N5-iminoethyl-L-ornithine (BioDeep_00000855600)
代谢物信息卡片
N5-iminoethyl-L-ornithine
化学式: C7H15N3O2 (173.1164)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(=NCCCC(C(=O)O)N)N
InChI: InChI=1S/C7H15N3O2/c1-5(8)10-4-2-3-6(9)7(11)12/h6H,2-4,9H2,1H3,(H2,8,10)(H,11,12)/t6-/m0/s1
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
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Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
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0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Giovane S Galdino, Carlos H Xavier, Renato Almeida, Grazielle Silva, Marcos A Fontes, Gustavo Menezes, Igor D Duarte, Andrea C Perez. The Nitric oxide/CGMP/KATP pathway mediates systemic and central antinociception induced by resistance exercise in rats.
The International journal of neuroscience.
2015; 125(10):765-73. doi:
10.3109/00207454.2014.970256. [PMID: 25271801] - Jamila H Siamwala, Paul M Dias, Syamantak Majumder, Manoj K Joshi, Vilas P Sinkar, Gautam Banerjee, Suvro Chatterjee. L-theanine promotes nitric oxide production in endothelial cells through eNOS phosphorylation.
The Journal of nutritional biochemistry.
2013 Mar; 24(3):595-605. doi:
10.1016/j.jnutbio.2012.02.016. [PMID: 22819553] - A Rus, M A Peinado, S Blanco, M L Del Moral. Is endothelial-nitric-oxide-synthase-derived nitric oxide involved in cardiac hypoxia/reoxygenation-related damage?.
Journal of biosciences.
2011 Mar; 36(1):69-78. doi:
10.1007/s12038-011-9006-4. [PMID: 21451249] - Alma Rus, Francisco Molina, Ma Angeles Peinado, Ma Luisa del Moral. Endothelial NOS-derived nitric oxide prevents injury resulting from reoxygenation in the hypoxic lung.
Free radical research.
2010 Sep; 44(9):1027-35. doi:
10.3109/10715762.2010.498479. [PMID: 20815765] - Mahmoud M El-Mas, Ming Fan, Abdel A Abdel-Rahman. Facilitation of myocardial PI3K/Akt/nNOS signaling contributes to ethanol-evoked hypotension in female rats.
Alcoholism, clinical and experimental research.
2009 Jul; 33(7):1158-68. doi:
10.1111/j.1530-0277.2009.00939.x. [PMID: 19389198] - Graciela Ostera, Fuyuki Tokumasu, Fabiano Oliveira, Juliana Sa, Tetsuya Furuya, Clarissa Teixeira, James Dvorak. Plasmodium falciparum: food vacuole localization of nitric oxide-derived species in intraerythrocytic stages of the malaria parasite.
Experimental parasitology.
2008 Sep; 120(1):29-38. doi:
10.1016/j.exppara.2008.04.014. [PMID: 18504040] - P A Cowled, A Khanna, P E Laws, J B F Field, R A Fitridge. Simvastatin plus nitric oxide synthase inhibition modulates remote organ damage following skeletal muscle ischemia-reperfusion injury.
Journal of investigative surgery : the official journal of the Academy of Surgical Research.
2008 May; 21(3):119-26. doi:
10.1080/08941930802046501. [PMID: 18569431] - Muge Yemisci, Hakan Ay, Cetin Kocaefe, Jianhua Qui, Kamil Topalkara, Meral Ozgüç, Serafettin Kirazli, Osman Ozcebe, Michael A Moskowitz, Turgay Dalkara. Statin potentiates human platelet eNOS activity without enhancing eNOS mRNA and protein levels.
Cerebrovascular diseases (Basel, Switzerland).
2008; 26(2):190-8. doi:
10.1159/000145327. [PMID: 18628618] - Shen-Kou Tsai, Li-Man Hung, Yuan-Tsung Fu, Henrich Cheng, Mao-Wei Nien, Hsin-Yi Liu, Friedrich Bo-Yuan Zhang, Shiang-Suo Huang. Resveratrol neuroprotective effects during focal cerebral ischemia injury via nitric oxide mechanism in rats.
Journal of vascular surgery.
2007 Aug; 46(2):346-53. doi:
10.1016/j.jvs.2007.04.044. [PMID: 17600658] - Bahjat Al-Ani, Peter W Hewett, Suborna Ahmed, Melissa Cudmore, Takeshi Fujisawa, Shakil Ahmad, Asif Ahmed. The release of nitric oxide from S-nitrosothiols promotes angiogenesis.
PloS one.
2006 Dec; 1(?):e25. doi:
10.1371/journal.pone.0000025. [PMID: 17183652] - Jose Luis Viñas, Anna Sola, Meritxell Genescà, Vicente Alfaro, Felip Pí, Georgina Hotter. NO and NOS isoforms in the development of apoptosis in renal ischemia/reperfusion.
Free radical biology & medicine.
2006 Mar; 40(6):992-1003. doi:
10.1016/j.freeradbiomed.2005.10.046. [PMID: 16540395] - Jason M Hoover, Alan D Kaye, Ikhlass N Ibrahim, Aaron M Fields, Todd A Richards. Analysis of responses to kava kava in the feline pulmonary vascular bed.
Journal of medicinal food.
2006; 9(1):62-71. doi:
10.1089/jmf.2006.9.62. [PMID: 16579730] - Jason M Hoover, Alan D Kaye, Ikhlass N Ibrahim, Aaron M Fields, Todd A Richards. Analysis of responses to St. John's Wort in the feline pulmonary vascular bed.
Journal of herbal pharmacotherapy.
2004; 4(3):47-62. doi:
. [PMID: 15829469] - I Gourdon, M C Guérin, J Torreilles, P Roch. Nitric oxide generation by hemocytes of the mussel Mytilus galloprovincialis.
Nitric oxide : biology and chemistry.
2001 Feb; 5(1):1-6. doi:
10.1006/niox.2000.0327. [PMID: 11178931] - J Ródenas, T Carbonell, M T Mitjavila. Different roles for nitrogen monoxide and peroxynitrite in lipid peroxidation induced by activated neutrophils.
Free radical biology & medicine.
2000 Feb; 28(3):374-80. doi:
10.1016/s0891-5849(99)00250-6. [PMID: 10699748] - E Moilanen, L L Thomsen, D W Miles, D W Happerfield, R G Knowles, S Moncada. Persistent induction of nitric oxide synthase in tumours from mice treated with the anti-tumour agent 5,6-dimethylxanthenone-4-acetic acid.
British journal of cancer.
1998; 77(3):426-33. doi:
10.1038/bjc.1998.68. [PMID: 9472639] - S S Greenberg, J R Lancaster, J Xie, T G Sarphie, X Zhao, L Hua, T Freeman, D R Kapusta, T D Giles, D R Powers. Effects of NO synthase inhibitors, arginine-deficient diet, and amiloride in pregnant rats.
The American journal of physiology.
1997 Sep; 273(3 Pt 2):R1031-45. doi:
10.1152/ajpregu.1997.273.3.r1031. [PMID: 9321883] - B J DeWitt, H C Champion, J R Marrone, D B McNamara, T D Giles, S S Greenberg, P J Kadowitz. Differential effects of L-N5-(1-iminoethyl)-ornithine on tone and endothelium-dependent vasodilator responses.
The American journal of physiology.
1997 Sep; 273(3 Pt 1):L588-94. doi:
10.1152/ajplung.1997.273.3.l588. [PMID: 9316493] - M A Wheeler, S D Smith, G García-Cardeña, C F Nathan, R M Weiss, W C Sessa. Bacterial infection induces nitric oxide synthase in human neutrophils.
The Journal of clinical investigation.
1997 Jan; 99(1):110-6. doi:
10.1172/jci119121. [PMID: 9011564] - J C Salerno, K McMillan, B S Masters. Binding of intermediate, product, and substrate analogs to neuronal nitric oxide synthase: ferriheme is sensitive to ligand-specific effects in the L-arginine binding site.
Biochemistry.
1996 Sep; 35(36):11839-45. doi:
10.1021/bi953015w. [PMID: 8794766] - M Lu, W H Wang. Nitric oxide regulates the low-conductance K+ channel in basolateral membrane of cortical collecting duct.
The American journal of physiology.
1996 May; 270(5 Pt 1):C1336-42. doi:
10.1152/ajpcell.1996.270.5.c1336. [PMID: 8967433] - J Ródenas, M T Mitjavila, T Carbonell. Simultaneous generation of nitric oxide and superoxide by inflammatory cells in rats.
Free radical biology & medicine.
1995 May; 18(5):869-75. doi:
10.1016/0891-5849(94)00215-6. [PMID: 7797094] - S S Greenberg, J Xie, J J Spitzer, J F Wang, J Lancaster, M B Grisham, D R Powers, T D Giles. Nitro containing L-arginine analogs interfere with assays for nitrate and nitrite.
Life sciences.
1995; 57(21):1949-61. doi:
10.1016/0024-3205(95)02181-h. [PMID: 7475944]
