16-Hydroxyprogesterone (BioDeep_00000846512)
代谢物信息卡片
化学式: C21H30O3 (330.2195)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(=O)C1C(CC2C1(CCC3C2CCC4=CC(=O)CCC34C)C)O
InChI: InChI=1S/C21H30O3/c1-12(22)19-18(24)11-17-15-5-4-13-10-14(23)6-8-20(13,2)16(15)7-9-21(17,19)3/h10,15-19,24H,4-9,11H2,1-3H3/t15-,16+,17+,18?,19+,20+,21+/m1/s1
描述信息
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
同义名列表
1 个代谢物同义名
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Karl-Heinz Storbeck, Pieter Swart, Donita Africander, Riaan Conradie, Renate Louw, Amanda C Swart. 16α-hydroxyprogesterone: origin, biosynthesis and receptor interaction.
Molecular and cellular endocrinology.
2011 Apr; 336(1-2):92-101. doi:
10.1016/j.mce.2010.11.016. [PMID: 21095220] - Sofia Christakoudi, David A Cowan, Norman F Taylor. Steroids excreted in urine by neonates with 21-hydroxylase deficiency: characterization, using GC-MS and GC-MS/MS, of the D-ring and side chain structure of pregnanes and pregnenes.
Steroids.
2010 Jan; 75(1):34-52. doi:
10.1016/j.steroids.2009.09.011. [PMID: 19799922] - P Swart, A C Swart, M R Waterman, R W Estabrook, J I Mason. Progesterone 16 alpha-hydroxylase activity is catalyzed by human cytochrome P450 17 alpha-hydroxylase.
The Journal of clinical endocrinology and metabolism.
1993 Jul; 77(1):98-102. doi:
10.1210/jcem.77.1.8325965. [PMID: 8325965] - S Maruyama, T Suzuki, T Yanaihara, H Araki, T Nakayawa. [C21-steroid profiles in pregnancy associated with intrauterine growth retardation].
Nihon Sanka Fujinka Gakkai zasshi.
1986 Apr; 38(4):513-9. doi:
. [PMID: 3701142] - T L Glass, J Winter, V D Bokkenheuser, P B Hylemon. Biotransformation of 16 alpha-hydroxyprogesterone by Eubacterium sp. 144: non-enzymatic addition of L-cysteine to delta 16-progesterone.
Journal of lipid research.
1982 Feb; 23(2):352-6. doi:
10.1016/s0022-2275(20)38166-9. [PMID: 7077150] - V D Bokkenheuser, J Winter, P B Hylemon, N K Ayengar, E H Mosbach. Dehydroxylation of 16 alpha-hydroxyprogesterone by fecal flora of man and rat.
Journal of lipid research.
1981 Jan; 22(1):95-102. doi:
. [PMID: 7217789] - J E Buster, P J Meis, C J Hobel, J R Marshall. Subhourly variability of circulating third trimester maternal steroid concentrations as a source of sampling error.
The Journal of clinical endocrinology and metabolism.
1978 Jun; 46(6):907-10. doi:
10.1210/jcem-46-6-907. [PMID: 263471]
