(3R)-3-(7-amino-3-oxo-1H-isoindol-2-yl)piperidine-2,6-dione (BioDeep_00000849673)
代谢物信息卡片
(3R)-3-(7-amino-3-oxo-1H-isoindol-2-yl)piperidine-2,6-dione
化学式: C13H13N3O3 (259.0956868)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1CC(=O)NC(=O)C1N2CC3=C(C2=O)C=CC=C3N
InChI: InChI=1S/C13H13N3O3/c14-9-3-1-2-7-8(9)6-16(13(7)19)10-4-5-11(17)15-12(10)18/h1-3,10H,4-6,14H2,(H,15,17,18)/t10-/m1/s1
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代谢反应
0 个相关的代谢反应过程信息。
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在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
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文献列表
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Leukemia.
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Blood.
2011 Nov; 118(19):5119-25. doi:
10.1182/blood-2011-07-362475. [PMID: 21937701] - Eric Moumas, William Hanf, Estelle Desport, Julie Abraham, Sébastien Delbès, Céline Debiais, Laurence Lacotte-Thierry, Guy Touchard, Arnaud Jaccard, Jean-Paul Fermand, Frank Bridoux. [New insights in the treatment of myeloma with renal failure].
Nephrologie & therapeutique.
2011 Nov; 7(6):457-66. doi:
10.1016/j.nephro.2011.03.002. [PMID: 21515102] - Keiichi Tozawa, Morihiko Sagawa, Masahiro Kizaki. Quinone methide tripterine, celastrol, induces apoptosis in human myeloma cells via NF-κB pathway.
International journal of oncology.
2011 Nov; 39(5):1117-22. doi:
10.3892/ijo.2011.1161. [PMID: 21850367] - Estelle Desport, Eric Moumas, Julie Abraham, Sébastien Delbès, Laurence Lacotte-Thierry, Guy Touchard, Jean-Paul Fermand, Frank Bridoux, Arnaud Jaccard. [Current treatment of AL amyloidosis].
Nephrologie & therapeutique.
2011 Nov; 7(6):467-73. doi:
10.1016/j.nephro.2011.02.003. [PMID: 21497573] - Antonio Coppola, Antonella Tufano, Mirko Di Capua, Massimo Franchini. Bleeding and thrombosis in multiple myeloma and related plasma cell disorders.
Seminars in thrombosis and hemostasis.
2011 Nov; 37(8):929-45. doi:
10.1055/s-0031-1297372. [PMID: 22198858] - Martin W Hoyle, William Henley. Improved curve fits to summary survival data: application to economic evaluation of health technologies.
BMC medical research methodology.
2011 Oct; 11(?):139. doi:
10.1186/1471-2288-11-139. [PMID: 21985358] - Marek Hus, Norbert Grzasko, Marta Szostek, Andrzej Pluta, Grzegorz Helbig, Dariusz Woszczyk, Maria Adamczyk-Cioch, Dariusz Jawniak, Wojciech Legiec, Marta Morawska, Justyna Kozinska, Piotr Waciński, Anna Dmoszynska. Thalidomide, dexamethasone and lovastatin with autologous stem cell transplantation as a salvage immunomodulatory therapy in patients with relapsed and refractory multiple myeloma.
Annals of hematology.
2011 Oct; 90(10):1161-6. doi:
10.1007/s00277-011-1276-2. [PMID: 21698395] - S Sharma, C Rana, P B Vinod, A Gupta. Plasma cell myeloma in a renal transplant recipient: A case report and review of literature.
Indian journal of nephrology.
2011 Oct; 21(4):270-2. doi:
10.4103/0971-4065.78074. [PMID: 22022088] - Taiga Nishihori, Melissa Alsina. Advances in the autologous and allogeneic transplantation strategies for multiple myeloma.
Cancer control : journal of the Moffitt Cancer Center.
2011 Oct; 18(4):258-67. doi:
10.1177/107327481101800406. [PMID: 21976244] - Flora Zagouri, Maria Roussou, Efstathios Kastritis, Andreas Koureas, Eleni Tsokou, Magdalini Migkou, Maria Gavriatopoulou, Nikitas Nikitas, Maria Gkotzamanidou, Evangelos Terpos, Meletios-Athanasios Dimopoulos. Lenalidomide-associated pneumonitis in patients with plasma cell dyscrasias.
American journal of hematology.
2011 Oct; 86(10):882-4. doi:
10.1002/ajh.22135. [PMID: 21818766] - Xavier C Badoux, Michael J Keating, Sijin Wen, Bang-Ning Lee, Mariela Sivina, James Reuben, William G Wierda, Susan M O'Brien, Stefan Faderl, Steven M Kornblau, Jan A Burger, Alessandra Ferrajoli. Lenalidomide as initial therapy of elderly patients with chronic lymphocytic leukemia.
Blood.
2011 Sep; 118(13):3489-98. doi:
10.1182/blood-2011-03-339077. [PMID: 21725050] - Craig C Hofmeister, Xiaoxia Yang, Flavia Pichiorri, Ping Chen, Darlene M Rozewski, Amy J Johnson, Seungsoo Lee, Zhongfa Liu, Celia L Garr, Erinn M Hade, Jia Ji, Larry J Schaaf, Don M Benson, Eric H Kraut, William J Hicks, Kenneth K Chan, Ching-Shih Chen, Sherif S Farag, Michael R Grever, John C Byrd, Mitch A Phelps. Phase I trial of lenalidomide and CCI-779 in patients with relapsed multiple myeloma: evidence for lenalidomide-CCI-779 interaction via P-glycoprotein.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2011 Sep; 29(25):3427-34. doi:
10.1200/jco.2010.32.4962. [PMID: 21825263] - Pranjal K Boruah, Scott Bolesta, Shubhra M Shetty. Possible lenalidomide-induced Stevens-Johnson syndrome during treatment for multiple myeloma.
Pharmacotherapy.
2011 Sep; 31(9):925. doi:
10.1592/phco.31.9.925. [PMID: 21923596] - Brigitte Neuber, Isabelle Herth, Claudia Tolliver, Stefan Schoenland, Ute Hegenbart, Dirk Hose, Mathias Witzens-Harig, Anthony D Ho, Hartmut Goldschmidt, Bernard Klein, Michael Hundemer. Lenalidomide enhances antigen-specific activity and decreases CD45RA expression of T cells from patients with multiple myeloma.
Journal of immunology (Baltimore, Md. : 1950).
2011 Jul; 187(2):1047-56. doi:
10.4049/jimmunol.1002460. [PMID: 21677134] - Hillard M Lazarus, Scott R Sommers, Lisa M Arfons, Pingfu Fu, S A Ataergin, N M Kaye, F Liu, Tamila L Kindwall-Keller, Brenda W Cooper, Mary J Laughlin, Richard J Creger, Paul M Barr, Stanton L Gerson, David Kaplan. Spontaneous autologous graft-versus-host disease in plasma cell myeloma autograft recipients: flow cytometric analysis of hematopoietic progenitor cell grafts.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.
2011 Jul; 17(7):970-8. doi:
10.1016/j.bbmt.2011.03.005. [PMID: 21440080] - Angela Dispenzieri. POEMS syndrome: 2011 update on diagnosis, risk-stratification, and management.
American journal of hematology.
2011 Jul; 86(7):591-601. doi:
10.1002/ajh.22050. [PMID: 21681783] - P Kapoor, S Kumar, S J Mandrekar, K M Laumann, A Dispenzieri, M Q Lacy, D Dingli, M A Gertz, R A Kyle, P R Greipp, S V Rajkumar, T E Witzig. Efficacy of thalidomide- or lenalidomide-based therapy in proliferative multiple myeloma.
Leukemia.
2011 Jul; 25(7):1195-7. doi:
10.1038/leu.2011.54. [PMID: 21468037] - Benedetto Bruno, Francesca Gay, Mario Boccadoro, Antonio Palumbo. Management of myeloma: an Italian perspective.
Clinical lymphoma, myeloma & leukemia.
2011 Jun; 11 Suppl 1(?):S82-6. doi:
10.1016/j.clml.2011.03.026. [PMID: 22035755] - Martha Q Lacy. New immunomodulatory drugs in myeloma.
Current hematologic malignancy reports.
2011 Jun; 6(2):120-5. doi:
10.1007/s11899-011-0077-y. [PMID: 21327565] - Ron C Gaba, John P Kenny, Pawan Gundavaram, Jeremy R Katz, Liza R Aquino Escuadro, Sujata Gaitonde. Subcutaneous plasmacytoma metastasis precipitated by tunneled central venous catheter insertion.
Case reports in oncology.
2011 May; 4(2):315-22. doi:
10.1159/000330044. [PMID: 21738502] - Chad C Bjorklund, Wencai Ma, Zhi-Qiang Wang, R Eric Davis, Deborah J Kuhn, Steven M Kornblau, Michael Wang, Jatin J Shah, Robert Z Orlowski. Evidence of a role for activation of Wnt/beta-catenin signaling in the resistance of plasma cells to lenalidomide.
The Journal of biological chemistry.
2011 Apr; 286(13):11009-20. doi:
10.1074/jbc.m110.180208. [PMID: 21189262] - Ulrike Klein, Kai Neben, Thomas Hielscher, Christiane Heiss, Anthony D Ho, Hartmut Goldschmidt. Lenalidomide in combination with dexamethasone: effective regimen in patients with relapsed or refractory multiple myeloma complicated by renal impairment.
Annals of hematology.
2011 Apr; 90(4):429-39. doi:
10.1007/s00277-010-1080-4. [PMID: 20857112] - Karthik Ramasamy, Shameem Mahmood, Ziyi Lim, Sophie Corderoy, Stephen Devereux, Ghulam J Mufti, Antonio Pagliuca, Stephen Schey. Alemtuzumab-based reduced-intensity conditioning allogeneic transplantation for myeloma and plasma cell leukemia - a single-institution experience.
Clinical lymphoma, myeloma & leukemia.
2011 Apr; 11(2):242-5. doi:
10.1016/j.clml.2011.03.004. [PMID: 21575930] - Rajendra Prasad, Sanjay Kumar Verma, Rakhi Sodhi. Multiple myeloma with lung plasmacytoma.
Lung India : official organ of Indian Chest Society.
2011 Apr; 28(2):136-8. doi:
10.4103/0970-2113.80331. [PMID: 21712927] - Richard Specter, Vaishali Sanchorawala, David C Seldin, Anthony Shelton, Salli Fennessey, Kathleen T Finn, Jerome B Zeldis, Laura M Dember. Kidney dysfunction during lenalidomide treatment for AL amyloidosis.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
2011 Mar; 26(3):881-6. doi:
10.1093/ndt/gfq482. [PMID: 20693160] - Ernesto Pérez Persona, Mercedes Gironella Mesa, Pedro José García Sánchez, Ana Pilar González Rodríguez. Lenalidomide treatment for patients with multiple myeloma: diagnosis and management of most frequent adverse events.
Advances in therapy.
2011 Mar; 28 Suppl 1(?):11-6. doi:
10.1007/s12325-010-0102-x. [PMID: 21431627] - Soo-Young Bae, Jae-Sook Ahn, Deok-Hwan Yang, Yeo-Kyeoung Kim, Jung-Joon Min, Ho-Chun Song, Hee-Seung Bom, Yong Yeon Jeong, Hyeoung-Joon Kim, Je-Jung Lee. A Case of Disseminated and Fulminant Plasmacytomas That Developed during Bortezomib Treatment.
Case reports in oncology.
2011 Feb; 4(1):101-5. doi:
10.1159/000324920. [PMID: 21475598] - Katherine E Warren, Stewart Goldman, Ian F Pollack, Jason Fangusaro, Paula Schaiquevich, Clinton F Stewart, Dana Wallace, Susan M Blaney, Roger Packer, Tobey Macdonald, Regina Jakacki, James M Boyett, Larry E Kun. Phase I trial of lenalidomide in pediatric patients with recurrent, refractory, or progressive primary CNS tumors: Pediatric Brain Tumor Consortium study PBTC-018.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2011 Jan; 29(3):324-9. doi:
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Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer.
2011; 183(?):3-23. doi:
10.1007/978-3-540-85772-3_1. [PMID: 21509678] - Stephanie Stringer, Kolitha Basnayake, Colin Hutchison, Paul Cockwell. Recent advances in the pathogenesis and management of cast nephropathy (myeloma kidney).
Bone marrow research.
2011; 2011(?):493697. doi:
10.1155/2011/493697. [PMID: 22046563] - Amir Sharabi, Nechama Haran-Ghera. Immune recovery after cyclophosphamide treatment in multiple myeloma: implication for maintenance immunotherapy.
Bone marrow research.
2011; 2011(?):269519. doi:
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PloS one.
2011; 6(11):e27707. doi:
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