2,3-Dipalmitoyl-S-glycerylcysteine (BioDeep_00000847735)
代谢物信息卡片
化学式: C38H73NO6S (671.5158317999999)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCCCCCCCCCCCCCC(=O)OCC(CSCC(C(=O)O)N)OC(=O)CCCCCCCCCCCCCCC
InChI: InChI=1S/C38H73NO6S/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-36(40)44-31-34(32-46-33-35(39)38(42)43)45-37(41)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h34-35H,3-33,39H2,1-2H3,(H,42,43)/t34?,35-/m0/s1
描述信息
An L-cysteine thioether that is L-cysteine in which the hydrogen of the thiol group is substituted by a 2,3-bis(palmitoyloxy)propyl group.
同义名列表
1 个代谢物同义名
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
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INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
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0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Federico Boiardi, Justin Stebbing. Reducing transmission of SARS-CoV-2 with intranasal prophylaxis.
EBioMedicine.
2021 Jan; 63(?):103170. doi:
10.1016/j.ebiom.2020.103170. [PMID: 33340994] - Takashi Akazawa, Toshimitsu Ohashi, Viskam Wijewardana, Kikuya Sugiura, Norimitsu Inoue. Development of a vaccine based on bacteria-mimicking tumor cells coated with novel engineered toll-like receptor 2 ligands.
Cancer science.
2018 May; 109(5):1319-1329. doi:
10.1111/cas.13576. [PMID: 29575556] - Emily J Anstadt, Mai Fujiwara, Nicholas Wasko, Frank Nichols, Robert B Clark. TLR Tolerance as a Treatment for Central Nervous System Autoimmunity.
Journal of immunology (Baltimore, Md. : 1950).
2016 09; 197(6):2110-8. doi:
10.4049/jimmunol.1600876. [PMID: 27503211] - Weiguang Zeng, Amabel C L Tan, Kylie Horrocks, David C Jackson. A lipidated form of the extracellular domain of influenza M2 protein as a self-adjuvanting vaccine candidate.
Vaccine.
2015 Jul; 33(30):3526-32. doi:
10.1016/j.vaccine.2015.05.053. [PMID: 26049002] - Joanna C A Cobbin, Weiguang Zeng, David C Jackson, Lorena E Brown. Different arms of the adaptive immune system induced by a combination vaccine work in concert to provide enhanced clearance of influenza.
PloS one.
2014; 9(12):e115356. doi:
10.1371/journal.pone.0115356. [PMID: 25522323] - Ryoko Sawahata, Hiroaki Shime, Sayuri Yamazaki, Norimitsu Inoue, Takashi Akazawa, Yukari Fujimoto, Koichi Fukase, Misako Matsumoto, Tsukasa Seya. Failure of mycoplasma lipoprotein MALP-2 to induce NK cell activation through dendritic cell TLR2.
Microbes and infection.
2011 Apr; 13(4):350-8. doi:
10.1016/j.micinf.2010.12.003. [PMID: 21172450] - Weiguang Zeng, Emily M Eriksson, Andrew Lew, David C Jackson. Lipidation of intact proteins produces highly immunogenic vaccine candidates.
Molecular immunology.
2011 Jan; 48(4):490-6. doi:
10.1016/j.molimm.2010.10.003. [PMID: 21056473] - Masahiro Azuma, Ryoko Sawahata, Yuusuke Akao, Takashi Ebihara, Sayuri Yamazaki, Misako Matsumoto, Masahito Hashimoto, Koichi Fukase, Yukari Fujimoto, Tsukasa Seya. The peptide sequence of diacyl lipopeptides determines dendritic cell TLR2-mediated NK activation.
PloS one.
2010 Sep; 5(9):. doi:
10.1371/journal.pone.0012550. [PMID: 20824059] - Weiguang Zeng, Emily Eriksson, Brendon Chua, Lara Grollo, David C Jackson. Structural requirement for the agonist activity of the TLR2 ligand Pam2Cys.
Amino acids.
2010 Jul; 39(2):471-80. doi:
10.1007/s00726-009-0463-0. [PMID: 20091415] - David Pejoski, Weiguang Zeng, Steven Rockman, Lorena E Brown, David C Jackson. A lipopeptide based on the M2 and HA proteins of influenza A viruses induces protective antibody.
Immunology and cell biology.
2010 Jul; 88(5):605-11. doi:
10.1038/icb.2010.15. [PMID: 20177411] - Georgia Deliyannis, Katherine Kedzierska, Yuk Fai Lau, Weiguang Zeng, Stephen J Turner, David C Jackson, Lorena E Brown. Intranasal lipopeptide primes lung-resident memory CD8+ T cells for long-term pulmonary protection against influenza.
European journal of immunology.
2006 Mar; 36(3):770-8. doi:
10.1002/eji.200535217. [PMID: 16435281]