(R)-Dobutamine (BioDeep_00000847028)

   


代谢物信息卡片


(R)-Dobutamine

化学式: C18H23NO3 (301.1677848)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(CCC1=CC=C(C=C1)O)NCCC2=CC(=C(C=C2)O)O
InChI: InChI=1S/C18H23NO3/c1-13(2-3-14-4-7-16(20)8-5-14)19-11-10-15-6-9-17(21)18(22)12-15/h4-9,12-13,19-22H,2-3,10-11H2,1H3/t13-/m1/s1

描述信息

同义名列表

1 个代谢物同义名

(R)-Dobutamine



数据库引用编号

3 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Ljubica Spasojević Kosić, Dragiša R Trailović, Radomir Matunović. Resting and dobutamine stress test induced serum concentrations of brain natriuretic peptide in German Shepherd dogs. Research in veterinary science. 2012 Dec; 93(3):1446-53. doi: 10.1016/j.rvsc.2012.04.002. [PMID: 22537461]
  • Paola Papoff, Elena Caresta, Paolo Versacci, Raffaella Pinto, Corrado Moretti, Fabio Midulla. Beneficial effects of levosimendan in infants with sepsis-associated cardiac dysfunction: report of 2 cases. Pediatric emergency care. 2012 Oct; 28(10):1062-5. doi: 10.1097/pec.0b013e31826cebe6. [PMID: 23034494]
  • Louise Marks, Samantha Borland, Karen Philp, Lorna Ewart, Pierre Lainée, Matthew Skinner, Sarah Kirk, Jean-Pierre Valentin. The role of the anaesthetised guinea-pig in the preclinical cardiac safety evaluation of drug candidate compounds. Toxicology and applied pharmacology. 2012 Sep; 263(2):171-83. doi: 10.1016/j.taap.2012.06.007. [PMID: 22714037]
  • X Valette, S Lemoine, S Allouche, J-L Gérard, J-L Hanouz. Effect of lipopolysaccharide, cytokines, and catecholamines on brain natriuretic peptide release from human myocardium. Acta anaesthesiologica Scandinavica. 2012 Aug; 56(7):860-5. doi: 10.1111/j.1399-6576.2012.02683.x. [PMID: 22471594]
  • Ramona Steri, Janosch Achenbach, Dieter Steinhilber, Manfred Schubert-Zsilavecz, Ewgenij Proschak. Investigation of imatinib and other approved drugs as starting points for antidiabetic drug discovery with FXR modulating activity. Biochemical pharmacology. 2012 Jun; 83(12):1674-81. doi: 10.1016/j.bcp.2012.02.027. [PMID: 22414727]
  • Priyatansh Gurha, Cei Abreu-Goodger, Tiannan Wang, Maricela O Ramirez, Ana L Drumond, Stijn van Dongen, Yuqing Chen, Nenad Bartonicek, Anton J Enright, Brendan Lee, Robert J Kelm, Anilkumar K Reddy, George E Taffet, Allan Bradley, Xander H Wehrens, Mark L Entman, Antony Rodriguez. Targeted deletion of microRNA-22 promotes stress-induced cardiac dilation and contractile dysfunction. Circulation. 2012 Jun; 125(22):2751-61. doi: 10.1161/circulationaha.111.044354. [PMID: 22570371]
  • Dilek Memiş, Mehmet Turan Inal, Necdet Sut. The effects of levosimendan vs dobutamine added to dopamine on liver functions assessed with noninvasive liver function monitoring in patients with septic shock. Journal of critical care. 2012 Jun; 27(3):318.e1-6. doi: 10.1016/j.jcrc.2011.06.008. [PMID: 21855289]
  • Koudai Ikemoto, Tadahiko Ishiyama, Kazuhiro Shibuya, Noriaki Iwao, Katsumi Okuyama, Takashi Matsukawa. [Use of cryoprecipitate for dilution coagulopathy in a 7-month-old infant]. Masui. The Japanese journal of anesthesiology. 2012 Apr; 61(4):404-6. doi: NULL. [PMID: 22590946]
  • Madhusudanarao Vuda, Lukas Brander, Ralph Schröder, Stephan M Jakob, Jukka Takala, Siamak Djafarzadeh. Effects of catecholamines on hepatic and skeletal muscle mitochondrial respiration after prolonged exposure to faecal peritonitis in pigs. Innate immunity. 2012 Apr; 18(2):217-30. doi: 10.1177/1753425911398279. [PMID: 21525237]
  • Khaled M Mahmoud, Amany S Ammar. Norepinephrine supplemented with dobutamine or epinephrine for the cardiovascular support of patients with septic shock. Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine. 2012 Apr; 16(2):75-80. doi: 10.4103/0972-5229.99110. [PMID: 22988361]
  • Ismaila A Raji, Pierre Mugabo, Kenechukwu Obikeze. Effect of Tulbaghia violacea on the blood pressure and heart rate in male spontaneously hypertensive Wistar rats. Journal of ethnopharmacology. 2012 Mar; 140(1):98-106. doi: 10.1016/j.jep.2011.12.034. [PMID: 22222281]
  • Ruth Heying, Edith Wehage, Katharina Schumacher, Peter Tassani, Felix Haas, Rudiger Lange, John Hess, Marie-Christine Seghaye. Dexamethasone pretreatment provides antiinflammatory and myocardial protection in neonatal arterial switch operation. The Annals of thoracic surgery. 2012 Mar; 93(3):869-76. doi: 10.1016/j.athoracsur.2011.11.059. [PMID: 22289904]
  • N Chin Lai, Tong Tang, Mei Hua Gao, Miho Saito, Atsushi Miyanohara, H Kirk Hammond. Improved function of the failing rat heart by regulated expression of insulin-like growth factor I via intramuscular gene transfer. Human gene therapy. 2012 Mar; 23(3):255-61. doi: 10.1089/hum.2011.094. [PMID: 22017392]
  • Yonggang Ma, Ying Ann Chiao, Jianhua Zhang, Anne M Manicone, Yu-Fang Jin, Merry L Lindsey. Matrix metalloproteinase-28 deletion amplifies inflammatory and extracellular matrix responses to cardiac aging. Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada. 2012 Feb; 18(1):81-90. doi: 10.1017/s1431927611012220. [PMID: 22153350]
  • Koen J Hartemink, A B Johan Groeneveld. Vasopressors and inotropes in the treatment of human septic shock: effect on innate immunity?. Inflammation. 2012 Feb; 35(1):206-13. doi: 10.1007/s10753-011-9306-8. [PMID: 21347606]
  • Ajay H Raithatha, Daniele C Bryden. Use of intravenous immunoglobulin therapy in the treatment of septic shock, in particular severe invasive group A streptococcal disease. Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine. 2012 Jan; 16(1):37-40. doi: 10.4103/0972-5229.94433. [PMID: 22557832]
  • Didier Payen, Anne-Claire Lukaszewicz, Matthieu Legrand, Etienne Gayat, Valérie Faivre, Bruno Megarbane, Elie Azoulay, Fabienne Fieux, Dominique Charron, Pascale Loiseau, Marc Busson. A multicentre study of acute kidney injury in severe sepsis and septic shock: association with inflammatory phenotype and HLA genotype. PloS one. 2012; 7(6):e35838. doi: 10.1371/journal.pone.0035838. [PMID: 22701553]
  • Joon Lee, Rishi Kothari, Joseph A Ladapo, Daniel J Scott, Leo A Celi. Interrogating a clinical database to study treatment of hypotension in the critically ill. BMJ open. 2012; 2(3):. doi: 10.1136/bmjopen-2012-000916. [PMID: 22685222]
  • Vin-Cent Wu, Tao-Min Huang, Pei-Chen Wu, Wei-Jie Wang, Chia-Ter Chao, Shao-Yu Yang, Chih-Chung Shiao, Fu-Chang Hu, Chun-Fu Lai, Yu-Feng Lin, Yin-Yi Han, Yih-Sharng Chen, Ron-Bin Hsu, Guang-Huar Young, Shoei-Shen Wang, Pi-Ru Tsai, Yung-Ming Chen, Ting-Ting Chao, Wen-Je Ko, Kwan-Dun Wu. Preoperative proteinuria is associated with long-term progression to chronic dialysis and mortality after coronary artery bypass grafting surgery. PloS one. 2012; 7(1):e27687. doi: 10.1371/journal.pone.0027687. [PMID: 22276092]
  • Tunggul Adi Purwonugroho, Suvatna Chulavatnatol, Yupaporn Preechagoon, Busba Chindavijak, Kumthorn Malathum, Pakwan Bunuparadah. Population pharmacokinetics of vancomycin in Thai patients. TheScientificWorldJournal. 2012; 2012(?):762649. doi: 10.1100/2012/762649. [PMID: 22547995]
  • Ken Ishikawa, Li Wan, Paolo Calzavacca, Rinaldo Bellomo, Michael Bailey, Clive N May. The effects of terlipressin on regional hemodynamics and kidney function in experimental hyperdynamic sepsis. PloS one. 2012; 7(2):e29693. doi: 10.1371/journal.pone.0029693. [PMID: 22355305]
  • W Todd Cade, Dominic N Reeds, E Turner Overton, Pilar Herrero, Alan D Waggoner, Victor G Davila-Roman, Sherry Lassa-Claxton, Robert J Gropler, Pablo F Soto, Melissa J Krauss, Kevin E Yarasheski, Linda R Peterson. Effects of human immunodeficiency virus and metabolic complications on myocardial nutrient metabolism, blood flow, and oxygen consumption: a cross-sectional analysis. Cardiovascular diabetology. 2011 Dec; 10(?):111. doi: 10.1186/1475-2840-10-111. [PMID: 22151886]
  • Louis W Wang, Magid A Fahim, Andrew Hayen, Ruth L Mitchell, Laura Baines, Stephen Lord, Jonathan C Craig, Angela C Webster. Cardiac testing for coronary artery disease in potential kidney transplant recipients. The Cochrane database of systematic reviews. 2011 Dec; ?(12):CD008691. doi: 10.1002/14651858.cd008691.pub2. [PMID: 22161434]
  • Helene von Bibra, Martin St John Sutton. Impact of diabetes on postinfarction heart failure and left ventricular remodeling. Current heart failure reports. 2011 Dec; 8(4):242-51. doi: 10.1007/s11897-011-0070-8. [PMID: 21842146]
  • André Loureiro Rosário, Marcelo Park, Milena Karina Brunialti, Marialice Mendes, Marjorie Rapozo, Denise Fernandes, Reinaldo Salomão, Francisco Rafael Laurindo, Guilherme Paula Schettino, Luciano Cesar P Azevedo. SvO(2)-guided resuscitation for experimental septic shock: effects of fluid infusion and dobutamine on hemodynamics, inflammatory response, and cardiovascular oxidative stress. Shock (Augusta, Ga.). 2011 Dec; 36(6):604-12. doi: 10.1097/shk.0b013e3182336aa4. [PMID: 21921835]
  • Robert J Brosnan, Eugene P Steffey, André Escobar, Mine Palazoglu, Oliver Fiehn. Anesthetic induction with guaifenesin and propofol in adult horses. American journal of veterinary research. 2011 Dec; 72(12):1569-75. doi: 10.2460/ajvr.72.12.1569. [PMID: 22126682]
  • Frederick W Endorf, David J Dries. Burn resuscitation. Scandinavian journal of trauma, resuscitation and emergency medicine. 2011 Nov; 19(?):69. doi: 10.1186/1757-7241-19-69. [PMID: 22078326]
  • Mark A Lovich, Abraham E Wei, Mikhail Y Maslov, Peter I Wu, Elazer R Edelman. Local epicardial inotropic drug delivery allows targeted pharmacologic intervention with preservation of myocardial loading conditions. Journal of pharmaceutical sciences. 2011 Nov; 100(11):4993-5006. doi: 10.1002/jps.22681. [PMID: 21721001]
  • Raul A Nachar, Erin A Booth, Philippe Friedlich, Matthew Borzage, Sadaf Soleymani, Michael D Wider, Istvan Seri. Dose-dependent hemodynamic and metabolic effects of vasoactive medications in normotensive, anesthetized neonatal piglets. Pediatric research. 2011 Nov; 70(5):473-9. doi: 10.1203/pdr.0b013e31822e178e. [PMID: 21775923]
  • Juan J Jiménez, José L Iribarren, Maitane Brouard, Domingo Hernández, Salomé Palmero, Alejandro Jiménez, Leonardo Lorente, Patricia Machado, Juan M Borreguero, José M Raya, Beatriz Martín, Rosalía Pérez, Rafael Martínez, María L Mora. Safety and effectiveness of two treatment regimes with tranexamic acid to minimize inflammatory response in elective cardiopulmonary bypass patients: a randomized double-blind, dose-dependent, phase IV clinical trial. Journal of cardiothoracic surgery. 2011 Oct; 6(?):138. doi: 10.1186/1749-8090-6-138. [PMID: 21999189]
  • Yu Mi Ha, Sun Ah Ham, Young Min Kim, Young Soo Lee, Hye Jung Kim, Han Geuk Seo, Jae Heun Lee, Min Kyu Park, Ki Churl Chang. β₁-adrenergic receptor-mediated HO-1 induction, via PI3K and p38 MAPK, by isoproterenol in RAW 264.7 cells leads to inhibition of HMGB1 release in LPS-activated RAW 264.7 cells and increases in survival rate of CLP-induced septic mice. Biochemical pharmacology. 2011 Oct; 82(7):769-77. doi: 10.1016/j.bcp.2011.06.041. [PMID: 21763292]
  • Dragos Vinereanu, Christopher F Mädler, Carmen Gherghinescu, Andrea Olivia Ciobanu, Alan G Fraser. Cumulative impact of cardiovascular risk factors on regional left ventricular function and reserve: progressive long-axis dysfunction with compensatory radial changes. Echocardiography (Mount Kisco, N.Y.). 2011 Sep; 28(8):813-20. doi: 10.1111/j.1540-8175.2011.01456.x. [PMID: 21827541]
  • Christopher T Stephens, Nabeel Uwaydah, George C Kramer, Donald S Prough, Michael Salter, Michael P Kinsky. Vascular and extravascular volume expansion of dobutamine and norepinephrine in normovolemic sheep. Shock (Augusta, Ga.). 2011 Sep; 36(3):303-11. doi: 10.1097/shk.0b013e318225b031. [PMID: 21654559]
  • Ida Casella, Caterina Ambrosio, Maria Cristina Grò, Paola Molinari, Tommaso Costa. Divergent agonist selectivity in activating β1- and β2-adrenoceptors for G-protein and arrestin coupling. The Biochemical journal. 2011 Aug; 438(1):191-202. doi: 10.1042/bj20110374. [PMID: 21561432]
  • Geraldine Diaz, Michael O'Connor. Cardiovascular and renal complications in patients receiving a solid-organ transplant. Current opinion in critical care. 2011 Aug; 17(4):382-9. doi: 10.1097/mcc.0b013e328348bf1f. [PMID: 21677579]
  • Marek Waliszek, Agnieszka Waliszek-Iwanicka, Tomasz Grycewicz, Piotr Jurowski, Maciej Banach, Jacek Rysz, Aleksander Goch. Prognostic value of plasma N-terminal pro-B-type natriuretic peptide concentration in patients with normal and impaired left ventricular systolic function undergoing surgery for abdominal aortic aneurysm. Archives of medical science : AMS. 2011 Aug; 7(4):642-7. doi: 10.5114/aoms.2011.24134. [PMID: 22291800]
  • Sameer Ansar, Juraj Koska, Peter D Reaven. Postprandial hyperlipidemia, endothelial dysfunction and cardiovascular risk: focus on incretins. Cardiovascular diabetology. 2011 Jul; 10(?):61. doi: 10.1186/1475-2840-10-61. [PMID: 21736746]
  • Elizabeth C Lorenz, Mark D Stegall, Fernando G Cosio, James M Gloor, Timothy S Larson, Sandra J Taler. The effect of coronary angiography on renal function in preemptive renal transplant candidates. Clinical transplantation. 2011 Jul; 25(4):594-9. doi: 10.1111/j.1399-0012.2010.01347.x. [PMID: 21050272]
  • Vivek B Kute, Pankaj R Shah, Kamal R Goplani, Manoj R Gumber, A V Vanikar, Hargovind L Trivedi. Successful treatment of refractory hypotension, noncardiogenic pulmonary edema and acute kidney injury after an overdose of amlodipine. Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine. 2011 Jul; 15(3):182-4. doi: 10.4103/0972-5229.84901. [PMID: 22013313]
  • Zaccaria Ricci, Rosa Luciano, Isabella Favia, Cristiana Garisto, Maurizio Muraca, Stefano Morelli, Luca Di Chiara, Paola Cogo, Sergio Picardo. High-dose fenoldopam reduces postoperative neutrophil gelatinase-associated lipocaline and cystatin C levels in pediatric cardiac surgery. Critical care (London, England). 2011 Jun; 15(3):R160. doi: 10.1186/cc10295. [PMID: 21714857]
  • Nelva Mata, Rodrigo Alonso, Lina Badimón, Teresa Padró, Francisco Fuentes, Ovidio Muñiz, Francisco Perez-Jiménez, José López-Miranda, Jose L Díaz, Jose I Vidal, A Barba, Mar Piedecausa, Juan F Sanchez, Luis Irigoyen, Eliseo Guallar, José M Ordovas, Pedro Mata. Clinical characteristics and evaluation of LDL-cholesterol treatment of the Spanish Familial Hypercholesterolemia Longitudinal Cohort Study (SAFEHEART). Lipids in health and disease. 2011 Jun; 10(?):94. doi: 10.1186/1476-511x-10-94. [PMID: 21663647]
  • Kimberly M Jeckel, Kelsey E Miller, Adam J Chicco, Phillip L Chapman, Christopher M Mulligan, Paul H Falcone, Melissa L Miller, Michael J Pagliassotti, Melinda A Frye. The role of dietary fatty acids in predicting myocardial structure in fat-fed rats. Lipids in health and disease. 2011 Jun; 10(?):92. doi: 10.1186/1476-511x-10-92. [PMID: 21649916]
  • Jae-Hyeong Park, Kyu Seop Kim, Ji-Young Sul, Sung Kyun Shin, Jun Hyung Kim, Jae-Hwan Lee, Si Wan Choi, Jin-Ok Jeong, In-Whan Seong. Prevalence and patterns of left ventricular dysfunction in patients with pheochromocytoma. Journal of cardiovascular ultrasound. 2011 Jun; 19(2):76-82. doi: 10.4250/jcu.2011.19.2.76. [PMID: 21860721]
  • Shufei Fu, Junhua Zhang, Francesca Menniti-Ippolito, Xiumei Gao, Francesca Galeotti, Marco Massari, Limin Hu, Boli Zhang, Rita Ferrelli, Alice Fauci, Fabio Firenzuoli, Hongcai Shang, Ranieri Guerra, Roberto Raschetti. Huangqi injection (a traditional Chinese patent medicine) for chronic heart failure: a systematic review. PloS one. 2011 May; 6(5):e19604. doi: 10.1371/journal.pone.0019604. [PMID: 21573109]
  • Fernando Ganem, Carlos V Serrano, Juliano L Fernandes, Maria Heloísa S L Blotta, Juliana A Souza, José C Nicolau, José A F Ramires, Whady A Hueb. Preoperative B-type natriuretic peptide, and not the inflammation status, predicts an adverse outcome for patients undergoing heart surgery. Interactive cardiovascular and thoracic surgery. 2011 May; 12(5):778-83. doi: 10.1510/icvts.2010.255257. [PMID: 21297144]
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  • Sheng Feng, Pei Hu, Ji Jiang. Determination of higenamine in human plasma and urine using liquid chromatography coupled to positive electrospray ionization tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2011 Apr; 879(11-12):763-8. doi: 10.1016/j.jchromb.2011.02.019. [PMID: 21393074]
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  • Julie Badin, Thierry Boulain, Stephan Ehrmann, Marie Skarzynski, Anne Bretagnol, Jennifer Buret, Dalila Benzekri-Lefevre, Emmanuelle Mercier, Isabelle Runge, Denis Garot, Armelle Mathonnet, Pierre-François Dequin, Dominique Perrotin. Relation between mean arterial pressure and renal function in the early phase of shock: a prospective, explorative cohort study. Critical care (London, England). 2011; 15(3):R135. doi: 10.1186/cc10253. [PMID: 21645384]
  • François Kerbaul, Youlet By, Vlad Gariboldi, Choukri Mekkaoui, Pierre Fesler, Frédéric Collart, Serge Brimioulle, Yves Jammes, Jean Ruf, Régis Guieu. Acute pulmonary embolism decreases adenosine plasma levels in anesthetized pigs. ISRN cardiology. 2011; 2011(?):750301. doi: 10.5402/2011/750301. [PMID: 22347654]
  • Florian Bossard, Emilie Silantieff, Emmanuelle Lavazais-Blancou, Amal Robay, Christine Sagan, Bertrand Rozec, Chantal Gauthier. β1, β2, and β3 adrenoceptors and Na+/H+ exchanger regulatory factor 1 expression in human bronchi and their modifications in cystic fibrosis. American journal of respiratory cell and molecular biology. 2011 Jan; 44(1):91-8. doi: 10.1165/rcmb.2009-0372oc. [PMID: 20203292]
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