trans-Platin (BioDeep_00000855481)
代谢物信息卡片
trans-Platin
化学式: Cl2H6N2Pt+2 (298.9556)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: N.N.Cl[Pt+2]Cl
InChI: /q
描述信息
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D003432 - Cross-Linking Reagents
D011838 - Radiation-Sensitizing Agents
D000970 - Antineoplastic Agents
同义名列表
1 个代谢物同义名
数据库引用编号
5 个数据库交叉引用编号
- ChEBI: CHEBI:27899
- ChEBI: CHEBI:35852
- PubChem: 441203
- DrugBank: DB00515
- MeSH: Cisplatin
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
|---|
文献列表
- Jiong Li, Xiangjun Ma, Faying Xu, Yuanliang Yan, Weiqing Chen. Babaodan overcomes cisplatin resistance in cholangiocarcinoma via inhibiting YAP1.
Pharmaceutical biology.
2024 Dec; 62(1):314-325. doi:
10.1080/13880209.2024.2331060. [PMID: 38571483] - Ruixue Tian, Shuqin Tang, Jingyu Zhao, Yajie Hao, Limei Zhao, Xiutao Han, Xingru Wang, Lijun Zhang, Rongshan Li, Xiaoshuang Zhou. β-Hydroxybutyrate Protects Against Cisplatin-Induced Renal Damage via Regulating Ferroptosis.
Renal failure.
2024 Dec; 46(1):2354918. doi:
10.1080/0886022x.2024.2354918. [PMID: 38757723] - Fei Ma, Qun Wang, Di Zhang, Zihong Wang, Hui Xie, Xianghong Liu, Hongxing Zhang, Haiyan Song, Shiguang Sun. Comparative efficacy and safety of Chinese medicine injections as an adjunctive therapy for cervical cancer in Chinese patients: a network meta-analysis.
Pharmaceutical biology.
2024 Dec; 62(1):170-182. doi:
10.1080/13880209.2024.2312217. [PMID: 38334090] - Satoko Nakayama, Emiko Yoda, Saki Yamashita, Yuka Takamatsu, Yasutomo Suzuki, Yukihiro Kondo, Shuntaro Hara. Knockdown of iPLA2γ enhances cisplatin-induced apoptosis by increasing ROS-dependent peroxidation of mitochondrial phospholipids in bladder cancer cells.
Free radical biology & medicine.
2024 Aug; 220(?):301-311. doi:
10.1016/j.freeradbiomed.2024.05.016. [PMID: 38734266] - Heba A S El-Nashar, Mahmood A Al-Azzawi, Hassan Hadi Al-Kazzaz, Yasemin Khudiar Alghanimi, Shaden Mohamed Kocaebli, Moaz Alhmammi, Ahmed Asad, Tarek Salam, Mohamed El-Shazly, Mohamed A M Ali. HPLC-ESI/MS-MS metabolic profiling of white pitaya fruit and cytotoxic potential against cervical cancer: Comparative studies, synergistic effects, and molecular mechanistic approaches.
Journal of pharmaceutical and biomedical analysis.
2024 Jul; 244(?):116121. doi:
10.1016/j.jpba.2024.116121. [PMID: 38581932] - Yuexiao Tang, Tao Yao, Xin Tian, Xintong Xia, Xingxiao Huang, Zhewen Qin, Zhong Shen, Lin Zhao, Yaping Zhao, Bowen Diao, Yan Ping, Xiaoxiao Zheng, Yonghao Xu, Hui Chen, Tao Qian, Tao Ma, Ben Zhou, Suowen Xu, Qimin Zhou, Yong Liu, Mengle Shao, Wei Chen, Bo Shan, Ying Wu. Hepatic IRE1α-XBP1 signaling promotes GDF15-mediated anorexia and body weight loss in chemotherapy.
The Journal of experimental medicine.
2024 Jul; 221(7):. doi:
10.1084/jem.20231395. [PMID: 38695876] - Shuli Man, Yingfang Cui, Dandan Shi, Panpan Lv, Long Ma, Wenyuan Gao. Formosanin C inhibits pulmonary metastasis by targeting stearyl CoA desaturase-1.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2024 Jul; 129(?):155689. doi:
10.1016/j.phymed.2024.155689. [PMID: 38728921] - Jianan Guo, Yifei Le, Aini Yuan, Jing Liu, Hang Chen, Jiannan Qiu, Cui Wang, Xiaobing Dou, Xingyu Yuan, Dezhao Lu. Astragaloside IV ameliorates cisplatin-induced liver injury by modulating ferroptosis-dependent pathways.
Journal of ethnopharmacology.
2024 Jun; 328(?):118080. doi:
10.1016/j.jep.2024.118080. [PMID: 38521426] - Congwen Wang, Mingxing Zhang, Jing Peng, Meng Zhang, Chong Lu, Xingling Qi, Qingyan Luo, Yumeng Wang, Guiling Li. Combining cisplatin with Pinellia pedatisecta Schott lipid-soluble extract induces tumor immunogenic cell death in cervical cancer.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2024 Jun; 128(?):155504. doi:
10.1016/j.phymed.2024.155504. [PMID: 38452404] - Jia Jian, Li Yu-Qing, Han Rang-Yue, Zhong Xia, Xie Ke-Huan, Yan Ying, Wang Li, Tan Rui-Zhi. Isorhamnetin ameliorates cisplatin-induced acute kidney injury in mice by activating SLPI-mediated anti-inflammatory effect in macrophage.
Immunopharmacology and immunotoxicology.
2024 Jun; 46(3):319-329. doi:
10.1080/08923973.2024.2329621. [PMID: 38466121] - Zhongyu Qin, Jin Ma, Xu Chu, Taozhen Guo, Pengcheng Feng, Ming Wang. Delivery of miR-29a improves the permeability of cisplatin by downregulating collagen I expression.
Biochemical and biophysical research communications.
2024 May; 710(?):149884. doi:
10.1016/j.bbrc.2024.149884. [PMID: 38598901] - Yanwen Zhuang, Yu Ouyang, Li Ding, Miaowen Xu, Fanfeng Shi, Dan Shan, Dawei Cao, Xiaowei Cao. Source Tracing of Kidney Injury via the Multispectral Fingerprint Identified by Machine Learning-Driven Surface-Enhanced Raman Spectroscopic Analysis.
ACS sensors.
2024 May; 9(5):2622-2633. doi:
10.1021/acssensors.4c00407. [PMID: 38700898] - Xinlin Lin, Mengsi Zheng, Kai Xiong, Fa Wang, Yu Chen, Liangnian Ji, Hui Chao. Two-Photon Photodegradation of E3 Ubiquitin Ligase Cereblon by a Ru(II) Complex: Inducing Ferroptosis in Cisplatin-Resistant Tumor Cells.
Journal of medicinal chemistry.
2024 May; 67(10):8372-8382. doi:
10.1021/acs.jmedchem.4c00545. [PMID: 38745549] - Divya Bisht, Deena Prakash, Ramesh Kumar, Arvind Kumar Shakya, Sadhana Shrivastava. Phytochemical profiling and nephroprotective potential of ethanolic leaf extract of Polyalthia longifolia against cisplatin-induced oxidative stress in rat model.
Journal of ethnopharmacology.
2024 May; 326(?):117922. doi:
10.1016/j.jep.2024.117922. [PMID: 38403004] - Ziyi Liu, Hanbing Zhang, Guodong Hong, Xiuli Bi, Jun Hu, Tiancheng Zhang, Yachun An, Na Guo, Fengyue Dong, Yu Xiao, Wen Li, Xiaoxu Zhao, Bo Chu, Siwei Guo, Xiaohan Zhang, Renjie Chai, Xiaolong Fu. Inhibition of Gpx4-mediated ferroptosis alleviates cisplatin-induced hearing loss in C57BL/6 mice.
Molecular therapy : the journal of the American Society of Gene Therapy.
2024 May; 32(5):1387-1406. doi:
10.1016/j.ymthe.2024.02.029. [PMID: 38414247] - Jun Sang, Chen-Kai Liu, Jue Liu, Guan-Cong Luo, Wei-Ji Zheng, Ya Bai, De-Yun Jiang, Jiang-Ni Pu, Su An, Tian-Rui Xu. Jolkinolide B synergistically potentiates the antitumor activity of GPX4 inhibitors via inhibiting TrxR1 in cisplatin-resistant bladder cancer cells.
Biochemical pharmacology.
2024 May; 223(?):116194. doi:
10.1016/j.bcp.2024.116194. [PMID: 38583812] - Xiaoju Ding, Yunjie Jin, Xiaokai Shi, Yidi Wang, Zhibo Jin, Lei Yin, Shenglin Gao, Yibo Lei, Jinjian Yang. TDO2 promotes bladder cancer progression via AhR-mediated SPARC/FILIP1L signaling.
Biochemical pharmacology.
2024 May; 223(?):116172. doi:
10.1016/j.bcp.2024.116172. [PMID: 38552852] - Manik Chandra Shill, Heba A S El-Nashar, Patricia Prova Mollick, Rabindra Nath Acharyya, Silvia Afrin, Hemayet Hossain, Shimul Halder, Muhammad Torequl Islam, Md Shimul Bhuia, Hasan Mahmud Reza, Mohamed El-Shazly, Mohammad S Mubarak. Longevity Spinach (Gynura procumbens) Ameliorated Oxidative Stress and Inflammatory Mediators in Cisplatin-Induced Organ Dysfunction in Rats: Comprehensive in vivo and in silico Studies.
Chemistry & biodiversity.
2024 May; 21(5):e202301719. doi:
10.1002/cbdv.202301719. [PMID: 38361048] - Tatiana J Carneiro, Ana L M Batista de Carvalho, Martin Vojtek, Raquel C Laginha, Maria Paula M Marques, Carmen Diniz, Ana M Gil. Pd2Spermine as an Alternative Therapeutics for Cisplatin-Resistant Triple-Negative Breast Cancer.
Journal of medicinal chemistry.
2024 Apr; 67(8):6839-6853. doi:
10.1021/acs.jmedchem.4c00435. [PMID: 38590144] - Viktoriia Cherkasova, Yaroslav Ilnytskyy, Olga Kovalchuk, Igor Kovalchuk. Targeting Colorectal Cancer: Unravelling the Transcriptomic Impact of Cisplatin and High-THC Cannabis Extract.
International journal of molecular sciences.
2024 Apr; 25(8):. doi:
10.3390/ijms25084439. [PMID: 38674023] - Lizhi Zhou, Zebin Deng, Yilong Wang, Hao Zhang, Shu Yan, Yashpal S Kanwar, Yinhuai Wang, Yingbo Dai, Fei Deng. PRMT4 interacts with NCOA4 to inhibit ferritinophagy in cisplatin-induced acute kidney injury.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
2024 Apr; 38(7):e23584. doi:
10.1096/fj.202302596r. [PMID: 38568836] - Haohui Lin, Manhon Chung, Jingchun Sun, Yi Yang, Li Zhang, Xiaohua Pan, Minghui Wei, Sa Cai, Yu Pan. Ganoderma spore lipid ameliorates docetaxel, cisplatin, and 5-fluorouracil chemotherapy-induced damage to bone marrow mesenchymal stem cells and hematopoiesis.
BMC complementary medicine and therapies.
2024 Apr; 24(1):158. doi:
10.1186/s12906-024-04445-x. [PMID: 38610025] - Mingyang Sun, He Chang, Fangyang Jiang, Wenjing Zhang, Qingxuan Yang, Xinhe Wang, Guangfu Lv, He Lin, Haoming Luo, Zhe Lin, Yuchen Wang. Hazel Leaf Polyphenol Extract Alleviated Cisplatin-Induced Acute Kidney Injury by Reducing Ferroptosis through Inhibiting Hippo Signaling.
Molecules (Basel, Switzerland).
2024 Apr; 29(8):. doi:
10.3390/molecules29081729. [PMID: 38675549] - Xiaomin Shen, Yue Peng, Haixia Zhou, Xiaoxia Ye, Zhong Han, Xiangchao Shi. A Pt(II) complex bearing N-heterocycle ring induced ferroptotic cell death in ovarian cancer.
Journal of inorganic biochemistry.
2024 04; 253(?):112502. doi:
10.1016/j.jinorgbio.2024.112502. [PMID: 38335582] - Li Zhang, Wenao Song, Hua Li, Xiaolin Cui, Jingyu Ma, Rongrong Wang, Yue Xu, Ming Li, Xiaohui Bai, Dawei Wang, Haihui Sun, Zhiming Lu. 4-octyl itaconate alleviates cisplatin-induced ferroptosis possibly via activating the NRF2/HO-1 signalling pathway.
Journal of cellular and molecular medicine.
2024 Apr; 28(7):e18207. doi:
10.1111/jcmm.18207. [PMID: 38506087] - Fangfang Cai, Dangran Li, Kaiqian Zhou, Wen Zhang, Yunwen Yang. Tiliroside attenuates acute kidney injury by inhibiting ferroptosis through the disruption of NRF2-KEAP1 interaction.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2024 Apr; 126(?):155407. doi:
10.1016/j.phymed.2024.155407. [PMID: 38340577] - Meiping Xie, Cheng Wang, Yuxia Sun, Qiuyuan Mao, Shasha Sun, Mianhua Wu, Jiapeng Zhu, Wenting Li, Zequn Jiang. Maimendong and Qianjinweijing Tang combined with cisplatin suppressed lung cancer through targeting lncRNA-p21.
Journal of ethnopharmacology.
2024 Mar; 322(?):117547. doi:
10.1016/j.jep.2023.117547. [PMID: 38135231] - Khaidem Devika Chanu, Soibam Thoithoisana, Amit Kar, Pulok Kumar Mukherjee, P Radhakrishnanand, Keyur Parmar, Nanaocha Sharma. Phytochemically analysed extract of Ageratina adenophora (Sprengel) R.M.King & H. Rob. initiates caspase 3-dependant apoptosis in colorectal cancer cell: A synergistic approach with chemotherapeutic drugs.
Journal of ethnopharmacology.
2024 Mar; 322(?):117591. doi:
10.1016/j.jep.2023.117591. [PMID: 38104872] - Mengxin Hu, Jie Li, Yunwei Fu, Enshuang Xu, Ding Li, Siqi Huang, Danning Tong, Shengzi Jin, Tongxu Guan, Yun Liu. Establishment and characterization of cisplatin-resistant cell lines from canine mammary gland tumors.
Theriogenology.
2024 Mar; 217(?):103-112. doi:
10.1016/j.theriogenology.2024.01.017. [PMID: 38271764] - Ran Du, Ji-Shi Liu, Hao Huang, Yu-Xing Liu, Jie-Yuan Jin, Chen-Yu Wang, Yi Dong, Liang-Liang Fan, Rong Xiang. RTN3 deficiency exacerbates cisplatin-induced acute kidney injury through the disruption of mitochondrial stability.
Mitochondrion.
2024 Mar; 75(?):101851. doi:
10.1016/j.mito.2024.101851. [PMID: 38336146] - Yan Luo, Jiaxing Zhang, Yue Jiao, Hao Huang, Liangshan Ming, Yunlei Song, Yanlong Niu, Xiaolu Tang, Liwei Liu, Yi Li, Yumao Jiang. Dihydroartemisinin abolishes cisplatin-induced nephrotoxicity in vivo.
Journal of natural medicines.
2024 Mar; 78(2):439-454. doi:
10.1007/s11418-024-01783-5. [PMID: 38351420] - Fei Li, Henghui Zhang, Yuan Huang, Dongqing Li, Zaosong Zheng, Kunfeng Xie, Chun Cao, Qiong Wang, Xinlei Zhao, Zehai Huang, Shijun Chen, Haiyong Chen, Qin Fan, Fan Deng, Lina Hou, Xiaolin Deng, Wanlong Tan. Single-cell transcriptome analysis reveals the association between histone lactylation and cisplatin resistance in bladder cancer.
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.
2024 Mar; 73(?):101059. doi:
10.1016/j.drup.2024.101059. [PMID: 38295753] - Mohsen Karami Fath, Kamyar Nasiri, Shabnam Ghasemzadeh, Seyedeh Tabasom Nejati, Nima Ghafari, Sahand Saeidpour Masouleh, Esmaeel Dadgar, Kimia Sadat Kazemi, Mahla Esfahaniani. Thymoquinone potentiates anti-cancer effects of cisplatin in oral squamous cell carcinoma via targeting oxidative stress.
Chemical biology & drug design.
2024 03; 103(3):e14492. doi:
10.1111/cbdd.14492. [PMID: 38485457] - Zhongtang Li, Riming He, Jiahui Liu, Xiaoming Jin, Beibei Jiang, Yunlan Lao, Shudong Yang. JianPiYiShen formula prevents cisplatin-induced acute kidney injury in mice by improving necroptosis through MAPK pathway.
BMC complementary medicine and therapies.
2024 Feb; 24(1):101. doi:
10.1186/s12906-024-04366-9. [PMID: 38402163] - Yukiko Nishiguch, Rina Fujiwara-Tani, Shota Nukaga, Ryoichi Nishida, Ayaka Ikemoto, Rika Sasaki, Shiori Mori, Ruiko Ogata, Shingo Kishi, Yudai Hojo, Hisashi Shinohara, Masayuki Sho, Hiroki Kuniyasu. Pterostilbene Induces Apoptosis from Endoplasmic Reticulum Stress Synergistically with Anticancer Drugs That Deposit Iron in Mitochondria.
International journal of molecular sciences.
2024 Feb; 25(5):. doi:
10.3390/ijms25052611. [PMID: 38473857] - Jiaping Chen, Rong Zhao, Yangwei Wang, Han Xiao, Wei Lin, Mingxin Diao, Shiwen He, Peiyuan Mei, Yongde Liao. G protein-coupled estrogen receptor activates PI3K/AKT/mTOR signaling to suppress ferroptosis via SREBP1/SCD1-mediated lipogenesis.
Molecular medicine (Cambridge, Mass.).
2024 Feb; 30(1):28. doi:
10.1186/s10020-023-00763-x. [PMID: 38383297] - Lingkun Wang, Yaochen Xie, Boneng Xiao, Xuelin He, Guanghui Ying, Huiyan Zha, Chen Yang, Xuejin Jin, Guilin Li, Li Ping, Jincheng Wang, Qinjie Weng. Isorhamnetin alleviates cisplatin-induced acute kidney injury via enhancing fatty acid oxidation.
Free radical biology & medicine.
2024 Feb; 212(?):22-33. doi:
10.1016/j.freeradbiomed.2023.12.010. [PMID: 38101584] - Xiang Song, Xinzhao Wang, Xiqi Chen, Zhiyong Yu, Yongkun Zhou. SRSF1 inhibits ferroptosis and reduces cisplatin chemosensitivity of triple-negative breast cancer cells through the circSEPT9/GCH1 axis.
Journal of proteomics.
2024 02; 292(?):105055. doi:
10.1016/j.jprot.2023.105055. [PMID: 38040194] - Fan-E Cheng, Zheng Li, Xing Bai, Yanyan Jing, Junfei Zhang, Xiaoqian Shi, Tingting Li, Weiqiang Li. Investigation on the mechanism of the combination of eremias multiocellata and cisplatin in reducing chemoresistance of gastric cancer based on in vitro and in vivo experiments.
Aging.
2024 Feb; 16(4):3386-3403. doi:
10.18632/aging.205540. [PMID: 38345573] - Min Jeong Kim, Young Suk Kim, Seo Rin Kim, Dong Won Lee, Soo Bong Lee, Il Young Kim. Pre-treatment with β-hydroxybutyrate mitigates cisplatin-induced acute kidney injury.
Biochemical and biophysical research communications.
2024 Feb; 695(?):149482. doi:
10.1016/j.bbrc.2024.149482. [PMID: 38211529] - Wei Bo, Ning Yu, Xiaokai Wang, Chun Wang, Chunying Liu. Lactate promoted cisplatin resistance in NSCLC by modulating the m6A modification-mediated FOXO3/MAGI1-IT1/miR-664b-3p/IL-6R axis.
Neoplasia (New York, N.Y.).
2024 Feb; 48(?):100960. doi:
10.1016/j.neo.2023.100960. [PMID: 38184887] - Somayeh Hashemi Sheikhshabani, Paratoo Modarres, Soudeh Ghafouri-Fard, Zeinab Amini-Farsani, Lavin Khodaee, Nasibeh Shaygan, Zahra Amini-Farsani, Mir Davood Omrani. Meta-analysis of microarray data to determine gene indicators involved in cisplatin resistance in non-small cell lung cancer.
Cancer reports (Hoboken, N.J.).
2024 02; 7(2):e1970. doi:
10.1002/cnr2.1970. [PMID: 38351531] - Fangfang Cai, Dangran Li, Yawen Xie, Xiaoyang Wang, Hailin Ma, Huangru Xu, Jian Cheng, Hongqin Zhuang, Zi-Chun Hua. Sulfide:quinone oxidoreductase alleviates ferroptosis in acute kidney injury via ameliorating mitochondrial dysfunction of renal tubular epithelial cells.
Redox biology.
2024 Feb; 69(?):102973. doi:
10.1016/j.redox.2023.102973. [PMID: 38052107] - Jihan Hussein, Mona El-Bana, Yasmin Abdel-Latif, Samah El-Sayed, Sahar Shaarawy, Dalia Medhat. Moringa oleifera leaves extract loaded gold nanoparticles offers a promising approach in protecting against experimental nephrotoxicity.
Prostaglandins & other lipid mediators.
2024 Feb; 170(?):106800. doi:
10.1016/j.prostaglandins.2023.106800. [PMID: 38029886] - Yuhan Lin, Rui Liang, Kairong Xie, Tingting Ma, Jigui Zhang, Tao Xu, Aimei Wang, Shuangyue Liu. Puerarin inhibits cisplatin-induced ototoxicity in mice through regulation of TRPV1-dependent calcium overload.
Biochemical pharmacology.
2024 Feb; 220(?):115962. doi:
10.1016/j.bcp.2023.115962. [PMID: 38043717] - Jiaxi Fang, Luping Wang, Di Zhang, Yan Liang, Shouxin Li, Jingkui Tian, Qiang He, Juan Jin, Wei Zhu. Integrative analysis of transcriptome and metabolome provide new insights into mechanisms of Capilliposide A against cisplatin-induced nephrotoxicity.
Journal of pharmaceutical and biomedical analysis.
2024 Jan; 238(?):115814. doi:
10.1016/j.jpba.2023.115814. [PMID: 37976990] - Shugao Han, Xi Yang, Jing Zhuang, Qing Zhou, Jingjing Wang, Lixin Ru, Furong Niu, Wei Mao. α-Hederin promotes ferroptosis and reverses cisplatin chemoresistance in non-small cell lung cancer.
Aging.
2024 Jan; 16(2):1298-1317. doi:
10.18632/aging.205408. [PMID: 38244586] - Mohammad Reza Karimzadeh, Afsane Masoudi Chelegahi, Shahrzad Shahbazi, Somayeh Reiisi. Co-treatment of silymarin and cisplatin inhibited cell proliferation, induced apoptosis in ovarian cancer.
Molecular biology reports.
2024 Jan; 51(1):118. doi:
10.1007/s11033-023-09026-8. [PMID: 38227082] - Dengshuai Wei, Junning Fan, Jianqin Yan, Chaolong Liu, Jie Cao, Chun Xu, Yong Sun, Haihua Xiao. Nuclear-Targeting Lipid PtIV Prodrug Amphiphile Cooperates with siRNA for Enhanced Cancer Immunochemotherapy by Amplifying Pt-DNA Adducts and Reducing Phosphatidylserine Exposure.
Journal of the American Chemical Society.
2024 Jan; 146(1):1185-1195. doi:
10.1021/jacs.3c12706. [PMID: 38148611] - Yang-Che Wu, Chin-Sheng Huang, Ming-Shou Hsieh, Chih-Ming Huang, Syahru Agung Setiawan, Chi-Tai Yeh, Kuang-Tai Kuo, Shao-Cheng Liu. Targeting of FSP1 regulates iron homeostasis in drug-tolerant persister head and neck cancer cells via lipid-metabolism-driven ferroptosis.
Aging.
2024 Jan; 16(1):627-647. doi:
10.18632/aging.205409. [PMID: 38206305] - Xinran Li, Jieya Shi, Yuou Teng, Zhen Liu. The preventative effect of Baihe Gujin Pill on cisplatin-induced acute kidney injury by activating the PI3K/AKT and suppressing the NF-κB/MAPK pathways.
Journal of ethnopharmacology.
2024 Jan; 318(Pt B):117071. doi:
10.1016/j.jep.2023.117071. [PMID: 37619855] - Zhikun Liu, Jinyuan Cai, Guiyang Jiang, Meng Wang, Chuang Wu, Kangning Su, Weiwei Hu, Yaxian Huang, Chunhao Yu, Xiaochao Huang, Guoxiu Cao, Hengshan Wang. Novel Platinum(IV) complexes intervene oxaliplatin resistance in colon cancer via inducing ferroptosis and apoptosis.
European journal of medicinal chemistry.
2024 Jan; 263(?):115968. doi:
10.1016/j.ejmech.2023.115968. [PMID: 37995563] - Changjun Zhang, Yi Lu, Jingqi Zhang, Anjie Zang, Jinhui Ren, Zhiyuan Zheng, Miaoliang Fan, Yuanyuan Xie. Novel 3-hydroxypyridin-4(1H)-One derivatives as ferroptosis inhibitors with iron-chelating and reactive oxygen species scavenging activities and therapeutic effect in cisplatin-induced cytotoxicity.
European journal of medicinal chemistry.
2024 Jan; 263(?):115945. doi:
10.1016/j.ejmech.2023.115945. [PMID: 37976709] - Wenjie Huang, Fang Wen, Peipei Yang, Ye Li, Qiurong Li, Peng Shu. Yi-qi-hua-yu-jie-du decoction induces ferroptosis in cisplatin-resistant gastric cancer via the AKT/GSK3β/NRF2/GPX4 axis.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2024 Jan; 123(?):155220. doi:
10.1016/j.phymed.2023.155220. [PMID: 38056149] - Jiaxing Zhang, Liwei Gu, Yumao Jiang, Yun Ma, Ziyue Zhang, Shengnan Shen, Shuo Shen, Qing Peng, Wei Xiao. Artesunate-Nanoliposome-TPP, a Novel Drug Delivery System That Targets the Mitochondria, Attenuates Cisplatin-Induced Acute Kidney Injury by Suppressing Oxidative Stress and Inflammatory Effects.
International journal of nanomedicine.
2024; 19(?):1385-1408. doi:
10.2147/ijn.s444076. [PMID: 38371457] - Lian Peng, Renyi Yang, Zhibing Wang, Huiying Jian, Xiaoning Tan, Jian Li, Zuomei He, Rui Huang, Puhua Zeng, Wenhui Gao. Polyphyllin II (PPII) Enhances the Sensitivity of Multidrug-resistant A549/DDP Cells to Cisplatin by Modulating Mitochondrial Energy Metabolism.
In vivo (Athens, Greece).
2024 Jan; 38(1):213-225. doi:
10.21873/invivo.13428. [PMID: 38148070] - Yi Liu, Shuying Dai, Yixiao Xu, Yuying Xiang, Yao Zhang, Zeting Xu, Lin Sun, Gao-Chen-Xi Zhang, Qijin Shu. Integration of Network Pharmacology and Experimental Validation to Explore Jixueteng - Yinyanghuo Herb Pair Alleviate Cisplatin-Induced Myelosuppression.
Integrative cancer therapies.
2024 Jan; 23(?):15347354241237969. doi:
10.1177/15347354241237969. [PMID: 38462913] - Run-Run Shan, Ju-Tao Yu, Shao-Fei Zhang, Man-Man Xie, Rui Hou, Chun-Ya Xie, Ze-Hui Dong, Qin Yang, Xiao-Wei Hu, Yu-Hang Dong, Yao Zhang, Xiu-Feng Luo, Zong-Yu Cui, Xiao-Ying Liu, Yun-Chang Xie, Jia-Gen Wen, Ming-Ming Liu, Juan Jin, Qi Chen, Xiao-Ming Meng. Madecassoside alleviates acute kidney injury by regulating JNK-mediated oxidative stress and programmed cell death.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2024 Jan; 123(?):155252. doi:
10.1016/j.phymed.2023.155252. [PMID: 38056145] - Min Wu, Jiuqing Xie, Yajing Xing, Lin Zhang, Huang Chen, Bin Tang, Miaoran Zhou, Shiyi Lv, Dongxia Huang, Shuyi Jian, Cili Zhou, Mingyao Liu, Weikai Guo, Yihua Chen, Zhengfang Yi. Selectively targeting BCL6 using a small molecule inhibitor is a potential therapeutic strategy for ovarian cancer.
International journal of biological sciences.
2024; 20(2):486-501. doi:
10.7150/ijbs.86303. [PMID: 38169532] - Cagla Tekin, Melis Ercelik, Pavel Dunaev, Aigul Galembikova, Gulcin Tezcan, Secil Ak Aksoy, Ferah Budak, Ozgen Isık, Nesrin Ugras, Sergei Boichuk, Berrin Tunca. Leaf Extract from European Olive (Olea europaea L.) Post-Transcriptionally Suppresses the Epithelial-Mesenchymal Transition and Sensitizes Gastric Cancer Cells to Chemotherapy.
Biochemistry. Biokhimiia.
2024 Jan; 89(1):97-115. doi:
10.1134/s0006297924010061. [PMID: 38467548] - Quoc Manh Nguyen, Pierre-François Dupré, Mathieu Berchel, Rosy Ghanem, Paul-Alain Jaffrès, Frédérique d'Arbonneau, Tristan Montier. BSV163/DOPE-mediated TRAIL gene transfection acts synergistically with chemotherapy against cisplatin-resistant ovarian cancer.
Chemical biology & drug design.
2024 01; 103(1):e14357. doi:
10.1111/cbdd.14357. [PMID: 37731182] - Zhen-Liang Nong, Kun Zhao, Ye Wang, Zhu Yu, Cong-Jun Wang, Jun-Qiang Chen. CLIC1-mediated autophagy confers resistance to DDP in gastric cancer.
Anti-cancer drugs.
2024 01; 35(1):1-11. doi:
10.1097/cad.0000000000001518. [PMID: 37104099] - Ran Cheng, Rui-Min Tian, Li-Hua Huang, Xiao-Wan Wang, Shan Guo, Ai-Jun Wu, Chuang Li, Jing Chen, Shu-Ju Li, Ming Chen, Wei Mao, Peng Xu. [Effect and mechanism of Jiedu Huoxue Decoction in regulating YAP/ACSL4 pathway to inhibit ferroptosis in treatment of acute kidney injury].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2024 Jan; 49(1):151-161. doi:
10.19540/j.cnki.cjcmm.20230829.401. [PMID: 38403348] - Mengmeng Zhao, Jialing Guo, Chaoying Tian, Mei Yan, Yingying Zhou, Chenxin Liu, Mengxue Pang, Bin Du, Genyang Cheng. Dual-targeted nanoparticles with removing ROS inside and outside mitochondria for acute kidney injury treatment.
Nanomedicine : nanotechnology, biology, and medicine.
2024 Jan; 55(?):102725. doi:
10.1016/j.nano.2023.102725. [PMID: 38007068] - Sung Wan Kang, Ok-Ju Kang, Ji-Young Lee, Hyejeong Kim, Hunsoon Jung, Hongjoong Kim, Shin-Wha Lee, Yong Man Kim, Eun Kyung Choi. Evaluation of the anti-cancer efficacy of lipid nanoparticles containing siRNA against HPV16 E6/E7 combined with cisplatin in a xenograft model of cervical cancer.
PloS one.
2024; 19(2):e0298815. doi:
10.1371/journal.pone.0298815. [PMID: 38363779] - Sicong Hou, Tiantian Zhao, Bin Deng, Caimin Li, Wenqian Li, Haifeng Huang, Qinglei Hang. USP10 promotes migration and cisplatin resistance in esophageal squamous cell carcinoma cells.
Medical oncology (Northwood, London, England).
2023 Dec; 41(1):33. doi:
10.1007/s12032-023-02272-7. [PMID: 38150085] - Cian Zhang, Yongying Liu, Jing Zhao, Jingyu Xu, Bei Pei, Xuan Liu, Xiaoqiang Yue. KIAA0101 promotes cisplatin resistance through regulating cell apoptosis in lung cancer cells.
Cellular and molecular biology (Noisy-le-Grand, France).
2023 Dec; 69(14):172-176. doi:
10.14715/cmb/2023.69.14.28. [PMID: 38279448] - Daniela S C Bispo, Marlene Correia, Tatiana J Carneiro, Ana S Martins, Aliana A N Reis, Ana L M Batista de Carvalho, Maria P M Marques, Ana M Gil. Impact of Conventional and Potential New Metal-Based Drugs on Lipid Metabolism in Osteosarcoma MG-63 Cells.
International journal of molecular sciences.
2023 Dec; 24(24):. doi:
10.3390/ijms242417556. [PMID: 38139388] - Qingchang Wu, Miao Chen, Yao Li, Xiangyun Zhao, Cailian Fan, Yi Dai. Paeoniflorin Alleviates Cisplatin-Induced Diminished Ovarian Reserve by Restoring the Function of Ovarian Granulosa Cells via Activating FSHR/cAMP/PKA/CREB Signaling Pathway.
Molecules (Basel, Switzerland).
2023 Dec; 28(24):. doi:
10.3390/molecules28248123. [PMID: 38138611] - Xiaojia Guo, Valerie Blanc, Nicholas O Davidson, Heino Velazquez, Tian-Min Chen, Dennis G Moledina, Gilbert W Moeckel, Robert L Safirstein, Gary V Desir. APOBEC-1 deletion enhances cisplatin-induced acute kidney injury.
Scientific reports.
2023 12; 13(1):22255. doi:
10.1038/s41598-023-49575-3. [PMID: 38097707] - Xing-Qiang Dong, Li-Kai Chu, Xu Cao, Qian-Wei Xiong, Yi-Ming Mao, Ching-Hsien Chen, Yun-Li Bi, Jun Liu, Xiang-Ming Yan. Glutathione metabolism rewiring protects renal tubule cells against cisplatin-induced apoptosis and ferroptosis.
Redox report : communications in free radical research.
2023 Dec; 28(1):2152607. doi:
10.1080/13510002.2022.2152607. [PMID: 36692085] - Mengnan Zhao, Tao Lu, Guoshu Bi, Zhengyang Hu, Jiaqi Liang, Yunyi Bian, Mingxiang Feng, Cheng Zhan. PLK1 regulating chemoradiotherapy sensitivity of esophageal squamous cell carcinoma through pentose phosphate pathway/ferroptosis.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2023 Dec; 168(?):115711. doi:
10.1016/j.biopha.2023.115711. [PMID: 37879213] - Pengyu Geng, Jinhui Zhao, Qi Li, Xiaolin Wang, Wangshu Qin, Ting Wang, Xianzhe Shi, Xinyu Liu, Jia Chen, Hongdeng Qiu, Guowang Xu. Z-Ligustilide Combined with Cisplatin Reduces PLPP1-Mediated Phospholipid Synthesis to Impair Cisplatin Resistance in Lung Cancer.
International journal of molecular sciences.
2023 Dec; 24(23):. doi:
10.3390/ijms242317046. [PMID: 38069368] - Ilya Iryani Mahmod, Intan Safinar Ismail, Yahaya M Normi, Siok-Geok Chong. Protective effect of Clinacanthus nutans in cisplatin-induced nephrotoxicity on human kidney cell (PCS-400-010) elucidated by an LCMS-based metabolomics approach.
Biomedical chromatography : BMC.
2023 Dec; 37(12):e5750. doi:
10.1002/bmc.5750. [PMID: 37778127] - Melva Louisa, Erico Wanafri, Wawaimuli Arozal, Ni Made Dwi Sandhiutami, Ahmad Muhammad Basalamah. Nanocurcumin preserves kidney function and haematology parameters in DMBA-induced ovarian cancer treated with cisplatin via its antioxidative and anti-inflammatory effect in rats.
Pharmaceutical biology.
2023 Dec; 61(1):298-305. doi:
10.1080/13880209.2023.2166965. [PMID: 36708211] - Hisakatsu Sone, Tae Jin Lee, Byung Rho Lee, Dan Heo, Sekyung Oh, Sang-Ho Kwon. MicroRNA-mediated attenuation of branched-chain amino acid catabolism promotes ferroptosis in chronic kidney disease.
Nature communications.
2023 Nov; 14(1):7814. doi:
10.1038/s41467-023-43529-z. [PMID: 38016961] - Kaichuang Sun, Lu Yuan, Shen Chen, Yong Sun, Dengshuai Wei. Alendronate PtIV Prodrug Amphiphile for Enhanced Chemotherapy Targeting and Bone Destruction Inhibition in Osteosarcoma.
Advanced healthcare materials.
2023 Nov; ?(?):e2302746. doi:
10.1002/adhm.202302746. [PMID: 37988194] - Zhiguang Zhang, Boya Liang, Wugemo Jike, Runtian Li, Xinxin Su, Jie Yu, Tongxiang Liu. The Protective Effect of Marsdenia tenacissima against Cisplatin-Induced Nephrotoxicity Mediated by Inhibiting Oxidative Stress, Inflammation, and Apoptosis.
Molecules (Basel, Switzerland).
2023 Nov; 28(22):. doi:
10.3390/molecules28227582. [PMID: 38005304] - Xiang Zheng, Lei Yang, Wei Zhai, Nana Geng, Zhimin Zhang, Xueying Li, Mingsong Wu. Synergistic anticancer activity of cisplatin combined with tannic acid enhances apoptosis in lung cancer through the PERK-ATF4 pathway.
European journal of medical research.
2023 Oct; 28(1):462. doi:
10.1186/s40001-023-01420-z. [PMID: 37885044] - Qiming Gong, Tengfang Lai, Liudan Liang, Yan Jiang, Fahui Liu. Targeted inhibition of CX3CL1 limits podocytes ferroptosis to ameliorate cisplatin-induced acute kidney injury.
Molecular medicine (Cambridge, Mass.).
2023 10; 29(1):140. doi:
10.1186/s10020-023-00733-3. [PMID: 37875838] - Jin Tian, Lin Long, Jianhua Zang, Wei Liu, Peng Liu, Lili Zhao, Xin Liang, Jun Xiao. Effect of hyperthermia on intestinal microecology, immune function, and progression-free survival in patients with advanced unresectable lung adenocarcinoma.
Scientific reports.
2023 10; 13(1):17223. doi:
10.1038/s41598-023-44350-w. [PMID: 37821661] - Yadie Xiang, Xianke Zhou, Hong Zhou, Dier Li, Menghua Zhong, Xue Hong, Dongyan Song, Yinyi Long, Xi Zeng, Yudan Chen, Jiayi Zhou, Dongning Liang, Haiyan Fu. Limonin ameliorates cisplatin-induced acute liver injury by inhibiting 11β-hydroxysteroid dehydrogenase type 1.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2023 Oct; 168(?):115680. doi:
10.1016/j.biopha.2023.115680. [PMID: 37832403] - Fei Deng, Heping Zhang, Wei Zhou, Shijie Ma, Yuwei Kang, Wei Yang, Liangbin Zhao, Wei Qin. TRPA1 promotes cisplatin-induced acute kidney injury via regulating the endoplasmic reticulum stress-mitochondrial damage.
Journal of translational medicine.
2023 Oct; 21(1):695. doi:
10.1186/s12967-023-04351-9. [PMID: 37798747] - Cai-Wei Qiu, Bo Chen, Hui-Feng Zhu, Ying-Lan Liang, Lin-Shen Mao. Gastrodin alleviates cisplatin nephrotoxicity by inhibiting ferroptosis via the SIRT1/FOXO3A/GPX4 signaling pathway.
Journal of ethnopharmacology.
2023 Oct; ?(?):117282. doi:
10.1016/j.jep.2023.117282. [PMID: 37802374] - Liting Zhong, Xuejiao Meng, Jingjing Huang, Wenwen Hao, Yajing Zuo. Expression of YAP suppresses cell proliferation and elevates the sensitivity of chemotherapy in retinoblastoma cells through lipid-peroxidation induced ferroptosis.
Chinese clinical oncology.
2023 Oct; 12(5):52. doi:
10.21037/cco-23-97. [PMID: 37964544] - N R Hakobyan, Zh V Yavroyan, A G Hovhannisyan, E S Gevorgyan. Cisplatin and progesterone separate and combined action on rat brain nuclear phospholipids content.
Prostaglandins & other lipid mediators.
2023 10; 168(?):106750. doi:
10.1016/j.prostaglandins.2023.106750. [PMID: 37247723] - Yongsen Wang, Shuting Tang, Lingling Li, Cheng Sun, Yaru Liu, Yujie Zhao. Depletion of circPDSS1 inhibits ITGA11 production to confer cisplatin sensitivity through miR-515-5p in gastric cancer.
Journal of chemotherapy (Florence, Italy).
2023 Oct; 35(6):514-526. doi:
10.1080/1120009x.2022.2151702. [PMID: 36484486] - Firoozeh Niazvand, Atefeh Ashtari, Narges Chamkouri, Mahdi Azari. Hepatoprotective effects of Alpinia officinarum rhizome extract on cisplatin-induced hepatotoxicity in rats: A biochemical, histopathological and immunohistochemical study.
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS).
2023 Sep; 80(?):127306. doi:
10.1016/j.jtemb.2023.127306. [PMID: 37757646] - Wanhui Wei, Yuanyuan Lu, Qian Hu, Jinwen Yin, Youwei Wang, Heng Zhang, Qiu Zhao, Lan Liu. Synergistic antitumor efficacy of gemcitabine and cisplatin to induce ferroptosis in pancreatic ductal adenocarcinoma via Sp1-SAT1-polyamine metabolism pathway.
Cellular oncology (Dordrecht).
2023 Sep; ?(?):. doi:
10.1007/s13402-023-00870-1. [PMID: 37684512] - Lulu Wang, Lei Li, Zhenyi Wang, Pu Zhang, Jing Zhang. Gut Microbiota Combined with Metabolomics Reveal the Mechanisms of Sika Deer Antler Protein on Cisplatin-Induced Hepatorenal Injury in Mice.
Molecules (Basel, Switzerland).
2023 Sep; 28(18):. doi:
10.3390/molecules28186463. [PMID: 37764239] - Yiding Wang, Xiaoling Pang, Yuexin Liu, Guiling Mu, Qian Wang. SOCS1 acts as a ferroptosis driver to inhibit the progression and chemotherapy resistance of triple-negative breast cancer.
Carcinogenesis.
2023 Sep; ?(?):. doi:
10.1093/carcin/bgad060. [PMID: 37665951] - Zeinab Mokhtari, Effat Seyedhashemi, Maryam Eftekhari, Shiva Ghasemi, Akram Sabouri, Kazem Abbaszadeh-Goudarzi, Morteza Abuali, Hanie Azimi, Prashant Kesharwani, Hossein Pourghadamyari, Amirhossein Sahebkar. Enhancement of cisplatin-induced apoptosis by saffron in human lung cancer cells.
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS).
2023 Sep; 79(?):127229. doi:
10.1016/j.jtemb.2023.127229. [PMID: 37315393] - Alaaeldin Ahmed Hamza, Gehan Hussein Heeba, Soha Osama Hassanin, Hanan Mohamed Elwy, Amany Abdelrehim Bekhit, Amr Amin. Hibiscus-cisplatin combination treatment decreases liver toxicity in rats while increasing toxicity in lung cancer cells via oxidative stress- apoptosis pathway.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2023 Sep; 165(?):115148. doi:
10.1016/j.biopha.2023.115148. [PMID: 37450997] - Xiaolu Zhang, Ying Xu, Wei Zhang, Bingyu Yang, Yue Zhang, Zhanjun Jia, Songming Huang, Aihua Zhang, Shuzhen Li. TRAF1 improves cisplatin-induced acute kidney injury via inhibition of inflammation and metabolic disorders.
Biochimica et biophysica acta. General subjects.
2023 09; 1867(9):130423. doi:
10.1016/j.bbagen.2023.130423. [PMID: 37419425] - Ching-Huey Yang, Yun-Ching Chang, Chung-Chi Hsu, Cheng-Han Lin, I-Ju Chen, Yen-Ting Wu, Yu-Yan Lan. Fucoidan Enhances Cisplatin-induced Effects on SCC-25 Human Oral Cancer Cells by Inhibiting the PI3K/AKT Pathway.
Anticancer research.
2023 Sep; 43(9):4015-4022. doi:
10.21873/anticanres.16589. [PMID: 37648299] - Song-Yi Lin, Chia-Lin Chang, Kuo-Tong Liou, Yao-Kai Kao, Yea-Hwey Wang, Cher-Chia Chang, Terry B J Kuo, Hung-Tse Huang, Cheryl C H Yang, Chia-Ching Liaw, Yuh-Chiang Shen. The protective role of Achyranthes aspera extract against cisplatin-induced nephrotoxicity by alleviating oxidative stress, inflammation, and PANoptosis.
Journal of ethnopharmacology.
2023 Aug; 319(Pt 1):117097. doi:
10.1016/j.jep.2023.117097. [PMID: 37648176] - Minling Pan, Zhen Wang, Yiyi Wang, Xianqin Jiang, Yali Fan, Fanghua Gong, Yunpeng Sun, Dezhong Wang. Celastrol alleviated acute kidney injury by inhibition of ferroptosis through Nrf2/GPX4 pathway.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2023 Aug; 166(?):115333. doi:
10.1016/j.biopha.2023.115333. [PMID: 37598476] - Ping Zhao, Fei Yuan, Lijuan Xu, Zhenghao Jin, Yang Liu, Jing Su, Lin Yuan, Lei Peng, Chaofu Wang, Guoxin Zhang. HKDC1 reprograms lipid metabolism to enhance gastric cancer metastasis and cisplatin resistance via forming a ribonucleoprotein complex.
Cancer letters.
2023 08; 569(?):216305. doi:
10.1016/j.canlet.2023.216305. [PMID: 37423558] - Esrafil Mansouri, Zeinab Shafiei Seifabadi, Nastaran Azarbarz, Maasoumeh Zare Moaiedi. Effects of sodium hydrosulfide (NaHS) on cisplatin-induced hepatic and cardiac toxicity.
Drug and chemical toxicology.
2023 Aug; ?(?):1-8. doi:
10.1080/01480545.2023.2242008. [PMID: 37553904]
