tirucallane (BioDeep_00000848699)
代谢物信息卡片
tirucallane
化学式: C30H54 (414.4225)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(C)CCCC(C)C1CCC2(C1(CCC3C2CCC4C3(CCCC4(C)C)C)C)C
InChI: InChI=1S/C30H54/c1-21(2)11-9-12-22(3)23-15-19-30(8)25-13-14-26-27(4,5)17-10-18-28(26,6)24(25)16-20-29(23,30)7/h21-26H,9-20H2,1-8H3/t22-,23-,24-,25+,26-,28+,29-,30+/m0/s1
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Ling Chuang, Shenyu Liu, Jakob Franke. Post-Cyclization Skeletal Rearrangements in Plant Triterpenoid Biosynthesis by a Pair of Branchpoint Isomerases.
Journal of the American Chemical Society.
2023 03; 145(9):5083-5091. doi:
10.1021/jacs.2c10838. [PMID: 36821810] - Bingyang Zhang, Di Liu, Shijie Cao, Tie Yao, Guanke Liu, Liyi Chen, Feng Qiu. Anti-proliferative tirucallane triterpenoids from gum resin of Boswellia sacra.
Bioorganic chemistry.
2022 Dec; 129(?):106155. doi:
10.1016/j.bioorg.2022.106155. [PMID: 36209562] - Stephen S Chang, Hung-Tse Huang, Yu-Chi Lin, Chih-Hua Chao, Geng-You Liao, Zhi-Hu Lin, Hui-Chi Huang, Jenny Chun-Ling Kuo, Chia-Ching Liaw, Chen-Jei Tai, Yao-Haur Kuo. Neritriterpenols A-G, euphane and tirucallane triterpenes from Euphorbia neriifolia L. and their bioactivity.
Phytochemistry.
2022 Jul; 199(?):113199. doi:
10.1016/j.phytochem.2022.113199. [PMID: 35427651] - Jean Baptiste Sokoudjou, Cyrille Ngoufack Tagousop, Afsar Khan, Siméon Pierre Chegaing Fodouop, Serge Secco Atsafack, Norbert Kodjio, Olubunmi Atolani, Donatien Gatsing. Canarimoic acid: new tirucallane triterpene with antisalmonellal activity from the stem bark of Canarium schweinfurthii Engl.
Natural product research.
2022 May; 36(9):2363-2369. doi:
10.1080/14786419.2020.1836628. [PMID: 33107336] - Bosco Peron Leutcha, Denis Kehdinga Sema, Jean Paul Dzoyem, Godfred Aponglen Ayimele, Kennedy D Nyongbela, Florence Delie, Éric Alléman, Norbert Sewald, Alain Meli Lannang. Cytotoxicity of a new tirucallane derivative isolated from Stereospermum acuminatissimum K. Schum stem bark.
Natural product research.
2021 Nov; 35(22):4417-4422. doi:
10.1080/14786419.2020.1723085. [PMID: 32011174] - Fang-Shen Liu, Ting-Ting Zhang, Jun Xu, Qin-Xue Jing, Chi Gong, Bang-Jian Dong, Da-Hong Li, Xiao-Qiu Liu, Zhan-Lin Li, Zhong Yuan, Hui-Ming Hua. New tirucallane-type triterpenoids from the resin of Boswellia carteriiand their NO inhibitory activities.
Chinese journal of natural medicines.
2021 Sep; 19(9):686-692. doi:
10.1016/s1875-5364(21)60099-7. [PMID: 34561080] - Nattawut Suchaichit, Kwanjai Kanokmedhakul, Trinop Promgool, Panawan Moosophon, Apiwat Chompoosor, Natcha P Suchaichit, Somdej Kanokmedhakul. A new antibacterial tirucallane from Walsura trichostemon roots.
Natural product research.
2021 Aug; 35(16):2799-2803. doi:
10.1080/14786419.2019.1669025. [PMID: 31544521] - Pei-Yuan Yang, Peng Zhao, Ming Bai, Xiao-Qi Yu, Hui Ren, Qing-Bo Liu, Bin Lin, Shao-Jiang Song, Xiao-Xiao Huang. Structure elucidation and absolute configuration determination of C26, C27 and C30 tirucallane triterpenoids from the leaves of Picrasma quassioides (D. Don) Benn.
Phytochemistry.
2021 Apr; 184(?):112675. doi:
10.1016/j.phytochem.2021.112675. [PMID: 33548770] - Wei Liu, Jie Gao, Miaomiao Li, Haji Akber Aisa, Tao Yuan. Tirucallane triterpenoids from the mastic (Pistacia lentiscus) and their anti-inflammatory and cytotoxic activities.
Phytochemistry.
2021 Feb; 182(?):112596. doi:
10.1016/j.phytochem.2020.112596. [PMID: 33321444] - Ling Zhang, Jianjun Xia, Yanqing Duan, Keyi Wei, Rui Gao, Dasan Li, Xiaomin Liu, Tiandong Zhang, Minghua Qiu. Toonamicrocarpavarin, a new tirucallane-type triterpenoid from Toona Ciliata.
Natural product research.
2021 Jan; 35(2):266-271. doi:
10.1080/14786419.2019.1627351. [PMID: 31305146] - Sheng-Xiang Yang, Cheng-Gang Song, Yi Kuang, Bing Liu, Yan-Xin Zhang, Ming-Zhe Zhang, Chun-Ying Zhang, Gang Ding, Jian-Chun Qin. Cytotoxic Activity of Inositol Angelates and Tirucallane-Type Alkaloids from Amoora Dasyclada.
Molecules (Basel, Switzerland).
2020 Mar; 25(5):. doi:
10.3390/molecules25051222. [PMID: 32182779] - Jie Zhang, Chuan-Xi Wang, Xiao-Jun Song, Shuang Li, Huan Zhao, Guo-Dong Chen, Dan Hu, Hao Gao, Xin-Sheng Yao. A pair of new tirucallane triterpenoid epimers from the stems of Picrasma quassioides.
Chinese journal of natural medicines.
2019 Dec; 17(12):906-911. doi:
10.1016/s1875-5364(19)30111-6. [PMID: 31882044] - Wen-Yu Zhao, Jing-Jie Chen, Chun-Xin Zou, Ying-Ying Zhang, Guo-Dong Yao, Xiao-Bo Wang, Xiao-Xiao Huang, Bin Lin, Shao-Jiang Song. New tirucallane triterpenoids from Picrasma quassioides with their potential antiproliferative activities on hepatoma cells.
Bioorganic chemistry.
2019 03; 84(?):309-318. doi:
10.1016/j.bioorg.2018.11.049. [PMID: 30530072] - Zhong-Ping Jiang, Zhi-Lin Luan, Ruo-Xi Liu, Qun Zhang, Xiao-Chi Ma, Li Shen, Jun Wu. Mangrove Tirucallane- and Apotirucallane-Type Triterpenoids: Structure Diversity of the C-17 Side-Chain and Natural Agonists of Human Farnesoid/Pregnane⁻X⁻Receptor.
Marine drugs.
2018 Dec; 16(12):. doi:
10.3390/md16120488. [PMID: 30563240] - Seoung Rak Lee, Eunyong Choi, Se Hun Jeon, Xue Yan Zhi, Jae Sik Yu, Seon-Hee Kim, Jeongmi Lee, Ki-Moon Park, Ki Hyun Kim. Tirucallane Triterpenoids from the Stems and Stem Bark of Cornus walteri that Control Adipocyte and Osteoblast Differentiations.
Molecules (Basel, Switzerland).
2018 Oct; 23(11):. doi:
10.3390/molecules23112732. [PMID: 30360474] - Vanessa Hernandez, Marinella De Leo, Roberta Cotugno, Alessandra Braca, Nunziatina De Tommasi, Lorella Severino. New Tirucallane-Type Triterpenoids from Guarea guidonia.
Planta medica.
2018 Jul; 84(9-10):716-720. doi:
10.1055/s-0044-100524. [PMID: 29341030] - Ya-Lin Hu, Yi Li, Lu Qiu, Jun-He Li, Li Heng, Shan-Shan Wei, Hong-Liang Gao, Xiao-Bing Wang, Jun Luo, Ling-Yi Kong. New triterpenoids with diverse side-chains from the barks of Melia Toosendan.
Fitoterapia.
2018 Jun; 127(?):62-68. doi:
10.1016/j.fitote.2018.01.011. [PMID: 29391169] - Gervais Mouthé Happi, Ferdinand Mouafo Talontsi, Hartmut Laatsch, Sebastian Zühlke, Bonaventure Tchaleu Ngadjui, Michael Spiteller, Simeon Fogue Kouam. seco-Tiaminic acids B and C: Identification of two novel 3,4-seco-tirucallane triterpenoids isolated from the root of Entandrophragma congoënse (Meliaceae).
Fitoterapia.
2018 Jan; 124(?):17-22. doi:
10.1016/j.fitote.2017.10.004. [PMID: 28987553] - Xu Wang, Jing Zhang, Ya-Qun Li, Bao-Xiang Du, Qi-Hui Sun, Yun-Jiao Cao, Hai-Qiang Jiang, Yu-Hong Liu, Hong-Lei Zhou, Rong Rong. Nortirucallane A, a new tirucallane-type nortriterpenoid isolated from Lonicerae japonicae flos.
Natural product research.
2017 Oct; 31(19):2250-2255. doi:
10.1080/14786419.2017.1299731. [PMID: 28281370] - Yu-Hai Zou, Wen-Ting Liu, Jin-Xia Zhang, Ding-Cheng Xiang. Triterpenoids from the bark of Dysoxylum hainanense and their anti-inflammatory and radical scavenging activity.
Fitoterapia.
2017 Sep; 121(?):159-163. doi:
10.1016/j.fitote.2017.07.012. [PMID: 28739177] - Lawrence Onyango Arot Manguro, Samuel Otieno Wagai. Ursane and tirucallane-type triterpenes of Boswellia rivae oleo-gum resin.
Journal of Asian natural products research.
2016 Sep; 18(9):854-64. doi:
10.1080/10286020.2016.1165674. [PMID: 27049028] - Chen Yan, Yun-Dong Zhang, Xing-Hui Wang, Shun-Dong Geng, Tian-Yuan Wang, Mao Sun, Wei Liang, Wei-Qing Zhang, Xiao-Dong Zhang, Heng Luo. Tirucallane-type triterpenoids from the fruits of Phellodendron chinense Schneid and their cytotoxic activities.
Fitoterapia.
2016 Sep; 113(?):132-8. doi:
10.1016/j.fitote.2016.07.020. [PMID: 27491752] - Jing Tang, Jian Xu, Jie Zhang, Wen-Yuan Liu, Ning Xie, Lei Chen, Feng Feng, Wei Qu. Novel tirucallane triterpenoids from the stem bark of Toona sinensis.
Fitoterapia.
2016 Jul; 112(?):97-103. doi:
10.1016/j.fitote.2016.05.009. [PMID: 27215130] - Yong-Jin Yang, Juan Yao, Xiao-Jie Jin, Zhuan-Ning Shi, Tian-Fei Shen, Jian-Guo Fang, Xiao-Jun Yao, Ying Zhu. Sesquiterpenoids and tirucallane triterpenoids from the roots of Scorzonera divaricata.
Phytochemistry.
2016 Apr; 124(?):86-98. doi:
10.1016/j.phytochem.2016.01.015. [PMID: 26832425] - Yan-Gai Wang, Qin-Ge Ma, Jin Tian, Jin Ren, Ai-Guo Wang, Teng-Fei Ji, Jian-Bo Yang, Ya-Lun Su. Hepatoprotective triterpenes from the gum resin of Boswellia carterii.
Fitoterapia.
2016 Mar; 109(?):266-73. doi:
10.1016/j.fitote.2015.12.018. [PMID: 26739386] - Shuyun Wang, Honggang Liang, Yuqian Zhao, Guihua Wang, Hong Yao, Rena Kasimu, Zhaohua Wu, Yan Li, Jian Huang, Jinhui Wang. New triterpenoids from the latex of Euphorbia resinifera Berg.
Fitoterapia.
2016 Jan; 108(?):33-40. doi:
10.1016/j.fitote.2015.11.009. [PMID: 26586618] - Evelyn Afua Mireku, Souvik Kusari, Dennis Eckelmann, Abraham Yeboah Mensah, Ferdinand M Talontsi, Michael Spiteller. Anti-inflammatory tirucallane triterpenoids from Anopyxis klaineana Pierre (Engl.), (Rhizophoraceae).
Fitoterapia.
2015 Oct; 106(?):84-91. doi:
10.1016/j.fitote.2015.08.007. [PMID: 26291645] - Mariana Neves Vieira, Fernanda das Neves Costa, Gilda Guimarães Leitão, Ian Garrard, Peter Hewitson, Svetlana Ignatova, Peter Winterhalter, Gerold Jerz. Schinus terebinthifolius scale-up countercurrent chromatography (Part I): High performance countercurrent chromatography fractionation of triterpene acids with off-line detection using atmospheric pressure chemical ionization mass spectrometry.
Journal of chromatography. A.
2015 Apr; 1389(?):39-48. doi:
10.1016/j.chroma.2015.02.005. [PMID: 25757818] - Ying Wei, Chao-Mei Ma, Tai-Bai Jiang, Jiang Du, Xing Zhou, Guo-Qing Liu, Masao Hattori. Synthesis of piscidinol A derivatives and their ability to inhibit HIV-1 protease.
Journal of Asian natural products research.
2015; 17(11):1079-90. doi:
10.1080/10286020.2015.1084505. [PMID: 26456550] - Lin Jing, Yang-Mei Zhang, Jian-Guang Luo, Ling-Yi Kong. Tirucallane-type triterpenoids from the fruit of Ficus carica and their cytotoxic activity.
Chemical & pharmaceutical bulletin.
2015; 63(3):237-43. doi:
10.1248/cpb.c14-00779. [PMID: 25757495] - Nguyen Huu Toan Phan, Nguyen Thi Dieu Thuan, Ninh Thi Ngoc, Nguyen Phuong Thao, Sohyun Kim, Young Sang Koh, Nguyen Van Thanh, Nguyen Xuan Cuong, Nguyen Hoai Nam, Phan Van Kiem, Young Ho Kim, Chau Van Minh. Anti-inflammatory tirucallane saponins from Paramignya scandens.
Chemical & pharmaceutical bulletin.
2015; 63(7):558-64. doi:
10.1248/cpb.c15-00180. [PMID: 26133071] - Jiang Hu, Yan Song, Hui Li, Benshou Yang, Xia Mao, YongMao Zhao, Xiaodong Shi. Cytotoxic and anti-inflammatory tirucallane triterpenoids from Dysoxylum binectariferum.
Fitoterapia.
2014 Dec; 99(?):86-91. doi:
10.1016/j.fitote.2014.09.010. [PMID: 25256064] - Kiettipum Phontree, Jirapast Sichaem, Suttira Khumkratok, Pongpun Siripong, Santi Tip-pyang. Trichostemonoate, a new anticancer tirucallane from the stem bark of Walsura trichostemon.
Natural product communications.
2014 Sep; 9(9):1253-4. doi:
". [PMID: 25918785] - Thiago R Morais, Thais A da Costa-Silva, Andre G Tempone, Samanta Etel T Borborema, Marcus T Scotti, Raquel Maria F de Sousa, Ana Carolina C Araujo, Alberto de Oliveira, Sérgio Antônio L de Morais, Patricia Sartorelli, João Henrique G Lago. Antiparasitic activity of natural and semi-synthetic tirucallane triterpenoids from Schinus terebinthifolius (Anacardiaceae): structure/activity relationships.
Molecules (Basel, Switzerland).
2014 May; 19(5):5761-76. doi:
10.3390/molecules19055761. [PMID: 24802987] - Hui Chen, Shuang-Gang Ma, Zhen-Feng Fang, Jian Bai, Shi-Shan Yu, Xiao-Guang Chen, Qi Hou, Shao-Peng Yuan, Xia Chen. Tirucallane triterpenoids from the stems of Brucea mollis.
Chemistry & biodiversity.
2013 Apr; 10(4):695-702. doi:
10.1002/cbdv.201200079. [PMID: 23576355] - Qingjie Zhao, Yan Song, Chuanwei Feng, Haisheng Chen. Cytotoxic tirucallane triterpenoids from the stem bark of Melia toosendan.
Archives of pharmacal research.
2012 Nov; 35(11):1903-7. doi:
10.1007/s12272-012-1106-7. [PMID: 23212631] - Qi Zeng, Bin Guan, Jiang-Jiang Qin, Chun-Hui Wang, Xiang-Rong Cheng, Jie Ren, Shi-Kai Yan, Hui-Zi Jin, Wei-Dong Zhang. 2,3-Seco- and 3,4-seco-tirucallane triterpenoid derivatives from the stems of Aphanamixis grandifolia Blume.
Phytochemistry.
2012 Aug; 80(?):148-55. doi:
10.1016/j.phytochem.2012.05.017. [PMID: 22683319] - Chao Guo, Jun-Song Wang, Yao Zhang, Lei Yang, Peng-Ran Wang, Ling-Yi Kong. Relationship of chemical structure to in vitro anti-inflammatory activity of tirucallane triterpenoids from the stem barks of Aphanamixis grandifolia.
Chemical & pharmaceutical bulletin.
2012; 60(8):1003-10. doi:
10.1248/cpb.c12-00252. [PMID: 22863704] - Jun-Song Wang, Yao Zhang, Dan-Dan Wei, Xiao-Bing Wang, Jun Luo, Ling-Yi Kong. Novel tirucallane-type triterpenoids from Aphanamixis grandifolia.
Chemistry & biodiversity.
2011 Nov; 8(11):2025-34. doi:
10.1002/cbdv.201000250. [PMID: 22083915] - JinXiong Chen, JianChao Chen, Yun Sun, YuXin Yan, LingMei Kong, Yan Li, MingHua Qiu. Cytotoxic triterpenoids from Azadirachta indica.
Planta medica.
2011 Nov; 77(16):1844-7. doi:
10.1055/s-0030-1271197. [PMID: 21674442] - Hong-Li Huang, Chun-Ming Wang, Zhen-Hua Wang, Ming-Jun Yao, Guang-Tian Han, Ji-Cheng Yuan, Kun Gao, Cheng-Shan Yuan. Tirucallane-type triterpenoids from Dysoxylum lenticellatum.
Journal of natural products.
2011 Oct; 74(10):2235-42. doi:
10.1021/np2006296. [PMID: 21954912] - Ki Hyun Kim, Sang Un Choi, Young Choong Kim, Kang Ro Lee. Tirucallane triterpenoids from Cornus walteri.
Journal of natural products.
2011 Jan; 74(1):54-9. doi:
10.1021/np100660v. [PMID: 21182258] - Yao Zhang, Junsong Wang, Dandan Wei, Xiaobing Wang, Jun Luo, Jianguang Luo, Lingyi Kong. Cytotoxic tirucallane C26 triterpenoids from the stem barks of Aphanamixis grandifolia.
Phytochemistry.
2010 Dec; 71(17-18):2199-204. doi:
10.1016/j.phytochem.2010.08.017. [PMID: 20851441] - Xiang-Yun Zhang, Yan Li, Yuan-Yuan Wang, Xiang-Hai Cai, Tao Feng, Xiao-Dong Luo. Tirucallane-type alkaloids from the bark of Dysoxylum laxiracemosum.
Journal of natural products.
2010 Aug; 73(8):1385-8. doi:
10.1021/np100307f. [PMID: 20669932] - Nikoletta G Ntalli, Filippo Cottiglia, Carlos A Bueno, Laura E Alché, Marco Leonti, Simona Vargiu, Ersilia Bifulco, Urania Menkissoglu-Spiroudi, Pierluigi Caboni. Cytotoxic tirucallane triterpenoids from Melia azedarach fruits.
Molecules (Basel, Switzerland).
2010 Aug; 15(9):5866-77. doi:
10.3390/molecules15095866. [PMID: 20802401] - Jing Ning, Hong-Ping He, Shi-Fei Li, Zhao-Liang Geng, Xin Fang, Ying-Tong Di, Shun-Lin Li, Xiao-Jiang Hao. Triterpenoids from the leaves of Toona ciliata.
Journal of Asian natural products research.
2010 Jun; 12(6):448-52. doi:
10.1080/10286020.2010.493329. [PMID: 20552482] - Aydee C Estrada, Tatiana Syrovets, Kai Pitterle, Oleg Lunov, Berthold Büchele, Judith Schimana-Pfeifer, Thomas Schmidt, Samy A F Morad, Thomas Simmet. Tirucallic acids are novel pleckstrin homology domain-dependent Akt inhibitors inducing apoptosis in prostate cancer cells.
Molecular pharmacology.
2010 Mar; 77(3):378-87. doi:
10.1124/mol.109.060475. [PMID: 20018812] - Junichi Shinozaki, Masaaki Shibuya, Yukiko Takahata, Kazuo Masuda, Yutaka Ebizuka. Molecular evolution of fern squalene cyclases.
Chembiochem : a European journal of chemical biology.
2010 Feb; 11(3):426-33. doi:
10.1002/cbic.200900672. [PMID: 20082400] - Wendong Xu, Chenggen Zhu, Wei Cheng, Xiaona Fan, Xiaoguang Chen, Sen Yang, Ying Guo, Fei Ye, Jiangong Shi. Chemical Constituents of the Roots of Euphorbia micractina.
Journal of natural products.
2009 Sep; 72(9):1620-6. doi:
10.1021/np900305j. [PMID: 19702283] - Wei Ni, Yan Hua, Hai-Yang Liu, Rong-Wei Teng, Yun-Cheung Kong, Xiu-Ying Hu, Chang-Xiang Chen. Tirucallane-type triterpenoid saponins from the roots of Sapindus mukorossi.
Chemical & pharmaceutical bulletin.
2006 Oct; 54(10):1443-6. doi:
10.1248/cpb.54.1443. [PMID: 17015987]
