eticlopride (BioDeep_00000855626)
代谢物信息卡片
eticlopride
化学式: C17H25ClN2O3 (340.15536099999997)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCC1=CC(=C(C(=C1O)C(=O)NCC2CCCN2CC)OC)Cl
InChI: InChI=1S/C17H25ClN2O3/c1-4-11-9-13(18)16(23-3)14(15(11)21)17(22)19-10-12-7-6-8-20(12)5-2/h9,12,21H,4-8,10H2,1-3H3,(H,19,22)/t12-/m0/s1
描述信息
D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents > D018492 - Dopamine Antagonists
C78272 - Agent Affecting Nervous System > C66883 - Dopamine Antagonist
同义名列表
1 个代谢物同义名
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Xuemei Liu, Tao Fan, Jinshuai Guan, Ai Luo, Yan Yu, Daohong Chen, Bing Mao, Hongli Jiang, Wei Liu. Dopamine relieves inflammatory responses through the D2 receptor after electroacupuncture at ST36 in a mouse model of chronic obstructive pulmonary disease.
Acupuncture in medicine : journal of the British Medical Acupuncture Society.
2022 Jul; ?(?):9645284221107684. doi:
10.1177/09645284221107684. [PMID: 35775581] - Panpan Wang, Ting Cao, Jiaojiao Chen, Yiguo Jiang, Cheng Wang, John L Waddington, Xuechu Zhen. D2 receptor-mediated miRNA-143 expression is associated with the effects of antipsychotic drugs on phencyclidine-induced schizophrenia-related locomotor hyperactivity and with Neuregulin-1 expression in mice.
Neuropharmacology.
2019 10; 157(?):107675. doi:
10.1016/j.neuropharm.2019.107675. [PMID: 31233824] - Pradeep Paudel, Su Hui Seong, Hyun Ah Jung, Jae Sue Choi. Characterizing fucoxanthin as a selective dopamine D3/D4 receptor agonist: Relevance to Parkinson's disease.
Chemico-biological interactions.
2019 Sep; 310(?):108757. doi:
10.1016/j.cbi.2019.108757. [PMID: 31323226] - Jianjing Cao, Rachel D Slack, Oluyomi M Bakare, Caitlin Burzynski, Rana Rais, Barbara S Slusher, Theresa Kopajtic, Alessandro Bonifazi, Michael P Ellenberger, Hideaki Yano, Yi He, Guo-Hua Bi, Zheng-Xiong Xi, Claus J Loland, Amy Hauck Newman. Novel and High Affinity 2-[(Diphenylmethyl)sulfinyl]acetamide (Modafinil) Analogues as Atypical Dopamine Transporter Inhibitors.
Journal of medicinal chemistry.
2016 12; 59(23):10676-10691. doi:
10.1021/acs.jmedchem.6b01373. [PMID: 27933960] - Andrew B Norman, Mantana K Norman, Michael R Tabet, Vladimir L Tsibulsky, Amadeo J Pesce. Competitive dopamine receptor antagonists increase the equiactive cocaine concentration during self-administration.
Synapse (New York, N.Y.).
2011 May; 65(5):404-11. doi:
10.1002/syn.20858. [PMID: 20812328] - Gregory C Hadlock, Pei-Wen Chu, Elliot T Walters, Glen R Hanson, Annette E Fleckenstein. Methamphetamine-induced dopamine transporter complex formation and dopaminergic deficits: the role of D2 receptor activation.
The Journal of pharmacology and experimental therapeutics.
2010 Oct; 335(1):207-12. doi:
10.1124/jpet.110.166660. [PMID: 20622144] - Gregory C Hadlock, Anthony J Baucum, Jill L King, Kristen A Horner, Glen A Cook, James W Gibb, Diana G Wilkins, Glen R Hanson, Annette E Fleckenstein. Mechanisms underlying methamphetamine-induced dopamine transporter complex formation.
The Journal of pharmacology and experimental therapeutics.
2009 Apr; 329(1):169-74. doi:
10.1124/jpet.108.145631. [PMID: 19141713] - Olaf Prante, Rainer Tietze, Carsten Hocke, Stefan Löber, Harald Hübner, Torsten Kuwert, Peter Gmeiner. Synthesis, radiofluorination, and in vitro evaluation of pyrazolo[1,5-a]pyridine-based dopamine D4 receptor ligands: discovery of an inverse agonist radioligand for PET.
Journal of medicinal chemistry.
2008 Mar; 51(6):1800-10. doi:
10.1021/jm701375u. [PMID: 18307287] - Emanuela Izzo, Pietro Paolo Sanna, George F Koob. Impairment of dopaminergic system function after chronic treatment with corticotropin-releasing factor.
Pharmacology, biochemistry, and behavior.
2005 Aug; 81(4):701-8. doi:
10.1016/j.pbb.2005.04.017. [PMID: 16005056] - Den'etsu Sutoo, Kayo Akiyama. Music improves dopaminergic neurotransmission: demonstration based on the effect of music on blood pressure regulation.
Brain research.
2004 Aug; 1016(2):255-62. doi:
10.1016/j.brainres.2004.05.018. [PMID: 15246862] - Judith Varady, Xihan Wu, Xueliang Fang, Ji Min, Zengjian Hu, Beth Levant, Shaomeng Wang. Molecular modeling of the three-dimensional structure of dopamine 3 (D3) subtype receptor: discovery of novel and potent D3 ligands through a hybrid pharmacophore- and structure-based database searching approach.
Journal of medicinal chemistry.
2003 Oct; 46(21):4377-92. doi:
10.1021/jm030085p. [PMID: 14521403] - X Xu, J T Stewart. Chiral analysis of selected dopamine receptor antagonists in serum using capillary electrophoresis with cyclodextrin additives.
Journal of pharmaceutical and biomedical analysis.
2000 Sep; 23(4):735-43. doi:
10.1016/s0731-7085(00)00356-3. [PMID: 10975249] - J Arita, A Hashi, K Hoshi, S Mazawa, S Suzuki. D2 dopamine-receptor-mediated inhibition of proliferation of rat lactotropes in culture is accompanied by changes in cell shape.
Neuroendocrinology.
1998 Sep; 68(3):163-71. doi:
10.1159/000054362. [PMID: 9734000] - O M Youngren, G R Pitts, R E Phillips, M E el Halawani. Dopaminergic control of prolactin secretion in the turkey.
General and comparative endocrinology.
1996 Nov; 104(2):225-30. doi:
10.1006/gcen.1996.0165. [PMID: 8930613] - J A Kiritsy-Roy, J B Halter, S M Gordon, M J Smith, L C Terry. Role of the central nervous system in hemodynamic and sympathoadrenal responses to cocaine in rats.
The Journal of pharmacology and experimental therapeutics.
1990 Oct; 255(1):154-60. doi:
NULL. [PMID: 2213551]