CID 3033942 (BioDeep_00000852015)

   


代谢物信息卡片


CID 3033942

化学式: C20H32 (272.2504)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1CC23CCC4C(CC=CC4(C2CCC1C3)C)(C)C
InChI: InChI=1S/C20H32/c1-14-12-20-11-8-16-18(2,3)9-5-10-19(16,4)17(20)7-6-15(14)13-20/h5,10,14-17H,6-9,11-13H2,1-4H3/t14-,15-,16+,17-,19+,20?/m0/s1

描述信息

同义名列表

1 个代谢物同义名

CID 3033942



数据库引用编号

3 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Suzana Tiemi Ivamoto-Suzuki, José Miguel Celedón, Macaire M S Yuen, Cíntia Sorane Good Kitzberger, Douglas Silva Domingues, Jörg Bohlmann, Luiz Filipe Protasio Pereira. Functional Characterization of ent-Copalyl Diphosphate Synthase and Kaurene Synthase Genes from Coffea arabica L. Journal of agricultural and food chemistry. 2023 Oct; ?(?):. doi: 10.1021/acs.jafc.2c09087. [PMID: 37816128]
  • Yuwei Sun, Zhuo Chen, Guangyi Wang, Huajun Lv, Yaping Mao, Ke Ma, Yong Wang. De novo production of versatile oxidized kaurene diterpenes in Escherichia coli. Metabolic engineering. 2022 09; 73(?):201-213. doi: 10.1016/j.ymben.2022.08.001. [PMID: 35934176]
  • Gang Du, Hai-Yan Gong, Ke-Na Feng, Qian-Qian Chen, Yan-Long Yang, Xiao-Li Fu, Shan Lu, Ying Zeng. Diterpene synthases facilitating production of the kaurane skeleton of eriocalyxin B in the medicinal plant Isodon eriocalyx. Phytochemistry. 2019 Feb; 158(?):96-102. doi: 10.1016/j.phytochem.2018.11.015. [PMID: 30496917]
  • Morteza Gholami, Sedigheh Esmaeilzadeh Bahabadi. Kaurene as the major constituent of the essential oils of the narcotic plant, Khat (Catha edulis Forsk). Natural product research. 2019 Jan; 33(1):126-129. doi: 10.1080/14786419.2018.1437424. [PMID: 29436858]
  • Camila de Souza Araújo, Ana Paula de Oliveira, Alan Diego da Conceição Santos, Amanda Leite Guimarães, Naiane Darklei Dos Santos Silva, Mário Adriano Ávila Queiroz, Edigênia Cavalcante da Cruz Araújo, Jackson Roberto Guedes da Silva Almeida. Total content of kaurene diterpenes in Annona vepretorum stems via 1 H qNMR: A method for speeding the identification of bioactive extracts. Phytochemical analysis : PCA. 2019 Jan; 30(1):83-88. doi: 10.1002/pca.2792. [PMID: 30160074]
  • Nicholas D Gold, Elena Fossati, Cecilie Cetti Hansen, Marcos DiFalco, Veronique Douchin, Vincent J J Martin. A Combinatorial Approach To Study Cytochrome P450 Enzymes for De Novo Production of Steviol Glucosides in Baker's Yeast. ACS synthetic biology. 2018 12; 7(12):2918-2929. doi: 10.1021/acssynbio.8b00470. [PMID: 30474973]
  • A M Yáñez-Serrano, L Fasbender, J Kreuzwieser, D Dubbert, S Haberstroh, R Lobo-do-Vale, M C Caldeira, C Werner. Volatile diterpene emission by two Mediterranean Cistaceae shrubs. Scientific reports. 2018 05; 8(1):6855. doi: 10.1038/s41598-018-25056-w. [PMID: 29717178]
  • Katrin Geisler, Niels Berg Jensen, Macaire M S Yuen, Lina Madilao, Jörg Bohlmann. Modularity of Conifer Diterpene Resin Acid Biosynthesis: P450 Enzymes of Different CYP720B Clades Use Alternative Substrates and Converge on the Same Products. Plant physiology. 2016 05; 171(1):152-64. doi: 10.1104/pp.16.00180. [PMID: 26936895]
  • Liang Li, Xi Chen, Chaoyang Ma, Hongqing Wu, Shuting Qi. Piriformospora indica requires kaurene synthase activity for successful plant colonization. Plant physiology and biochemistry : PPB. 2016 May; 102(?):151-60. doi: 10.1016/j.plaphy.2016.02.017. [PMID: 26943021]
  • Mi Jung Kim, Jingjing Jin, Junshi Zheng, Limsoon Wong, Nam-Hai Chua, In-Cheol Jang. Comparative Transcriptomics Unravel Biochemical Specialization of Leaf Tissues of Stevia for Diterpenoid Production. Plant physiology. 2015 Dec; 169(4):2462-80. doi: 10.1104/pp.15.01353. [PMID: 26438788]
  • Celia Bustos-Brito, Mariano Sánchez-Castellanos, Baldomero Esquivel, José S Calderón, Fernando Calzada, Lilian Yépez-Mulia, Pedro Joseph-Nathan, Gabriel Cuevas, Leovigildo Quijano. ent-Kaurene Glycosides from Ageratina cylindrica. Journal of natural products. 2015 Nov; 78(11):2580-7. doi: 10.1021/acs.jnatprod.5b00488. [PMID: 26517282]
  • Xuan Lu, David M Hershey, Li Wang, Adam J Bogdanove, Reuben J Peters. An ent-kaurene-derived diterpenoid virulence factor from Xanthomonas oryzae pv. oryzicola. The New phytologist. 2015 Apr; 206(1):295-302. doi: 10.1111/nph.13187. [PMID: 25406717]
  • Jiahe Wu, Chuanfeng Zhu, Jinhuan Pang, Xiangrong Zhang, Chunlin Yang, Guixian Xia, Yingchuan Tian, Chaozu He. OsLOL1, a C2C2-type zinc finger protein, interacts with OsbZIP58 to promote seed germination through the modulation of gibberellin biosynthesis in Oryza sativa. The Plant journal : for cell and molecular biology. 2014 Dec; 80(6):1118-30. doi: 10.1111/tpj.12714. [PMID: 25353370]
  • Wenting Liu, Xinxin Feng, Yingying Zheng, Chun-Hsiang Huang, Chiaki Nakano, Tsutomu Hoshino, Shannon Bogue, Tzu-Ping Ko, Chun-Chi Chen, Yunfeng Cui, Jian Li, Iren Wang, Shang-Te Danny Hsu, Eric Oldfield, Rey-Ting Guo. Structure, function and inhibition of ent-kaurene synthase from Bradyrhizobium japonicum. Scientific reports. 2014 Oct; 4(?):6214. doi: 10.1038/srep06214. [PMID: 25269599]
  • Sho Miyazaki, Hikaru Toyoshima, Masahiro Natsume, Masatoshi Nakajima, Hiroshi Kawaide. Blue-light irradiation up-regulates the ent-kaurene synthase gene and affects the avoidance response of protonemal growth in Physcomitrella patens. Planta. 2014 Jul; 240(1):117-24. doi: 10.1007/s00425-014-2068-4. [PMID: 24715198]
  • Philipp Zerbe, Angela Chiang, Jörg Bohlmann. Mutational analysis of white spruce (Picea glauca) ent-kaurene synthase (PgKS) reveals common and distinct mechanisms of conifer diterpene synthases of general and specialized metabolism. Phytochemistry. 2012 Feb; 74(?):30-9. doi: 10.1016/j.phytochem.2011.11.004. [PMID: 22177479]
  • Vasiliki Falara, Tariq A Akhtar, Thuong T H Nguyen, Eleni A Spyropoulou, Petra M Bleeker, Ines Schauvinhold, Yuki Matsuba, Megan E Bonini, Anthony L Schilmiller, Robert L Last, Robert C Schuurink, Eran Pichersky. The tomato terpene synthase gene family. Plant physiology. 2011 Oct; 157(2):770-89. doi: 10.1104/pp.111.179648. [PMID: 21813655]
  • Sho Miyazaki, Takumi Katsumata, Masahiro Natsume, Hiroshi Kawaide. The CYP701B1 of Physcomitrella patens is an ent-kaurene oxidase that resists inhibition by uniconazole-P. FEBS letters. 2011 Jun; 585(12):1879-83. doi: 10.1016/j.febslet.2011.04.057. [PMID: 21545802]
  • Yang Wang, Ting Han, Li-Ming Xue, Ping Han, Qiao-Yan Zhang, Bao-Kang Huang, Hong Zhang, Qian-Liang Ming, Wei Peng, Lu-Ping Qin. Hepatotoxicity of kaurene glycosides from Xanthium strumarium L. fruits in mice. Die Pharmazie. 2011 Jun; 66(6):445-9. doi: NULL. [PMID: 21699085]
  • Claudio Pugliesi, Marco Fambrini, Mariangela Salvini. Molecular cloning and expression profile analysis of three sunflower (Helianthus annuus) diterpene synthase genes. Biochemical genetics. 2011 Feb; 49(1-2):46-62. doi: 10.1007/s10528-010-9384-6. [PMID: 20924785]
  • Yoshinori Sugai, Sho Miyazaki, Shinichiro Mukai, Isamu Yumoto, Masahiro Natsume, Hiroshi Kawaide. Enzymatic total synthesis of gibberellin A₄ from acetate. Bioscience, biotechnology, and biochemistry. 2011; 75(1):128-35. doi: 10.1271/bbb.100733. [PMID: 21228464]
  • Lan Ding, Linlin Qi, Hongwei Jing, Juan Li, Wei Wang, Tao Wang. Phytotoxic effects of leukamenin E (an ent-kaurene diterpenoid) on root growth and root hair development in Lactuca sativa L. seedlings. Journal of chemical ecology. 2008 Nov; 34(11):1492-500. doi: 10.1007/s10886-008-9556-6. [PMID: 18937011]
  • Xian Li, Weilie Xiao, Jianxin Pu, Lili Ban, Yunheng Shen, Zhiying Weng, Shenghong Li, Handong Sun. Cytotoxic ent-kaurene diterpenoids from Isodon phyllostachys. Phytochemistry. 2006 Jul; 67(13):1336-40. doi: 10.1016/j.phytochem.2006.05.002. [PMID: 16777159]
  • Minoru Otsuka, Hiromichi Kenmoku, Mikihiro Ogawa, Kazunori Okada, Wataru Mitsuhashi, Takeshi Sassa, Yuji Kamiya, Tomonobu Toyomasu, Shinjiro Yamaguchi. Emission of ent-kaurene, a diterpenoid hydrocarbon precursor for gibberellins, into the headspace from plants. Plant & cell physiology. 2004 Sep; 45(9):1129-38. doi: 10.1093/pcp/pch149. [PMID: 15509835]
  • Fumihiro Nagashima, Masuo Kondoh, Masaki Kawase, Siro Simizu, Hiroyuki Osada, Makiko Fujii, Yoshiteru Watanabe, Masao Sato, Yoshinori Asakawa. [Apoptosis-inducing properties of ent-kaurene-type diterpenoids from the liverwort Jungermannia truncata]. Planta medica. 2003 Apr; 69(4):377-9. doi: 10.1055/s-2003-38888. [PMID: 12709910]
  • L I Somova, F O Shode, K Moodley, Y Govender. Cardiovascular and diuretic activity of kaurene derivatives of Xylopia aethiopica and Alepidea amatymbica. Journal of ethnopharmacology. 2001 Oct; 77(2-3):165-74. doi: 10.1016/s0378-8741(01)00285-9. [PMID: 11535360]
  • C A Helliwell, A Poole, W J Peacock, E S Dennis. Arabidopsis ent-kaurene oxidase catalyzes three steps of gibberellin biosynthesis. Plant physiology. 1999 Feb; 119(2):507-10. doi: 10.1104/pp.119.2.507. [PMID: 9952446]
  • H Kawaide, R Imai, T Sassa, Y Kamiya. Ent-kaurene synthase from the fungus Phaeosphaeria sp. L487. cDNA isolation, characterization, and bacterial expression of a bifunctional diterpene cyclase in fungal gibberellin biosynthesis. The Journal of biological chemistry. 1997 Aug; 272(35):21706-12. doi: 10.1074/jbc.272.35.21706. [PMID: 9268298]
  • J C Jennings, J A Banks, R C Coolbaugh. Subtractive hybridization between cDNAs from untreated and AMO-1618-treated cultures of Gibberella fujikuroi. Plant & cell physiology. 1996 Sep; 37(6):847-54. doi: 10.1093/oxfordjournals.pcp.a029021. [PMID: 8888622]
  • R J Bensen, G S Johal, V C Crane, J T Tossberg, P S Schnable, R B Meeley, S P Briggs. Cloning and characterization of the maize An1 gene. The Plant cell. 1995 Jan; 7(1):75-84. doi: 10.1105/tpc.7.1.75. [PMID: 7696880]
  • J A Zeevaart, D A Gage. ent-kaurene biosynthesis is enhanced by long photoperiods in the long-day plants Spinacia oleracea L. and Agrostemma githago L. Plant physiology. 1993 Jan; 101(1):25-9. doi: 10.1104/pp.101.1.25. [PMID: 8278497]
  • P J Ashman, A Mackenzie, P M Bramley. Characterization of ent-kaurene oxidase activity from Gibberella fujikuroi. Biochimica et biophysica acta. 1990 Nov; 1036(2):151-7. doi: 10.1016/0304-4165(90)90027-t. [PMID: 2223832]