3-Acetyloxy-2-aminopropanoic acid (BioDeep_00000853459)
代谢物信息卡片
3-Acetyloxy-2-aminopropanoic acid
化学式: C5H9NO4 (147.0531554)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(=O)OCC(C(=O)O)N
InChI: InChI=1S/C5H9NO4/c1-3(7)10-2-4(6)5(8)9/h4H,2,6H2,1H3,(H,8,9)
相关代谢途径
Reactome(0)
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
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Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
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0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Marcela de Paiva Foletto-Felipe, Josielle Abrahão, Rita de Cássia Siqueira-Soares, Isabela de Carvalho Contesoto, Luiz Henryque Escher Grizza, Guilherme Henrique Gonçalves de Almeida, Renato Polimeni Constantin, Gisele Strieder Philippsen, Flavio Augusto Vicente Seixas, Paulo Sérgio Alves Bueno, Marco Aurélio Schüler de Oliveira, Rodrigo Polimeni Constantin, Wanderley Dantas Dos Santos, Osvaldo Ferrarese-Filho, Rogério Marchiosi. Inhibition of O-acetylserine (thiol) lyase as a promising new mechanism of action for herbicides.
Plant physiology and biochemistry : PPB.
2023 Nov; 204(?):108127. doi:
10.1016/j.plaphy.2023.108127. [PMID: 37890229] - Anastasia Apodiakou, Rainer Hoefgen. New insights into the regulation of plant metabolism by O-acetyl-serine: sulfate and beyond.
Journal of experimental botany.
2023 Apr; ?(?):. doi:
10.1093/jxb/erad124. [PMID: 37025061] - Assylay Kurmanbayeva, Aizat Bekturova, Aigerim Soltabayeva, Dinara Oshanova, Zhadyrassyn Nurbekova, Sudhakar Srivastava, Poonam Tiwari, Arvind Kumar Dubey, Moshe Sagi. Active O-acetylserine-(thiol) lyase A and B confer improved selenium resistance and degrade l-Cys and l-SeCys in Arabidopsis.
Journal of experimental botany.
2022 04; 73(8):2525-2539. doi:
10.1093/jxb/erac021. [PMID: 35084469] - Yasuyuki Matoba, Masafumi Noda, Tomoki Yoshida, Kosuke Oda, Yuka Ezumi, Chiaki Yasutake, Hisae Izuhara-Kihara, Narandarai Danshiitsoodol, Takanori Kumagai, Masanori Sugiyama. Catalytic specificity of the Lactobacillus plantarum cystathionine γ-lyase presumed by the crystallographic analysis.
Scientific reports.
2020 09; 10(1):14886. doi:
10.1038/s41598-020-71756-7. [PMID: 32913258] - Sunlin Chi, Yuli Qin, Weihong Xu, Yourong Chai, Deyu Feng, Yanhua Li, Tao Li, Mei Yang, Zhangmi He. Differences of Cd uptake and expression of OAS and IRT genes in two varieties of ryegrasses.
Environmental science and pollution research international.
2019 May; 26(14):13717-13724. doi:
10.1007/s11356-018-2509-x. [PMID: 29909534] - Zhen Wang, Jie-Li Mao, Ying-Jun Zhao, Chuan-You Li, Cheng-Bin Xiang. L-Cysteine inhibits root elongation through auxin/PLETHORA and SCR/SHR pathway in Arabidopsis thaliana.
Journal of integrative plant biology.
2015 Feb; 57(2):186-97. doi:
10.1111/jipb.12213. [PMID: 24798139] - Zongyong Tong, Can Xie, Lei Ma, Liping Liu, Yongsheng Jin, Jiangli Dong, Tao Wang. Co-expression of bacterial aspartate kinase and adenylylsulfate reductase genes substantially increases sulfur amino acid levels in transgenic alfalfa (Medicago sativa L.).
PloS one.
2014; 9(2):e88310. doi:
10.1371/journal.pone.0088310. [PMID: 24520364] - Anna Wawrzyńska, Agata Kurzyk, Monika Mierzwińska, Danuta Płochocka, Grzegorz Wieczorek, Agnieszka Sirko. Direct targeting of Arabidopsis cysteine synthase complexes with synthetic polypeptides to selectively deregulate cysteine synthesis.
Plant science : an international journal of experimental plant biology.
2013 Jun; 207(?):148-57. doi:
10.1016/j.plantsci.2013.02.016. [PMID: 23602110] - Hans-Michael Hubberten, Agnieszka Drozd, Bich V Tran, Holger Hesse, Rainer Hoefgen. Local and systemic regulation of sulfur homeostasis in roots of Arabidopsis thaliana.
The Plant journal : for cell and molecular biology.
2012 Nov; 72(4):625-35. doi:
10.1111/j.1365-313x.2012.05105.x. [PMID: 22775482] - Dengqun Liao, Agnieszka Pajak, Steven R Karcz, B Patrick Chapman, Andrew G Sharpe, Ryan S Austin, Raju Datla, Sangeeta Dhaubhadel, Frédéric Marsolais. Transcripts of sulphur metabolic genes are co-ordinately regulated in developing seeds of common bean lacking phaseolin and major lectins.
Journal of experimental botany.
2012 Oct; 63(17):6283-95. doi:
10.1093/jxb/ers280. [PMID: 23066144] - Colette A Matthewman, Cintia G Kawashima, Dalibor Húska, Tibor Csorba, Tamas Dalmay, Stanislav Kopriva. miR395 is a general component of the sulfate assimilation regulatory network in Arabidopsis.
FEBS letters.
2012 Sep; 586(19):3242-8. doi:
10.1016/j.febslet.2012.06.044. [PMID: 22771787] - Markus Wirtz, Katherine F M Beard, Chun Pong Lee, Achim Boltz, Markus Schwarzländer, Christopher Fuchs, Andreas J Meyer, Corinna Heeg, Lee J Sweetlove, R George Ratcliffe, Rüdiger Hell. Mitochondrial cysteine synthase complex regulates O-acetylserine biosynthesis in plants.
The Journal of biological chemistry.
2012 Aug; 287(33):27941-7. doi:
10.1074/jbc.m112.372656. [PMID: 22730323] - Galina Brychkova, Dmitry Yarmolinsky, Yvonne Ventura, Moshe Sagi. A novel in-gel assay and an improved kinetic assay for determining in vitro sulfite reductase activity in plants.
Plant & cell physiology.
2012 Aug; 53(8):1507-16. doi:
10.1093/pcp/pcs084. [PMID: 22685081] - Hannah Birke, Florian H Haas, Luit J De Kok, Janneke Balk, Markus Wirtz, Rüdiger Hell. Cysteine biosynthesis, in concert with a novel mechanism, contributes to sulfide detoxification in mitochondria of Arabidopsis thaliana.
The Biochemical journal.
2012 Jul; 445(2):275-83. doi:
10.1042/bj20120038. [PMID: 22551219] - Hans-Michael Hubberten, Sebastian Klie, Camila Caldana, Thomas Degenkolbe, Lothar Willmitzer, Rainer Hoefgen. Additional role of O-acetylserine as a sulfur status-independent regulator during plant growth.
The Plant journal : for cell and molecular biology.
2012 May; 70(4):666-77. doi:
10.1111/j.1365-313x.2012.04905.x. [PMID: 22243437] - Bok-Rye Lee, Anna Koprivova, Stanislav Kopriva. The key enzyme of sulfate assimilation, adenosine 5'-phosphosulfate reductase, is regulated by HY5 in Arabidopsis.
The Plant journal : for cell and molecular biology.
2011 Sep; 67(6):1042-54. doi:
10.1111/j.1365-313x.2011.04656.x. [PMID: 21623972] - Stephan Krueger, Andrea Donath, M Carmen Lopez-Martin, Rainer Hoefgen, Cecilia Gotor, Holger Hesse. Impact of sulfur starvation on cysteine biosynthesis in T-DNA mutants deficient for compartment-specific serine-acetyltransferase.
Amino acids.
2010 Oct; 39(4):1029-42. doi:
10.1007/s00726-010-0580-9. [PMID: 20379751] - Linda Tabe, Markus Wirtz, Lisa Molvig, Michel Droux, Ruediger Hell. Overexpression of serine acetlytransferase produced large increases in O-acetylserine and free cysteine in developing seeds of a grain legume.
Journal of experimental botany.
2010 Mar; 61(3):721-33. doi:
10.1093/jxb/erp338. [PMID: 19939888] - Karen Loizeau, Veerle De Brouwer, Bernadette Gambonnet, Agnès Yu, Jean-Pierre Renou, Dominique Van Der Straeten, Willy E Lambert, Fabrice Rébeillé, Stéphane Ravanel. A genome-wide and metabolic analysis determined the adaptive response of Arabidopsis cells to folate depletion induced by methotrexate.
Plant physiology.
2008 Dec; 148(4):2083-95. doi:
10.1104/pp.108.130336. [PMID: 18931140] - Florian H Haas, Corinna Heeg, Rafael Queiroz, Andrea Bauer, Markus Wirtz, Rüdiger Hell. Mitochondrial serine acetyltransferase functions as a pacemaker of cysteine synthesis in plant cells.
Plant physiology.
2008 Oct; 148(2):1055-67. doi:
10.1104/pp.108.125237. [PMID: 18753283] - Mutsumi Watanabe, Keiichi Mochida, Tomohiko Kato, Satoshi Tabata, Naoko Yoshimoto, Masaaki Noji, Kazuki Saito. Comparative genomics and reverse genetics analysis reveal indispensable functions of the serine acetyltransferase gene family in Arabidopsis.
The Plant cell.
2008 Sep; 20(9):2484-96. doi:
10.1105/tpc.108.060335. [PMID: 18776059] - Małgorzata Lewandowska, Agnieszka Sirko. Recent advances in understanding plant response to sulfur-deficiency stress.
Acta biochimica Polonica.
2008; 55(3):457-71. doi:
10.18388/abp.2008_3051. [PMID: 18787711] - Markus Wirtz, Rüdiger Hell. Functional analysis of the cysteine synthase protein complex from plants: structural, biochemical and regulatory properties.
Journal of plant physiology.
2006 Feb; 163(3):273-86. doi:
10.1016/j.jplph.2005.11.013. [PMID: 16386330] - Wendy Ann Peer, Mehrzad Mahmoudian, John L Freeman, Brett Lahner, Elizabeth L Richards, Roger D Reeves, Angus S Murphy, David E Salt. Assessment of plants from the Brassicaceae family as genetic models for the study of nickel and zinc hyperaccumulation.
The New phytologist.
2006; 172(2):248-60. doi:
10.1111/j.1469-8137.2006.01820.x. [PMID: 16995913] - Masami Yokota Hirai, Marion Klein, Yuuta Fujikawa, Mitsuru Yano, Dayan B Goodenowe, Yasuyo Yamazaki, Shigehiko Kanaya, Yukiko Nakamura, Masahiko Kitayama, Hideyuki Suzuki, Nozomu Sakurai, Daisuke Shibata, Jim Tokuhisa, Michael Reichelt, Jonathan Gershenzon, Jutta Papenbrock, Kazuki Saito. Elucidation of gene-to-gene and metabolite-to-gene networks in arabidopsis by integration of metabolomics and transcriptomics.
The Journal of biological chemistry.
2005 Jul; 280(27):25590-5. doi:
10.1074/jbc.m502332200. [PMID: 15866872] - Laura Hopkins, Saroj Parmar, Anna Błaszczyk, Holger Hesse, Rainer Hoefgen, Malcolm J Hawkesford. O-acetylserine and the regulation of expression of genes encoding components for sulfate uptake and assimilation in potato.
Plant physiology.
2005 May; 138(1):433-40. doi:
10.1104/pp.104.057521. [PMID: 15805476] - Naoko Ohkama-Ohtsu, Ichiro Kasajima, Toru Fujiwara, Satoshi Naito. Isolation and characterization of an Arabidopsis mutant that overaccumulates O-Acetyl-L-Ser.
Plant physiology.
2004 Oct; 136(2):3209-22. doi:
10.1104/pp.104.047068. [PMID: 15466229] - Pasquale Chiaiese, Naoko Ohkama-Ohtsu, Lisa Molvig, Robert Godfree, Hugh Dove, Charles Hocart, Toru Fujiwara, T J V Higgins, Linda M Tabe. Sulphur and nitrogen nutrition influence the response of chickpea seeds to an added, transgenic sink for organic sulphur.
Journal of experimental botany.
2004 Aug; 55(404):1889-901. doi:
10.1093/jxb/erh198. [PMID: 15234997] - John L Freeman, Michael W Persans, Ken Nieman, Carrie Albrecht, Wendy Peer, Ingrid J Pickering, David E Salt. Increased glutathione biosynthesis plays a role in nickel tolerance in thlaspi nickel hyperaccumulators.
The Plant cell.
2004 Aug; 16(8):2176-91. doi:
10.1105/tpc.104.023036. [PMID: 15269333] - Holger Hesse, Nadine Trachsel, Marianne Suter, Stanislav Kopriva, Peter von Ballmoos, Heinz Rennenberg, Christian Brunold. Effect of glucose on assimilatory sulphate reduction in Arabidopsis thaliana roots.
Journal of experimental botany.
2003 Jul; 54(388):1701-9. doi:
10.1093/jxb/erg177. [PMID: 12754263] - Masami Yokota Hirai, Toru Fujiwara, Motoko Awazuhara, Tomoko Kimura, Masaaki Noji, Kazuki Saito. Global expression profiling of sulfur-starved Arabidopsis by DNA macroarray reveals the role of O-acetyl-l-serine as a general regulator of gene expression in response to sulfur nutrition.
The Plant journal : for cell and molecular biology.
2003 Feb; 33(4):651-63. doi:
10.1046/j.1365-313x.2003.01658.x. [PMID: 12609039] - George Tsakraklides, Melinda Martin, Radhika Chalam, Mitchell C Tarczynski, Ahlert Schmidt, Thomas Leustek. Sulfate reduction is increased in transgenic Arabidopsis thaliana expressing 5'-adenylylsulfate reductase from Pseudomonas aeruginosa.
The Plant journal : for cell and molecular biology.
2002 Dec; 32(6):879-89. doi:
10.1046/j.1365-313x.2002.01477.x. [PMID: 12492831] - Oliver Berkowitz, Markus Wirtz, Alexander Wolf, Jürgen Kuhlmann, Rüdiger Hell. Use of biomolecular interaction analysis to elucidate the regulatory mechanism of the cysteine synthase complex from Arabidopsis thaliana.
The Journal of biological chemistry.
2002 Aug; 277(34):30629-34. doi:
10.1074/jbc.m111632200. [PMID: 12063244] - Alexandra Kutz, Axel Müller, Peter Hennig, Werner M Kaiser, Markus Piotrowski, Elmar W Weiler. A role for nitrilase 3 in the regulation of root morphology in sulphur-starving Arabidopsis thaliana.
The Plant journal : for cell and molecular biology.
2002 Apr; 30(1):95-106. doi:
10.1046/j.1365-313x.2002.01271.x. [PMID: 11967096] - R Jost, O Berkowitz, M Wirtz, L Hopkins, M J Hawkesford, R Hell. Genomic and functional characterization of the oas gene family encoding O-acetylserine (thiol) lyases, enzymes catalyzing the final step in cysteine biosynthesis in Arabidopsis thaliana.
Gene.
2000 Aug; 253(2):237-47. doi:
10.1016/s0378-1119(00)00261-4. [PMID: 10940562] - K Saito. Regulation of sulfate transport and synthesis of sulfur-containing amino acids.
Current opinion in plant biology.
2000 Jun; 3(3):188-95. doi:
. [PMID: 10837270] - A Koprivova, M Suter, R O den Camp, C Brunold, S Kopriva. Regulation of sulfate assimilation by nitrogen in Arabidopsis.
Plant physiology.
2000 Mar; 122(3):737-46. doi:
10.1104/pp.122.3.737. [PMID: 10712537] - H Kim, M Y Hirai, H Hayashi, M Chino, S Naito, T Fujiwara. Role of O-acetyl-l-serine in the coordinated regulation of the expression of a soybean seed storage-protein gene by sulfur and nitrogen nutrition.
Planta.
1999 Sep; 209(3):282-9. doi:
10.1007/s004250050634. [PMID: 10502094] - M Droux, M L Ruffet, R Douce, D Job. Interactions between serine acetyltransferase and O-acetylserine (thiol) lyase in higher plants--structural and kinetic properties of the free and bound enzymes.
European journal of biochemistry.
1998 Jul; 255(1):235-45. doi:
10.1046/j.1432-1327.1998.2550235.x. [PMID: 9692924] - K Saito, H Yokoyama, M Noji, I Murakoshi. Molecular cloning and characterization of a plant serine acetyltransferase playing a regulatory role in cysteine biosynthesis from watermelon.
The Journal of biological chemistry.
1995 Jul; 270(27):16321-6. doi:
10.1074/jbc.270.27.16321. [PMID: 7608200] - H L Fung, S Chong, E Kowaluk, K Hough, M Kakemi. Mechanisms for the pharmacologic interaction of organic nitrates with thiols. Existence of an extracellular pathway for the reversal of nitrate vascular tolerance by N-acetylcysteine.
The Journal of pharmacology and experimental therapeutics.
1988 May; 245(2):524-30. doi:
NULL. [PMID: 3130476] - . .
.
. doi:
. [PMID: 15020643]