(2R)-3-(4-Cyanophenoxy)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide (BioDeep_00000847177)
代谢物信息卡片
(2R)-3-(4-Cyanophenoxy)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide
化学式: C19H14F3N3O3 (389.0987)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(COC1=CC=C(C=C1)C#N)(C(=O)NC2=CC(=C(C=C2)C#N)C(F)(F)F)O
InChI: InChI=1S/C19H14F3N3O3/c1-18(27,11-28-15-6-2-12(9-23)3-7-15)17(26)25-14-5-4-13(10-24)16(8-14)19(20,21)22/h2-8,27H,11H2,1H3,(H,25,26)/t18-/m1/s1
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代谢反应
0 个相关的代谢反应过程信息。
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0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
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文献列表
- Tim Sobolevsky, Brian Ahrens. High-throughput liquid chromatography tandem mass spectrometry assay as initial testing procedure for analysis of total urinary fraction.
Drug testing and analysis.
2021 Feb; 13(2):283-298. doi:
10.1002/dta.2917. [PMID: 32852861] - Katja Walpurgis, Ana Rubio, Felicitas Wagener, Oliver Krug, Andre Knoop, Christian Görgens, Sven Guddat, Mario Thevis. Elimination profiles of microdosed ostarine mimicking contaminated products ingestion.
Drug testing and analysis.
2020 Nov; 12(11-12):1570-1580. doi:
10.1002/dta.2933. [PMID: 32959982] - Marina Komrakova, Judith Furtwängler, Daniel Bernd Hoffmann, Wolfgang Lehmann, Arndt Friedrich Schilling, Stephan Sehmisch. The Selective Androgen Receptor Modulator Ostarine Improves Bone Healing in Ovariectomized Rats.
Calcified tissue international.
2020 02; 106(2):147-157. doi:
10.1007/s00223-019-00613-1. [PMID: 31531719] - Azamat Temerdashev, Ekaterina Dmitrieva, Alice Azaryan, Elina Gashimova. A novel approach to the quantification of urinary aryl-propionamide-derived SARMs by UHPLC-MS/MS.
Biomedical chromatography : BMC.
2020 Jan; 34(1):e4700. doi:
10.1002/bmc.4700. [PMID: 31734960] - Neeraj Garg, Annelie Hansson, Heather K Knych, Scott D Stanley, Mario Thevis, Ulf Bondesson, Mikael Hedeland, Daniel Globisch. Structural elucidation of major selective androgen receptor modulator (SARM) metabolites for doping control.
Organic & biomolecular chemistry.
2018 01; 16(5):698-702. doi:
10.1039/c7ob03030d. [PMID: 29319101] - Nora Cesbron, Alexandre Sydor, Mylène Penot, Stéphanie Prevost, Bruno Le Bizec, Gaud Dervilly-Pinel. Analytical strategies to detect enobosarm administration in bovines.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment.
2017 Apr; 34(4):632-640. doi:
10.1080/19440049.2016.1258122. [PMID: 27827563] - Suriyan Ponnusamy, Ryan D Sullivan, Thirumagal Thiyagarajan, Heather Tillmann, Robert H Getzenberg, Ramesh Narayanan. Tissue Selective Androgen Receptor Modulators (SARMs) Increase Pelvic Floor Muscle Mass in Ovariectomized Mice.
Journal of cellular biochemistry.
2017 03; 118(3):640-646. doi:
10.1002/jcb.25751. [PMID: 27681158] - Laure Beucher, Gaud Dervilly-Pinel, Nora Cesbron, Mylène Penot, Audrey Gicquiau, Fabrice Monteau, Bruno Le Bizec. Specific characterization of non-steroidal selective androgen peceptor modulators using supercritical fluid chromatography coupled to ion-mobility mass spectrometry: application to the detection of enobosarm in bovine urine.
Drug testing and analysis.
2017 Feb; 9(2):179-187. doi:
10.1002/dta.1951. [PMID: 26990774] - Christopher C Coss, Amanda Jones, James T Dalton. Pharmacokinetic drug interactions of the selective androgen receptor modulator GTx-024(Enobosarm) with itraconazole, rifampin, probenecid, celecoxib and rosuvastatin.
Investigational new drugs.
2016 08; 34(4):458-67. doi:
10.1007/s10637-016-0353-8. [PMID: 27105861] - Annelie Hansson, Heather Knych, Scott Stanley, Mario Thevis, Ulf Bondesson, Mikael Hedeland. Investigation of the selective androgen receptor modulators S1, S4 and S22 and their metabolites in equine plasma using high-resolution mass spectrometry.
Rapid communications in mass spectrometry : RCM.
2016 Apr; 30(7):833-42. doi:
10.1002/rcm.7512. [PMID: 26969924] - Juhyun Kim, Ronghua Wang, Karen A Veverka, James T Dalton. Absorption, distribution, metabolism and excretion of the novel SARM GTx-024 [(S)-N-(4-cyano-3-(trifluoromethyl)phenyl)-3-(4-cyanophenoxy)-2-hydroxy-2-methylpropanamide] in rats.
Xenobiotica; the fate of foreign compounds in biological systems.
2013 Nov; 43(11):993-1009. doi:
10.3109/00498254.2013.788233. [PMID: 24074268] - Eva de Rijke, Martien L Essers, Jeroen C W Rijk, Mario Thevis, Toine F H Bovee, Leendert A van Ginkel, Saskia S Sterk. Selective androgen receptor modulators: in vitro and in vivo metabolism and analysis.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment.
2013; 30(9):1517-26. doi:
10.1080/19440049.2013.810346. [PMID: 23883284] - Mario Thevis, Andreas Thomas, Ines Möller, Hans Geyer, James T Dalton, Wilhelm Schänzer. Mass spectrometric characterization of urinary metabolites of the selective androgen receptor modulator S-22 to identify potential targets for routine doping controls.
Rapid communications in mass spectrometry : RCM.
2011 Aug; 25(15):2187-95. doi:
10.1002/rcm.5100. [PMID: 21710598]
