj.13-239509. [PMID: 24497580]
  • I Heuch, I Heuch, K Hagen, J A Zwart. Does high blood pressure reduce the risk of chronic low back pain? The Nord-Trøndelag Health Study. European journal of pain (London, England). 2014 Apr; 18(4):590-8. doi: 10.1002/j.1532-2149.2013.00398.x. [PMID: 24019262]
  • Patrick Lacolley, Véronique Regnault, Antonino Nicoletti, Zhenlin Li, Jean-Baptiste Michel. The vascular smooth muscle cell in arterial pathology: a cell that can take on multiple roles. Cardiovascular research. 2012 Jul; 95(2):194-204. doi: 10.1093/cvr/cvs135. [PMID: 22467316]
  • Laura A Bienvenu, James Morgan, Amanda J Rickard, Greg H Tesch, Greg A Cranston, Elizabeth K Fletcher, Lea M D Delbridge, Morag J Young. Macrophage mineralocorticoid receptor signaling plays a key role in aldosterone-independent cardiac fibrosis. Endocrinology. 2012 Jul; 153(7):3416-25. doi: 10.1210/en.2011-2098. [PMID: 22653557]
  • H-Y Ou, H-T Wu, Y-C Yang, J-S Wu, J-T Cheng, C-J Chang. Elevated retinol binding protein 4 contributes to insulin resistance in spontaneously hypertensive rats. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. 2011 May; 43(5):312-8. doi: 10.1055/s-0031-1271746. [PMID: 21365528]
  • Zhiqian Tong, Jinling Zhang, Wenhong Luo, Weishan Wang, Fangxu Li, Hui Li, Hongjun Luo, Jing Lu, Jiangning Zhou, You Wan, Rongqiao He. Urine formaldehyde level is inversely correlated to mini mental state examination scores in senile dementia. Neurobiology of aging. 2011 Jan; 32(1):31-41. doi: 10.1016/j.neurobiolaging.2009.07.013. [PMID: 19879019]
  • Awantika Deshmukh, Karen M Rodrigue, Kristen M Kennedy, Susan Land, Bradley S Jacobs, Naftali Raz. Synergistic effects of the MTHFR C677T polymorphism and hypertension on spatial navigation. Biological psychology. 2009 Feb; 80(2):240-5. doi: 10.1016/j.biopsycho.2008.10.003. [PMID: 19013496]
  • Ettore Guidi, Mariagrazia Cozzi, Silvano Milani, Elena Spada. Nephrectomy modifies renal angiotensin II effects in kidney donors. American journal of hypertension. 2008 May; 21(5):592-8. doi: 10.1038/ajh.2008.35. [PMID: 18437153]
  • M Dharmani, M R Mustafa, F I Achike, M K Sim. Effect of des-aspartate-angiotensin I on the actions of angiotensin II in the isolated renal and mesenteric vasculature of hypertensive and STZ-induced diabetic rats. Regulatory peptides. 2005 Jul; 129(1-3):213-9. doi: 10.1016/j.regpep.2005.02.007. [PMID: 15927718]
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  • J R Blair-West, J P Coghlan, D A Denton, D T Fei, K J Hardy, B A Scoggins, R D Wright. A dose-response comparison of the actions of angiotensin II and angiotensin III in sheep. The Journal of endocrinology. 1980 Dec; 87(3):409-17. doi: 10.1677/joe.0.0870409. [PMID: 7452126]
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  • F A Mendelsohn. Different potencies of [Asp1, Ile5]- and [Asn1, Val5]-angiotensin II in stimulating aldosterone production from rat adrenal zona glomerulosa cells in vitro. Clinical and experimental pharmacology & physiology. 1980 Mar; 7(2):199-203. doi: 10.1111/j.1440-1681.1980.tb00061.x. [PMID: 7379348]
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