3-Desacetylvecuronium (BioDeep_00000848796)
代谢物信息卡片
化学式: C32H55N2O3+ (515.421246)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(=O)OC1C(CC2C1(CCC3C2CCC4C3(CC(C(C4)O)N5CCCCC5)C)C)[N+]6(CCCCC6)C
InChI: InChI=1S/C32H55N2O3/c1-22(35)37-30-28(34(4)17-9-6-10-18-34)20-26-24-12-11-23-19-29(36)27(33-15-7-5-8-16-33)21-32(23,3)25(24)13-14-31(26,30)2/h23-30,36H,5-21H2,1-4H3/q+1/t23-,24+,25-,26-,27-,28-,29-,30-,31-,32-/m0/s1
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
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Plant Reactome(0)
INOH(0)
PlantCyc(0)
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0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Shawn P Vorce, Craig T Mallak, Aaron Jacobs. Quantitative analysis of the aminosteroidal non-depolarizing neuromuscular blocking agent vecuronium by LC-ESI-MS: A Postmortem Investigation.
Journal of analytical toxicology.
2008 Jul; 32(6):422-7. doi:
10.1093/jat/32.6.422. [PMID: 18652748] - Peter M C Wright, Gerald McCarthy, Janos Szenohradszky, Manohar L Sharma, James E Caldwell. Influence of chronic phenytoin administration on the pharmacokinetics and pharmacodynamics of vecuronium.
Anesthesiology.
2004 Mar; 100(3):626-33. doi:
10.1097/00000542-200403000-00024. [PMID: 15108978] - S Schiere, J H Proost, M Schuringa, J M Wierda. Pharmacokinetics and pharmacokinetic-dynamic relationship between rapacuronium (Org 9487) and its 3-desacetyl metabolite (Org 9488).
Anesthesia and analgesia.
1999 Mar; 88(3):640-7. doi:
10.1097/00000539-199903000-00032. [PMID: 10072020] - K Kurahashi, H Maruta. The effect of sevoflurane and isoflurane on the neuromuscular block produced by vecuronium continuous infusion.
Anesthesia and analgesia.
1996 May; 82(5):942-7. doi:
10.1097/00000539-199605000-00009. [PMID: 8610903] - J E Caldwell, J Szenohradszky, V Segredo, P M Wright, C McLoughlin, M L Sharma, L D Gruenke, D M Fisher, R D Miller. The pharmacodynamics and pharmacokinetics of the metabolite 3-desacetylvecuronium (ORG 7268) and its parent compound, vecuronium, in human volunteers.
The Journal of pharmacology and experimental therapeutics.
1994 Sep; 270(3):1216-22. doi:
NULL. [PMID: 7932174] - V Segredo, J E Caldwell, M A Matthay, M L Sharma, L D Gruenke, R D Miller. Persistent paralysis in critically ill patients after long-term administration of vecuronium.
The New England journal of medicine.
1992 Aug; 327(8):524-8. doi:
10.1056/nejm199208203270804. [PMID: 1353252] - J Ducharme, F Varin, D R Bevan, F Donati, Y Théorêt. High-performance liquid chromatography-electrochemical detection of vecuronium and its metabolites in human plasma.
Journal of chromatography.
1992 Jan; 573(1):79-86. doi:
10.1016/0378-4347(92)80477-8. [PMID: 1348748] - V Segredo, Y S Shin, M L Sharma, L D Gruenke, J E Caldwell, K S Khuenl-Brady, S Agoston, R D Miller. Pharmacokinetics, neuromuscular effects, and biodisposition of 3-desacetylvecuronium (Org 7268) in cats.
Anesthesiology.
1991 Jun; 74(6):1052-9. doi:
10.1097/00000542-199106000-00013. [PMID: 1675040] - T Furuta, P C Canfell, K P Castagnoli, M L Sharma, R D Miller. Quantitation of pancuronium, 3-desacetylpancuronium, vecuronium, 3-desacetylvecuronium, pipecuronium and 3-desacetylpipecuronium in biological fluids by capillary gas chromatography using nitrogen-sensitive detection.
Journal of chromatography.
1988 May; 427(1):41-53. doi:
10.1016/0378-4347(88)80103-8. [PMID: 2900840]