p-Aminohippurate (BioDeep_00000847816)

   


代谢物信息卡片


p-Aminohippurate

化学式: C9H9N2O3- (193.06131440000001)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC(=CC=C1C(=O)NCC(=O)[O-])N
InChI: InChI=1S/C9H10N2O3/c10-7-3-1-6(2-4-7)9(14)11-5-8(12)13/h1-4H,5,10H2,(H,11,14)(H,12,13)/p-1

描述信息

A hippurate that is the conjugate base of p-aminohippuric acid, arising from deprotonation of the carboxy group.
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents

同义名列表

1 个代谢物同义名

p-Aminohippurate



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Kelly E Mercer, Gabriella A M Ten Have, Lindsay Pack, Renny Lan, Nicolaas E P Deutz, Sean H Adams, Brian D Piccolo. Net release and uptake of xenometabolites across intestinal, hepatic, muscle, and renal tissue beds in healthy conscious pigs. American journal of physiology. Gastrointestinal and liver physiology. 2020 08; 319(2):G133-G141. doi: 10.1152/ajpgi.00153.2020. [PMID: 32538141]
  • Atcharaporn Ontawong, Naruwan Saowakon, Pornpun Vivithanaporn, Anchalee Pongchaidecha, Narissara Lailerd, Doungporn Amornlerdpison, Anusorn Lungkaphin, Chutima Srimaroeng. Antioxidant and renoprotective effects of Spirogyra neglecta (Hassall) Kützing extract in experimental type 2 diabetic rats. BioMed research international. 2013; 2013(?):820786. doi: 10.1155/2013/820786. [PMID: 23862157]
  • Tao Liu, Qiang Meng, Changyuan Wang, Qi Liu, Xinjin Guo, Huijun Sun, Jinyong Peng, Xiaochi Ma, Taiichi Kaku, Kexin Liu. Changes in expression of renal Oat1, Oat3 and Mrp2 in cisplatin-induced acute renal failure after treatment of JBP485 in rats. Toxicology and applied pharmacology. 2012 Nov; 264(3):423-30. doi: 10.1016/j.taap.2012.08.019. [PMID: 22992436]
  • Ho Jung Shin, Choong Hee Lee, Su-Jin Park, Jae-Gook Shin, Im-Sook Song. Establishment and characterization of Mardin-Darby canine kidney cells stably expressing human organic anion transporters. Archives of pharmacal research. 2010 May; 33(5):709-16. doi: 10.1007/s12272-010-0510-0. [PMID: 20512469]
  • Sergio Lucio Becerra-Torres, María Luisa Rodríguez-Vázquez, Iliana Ernestina Medina-Ramírez, Fernando Jaramillo-Juárez. The flavonoid quercetin protects and prevents against potassium dichromate-induced systemic peroxidation of lipids and diminution in renal clearance of para-aminohippuric acid and inulin in the rat. Drug and chemical toxicology. 2009; 32(1):88-91. doi: 10.1080/01480540802449951. [PMID: 19514943]
  • Takuya Matsumoto, Yuji Nagashima, Hiroyuki Kusuhara, Yuichi Sugiyama, Shoichiro Ishizaki, Kuniyoshi Shimakura, Kazuo Shiomi. Involvement of carrier-mediated transport system in uptake of tetrodotoxin into liver tissue slices of puffer fish Takifugu rubripes. Toxicon : official journal of the International Society on Toxinology. 2007 Aug; 50(2):173-9. doi: 10.1016/j.toxicon.2007.03.004. [PMID: 17451768]
  • Dennis R Groothuis, Michael W Vavra, Kurt E Schlageter, Eric W-Y Kang, Andrea C Itskovich, Shannon Hertzler, Cathleen V Allen, Howard L Lipton. Efflux of drugs and solutes from brain: the interactive roles of diffusional transcapillary transport, bulk flow and capillary transporters. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2007 Jan; 27(1):43-56. doi: 10.1038/sj.jcbfm.9600315. [PMID: 16639426]
  • Stella T Mahieu, Marisa Gionotti, Néstor Millen, María Mónica Elías. Effect of chronic accumulation of aluminum on renal function, cortical renal oxidative stress and cortical renal organic anion transport in rats. Archives of toxicology. 2003 Nov; 77(11):605-12. doi: 10.1007/s00204-003-0496-1. [PMID: 12928767]
  • Chang Beohm Ahn, Choon Ho Song, Woo Hwan Kim, Yong Keun Kim. Effects of Juglans sinensis Dode extract and antioxidant on mercury chloride-induced acute renal failure in rabbits. Journal of ethnopharmacology. 2002 Sep; 82(1):45-9. doi: 10.1016/s0378-8741(02)00124-1. [PMID: 12169405]
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  • D K Obatomi, N T Thanh, S Brant, P H Bach. The toxic mechanism and metabolic effects of atractyloside in precision-cut pig kidney and liver slices. Archives of toxicology. 1998 Jul; 72(8):524-30. doi: 10.1007/s002040050537. [PMID: 9765068]
  • D K Obatomi, S Brant, V Anthonypillai, P H Bach. Toxicity of atractyloside in precision-cut rat and porcine renal and hepatic tissue slices. Toxicology and applied pharmacology. 1998 Jan; 148(1):35-45. doi: 10.1006/taap.1997.8316. [PMID: 9465261]
  • Y K Kim, J S Jung, S H Lee, Y W Kim. Effects of antioxidants and Ca2+ in cisplatin-induced cell injury in rabbit renal cortical slices. Toxicology and applied pharmacology. 1997 Oct; 146(2):261-9. doi: 10.1006/taap.1997.8252. [PMID: 9344894]
  • P Raymond, G L Plaa. Effect of dosing vehicle on the hepatotoxicity of CCl4 and nephrotoxicity of CHCl3 in rats. Journal of toxicology and environmental health. 1997 Aug; 51(5):463-76. doi: 10.1080/00984109708984037. [PMID: 9233380]
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  • J G Zhang, W E Lindup. Tiopronin protects against the nephrotoxicity of cisplatin in rat renal cortical slices in vitro. Toxicology and applied pharmacology. 1996 Dec; 141(2):425-33. doi: 10.1006/taap.1996.0308. [PMID: 8975767]
  • Y K Kim, Y H Kim. Differential effect of Ca2+ on oxidant-induced lethal cell injury and alterations of membrane functional integrity in renal cortical slices. Toxicology and applied pharmacology. 1996 Dec; 141(2):607-16. doi: 10.1006/taap.1996.0327. [PMID: 8975786]
  • T Pelikánová, I Smrcková, J Krízová, J Stríbrná, V Lánská. Effects of insulin and lipid emulsion on renal haemodynamics and renal sodium handling in IDDM patients. Diabetologia. 1996 Sep; 39(9):1074-82. doi: 10.1007/bf00400657. [PMID: 8877292]
  • G Inselmann, A Blöhmer, W Kottny, U Nellessen, H Hänel, H T Heidemann. Modification of cisplatin-induced renal p-aminohippurate uptake alteration and lipid peroxidation by thiols, Ginkgo biloba extract, deferoxamine and torbafylline. Nephron. 1995; 70(4):425-9. doi: 10.1159/000188640. [PMID: 7477647]
  • H Bräunlich, F Marx, G Stein. Glutathione status, lipid peroxidation and kidney function in streptozotocin diabetic rats. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie. 1994 Jul; 46(2):143-7. doi: 10.1016/s0940-2993(11)80045-x. [PMID: 7987072]
  • S S Choi, K D Huh, J S Woo, Y K Kim. Effect of t-butylhydroperoxide on p-aminohippurat uptake in rabbit renal cortical slices. The Korean journal of internal medicine. 1994 Jul; 9(2):105-12. doi: 10.3904/kjim.1994.9.2.105. [PMID: 7865484]
  • J G Zhang, L F Zhong, M Zhang, X L Ma, Y X Xia, W E Lindup. Amelioration of cisplatin toxicity in rat renal cortical slices by dithiothreitol in vitro. Human & experimental toxicology. 1994 Feb; 13(2):89-93. doi: 10.1177/096032719401300205. [PMID: 7908816]
  • K J Ullrich, G Rumrich. Renal transport mechanisms for xenobiotics: chemicals and drugs. The Clinical investigator. 1993 Oct; 71(10):843-8. doi: 10.1007/bf00190334. [PMID: 8305846]
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  • G F Rush, R A Heim, G D Ponsler, J Engelhardt. Cephaloridine-induced renal pathological and biochemical changes in female rabbits and isolated proximal tubules in suspension. Toxicologic pathology. 1992; 20(2):155-68. doi: 10.1177/019262339202000203. [PMID: 1475577]
  • G Inselmann, A Kutzschbach, H T Heidemann. Amphotericin B and sodium deoxycholate induced impairment of renal p-aminohippurate accumulation (PAH) and effect on lipid peroxidation in the rat kidney. Renal failure. 1992; 14(1):17-21. doi: 10.3109/08860229209039112. [PMID: 1561385]
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  • G Inselmann, K Baumann. Effect of cyclosporine A on accumulation of tetraethylammonium and p-aminohippurate, and on lipid peroxidation in rat renal microsomes and cortical slices. Renal failure. 1990; 12(3):165-9. doi: 10.3109/08860229009065559. [PMID: 2287768]
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