Methionyl-leucyl-phenylalanine (BioDeep_00000848917)
代谢物信息卡片
Methionyl-leucyl-phenylalanine
化学式: C20H31N3O4S (409.20351660000006)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(C)CC(C(=O)NC(CC1=CC=CC=C1)C(=O)O)NC(=O)C(CCSC)N
InChI: InChI=1S/C20H31N3O4S/c1-13(2)11-16(22-18(24)15(21)9-10-28-3)19(25)23-17(20(26)27)12-14-7-5-4-6-8-14/h4-8,13,15-17H,9-12,21H2,1-3H3,(H,22,24)(H,23,25)(H,26,27)/t15-,16-,17-/m0/s1
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
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0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Igor A Schepetkin, Svetlana V Kushnarenko, Gulmira Özek, Liliya N Kirpotina, Pritam Sinharoy, Gulzhakhan A Utegenova, Karime T Abidkulova, Temel Özek, Kemal Hüsnü Can Başer, Anastasia R Kovrizhina, Andrei I Khlebnikov, Derek S Damron, Mark T Quinn. Modulation of Human Neutrophil Responses by the Essential Oils from Ferula akitschkensis and Their Constituents.
Journal of agricultural and food chemistry.
2016 Sep; 64(38):7156-70. doi:
10.1021/acs.jafc.6b03205. [PMID: 27586050] - Li-Chai Chen, Hsiang-Ruei Liao, Pei-Yu Chen, Wen-Lung Kuo, Tsung-Hsien Chang, Ping-Jyun Sung, Zhi-Hong Wen, Jih-Jung Chen. Limonoids from the Seeds of Swietenia macrophylla and Their Anti-Inflammatory Activities.
Molecules (Basel, Switzerland).
2015 Oct; 20(10):18551-64. doi:
10.3390/molecules201018551. [PMID: 26473818] - Jih-Jung Chen, Chieh-Kai Yang, Yueh-Hsiung Kuo, Tsong-Long Hwang, Wen-Lung Kuo, Yun-Ping Lim, Ping-Jyun Sung, Tsung-Hsien Chang, Ming-Jen Cheng. New Coumarin Derivatives and Other Constituents from the Stem Bark of Zanthoxylum avicennae: Effects on Neutrophil Pro-Inflammatory Responses.
International journal of molecular sciences.
2015 Apr; 16(5):9719-31. doi:
10.3390/ijms16059719. [PMID: 25938967] - Izabela Burzynska-Pedziwiatr, Malgorzata Bukowiecka-Matusiak, Marzena Wojcik, Waldemar Machala, Malgorzata Bienkiewicz, Grzegorz Spolnik, Witold Danikiewicz, Lucyna Alicja Wozniak. Dual stimulus-dependent effect of Oenothera paradoxa extract on the respiratory burst in human leukocytes: suppressing for Escherichia coli and phorbol myristate acetate and stimulating for formyl-methionyl-leucyl-phenylalanine.
Oxidative medicine and cellular longevity.
2014; 2014(?):764367. doi:
10.1155/2014/764367. [PMID: 25298860] - Laurent Camous, Lubka Roumenina, Sylvain Bigot, Soumeya Brachemi, Véronique Frémeaux-Bacchi, Philippe Lesavre, Lise Halbwachs-Mecarelli. Complement alternative pathway acts as a positive feedback amplification of neutrophil activation.
Blood.
2011 Jan; 117(4):1340-9. doi:
10.1182/blood-2010-05-283564. [PMID: 21063021] - Gerritje J W van der Windt, W Joost Wiersinga, Catharina W Wieland, Ivo C S I Tjia, Nicholas P Day, Sharon J Peacock, Sandrine Florquin, Tom van der Poll. Osteopontin impairs host defense during established gram-negative sepsis caused by Burkholderia pseudomallei (melioidosis).
PLoS neglected tropical diseases.
2010 Aug; 4(8):. doi:
10.1371/journal.pntd.0000806. [PMID: 20824216] - Neil Dufton, Robert Hannon, Vincenzo Brancaleone, Jesmond Dalli, Hetal B Patel, Mohini Gray, Fulvio D'Acquisto, Julia C Buckingham, Mauro Perretti, Roderick J Flower. Anti-inflammatory role of the murine formyl-peptide receptor 2: ligand-specific effects on leukocyte responses and experimental inflammation.
Journal of immunology (Baltimore, Md. : 1950).
2010 Mar; 184(5):2611-2619. doi:
10.4049/jimmunol.0903526. [PMID: 20107188] - Christina Rappel, Dirk Schaumlöffel. Absolute peptide quantification by lutetium labeling and nanoHPLC-ICPMS with isotope dilution analysis.
Analytical chemistry.
2009 Jan; 81(1):385-93. doi:
10.1021/ac801814a. [PMID: 19117464] - J G Filep, A Fournier, E Földes-Filep. Acute pro-inflammatory actions of endothelin-1 in the guinea-pig lung: involvement of ETA and ETB receptors.
British journal of pharmacology.
1995 May; 115(2):227-36. doi:
10.1111/j.1476-5381.1995.tb15868.x. [PMID: 7670725] - R Obrist, J Schmidli, R Müller, H Gallati, J P Obrecht. Acute and subacute toxicity of chemotactic conjugates between monoclonal antibody and fMet-Leu-Phe in humans: a phase I clinical trial.
Cancer immunology, immunotherapy : CII.
1991; 32(6):406-8. doi:
10.1007/bf01741336. [PMID: 2007248] - S Pontremoli, E Melloni, B Sparatore, M Michetti, F Salamino, B L Horecker. Isozymes of protein kinase C in human neutrophils and their modification by two endogenous proteinases.
The Journal of biological chemistry.
1990 Jan; 265(2):706-12. doi:
10.1016/s0021-9258(19)40107-5. [PMID: 2295614] - J E Pennington, B Kemmerich, P H Kazanjian, J D Marsh, L W Boerth. Verapamil impairs human neutrophil chemotaxis by a non-calcium-mediated mechanism.
The Journal of laboratory and clinical medicine.
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