Carbon-11 (BioDeep_00000846665)
代谢物信息卡片
Carbon-11
化学式: CH4 (16.0312984)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C
InChI: InChI=1S/CH4/h1H4/i1-1
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Tianyu Huang, Jiwei Gu, Hao Jiang, Qianwa Liang, Joel S Perlmutter, Zhude Tu. Radiosynthesis and characterization of a carbon-11 PET tracer for receptor-interacting protein kinase 1.
Nuclear medicine and biology.
2022 Jul; 110-111(?):18-27. doi:
10.1016/j.nucmedbio.2022.04.006. [PMID: 35472678] - Avery Powell, Stacy L Wilder, Alexandra B Housh, Stephanie Scott, Mary Benoit, Garren Powell, Spenser Waller, James M Guthrie, Michael J Schueller, Richard A Ferrieri. Examining effects of rhizobacteria in relieving abiotic crop stresses using carbon-11 radiotracing.
Physiologia plantarum.
2022 Mar; 174(2):e13675. doi:
10.1111/ppl.13675. [PMID: 35316539] - Masaya Jimbo, Jack R Andrews, Mohamed E Ahmed, Ayca Dundar, R Jeffrey Karnes, Alan H Bryce, Ayse T Kendi, Eugene D Kwon, Val J Lowe, Michael S Bold. Prognostic role of 11C-choline PET/CT scan in patients with metastatic castrate resistant prostate cancer undergoing primary docetaxel chemotherapy.
The Prostate.
2022 01; 82(1):41-48. doi:
10.1002/pros.24246. [PMID: 34633087] - Miao Chen, Wenjia Zhu, Jianhua Du, Chen Yang, Bing Han, Daobin Zhou, Li Huo, Junling Zhuang. 11C-acetate positron emission tomography is more precise than 18F-fluorodeoxyglucose positron emission tomography in evaluating tumor burden and predicting disease risk of multiple myeloma.
Scientific reports.
2021 11; 11(1):22188. doi:
10.1038/s41598-021-01740-2. [PMID: 34773054] - Shuhei Takatani, Tsuyoshi Tahara, Mieko Tsuji, Daiki Ozaki, Nina Shibata, Yoshinobu Hashizume, Masaaki Suzuki, Hirotaka Onoe, Yasuyoshi Watanabe, Hisashi Doi. Synthesis of L-[5-11 C]Leucine and L-α-[5-11 C]Methylleucine via Pd0 -mediated 11 C-Methylation and Microfluidic Hydrogenation: Potentiality of Leucine PET Probes for Tumor Imaging.
ChemMedChem.
2021 11; 16(21):3271-3279. doi:
10.1002/cmdc.202100255. [PMID: 34128324] - Berend van der Wildt, Madina Nezam, Esther J M Kooijman, Samantha T Reyes, Bin Shen, Albert D Windhorst, Frederick T Chin. Evaluation of carbon-11 labeled 5-(1-methyl-1H-pyrazol-4-yl)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)nicotinamide as PET tracer for imaging of CSF-1R expression in the brain.
Bioorganic & medicinal chemistry.
2021 07; 42(?):116245. doi:
10.1016/j.bmc.2021.116245. [PMID: 34119698] - Hemda Schmilovitz-Weiss, Doron Boltin, David Groshar, Liran Domachevsky, Eli Rosenbaum, Nidal Issa, Boris Sapoznikov, Idan Goren, Assaf Issachar, Michal Cohen-Naftaly, Avraham Weiss, Rachel Gingold-Belfer, Hanna Bernstine. [¹¹C] choline as a potential PET/CT biomarker of liver cirrhosis: A prospective pilot study.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.
2021 06; 53(6):753-759. doi:
10.1016/j.dld.2020.11.013. [PMID: 33272861] - Yasuyoshi Watanabe, Aya Mawatari, Kazuki Aita, Yuzuru Sato, Yasuhiro Wada, Takayoshi Nakaoka, Kayo Onoe, Emi Yamano, Go Akamatsu, Akihito Ohnishi, Keiji Shimizu, Masahiro Sasaki, Hisashi Doi, Michio Senda. PET imaging of 11C-labeled thiamine tetrahydrofurfuryl disulfide, vitamin B1 derivative: First-in-human study.
Biochemical and biophysical research communications.
2021 05; 555(?):7-12. doi:
10.1016/j.bbrc.2021.03.119. [PMID: 33812058] - Amanda J Boyle, Junchao Tong, Sami S Zoghbi, Victor W Pike, Robert B Innis, Neil Vasdev. Repurposing 11C-PS13 for PET Imaging of Cyclooxygenase-1 in Ovarian Cancer Xenograft Mouse Models.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
2021 05; 62(5):665-668. doi:
10.2967/jnumed.120.249367. [PMID: 32978284] - Martin Bauer, Sandra Barna, Matthias Blaickner, Konstantin Prosenz, Karsten Bamminger, Verena Pichler, Nicolas Tournier, Marcus Hacker, Markus Zeitlinger, Georgios Karanikas, Oliver Langer. Human Biodistribution and Radiation Dosimetry of the P-Glycoprotein Radiotracer [11C]Metoclopramide.
Molecular imaging and biology.
2021 04; 23(2):180-185. doi:
10.1007/s11307-021-01582-4. [PMID: 33481175] - Ishan Garg, Mark A Nathan, Ann T Packard, Eugene D Kwon, Nicholas B Larson, Val Lowe, Brian J Davis, Rimki Haloi, Mindie L Mahon, Ajit H Goenka. 11C-choline positron emission tomography/computed tomography for detection of disease relapse in patients with history of biochemically recurrent prostate cancer and prostate-specific antigen ≤0.1 ng/ml.
Journal of cancer research and therapeutics.
2021 Apr; 17(2):358-365. doi:
10.4103/jcrt.jcrt_373_19. [PMID: 33063697] - Thomas R Hayes, Chih-Kai Chao, Joseph E Blecha, Tony L Huynh, Kurt R Zinn, Charles M Thompson, John M Gerdes, Henry F VanBrocklin. Biological Distribution and Metabolic Profiles of Carbon-11 and Fluorine-18 Tracers of VX- and Sarin-Analogs in Sprague-Dawley Rats.
Chemical research in toxicology.
2021 01; 34(1):63-69. doi:
10.1021/acs.chemrestox.0c00237. [PMID: 33373198] - Mai Hatano, Tomoyuki Miyazaki, Yoshinobu Ishiwata, Waki Nakajima, Tetsu Arisawa, Yoko Kuroki, Ayako Kobayashi, Yuuki Takada, Matsuyoshi Ogawa, Kazunori Kawamura, Ming-Rong Zhang, Makoto Higuchi, Masataka Taguri, Yasuyuki Kimura, Takuya Takahashi. Biodistribution and radiation dosimetry of the positron emission tomography probe for AMPA receptor, [11C]K-2, in healthy human subjects.
Scientific reports.
2021 01; 11(1):1598. doi:
10.1038/s41598-021-81002-3. [PMID: 33452361] - Heitor Evangelista, César Amaral, Luís Cristóvão Porto, Sérgio J Gonçalves Junior, Eduardo Delfino Sodré, Juliana Nogueira, Angela M G Dos Santos, Marcio Cataldo, Daniel Junger. Modeling the initial phase of SARS-CoV-2 deposition in the respiratory tract mimicked by the 11C radionuclide.
PloS one.
2021; 16(1):e0245019. doi:
10.1371/journal.pone.0245019. [PMID: 33444356] - Lin Qiu, Lixia Du, Qianwa Liang, Hongzhen Hu, Zhude Tu. Synthesis and in vitro evaluation of new TRPV4 ligands and biodistribution study of an 11C-labeled radiotracer in rodents.
Bioorganic & medicinal chemistry letters.
2020 11; 30(22):127573. doi:
10.1016/j.bmcl.2020.127573. [PMID: 32980513] - Jörg Mauler, Alexander Heinzel, Andreas Matusch, Hans Herzog, Irene Neuner, Jürgen Scheins, Christine Wyss, Jürgen Dammers, Markus Lang, Johannes Ermert, Bernd Neumaier, Karl-Josef Langen, N Jon Shah. Bolus infusion scheme for the adjustment of steady state [11C]Flumazenil levels in the grey matter and in the blood plasma for neuroreceptor imaging.
NeuroImage.
2020 11; 221(?):117160. doi:
10.1016/j.neuroimage.2020.117160. [PMID: 32679251] - Silvi Telo, Stefano Fanti, Cristina Nanni, Alessandro Lambertini, Maria Picchio, Luigi Gianolli, Riccardo Schiavina, Lorenzo Bianchi, Alberto Briganti, Paola Mapelli, Paolo Castellucci, Andrea Farolfi. Negative 11C-choline PET/computed tomography imaging in restaging of patients with prostate cancer with serum prostate-specific antigen values >20 ng/mL.
Nuclear medicine communications.
2020 Nov; 41(11):1178-1182. doi:
10.1097/mnm.0000000000001266. [PMID: 32804916] - Anna H Boerwinkle, Jeremy F Strain, Tricia Burdo, John Doyle, Jon Christensen, Yi Su, Julie K Wisch, Sarah A Cooley, Florin Vaida, Mandy D Smith, Hussain Jafri, Robert H Paul, Tammie L S Benzinger, Beau M Ances. Comparison of [11C]-PBR28 Binding Between Persons Living With HIV and HIV-Uninfected Individuals.
Journal of acquired immune deficiency syndromes (1999).
2020 10; 85(2):244-251. doi:
10.1097/qai.0000000000002435. [PMID: 32658129] - Elisa Schmidt, Christian Schinke, Michael Rullmann, Julia Luthardt, Georg-Alexander Becker, Sarah Haars, Muriel Stoppe, Donald Lobsien, Karl-Titus Hoffmann, Osama Sabri, Swen Hesse, Florian Then Bergh. Changes of central noradrenaline transporter availability in immunotherapy-naïve multiple sclerosis patients.
Scientific reports.
2020 09; 10(1):14651. doi:
10.1038/s41598-020-70732-5. [PMID: 32887904] - Daniele Bertoglio, Jeroen Verhaeghe, Špela Korat, Alan Miranda, Leonie Wyffels, Sigrid Stroobants, Ladislav Mrzljak, Celia Dominguez, Longbin Liu, Mette Skinbjerg, Ignacio Munoz-Sanjuan, Steven Staelens. In vitro and In vivo Assessment of Suitable Reference Region and Kinetic Modelling for the mGluR1 Radioligand [11C]ITDM in Mice.
Molecular imaging and biology.
2020 08; 22(4):854-863. doi:
10.1007/s11307-019-01435-1. [PMID: 31792838] - Aya Ogata, Yasuyuki Kimura, Hiroshi Ikenuma, Takashi Yamada, Junichiro Abe, Hiroko Koyama, Masaaki Suzuki, Masanori Ichise, Takashi Kato, Kengo Ito. Brain pharmacokinetics and biodistribution of 11C-labeled isoproterenol in rodents.
Nuclear medicine and biology.
2020 Jul; 86-87(?):52-58. doi:
10.1016/j.nucmedbio.2020.06.002. [PMID: 32532591] - Viktoria Zoufal, Severin Mairinger, Mirjam Brackhan, Markus Krohn, Thomas Filip, Michael Sauberer, Johann Stanek, Thomas Wanek, Nicolas Tournier, Martin Bauer, Jens Pahnke, Oliver Langer. Imaging P-Glycoprotein Induction at the Blood-Brain Barrier of a β-Amyloidosis Mouse Model with 11C-Metoclopramide PET.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
2020 07; 61(7):1050-1057. doi:
10.2967/jnumed.119.237198. [PMID: 31806767] - Laura M Best, Belinda Williams, Bernard Le Foll, Esmaeil Mansouri, Richard P Bazinet, Lin Lin, Vincenzo De Luca, Dina Lagzdins, Pablo Rusjan, Rachel F Tyndale, Alan A Wilson, Christian S Hendershot, Markus Heilig, Sylvain Houle, Junchao Tong, Stephen J Kish, Isabelle Boileau. Lower brain fatty acid amide hydrolase in treatment-seeking patients with alcohol use disorder: a positron emission tomography study with [C-11]CURB.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.
2020 07; 45(8):1289-1296. doi:
10.1038/s41386-020-0606-2. [PMID: 31910433] - Yong-Gen Yin, Nobuo Suzui, Keisuke Kurita, Yuta Miyoshi, Yusuke Unno, Shu Fujimaki, Takuji Nakamura, Takuro Shinano, Naoki Kawachi. Visualising spatio-temporal distributions of assimilated carbon translocation and release in root systems of leguminous plants.
Scientific reports.
2020 06; 10(1):8446. doi:
10.1038/s41598-020-65668-9. [PMID: 32528026] - Mohammad Mahdi Moein, Miklós Tóth, Lenke Tari, Andrea Varrone, Mohamed Abdel-Rehim, Christer Halldin. New approach in radiometabolite analysis of positron emission tomography (PET) radioligands; lead-shielded microextraction by packed sorbent as a tool for in vivo radiometabolite analysis of [11C]SMW139 in rat plasma.
Talanta.
2020 Feb; 208(?):120449. doi:
10.1016/j.talanta.2019.120449. [PMID: 31816716] - Zude Chen, Xiashuang Wang, Yulong Xu, Changning Wang. Synthesis of 11C-labeled DNA polymerase-β inhibitor 5-methoxyflavone and PET/CT imaging thereof.
Nuclear medicine and biology.
2019 Nov; 78-79(?):17-22. doi:
10.1016/j.nucmedbio.2019.10.005. [PMID: 31678783] - Gabrielle Normand, Sandrine Lemoine, Didier Le Bars, Ines Merida, Zacharie Irace, Thomas Troalen, Nicolas Costes, Laurent Juillard. PET [11C]acetate is also a perfusion tracer for kidney evaluation purposes.
Nuclear medicine and biology.
2019 Sep; 76-77(?):10-14. doi:
10.1016/j.nucmedbio.2019.08.004. [PMID: 31675615] - Constantin Lapa, Malte Kircher, Matteo Da Via, Martin Schreder, Leo Rasche, K Martin Kortüm, Hermann Einsele, Andreas K Buck, Heribert Hänscheid, Samuel Samnick. Comparison of 11C-Choline and 11C-Methionine PET/CT in Multiple Myeloma.
Clinical nuclear medicine.
2019 Aug; 44(8):620-624. doi:
10.1097/rlu.0000000000002638. [PMID: 31274607] - Jasper van der Aart, Maqsood Yaqub, Esther J M Kooijman, Jaco Bakker, Jan A M Langermans, Robert C Schuit, Mark B M Hofman, Johannes A M Christiaans, Adriaan A Lammertsma, Albert D Windhorst, Bart N M van Berckel. Evaluation of the Novel PET Tracer [11C]HACH242 for Imaging the GluN2B NMDA Receptor in Non-Human Primates.
Molecular imaging and biology.
2019 08; 21(4):676-685. doi:
10.1007/s11307-018-1284-x. [PMID: 30306318] - Kazuhiro Kitajima, Shingo Yamamoto, Yukako Nakanishi, Yusuke Yamada, Takahiko Hashimoto, Toru Suzuki, Shuken Go, Akihiro Kanematsu, Michio Nojima, Masayuki Fujiwara, Hayato Kaida, Masakatsu Tsurusaki, Tomonori Kanda, Yukihisa Tamaki, Koichiro Yamakado. Evaluation of Treatment Response in Prostate Cancer and Renal Cell Carcinoma Patients Using 11C-choline PET/CT Findings.
Acta medica Okayama.
2019 Aug; 73(4):341-347. doi:
10.18926/amo/56936. [PMID: 31439957] - Diego A Pizzagalli, Sabina Berretta, Dustin Wooten, Franziska Goer, Kanoelani T Pilobello, Poornima Kumar, Laura Murray, Miranda Beltzer, Anne Boyer-Boiteau, Nathanial Alpert, Georges El Fakhri, Naguib Mechawar, Gordana Vitaliano, Gustavo Turecki, Marc Normandin. Assessment of Striatal Dopamine Transporter Binding in Individuals With Major Depressive Disorder: In Vivo Positron Emission Tomography and Postmortem Evidence.
JAMA psychiatry.
2019 08; 76(8):854-861. doi:
10.1001/jamapsychiatry.2019.0801. [PMID: 31042280] - Nicolas Tournier, Martin Bauer, Verena Pichler, Lukas Nics, Eva-Maria Klebermass, Karsten Bamminger, Peter Matzneller, Maria Weber, Rudolf Karch, Fabien Caillé, Sylvain Auvity, Solène Marie, Walter Jäger, Wolfgang Wadsak, Marcus Hacker, Markus Zeitlinger, Oliver Langer. Impact of P-Glycoprotein Function on the Brain Kinetics of the Weak Substrate 11C-Metoclopramide Assessed with PET Imaging in Humans.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
2019 07; 60(7):985-991. doi:
10.2967/jnumed.118.219972. [PMID: 30630940] - Akihiro Takano, Sangram Nag, Zhisheng Jia, Mahabuba Jahan, Anton Forsberg, Ryosuke Arakawa, Per Grybäck, Guillaume Duvey, Christer Halldin, Delphine Charvin. Characterization of [11C]PXT012253 as a PET Radioligand for mGlu4 Allosteric Modulators in Nonhuman Primates.
Molecular imaging and biology.
2019 06; 21(3):500-508. doi:
10.1007/s11307-018-1257-0. [PMID: 30066121] - Sjoerd J Finnema, Samantha Rossano, Mika Naganawa, Shannan Henry, Hong Gao, Richard Pracitto, Ralph P Maguire, Joël Mercier, Sophie Kervyn, Jean-Marie Nicolas, Henrik Klitgaard, Steven DeBruyn, Christian Otoul, Paul Martin, Pierandrea Muglia, David Matuskey, Nabeel B Nabulsi, Yiyun Huang, Rafal M Kaminski, Jonas Hannestad, Armel Stockis, Richard E Carson. A single-center, open-label positron emission tomography study to evaluate brivaracetam and levetiracetam synaptic vesicle glycoprotein 2A binding in healthy volunteers.
Epilepsia.
2019 05; 60(5):958-967. doi:
10.1111/epi.14701. [PMID: 30924924] - Roni Nielsen, Niels Møller, Lars C Gormsen, Lars Poulsen Tolbod, Nils Henrik Hansson, Jens Sorensen, Hendrik Johannes Harms, Jørgen Frøkiær, Hans Eiskjaer, Nichlas Riise Jespersen, Søren Mellemkjaer, Thomas Ravn Lassen, Kasper Pryds, Hans Erik Bøtker, Henrik Wiggers. Cardiovascular Effects of Treatment With the Ketone Body 3-Hydroxybutyrate in Chronic Heart Failure Patients.
Circulation.
2019 04; 139(18):2129-2141. doi:
10.1161/circulationaha.118.036459. [PMID: 30884964] - Viktoria Zoufal, Severin Mairinger, Markus Krohn, Thomas Wanek, Thomas Filip, Michael Sauberer, Johann Stanek, Alexander Traxl, John D Schuetz, Claudia Kuntner, Jens Pahnke, Oliver Langer. Influence of Multidrug Resistance-Associated Proteins on the Excretion of the ABCC1 Imaging Probe 6-Bromo-7-[11C]Methylpurine in Mice.
Molecular imaging and biology.
2019 04; 21(2):306-316. doi:
10.1007/s11307-018-1230-y. [PMID: 29942989] - Ye-Ha Jung, Hyeonjin Kim, So Yeon Jeon, Jeong Min Kwon, Won Joon Lee, Yong Chul Kim, Joon Hwan Jang, Soo-Hee Choi, Jun-Young Lee, Do-Hyung Kang. Brain Metabolites and Peripheral Biomarkers Associated with Neuroinflammation in Complex Regional Pain Syndrome Using [11C]-(R)-PK11195 Positron Emission Tomography and Magnetic Resonance Spectroscopy: A Pilot Study.
Pain medicine (Malden, Mass.).
2019 03; 20(3):504-514. doi:
10.1093/pm/pny111. [PMID: 29986072] - Chi-Lai Ho, Sirong Chen, Yim Lung Leung, Kam Chau Cheng, Yuet Hung Wong. Dual-Tracer PET/CT Differentiates 2 Types of Primary Cancers and Metastases in a Patient With Crossed Fused Renal Ectopia.
Clinical nuclear medicine.
2019 Feb; 44(2):157-158. doi:
10.1097/rlu.0000000000002390. [PMID: 30608912] - Kazuhiro Kitajima, Shingo Yamamoto, Yusuke Kawanaka, Takayuki Katsuura, Masahiro Fujita, Yukako Nakanishi, Yusuke Yamada, Takahiko Hashimoto, Toru Suzuki, Shuken Go, Akihiro Kanematsu, Michio Nojima, Koichiro Yamakado. Imaging of renal cell carcinoma in patients with acquired cystic disease of the kidney: comparison 11C-choline and FDG PET/CT with dynamic contrast-enhanced CT.
Japanese journal of radiology.
2019 Feb; 37(2):165-177. doi:
10.1007/s11604-018-0789-1. [PMID: 30377936] - Jaya Prabhakaran, Christine DeLorenzo, Francesca Zanderigo, Gitte M Knudsen, Nic Gilling, Mali Pratap, Matthew J Jorgensen, James Daunais, Jay R Kaplan, Ramin V Parsey, J John Mann, Dileep Kumar. In vivo PET Imaging of [11C]CIMBI-5, a 5-HT2AR Agonist Radiotracer in Nonhuman Primates.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques.
2019; 22(1):352-364. doi:
10.18433/jpps30329. [PMID: 31356761] - Benjamin A Babst, Richard Ferrieri, Michael Schueller. Detecting Rapid Changes in Carbon Transport and Partitioning with Carbon-11 (11C).
Methods in molecular biology (Clifton, N.J.).
2019; 2014(?):163-176. doi:
10.1007/978-1-4939-9562-2_14. [PMID: 31197795] - Assunta Carpinelli, Paolo Rainone, Sara Belloli, Annalisa Reale, Andrea Cappelli, Giuliani Germano, Valentina Murtaj, Angela Coliva, Giuseppe Di Grigoli, Angela Valeri, Maria Carla Gilardi, Luigi Gianolli, Maurizio Anzini, Rosa Maria Moresco. Radiosynthesis and Preclinical Evaluation of 11C-VA426, a Cyclooxygenase-2 Selective Ligand.
Contrast media & molecular imaging.
2019; 2019(?):5823261. doi:
10.1155/2019/5823261. [PMID: 31598112] - Kiel D Neumann, Joseph E Blecha, Thomas R Hayes, Tony Huynh, Chih-Kai Chao, Nicolas Guilloteau, Kurt R Zinn, Henry F VanBrocklin, Charles M Thompson, John M Gerdes. Radiosynthesis, ex Vivo Biodistribution, and in Vivo Positron Emission Tomography Imaging Evaluations of [11C]2-Pyridinealdoxime Methiodide ([11C]2-PAM): A First-In-Class Antidote Tracer for Organophosphate Intoxication.
ACS chemical neuroscience.
2018 12; 9(12):3007-3014. doi:
10.1021/acschemneuro.8b00212. [PMID: 30071719] - J S Dileep Kumar, Francesca Zanderigo, Jaya Prabhakaran, Harry Rubin-Falcone, Ramin V Parsey, J John Mann. In vivo evaluation of [11C]TMI, a COX-2 selective PET tracer, in baboons.
Bioorganic & medicinal chemistry letters.
2018 12; 28(23-24):3592-3595. doi:
10.1016/j.bmcl.2018.10.049. [PMID: 30396759] - Elizabeth W Tucker, Beatriz Guglieri-Lopez, Alvaro A Ordonez, Brittaney Ritchie, Mariah H Klunk, Richa Sharma, Yong S Chang, Julian Sanchez-Bautista, Sarah Frey, Martin A Lodge, Steven P Rowe, Daniel P Holt, Jogarao V S Gobburu, Charles A Peloquin, William B Mathews, Robert F Dannals, Carlos A Pardo, Sujatha Kannan, Vijay D Ivaturi, Sanjay K Jain. Noninvasive 11C-rifampin positron emission tomography reveals drug biodistribution in tuberculous meningitis.
Science translational medicine.
2018 12; 10(470):. doi:
10.1126/scitranslmed.aau0965. [PMID: 30518610] - Yukako Nakanishi, Kazuhiro Kitajima, Yusuke Yamada, Takahiko Hashimoto, Toru Suzuki, Shuken Go, Akihiro Kanematsu, Michio Nojima, Koichiro Yamakado, Shingo Yamamoto. Diagnostic performance of 11C-choline PET/CT and FDG PET/CT for staging and restaging of renal cell cancer.
Annals of nuclear medicine.
2018 Dec; 32(10):658-668. doi:
10.1007/s12149-018-1287-3. [PMID: 30120698] - Dean F Wong, Robert A Comley, Hiroto Kuwabara, Paul B Rosenberg, Susan M Resnick, Susanne Ostrowitzki, Cristina Vozzi, Frank Boess, Esther Oh, Constantine G Lyketsos, Michael Honer, Luca Gobbi, Gregory Klein, Noble George, Lorena Gapasin, Kelly Kitzmiller, Josh Roberts, Jeff Sevigny, Ayon Nandi, James Brasic, Chakradhar Mishra, Madhav Thambisetty, Abhay Mogekar, Anil Mathur, Marilyn Albert, Robert F Dannals, Edilio Borroni. Characterization of 3 Novel Tau Radiopharmaceuticals, 11C-RO-963, 11C-RO-643, and 18F-RO-948, in Healthy Controls and in Alzheimer Subjects.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
2018 12; 59(12):1869-1876. doi:
10.2967/jnumed.118.209916. [PMID: 29728519] - Andrew G Cairns, Ana Vazquez-Romero, Mohammad Mahdi Moein, Jörgen Ådén, Charles S Elmore, Akihiro Takano, Ryosuke Arakawa, Andrea Varrone, Fredrik Almqvist, Magnus Schou. Increased Brain Exposure of an Alpha-Synuclein Fibrillization Modulator by Utilization of an Activated Ester Prodrug Strategy.
ACS chemical neuroscience.
2018 11; 9(11):2542-2547. doi:
10.1021/acschemneuro.8b00236. [PMID: 29901990] - Stal Shrestha, Prachi Singh, Michelle Y Cortes-Salva, Kimberly J Jenko, Masamichi Ikawa, Min-Jeong Kim, Masato Kobayashi, Cheryl L Morse, Robert L Gladding, Jeih-San Liow, Sami S Zoghbi, Masahiro Fujita, Robert B Innis, Victor W Pike. 3-Substituted 1,5-Diaryl-1 H-1,2,4-triazoles as Prospective PET Radioligands for Imaging Brain COX-1 in Monkey. Part 2: Selection and Evaluation of [11C]PS13 for Quantitative Imaging.
ACS chemical neuroscience.
2018 11; 9(11):2620-2627. doi:
10.1021/acschemneuro.8b00103. [PMID: 29792035] - Aleksandra Pekošak, Janez Ž Bulc, Špela Korat, Robert C Schuit, Esther Kooijman, Ricardo Vos, Marissa Rongen, Mariska Verlaan, Kevin Takkenkamp, Wissam Beaino, Alex J Poot, Albert D Windhorst. Synthesis and Preclinical Evaluation of the First Carbon-11 Labeled PET Tracers Targeting Substance P1-7.
Molecular pharmaceutics.
2018 11; 15(11):4872-4883. doi:
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Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
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