Eremophilane (BioDeep_00000846509)
natural product
代谢物信息卡片
Eremophilane
化学式: C15H28 (208.2190888)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(C)[C@@H]1CC[C@H]2CCC[C@H](C)[C@@]2(C)C1
InChI: InChI=1S/C15H28/c1-11(2)13-8-9-14-7-5-6-12(3)15(14,4)10-13/h11-14H,5-10H2,1-4H3/t12-,13+,14+,15+/m0/s1
数据库引用编号
5 个数据库交叉引用编号
- ChEBI: CHEBI:36521
- PubChem: 9548704
- MeSH: Polycyclic Sesquiterpenes
- CAS: 3242-05-5
- LOTUS: LTS0128576
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
4 个相关的物种来源信息
- 4210 - Asteraceae: LTS0128576
- 3398 - Magnoliopsida: LTS0128576
- 18794 - Senecio: LTS0128576
- 58023 - Tracheophyta: LTS0128576
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Xin-Yi Wei, Hong-Bing Sun, Rui-Ying Xi, Fan Wu, Yi-Lin Liu, Zhuo-Lin Jin, Da-Le Guo, Bing Xia, Fei Wang, Yan Zhou. New eremophilane-type sesquiterpenes from Synotis solidaginea.
Fitoterapia.
2024 Jun; 175(?):105970. doi:
10.1016/j.fitote.2024.105970. [PMID: 38653340] - Jaie Karve, Chhaya Gadgoli. Chemical composition and anti-angiogenic activity of the essential oil from Blumea eriantha D.C.
Natural product research.
2024 Jun; 38(11):1918-1923. doi:
10.1080/14786419.2023.2227990. [PMID: 38739564] - Xiang-Da Li, Yan-Gang Cao, Yu-Han Zhang, Ying-Jie Ren, Meng-Nan Zeng, Yan-Ling Liu, Xu Chen, Xin-Yi Ma, Bing-Xian Zhao, Xiao-Ke Zheng, Wei-Sheng Feng. Five new eremophilane-type sesquiterpenes from the fresh roots of Rehmannia glutinosa.
Fitoterapia.
2024 Jun; 175(?):105960. doi:
10.1016/j.fitote.2024.105960. [PMID: 38621426] - Xiaohong Li, Lin Liu, Jin Chu, Guo Wei, Jiaxue Li, Xu Sun, Honghong Fan. Functional characterization of terpene synthases SmTPS1 involved in floral scent formation in Salvia miltiorrhiza.
Phytochemistry.
2024 May; 221(?):114045. doi:
10.1016/j.phytochem.2024.114045. [PMID: 38460781] - Jing-Wen Wang, Dong-Yun Liu, Hou-Ze Zhang, Zhen Tan, Cai-Juan Zheng, Guang-Ying Chen, Xu-Hua Nong. Drimane-type sesquiterpenoids and their anti-inflammatory evaluation from Pyrrhoderma noxium HNNU0524.
Natural product research.
2024 May; 38(10):1711-1718. doi:
10.1080/14786419.2023.2218008. [PMID: 37259794] - Suelen C Lima, André C de Oliveira, Claudia P S Tavares, Maria Luiza L Costa, Rosemary A Roque. Essential oil from Piper tuberculatum Jacq. (Piperaceae) and its majority compound β-caryophyllene: mechanism of larvicidal action against Aedes aegypti (Diptera: Culicidae) and selective toxicity.
Environmental science and pollution research international.
2024 May; 31(23):33454-33463. doi:
10.1007/s11356-024-33416-5. [PMID: 38684608] - Jingjing Sun, Anni Li, Shungang Jiao, Changxin Liu, Zefeng Zhang, Hongying Chen, Yana Liang, Xiaoli Gao, Lan Cao, Changcai Bai, Xingyun Chai. Dimeric eremophilane-type sesquiterpenoids from the peeled stems of Syringa pinnatifolia.
Phytochemistry.
2024 May; 221(?):114048. doi:
10.1016/j.phytochem.2024.114048. [PMID: 38447597] - Amner Muñoz-Acevedo, María C González, Jesús E Alonso, Karen C Flórez. The Repellent Capacity against Sitophilus zeamais (Coleoptera: Curculionidae) and In Vitro Inhibition of the Acetylcholinesterase Enzyme of 11 Essential Oils from Six Plants of the Caribbean Region of Colombia.
Molecules (Basel, Switzerland).
2024 Apr; 29(8):. doi:
10.3390/molecules29081753. [PMID: 38675573] - Zehui He, Yongtai Zhang, Zhenda Liu, Teng Guo, Xinyi Ai, Yuanzhi He, Xiaolin Hou, Nianping Feng. Synergistic treatment of androgenetic alopecia with follicular co-delivery of minoxidil and cedrol in metal-organic frameworks stabilized by covalently cross-linked cyclodextrins.
International journal of pharmaceutics.
2024 Apr; 654(?):123948. doi:
10.1016/j.ijpharm.2024.123948. [PMID: 38417724] - Cristina Campos Carraro, Patrick Turck, Alan Bahr, Luiza Donatti, Giana Corssac, Denise Lacerda, Alex Sander da Rosa Araujo, Alexandre Luz de Castro, Letícia Koester, Adriane Belló-Klein. Effect of free and nanoemulsified β-caryophyllene on monocrotaline-induced pulmonary arterial hypertension.
Biochimica et biophysica acta. Molecular cell research.
2024 Apr; 1871(4):119704. doi:
10.1016/j.bbamcr.2024.119704. [PMID: 38462075] - Amna Parveen, Muhammad Ghazanfar Abbas, Ken Keefover-Ring, Muhammad Binyameen, Raimondas Mozūraitis, Muhammad Azeem. Chemical Composition of Essential Oils from Natural Populations of Artemisia scoparia Collected at Different Altitudes: Antibacterial, Mosquito Repellent, and Larvicidal Effects.
Molecules (Basel, Switzerland).
2024 Mar; 29(6):. doi:
10.3390/molecules29061359. [PMID: 38542997] - Deli Chen, Xudong Xu, Yun Yang, Hui Meng, Minghui Xu, Lin Dong, Guoxu Ma, Xiaopo Zhang. Discovery of Cadinane-Type Sesquiterpenoids from the Infected Stems of Hibiscus tiliaceus as Potential Agrochemical Fungicides.
Journal of agricultural and food chemistry.
2024 Feb; 72(8):4089-4099. doi:
10.1021/acs.jafc.3c08508. [PMID: 38353561] - Quan Fu, Jing Yuan, Tie-Hua Yang, Jin-Hao Su, Jing-Jing Zhang, Xue-Wen Wu, Hong-Ye Zhang, Wei-Lie Xiao, Chang-Bo Zheng, Xiao-Li Li. Protoilludane-Type and Related Nor-Sesquiterpenes from Phellinus hartigii and Their Anti-Hypertrophic Activities in Rat Cardiomyocytes.
Journal of natural products.
2024 02; 87(2):297-303. doi:
10.1021/acs.jnatprod.3c00985. [PMID: 38308643] - Meng Zhang, Huan Zhao, Jing-Wen Kong, Mei-Gu Chen, Qing Yang, Wei Xu, Dan Hu, Liang-Dong Guo, Guo-Dong Chen, Hao Gao. New sesquiterpenoids from Biscogniauxia sp.
Journal of Asian natural products research.
2024 Feb; 26(2):214-227. doi:
10.1080/10286020.2024.2314188. [PMID: 38353486] - Quan Lei, Li Xu, Kai-Yue Tang, Jie-Ling Yu, Xiao-Feng Chen, Shuang-Xiong Wu, Jin-Jun Wang, Hong-Bo Jiang. An Antenna-Enriched Chemosensory Protein Plays Important Roles in the Perception of Host Plant Volatiles in Bactrocera dorsalis (Diptera: Tephritidae).
Journal of agricultural and food chemistry.
2024 Jan; ?(?):. doi:
10.1021/acs.jafc.3c06890. [PMID: 38294413] - Qianqian Cheng, Bin Lyu, Jingweng Hu, Zhiqiang Zhang, Yusheng Huang, Zhenhua Wang. Research on the antipruritic active ingredients of Mikania micrantha.
Fitoterapia.
2024 Jan; 174(?):105837. doi:
10.1016/j.fitote.2024.105837. [PMID: 38286314] - Jesús Palá-Paúl, María José Pérez-Alonso, Ana C Soria, Joseph J Brophy. Chemical Composition of the Essential Oils of the Iberian Peninsula Endemic Species Eryngium dilatatum Lam.
Molecules (Basel, Switzerland).
2024 Jan; 29(3):. doi:
10.3390/molecules29030562. [PMID: 38338307] - Shuyuan Mo, Yaxin Zhang, Rui Jiang, Hanxiao Zeng, Zhihong Huang, Jie Yin, Sitian Zhang, Jun Yao, Jianping Wang, Zhengxi Hu, Yonghui Zhang. Dipeniroqueforins A-B and Peniroqueforin D: Eremophilane-Type Sesquiterpenoid Derivatives with Cytotoxic Activity from Penicillium roqueforti.
The Journal of organic chemistry.
2024 01; 89(2):1209-1219. doi:
10.1021/acs.joc.3c02360. [PMID: 38192075] - Ly Thi Huong Nguyen, Nhi Phuc Khanh Nguyen, Khoa Nguyen Tran, Heung-Mook Shin, In-Jun Yang. Intranasal administration of the essential oil from Perillae Folium ameliorates social defeat stress-induced behavioral impairments in mice.
Journal of ethnopharmacology.
2024 Jan; 324(?):117775. doi:
10.1016/j.jep.2024.117775. [PMID: 38224793] - Yuan-Tong Qi, Jia-Zhu Wang, Yu Zheng, Jia-Wei Zhang, Shu-Shan Du. Chemical Composition and Insecticidal Activities of Blumea balsamifera (Sambong) Essential Oil Against Three Stored Product Insects.
Journal of food protection.
2024 Jan; 87(1):100205. doi:
10.1016/j.jfp.2023.100205. [PMID: 38065366] - Ivanka Semerdjieva, Valtcho D Zheljazkov, Ivayla Dincheva, Tzenka Radoukova, Tess Astatkie, Vasilina Maneva, Dina Atanasova, Hafize Fidan, Stanko Stankov, Albena Stoyanova. Chemical profile of Juniperus excelsa M. Bieb. essential oil within and between populations and its weed seed suppression effect.
PloS one.
2024; 19(2):e0294126. doi:
10.1371/journal.pone.0294126. [PMID: 38330006] - John Staton Laws, Scott D Smid. Characterizing cannabis-prevalent terpenes for neuroprotection reveal a role for α and β-pinenes in mitigating amyloid β-evoked neurotoxicity and aggregation in vitro.
Neurotoxicology.
2024 Jan; 100(?):16-24. doi:
10.1016/j.neuro.2023.12.004. [PMID: 38070653] - Kun Chai, Shuai Chen, Pengjie Wang, Weilong Kong, Xiaokai Ma, Xingtan Zhang. Multiomics Analysis Reveals the Genetic Basis of Volatile Terpenoid Formation in Oolong Tea.
Journal of agricultural and food chemistry.
2023 Dec; 71(49):19888-19899. doi:
10.1021/acs.jafc.3c06762. [PMID: 38048088] - Sandra Regina Nunes de Andrade Medeiros, Iverson Conrado Bezerra, Artur José da Silva, Lucas Aleixo Leal Pedroza, Regildo Max Gomes Martins, Ana Maria Henrique Moniz, Ana Cristina Gonçalves Reis de Melo, Weslley Souza Paiva, Priscila Gubert, Antonio Alves de Melo Filho. In Vitro and In Silico Antioxidant Activity and Molecular Characterization of Bauhinia ungulata L. Essential Oil.
Chemistry & biodiversity.
2023 Dec; ?(?):e202301536. doi:
10.1002/cbdv.202301536. [PMID: 38090811] - Henry Struwe, Finn Schrödter, Hanke Spinck, Andreas Kirschning. Sesquiterpene Backbones Generated by Sesquiterpene Cyclases: Formation of iso-Caryolan-1-ol and an Isoclovane.
Organic letters.
2023 12; 25(48):8575-8579. doi:
10.1021/acs.orglett.3c03383. [PMID: 38011332] - Lingling Ma, Tao Wu, Peiling Liu, Dongying Chen, Shengliang Cai, Hefeng Chen, Jingtao Zhou, Chaoyi Zhu, Shuang Li. Green Production of a High-value Mosquito Insecticide of Nootkatone from Seaweed Hydrolysates.
Journal of agricultural and food chemistry.
2023 Dec; 71(48):18919-18927. doi:
10.1021/acs.jafc.3c06708. [PMID: 37991146] - Guglielmina Froldi, Francesco Benetti, Andrea Mondin, Marco Roverso, Elisa Pangrazzi, Francine Medjiofack Djeujo, Paolo Pastore. Pterodon emarginatus Seed Preparations: Antiradical Activity, Chemical Characterization, and In Silico ADMET Parameters of β-caryophyllene and Farnesol.
Molecules (Basel, Switzerland).
2023 Nov; 28(22):. doi:
10.3390/molecules28227494. [PMID: 38005216] - Jie Dong, Mi Zhou, Da-Bo Pan, Qian-Yu Qin, Ting Li, Xin-Sheng Yao, Hai-Bo Li, Yang Yu. Eremophilane and cadinane sesquiterpenoids from the fruits of Alpinia oxyphylla and their anti-inflammatory activities.
Food & function.
2023 Oct; 14(21):9755-9766. doi:
10.1039/d3fo01221b. [PMID: 37830383] - Xuefei Chang, Yating Guo, Yujia Xie, Yijia Ren, Yaluan Bi, Fang Wang, Qi Fang, Gongyin Ye. Rice volatile compound (E)-β-caryophyllene induced by rice dwarf virus (RDV) attracts the natural enemy Cyrtorhinus lividipennis to prey on RDV insect vectors.
Pest management science.
2023 Oct; ?(?):. doi:
10.1002/ps.7822. [PMID: 37814777] - Ming Zhou, Jia Zhou, Xiaogang Peng, Fangfang Duan, Ying Gao, Xianggao Meng, Hanli Ruan. Isomeric eremophilane lactones from the whole plant of Parasenecio albus and their cytotoxic and immunosuppressive activities.
Phytochemistry.
2023 Oct; 214(?):113821. doi:
10.1016/j.phytochem.2023.113821. [PMID: 37567352] - Yu-Wen Fan, Wei-Jie Zhang, Zhuo-Yi Ao, Jia-Yan Chen, Xin Lian, Yong-Chen Pan, Li-Ping Chen, Dong-Xu Jiang, Jie-Wei Wu. Four new eudesmane-type and one new eremophilane-type sesquiterpenes from the whole plant of Carpesium abrotanoides L.
Fitoterapia.
2023 Sep; 169(?):105548. doi:
10.1016/j.fitote.2023.105548. [PMID: 37236512] - Riham A El-Shiekh, Hanaa A H Kassem, Amal E Khaleel, Menna M A Abd El-Mageed. Anticholinesterases activity of Murraya koenigii (L.) Spreng. and Murraya paniculata (L.) Jacq. essential oils with GC/MS analysis and molecular docking.
Natural product research.
2023 Jul; ?(?):1-5. doi:
10.1080/14786419.2023.2241150. [PMID: 37516925] - Bian-Xia Xue, Tian-Tian Yang, Ru-Shang He, Wen-Ke Gao, Jia-Xin Lai, Si-Xia Liu, Cong-Yan Duan, Shao-Xia Wang, Hui-Juan Yu, Wen-Zhi Yang, Li-Hua Zhang, Qi-Long Wang, Hong-Hua Wu. Degradation Profiling of Nardosinone at High Temperature and in Simulated Gastric and Intestinal Fluids.
Molecules (Basel, Switzerland).
2023 Jul; 28(14):. doi:
10.3390/molecules28145382. [PMID: 37513256] - Tuan Quoc Doan, Dien Dinh, Thang Nam Tran, Phu Quynh Dinh Nguyen, Chau Bao Hoai Nguyen, Nhan Trong Le, Hung Quoc Vo, Duc Viet Ho, Anh Le Tuan, Hoai Thi Nguyen, Isiaka A Ogunwande. Chemical composition and acetylcholinesterase inhibitory activity of essential oil from the leaves of Mitrephora poilanei Weeras. & R.M.K. Saunders.
Natural product research.
2023 Jun; ?(?):1-5. doi:
10.1080/14786419.2023.2227989. [PMID: 37357615] - Diep Trinh Thi, Dung Luong Van, Trung Phung Van, Hoai Nguyen Thi, Thao Do Thi, Uyen Nguyen Thi To, Linh Tran Thi Hoai, Khai Dang Vinh, Thanh Truc Huynh, Tran Le Thi Thanh. Chemical composition, anti-inflammatory and cytotoxic activity of essential oils from two Luvunga species (L. scandens and L. hongiaoensis) from Vietnam.
Natural product research.
2023 Jun; ?(?):1-10. doi:
10.1080/14786419.2023.2225125. [PMID: 37337451] - Fapetu Kemi Busayo, Jin-Ling Yang, Xu-Po Ding, Ya-Li Wang, Cui-Juan Gai, Fei Wu, Hao-Fu Dai, Wen-Li Mei, Hui-Qin Chen. Identification of volatile compounds and their bioactivities from unpolar fraction of Alpinia oxyphylla Miq. and mining key genes of nootkatone biosynthesis.
Natural product research.
2023 Jun; ?(?):1-6. doi:
10.1080/14786419.2023.2220063. [PMID: 37278024] - Sanjeevan Rajendran, Luke P Robertson, Lakmini Kosgahakumbura, Chathurika Fernando, Ulf Göransson, Helen Wang, Chamari Hettiarachchi, Sunithi Gunasekera. Antibacterial eremophilane sesquiterpenoids from Xylaria feejeensis, an endophytic fungi of the medicinal plant Geophila repens.
Fitoterapia.
2023 Jun; 167(?):105496. doi:
10.1016/j.fitote.2023.105496. [PMID: 36990291] - Shuang Su, Xue-Qiong Yang, Ya-Bin Yang, Zhong-Tao Ding. Antifungal and antifeedant terpenoids from Paraphaeosphaeria sp. cultured by extract of host Ginkgo biloba.
Phytochemistry.
2023 Jun; 210(?):113651. doi:
10.1016/j.phytochem.2023.113651. [PMID: 36965762] - Surui Lu, Hong Deng, Chenyao Zhou, Zhengda Du, Xuena Guo, Yanfei Cheng, Xiuping He. Enhancement of β-Caryophyllene Biosynthesis in Saccharomyces cerevisiae via Synergistic Evolution of β-Caryophyllene Synthase and Engineering the Chassis.
ACS synthetic biology.
2023 May; ?(?):. doi:
10.1021/acssynbio.3c00024. [PMID: 37224386] - Jingwen Wang, Dongsheng Wang, Li Feng, Xin Li, Yuanxiang Gong, Zhe Wang, Ninghua Tan, Jing Han. Eremophilane-type and xanthanolide-type sesquiterpenes from the aerial parts of Xanthium sibiricum and their anti-inflammatory activities.
Phytochemistry.
2023 Jan; 208(?):113603. doi:
10.1016/j.phytochem.2023.113603. [PMID: 36720451] - Yan-Ting Wu, Li-Shan Zhong, Chen Huang, Yu-Ying Guo, Fu-Jun Jin, Yu-Ze Hu, Zi-Bo Zhao, Zhe Ren, Yi-Fei Wang. β-Caryophyllene Acts as a Ferroptosis Inhibitor to Ameliorate Experimental Colitis.
International journal of molecular sciences.
2022 Dec; 23(24):. doi:
10.3390/ijms232416055. [PMID: 36555694] - Nicholas John Sadgrove. Comment on Pyrrolizidine Alkaloids and Terpenes from Senecio (Asteraceae): Chemistry and Research Gaps in Africa.
Molecules (Basel, Switzerland).
2022 Dec; 27(24):. doi:
10.3390/molecules27248868. [PMID: 36558004] - Henry Blanton, Linda Yin, Joshua Duong, Khalid Benamar. Cannabidiol and Beta-Caryophyllene in Combination: A Therapeutic Functional Interaction.
International journal of molecular sciences.
2022 Dec; 23(24):. doi:
10.3390/ijms232415470. [PMID: 36555111] - Anita Yovas, W A Manjusha, Stanely Mainzen Prince Ponnian. β-caryophyllene modulates B-cell lymphoma gene-2 family genes and inhibits the intrinsic pathway of apoptosis in isoproterenol-induced myocardial infarcted rats; A molecular mechanism.
European journal of pharmacology.
2022 Oct; 932(?):175181. doi:
10.1016/j.ejphar.2022.175181. [PMID: 35988788] - János Vetter. The Norsesquiterpene Glycoside Ptaquiloside as a Poisonous, Carcinogenic Component of Certain Ferns.
Molecules (Basel, Switzerland).
2022 Oct; 27(19):. doi:
10.3390/molecules27196662. [PMID: 36235199] - Heggar Venkataramana Sudeep, Karempudi Venkatakrishna, Amritha Raj, Budanuru Reethi, Kodimule Shyamprasad. Viphyllin™, a standardized extract from black pepper seeds, mitigates intestinal inflammation, oxidative stress, and anxiety-like behavior in DSS-induced colitis mice.
Journal of food biochemistry.
2022 10; 46(10):e14306. doi:
10.1111/jfbc.14306. [PMID: 35766031] - De-Li Chen, Guo-Xu Ma, Er-Lan Yang, Yun Yang, Can-Hong Wang, Zhao-Cui Sun, Han-Qiao Liang, Xu-Dong Xu, Jian-He Wei. Cadinane-type sesquiterpenoid dimeric diastereomers hibisceusones A-C from infected stems of Hibiscus tiliaceus with cytotoxic activity against triple-negative breast cancer cells.
Bioorganic chemistry.
2022 10; 127(?):105982. doi:
10.1016/j.bioorg.2022.105982. [PMID: 35763902] - Xu Liang, Xinzhou Yang, Tongxi Zhou, Yuanren Ma, Yu Peng, Yeerlan Bahetejiang, Yuzhao Li, Jingquan Yuan. Three new cadinane-type sesquiterpenes from Eupatorium adenophorum spreng.
Natural product research.
2022 Oct; 36(19):4898-4905. doi:
10.1080/14786419.2021.1910262. [PMID: 33899621] - Heba A S El-Nashar, Mai Adel, Mohamed El-Shazly, Ibrahim S Yahia, Hamdy S El Sheshtawy, Adel A Almalki, Nehal Ibrahim. Chemical Composition, Antiaging Activities and Molecular Docking Studies of Essential Oils from Acca sellowiana (Feijoa).
Chemistry & biodiversity.
2022 Sep; 19(9):e202200272. doi:
10.1002/cbdv.202200272. [PMID: 35938449] - Ravindra Bansal, Sunil Kumar Sethy, Zareen Khan, Nasiruddin Shaikh, Kaushik Banerjee, Prasun K Mukherjee. Genetic Evidence in Favor of a Polyketide Origin of Acremeremophilanes, the Fungal 'Sesquiterpene' Metabolites.
Microbiology spectrum.
2022 08; 10(4):e0179322. doi:
10.1128/spectrum.01793-22. [PMID: 35938791] - Anni Li, Shungang Jiao, Huiming Huang, Panlong Chen, Ruifei Zhang, Guozhu Su, Jixuan Xu, Changxin Liu, Zhongdong Hu, Suyile Chen, Pengfei Tu, Xingyun Chai, Luqi Huang. Syringenes A-L: Bioactive dimeric eremophilane sesquiterpenoids from Syringa pinnatifolia.
Bioorganic chemistry.
2022 08; 125(?):105879. doi:
10.1016/j.bioorg.2022.105879. [PMID: 35636096] - Qingwen Hu, Tianrui Zuo, Ling Deng, Sha Chen, Wu Yu, Shengwei Liu, JingDong Liu, Xuan Wang, Xiaomei Fan, Zhi Dong. β-Caryophyllene suppresses ferroptosis induced by cerebral ischemia reperfusion via activation of the NRF2/HO-1 signaling pathway in MCAO/R rats.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2022 Jul; 102(?):154112. doi:
10.1016/j.phymed.2022.154112. [PMID: 35550220] - Vafa Baradaran Rahimi, Vahid Reza Askari. A mechanistic review on immunomodulatory effects of selective type two cannabinoid receptor β-caryophyllene.
BioFactors (Oxford, England).
2022 Jul; 48(4):857-882. doi:
10.1002/biof.1869. [PMID: 35648433] - Qiwen Wang, Ji-Kai Liu, Qunfei Zhao, Qing-Li He. Mechanistic investigations of hirsutene biosynthesis catalyzed by a chimeric sesquiterpene synthase from Steccherinum ochraceum.
Fungal genetics and biology : FG & B.
2022 07; 161(?):103700. doi:
10.1016/j.fgb.2022.103700. [PMID: 35504456] - Yan-Ping Liu, Xiao-Mei Yu, Ze-Hua Qiao, Bo Jiang, Lan Xie, Hao-Xuan Tang, Xiao Liang, Yan-Hui Fu. Cadinane-type sesquiterpenes with potential anti-inflammatory and anti-HIV activities from the stems and leaves of Mappianthus iodoides.
Natural product research.
2022 Jun; 36(12):3078-3084. doi:
10.1080/14786419.2021.1956921. [PMID: 34304659] - Michele Pereira Mallmann, Fernanda Kulinski Mello, Bruna Neuberger, Karine Gabriela da Costa Sobral, Michele Rechia Fighera, Luiz Fernando Freire Royes, Ana Flávia Furian, Mauro Schneider Oliveira. Beta-caryophyllene attenuates short-term recurrent seizure activity and blood-brain-barrier breakdown after pilocarpine-induced status epilepticus in rats.
Brain research.
2022 06; 1784(?):147883. doi:
10.1016/j.brainres.2022.147883. [PMID: 35300975] - Moses K Langat, Yisau Mayowa, Nicholas Sadgrove, Mohammed Danyaal, Thomas A K Prescott, Teva Kami, Sianne Schwikkard, James Barker, Martin Cheek. Multi-layered antimicrobial synergism of (E)-caryophyllene with minor compounds, tecleanatalensine B and normelicopine, from the leaves of Vepris gossweileri (I. Verd.) Mziray.
Natural product research.
2022 May; 36(10):2447-2457. doi:
10.1080/14786419.2021.1899176. [PMID: 33719772] - Ellen de Nazaré S da Cruz, Luana de Sousa Peixoto, Jamile S da Costa, Rosa Helena V Mourão, Walnice Maria O do Nascimento, José Guilherme S Maia, William N Setzer, Joyce Kelly da Silva, Pablo Luis B Figueiredo. Seasonal Variability of a Caryophyllane Chemotype Essential Oil of Eugenia patrisii Vahl Occurring in the Brazilian Amazon.
Molecules (Basel, Switzerland).
2022 Apr; 27(8):. doi:
10.3390/molecules27082417. [PMID: 35458612] - Bassem Refaat, Mohamed El-Boshy. Protective antioxidative and anti-inflammatory actions of β-caryophyllene against sulfasalazine-induced nephrotoxicity in rat.
Experimental biology and medicine (Maywood, N.J.).
2022 04; 247(8):691-699. doi:
10.1177/15353702211073804. [PMID: 35068213] - Chun-Lei Zhang, Ju Liu, Chu-Chu Xi, Yan-Gang Cao, Jing He, Shu-Cong Li, Fan Zhang, C Benjamin Naman, Zheng-Yu Cao. Cadinane Sesquiterpenoids and Their Glycosides from Alangium chinense That Inhibit Spontaneous Calcium Oscillations.
Journal of natural products.
2022 03; 85(3):599-606. doi:
10.1021/acs.jnatprod.1c00978. [PMID: 34957832] - Yucong Li, Jiahui Shao, Yansong Fu, Yu Chen, Hongzhe Wang, Zhihui Xu, Haichao Feng, Weibing Xun, Yunpeng Liu, Nan Zhang, Qirong Shen, Wei Xuan, Ruifu Zhang. The volatile cedrene from Trichoderma guizhouense modulates Arabidopsis root development through auxin transport and signalling.
Plant, cell & environment.
2022 03; 45(3):969-984. doi:
10.1111/pce.14230. [PMID: 34800291] - Yong-Yue Wang, Qiu-Rong Li, Jun Chi, Ji-Xin Li, Ling-Yi Kong, Jun Luo. Sesquiterpenoids from the leaves of Sarcandra glabra.
Chinese journal of natural medicines.
2022 Mar; 20(3):215-220. doi:
10.1016/s1875-5364(21)60102-4. [PMID: 35369966] - Changxin Liu, Shungang Jiao, Anni Li, Jixuan Xu, Xiaochun Zhou, Suyile Chen, Pengfei Tu, Luqi Huang, Xingyun Chai. Alashanoids O-S, seco-Humulane and Eremophilane Sesquiterpenoids from Syringa pinnatifolia.
Chemistry & biodiversity.
2022 Feb; 19(2):e202100917. doi:
10.1002/cbdv.202100917. [PMID: 34927799] - De-Li Chen, Mei-Ying Chen, Yong Hou, Can-Hong Wang, Zhao-Cui Sun, Yun Yang, Han-Qiao Liang, Guo-Xu Ma, Xu-Dong Xu, Jian-He Wei. Cadinane-Type Sesquiterpenoids with Cytotoxic Activity from the Infected Stems of the Semi-mangrove Hibiscus tiliaceus.
Journal of natural products.
2022 01; 85(1):127-135. doi:
10.1021/acs.jnatprod.1c00849. [PMID: 35040320] - Fatemeh Forouzanfar, Ali Mohammad Pourbagher-Shahri, Hamed Ghazavi. Evaluation of Antiarthritic and Antinociceptive Effects of Cedrol in a Rat Model of Arthritis.
Oxidative medicine and cellular longevity.
2022; 2022(?):4943965. doi:
10.1155/2022/4943965. [PMID: 35509836] - Ankush Kumar Jha, Shobhit Gairola, Sourav Kundu, Pakpi Doye, Abu Mohammad Syed, Chetan Ram, Uttam Kulhari, Naresh Kumar, Upadhyayula Suryanarayana Murty, Bidya Dhar Sahu. Biological Activities, Pharmacokinetics and Toxicity of Nootkatone: A Review.
Mini reviews in medicinal chemistry.
2022; 22(17):2244-2259. doi:
10.2174/1389557522666220214092005. [PMID: 35156582] - Lucas Fernando Sérgio Gushiken, Fernando Pereira Beserra, Maria Fernanda Hussni, Murilo Tireli Gonzaga, Victor Pena Ribeiro, Patrícia Fernanda de Souza, Jacqueline Costa Lima Campos, Taís Nader Chrysostomo Massaro, Carlos Alberto Hussni, Regina Kiomi Takahira, Priscyla Daniely Marcato, Jairo Kenupp Bastos, Cláudia Helena Pellizzon. Beta-caryophyllene as an antioxidant, anti-inflammatory and re-epithelialization activities in a rat skin wound excision model.
Oxidative medicine and cellular longevity.
2022; 2022(?):9004014. doi:
10.1155/2022/9004014. [PMID: 35154574] - Gulmira Özek, Igor A Schepetkin, Moldir Yermagambetova, Temel Özek, Liliya N Kirpotina, Shyryn S Almerekova, Saule I Abugalieva, Andrei I Khlebnikov, Mark T Quinn. Innate Immunomodulatory Activity of Cedrol, a Component of Essential Oils Isolated from Juniperus Species.
Molecules (Basel, Switzerland).
2021 Dec; 26(24):. doi:
10.3390/molecules26247644. [PMID: 34946725] - H V Sudeep, K Venkatakrishna, Amritharaj, K Gouthamchandra, B Reethi, P Naveen, H B Lingaraju, K Shyamprasad. A standardized black pepper seed extract containing β-caryophyllene improves cognitive function in scopolamine-induced amnesia model mice via regulation of brain-derived neurotrophic factor and MAPK proteins.
Journal of food biochemistry.
2021 12; 45(12):e13994. doi:
10.1111/jfbc.13994. [PMID: 34778972] - Yuchen Wang, Xiaowei Gong, Fan Li, Shasha Zuo, Minggang Li, Jiangyuan Zhao, Xiulin Han, Mengliang Wen. Optimized biosynthesis of santalenes and santalols in Saccharomyces cerevisiae.
Applied microbiology and biotechnology.
2021 Dec; 105(23):8795-8804. doi:
10.1007/s00253-021-11661-9. [PMID: 34738171] - Zhen-Miao Qin, Yong-Hui Li, Yin-Feng Tan, Hai-Long Li. Determination of nootkatone in rat plasma by LC-tandem mass spectrometry and its application in a pharmacokinetic study.
Biomedical chromatography : BMC.
2021 Dec; 35(12):e5197. doi:
10.1002/bmc.5197. [PMID: 34162012] - Anita Yovas, Stanely Mainzen Prince Ponnian. β-Caryophyllene inhibits Fas- receptor and caspase-mediated apoptosis signaling pathway and endothelial dysfunction in experimental myocardial infarction.
Journal of biochemical and molecular toxicology.
2021 Dec; 35(12):e22907. doi:
10.1002/jbt.22907. [PMID: 34816538] - Xing Huang, Yulin Huang, Chunyue Yang, Tiantian Liu, Xing Liu, Haibin Yuan. Isolation and Insecticidal Activity of Essential Oil from Artemisia lavandulaefolia DC. against Plutella xylostella.
Toxins.
2021 11; 13(12):. doi:
10.3390/toxins13120842. [PMID: 34941680] - Yan Wang, Shenting Zhou, Qian Liu, Seong-Hee Jeong, Liyan Zhu, Xiangming Yu, Xiaojian Zheng, Gongyuan Wei, Seon-Won Kim, Chonglong Wang. Metabolic Engineering of Escherichia coli for Production of α-Santalene, a Precursor of Sandalwood Oil.
Journal of agricultural and food chemistry.
2021 Nov; 69(44):13135-13142. doi:
10.1021/acs.jafc.1c05486. [PMID: 34709805] - Márcia Moraes Cascaes, Odirleny Dos Santos Carneiro, Lidiane Diniz do Nascimento, Ângelo Antônio Barbosa de Moraes, Mozaniel Santana de Oliveira, Jorddy Neves Cruz, Giselle Maria Skelding Pinheiro Guilhon, Eloisa Helena de Aguiar Andrade. Essential Oils from Annonaceae Species from Brazil: A Systematic Review of Their Phytochemistry, and Biological Activities.
International journal of molecular sciences.
2021 Nov; 22(22):. doi:
10.3390/ijms222212140. [PMID: 34830022] - Shobhit Gairola, Chetan Ram, Abu Mohammad Syed, Pakpi Doye, Uttam Kulhari, Madhav Nilakanth Mugale, Upadhyayula Suryanarayana Murty, Bidya Dhar Sahu. Nootkatone confers antifibrotic effect by regulating the TGF-β/Smad signaling pathway in mouse model of unilateral ureteral obstruction.
European journal of pharmacology.
2021 Nov; 910(?):174479. doi:
10.1016/j.ejphar.2021.174479. [PMID: 34480883] - Silvia Di Giacomo, Alessia Mariano, Marco Gullì, Caterina Fraschetti, Annabella Vitalone, Antonello Filippi, Luisa Mannina, Anna Scotto d'Abusco, Antonella Di Sotto. Role of Caryophyllane Sesquiterpenes in the Entourage Effect of Felina 32 Hemp Inflorescence Phytocomplex in Triple Negative MDA-MB-468 Breast Cancer Cells.
Molecules (Basel, Switzerland).
2021 Nov; 26(21):. doi:
10.3390/molecules26216688. [PMID: 34771097] - Xia Xu, Jiamiao Yan. β-Caryophyllene may attenuate hyperoxaluria-induced kidney dysfunction in rats by regulating stress marker KIM-1/MCP-1 and NF-κB signaling pathway.
Journal of biochemical and molecular toxicology.
2021 Nov; 35(11):e22891. doi:
10.1002/jbt.22891. [PMID: 34468068] - Chang-Mu Chen, Chen-Yu Lin, Yao-Pang Chung, Chia-Hung Liu, Kuo-Tong Huang, Siao-Syun Guan, Cheng-Tien Wu, Shing-Hwa Liu. Protective Effects of Nootkatone on Renal Inflammation, Apoptosis, and Fibrosis in a Unilateral Ureteral Obstructive Mouse Model.
Nutrients.
2021 Nov; 13(11):. doi:
10.3390/nu13113921. [PMID: 34836176] - Claudia Delgado, Gina Mendez-Callejas, Crispin Celis. Caryophyllene Oxide, the Active Compound Isolated from Leaves of Hymenaea courbaril L. (Fabaceae) with Antiproliferative and Apoptotic Effects on PC-3 Androgen-Independent Prostate Cancer Cell Line.
Molecules (Basel, Switzerland).
2021 Oct; 26(20):. doi:
10.3390/molecules26206142. [PMID: 34684723] - Jiawei Wen, Linqiu Liu, Junjun Li, Yang He. A review of nardosinone for pharmacological activities.
European journal of pharmacology.
2021 Oct; 908(?):174343. doi:
10.1016/j.ejphar.2021.174343. [PMID: 34265296] - Ming Zhou, Fangfang Duan, Ying Gao, Xiaogang Peng, Xianggao Meng, Hanli Ruan. Eremophilane sesquiterpenoids from the whole plant of Parasenecio albus with immunosuppressive activity.
Bioorganic chemistry.
2021 10; 115(?):105247. doi:
10.1016/j.bioorg.2021.105247. [PMID: 34411979] - Na Guo, Qi-Bang Shu, Peng-Yao Zhang, Jian-Jiang Fu, Yi-Li Wan, Xiao-Min Wang, Ren-Geng Shu. Six new cadinane-type sesquiterpenoids from the leaves of Chimonanthus nitens Oliv.
Fitoterapia.
2021 Oct; 154(?):105019. doi:
10.1016/j.fitote.2021.105019. [PMID: 34403777] - Wen-Xuan Li, Ping Qian, Yi-Tong Guo, Li Gu, Jessore Jurat, Yang Bai, Dong-Fang Zhang. Myrtenal and β-caryophyllene oxide screened from Liquidambaris Fructus suppress NLRP3 inflammasome components in rheumatoid arthritis.
BMC complementary medicine and therapies.
2021 Sep; 21(1):242. doi:
10.1186/s12906-021-03410-2. [PMID: 34583676] - Rajashri R Naik, Ashok K Shakya, Benedetta Ferri, Ghaleb A Oriquat, Luisa Pistelli, Nawfal A M Numan. Volatile Composition and Biological Activity of Jordanian Commercial Samples of R. coriaria L. Fruits.
Molecules (Basel, Switzerland).
2021 Sep; 26(18):. doi:
10.3390/molecules26185691. [PMID: 34577162] - Yong Zhang, Haibo Zhang, Yan Li, Muqun Wang, Feng Qian. β-Caryophyllene attenuates lipopolysaccharide-induced acute lung injury via inhibition of the MAPK signalling pathway.
The Journal of pharmacy and pharmacology.
2021 Sep; 73(10):1319-1329. doi:
10.1093/jpp/rgab074. [PMID: 34313776] - Xia Li, Jie Gao, Miaomiao Li, Hao Cui, Wei Jiang, Zong-Cai Tu, Tao Yuan. Aromatic Cadinane Sesquiterpenoids from the Fruiting Bodies of Phellinus pini Block SARS-CoV-2 Spike-ACE2 Interaction.
Journal of natural products.
2021 08; 84(8):2385-2389. doi:
10.1021/acs.jnatprod.1c00426. [PMID: 34351742] - Xiao Li, Jing-Nan Ren, Gang Fan, Lu-Lu Zhang, Si-Yi Pan. Advances on (+)-nootkatone microbial biosynthesis and its related enzymes.
Journal of industrial microbiology & biotechnology.
2021 Aug; 48(7-8):. doi:
10.1093/jimb/kuab046. [PMID: 34279658] - Xuefei Chang, Fang Wang, Qi Fang, Fei Chen, Hongwei Yao, Angharad M R Gatehouse, Gongyin Ye. Virus-induced plant volatiles mediate the olfactory behaviour of its insect vectors.
Plant, cell & environment.
2021 08; 44(8):2700-2715. doi:
10.1111/pce.14069. [PMID: 33866575] - Hebaallah Mamdouh Hashiesh, Charu Sharma, Sameer N Goyal, Bassem Sadek, Niraj Kumar Jha, Juma Al Kaabi, Shreesh Ojha. A focused review on CB2 receptor-selective pharmacological properties and therapeutic potential of β-caryophyllene, a dietary cannabinoid.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2021 Aug; 140(?):111639. doi:
10.1016/j.biopha.2021.111639. [PMID: 34091179] - Eduardo Valarezo, Génesis Gaona-Granda, Vladimir Morocho, Luis Cartuche, James Calva, Miguel Angel Meneses. Chemical Constituents of the Essential Oil from Ecuadorian Endemic Species Croton ferrugineus and Its Antimicrobial, Antioxidant and α-Glucosidase Inhibitory Activity.
Molecules (Basel, Switzerland).
2021 Jul; 26(15):. doi:
10.3390/molecules26154608. [PMID: 34361759] - Xiaoshuang Gou, Danmei Tian, Jihua Wei, Yihan Ma, Yixue Zhang, Mei Chen, Wenjuan Ding, Bin Wu, Jinshan Tang. New Drimane Sesquiterpenes and Polyketides from Marine-Derived Fungus Penicillium sp. TW58-16 and Their Anti-Inflammatory and α-Glucosidase Inhibitory Effects.
Marine drugs.
2021 Jul; 19(8):. doi:
10.3390/md19080416. [PMID: 34436259] - Jianxun Zhu, Lihong Liu, Maobo Wu, Guiyang Xia, Pengcheng Lin, Jiachen Zi. Characterization of a Sesquiterpene Synthase Catalyzing Formation of Cedrol and Two Diastereoisomers of Tricho-Acorenol from Euphorbia fischeriana.
Journal of natural products.
2021 06; 84(6):1780-1786. doi:
10.1021/acs.jnatprod.1c00126. [PMID: 34014675] - Mozaniel Santana de Oliveira, Jorddy Neves Cruz, Oberdan Oliveira Ferreira, Daniel Santiago Pereira, Natanael Santiago Pereira, Marcos Enê Chaves Oliveira, Giorgio Cristino Venturieri, Giselle Maria Skelding Pinheiro Guilhon, Antônio Pedro da Silva Souza Filho, Eloisa Helena de Aguiar Andrade. Chemical Composition of Volatile Compounds in Apis mellifera Propolis from the Northeast Region of Pará State, Brazil.
Molecules (Basel, Switzerland).
2021 Jun; 26(11):. doi:
10.3390/molecules26113462. [PMID: 34200300] - Pu Wu, Xue-Man Dong, Gao-Qian Song, Meng-Meng Wei, Can Fang, Fu-Bo Zheng, Yue-Ji Zhao, Hua-Qiu Lu, Long-Hui Cheng, Jian-Liang Zhou, Tian Xie. Bioactivity-guided discovery of quality control markers in rhizomes of Curcuma wenyujin based on spectrum-effect relationship against human lung cancer cells.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2021 Jun; 86(?):153559. doi:
10.1016/j.phymed.2021.153559. [PMID: 33857848] - Celeste de Jesus Pereira Franco, Oberdan Oliveira Ferreira, Ângelo Antônio Barbosa de Moraes, Everton Luiz Pompeu Varela, Lidiane Diniz do Nascimento, Sandro Percário, Mozaniel Santana de Oliveira, Eloisa Helena de Aguiar Andrade. Chemical Composition and Antioxidant Activity of Essential Oils from Eugenia patrisii Vahl, E. punicifolia (Kunth) DC., and Myrcia tomentosa (Aubl.) DC., Leaf of Family Myrtaceae.
Molecules (Basel, Switzerland).
2021 May; 26(11):. doi:
10.3390/molecules26113292. [PMID: 34072598] - María Fernanda Panamito, Nicole Bec, Valeria Valdivieso, Melissa Salinas, James Calva, Jorge Ramírez, Christian Larroque, Chabaco Armijos. Chemical Composition and Anticholinesterase Activity of the Essential Oil of Leaves and Flowers from the Ecuadorian Plant Lepechinia paniculata (Kunth) Epling.
Molecules (Basel, Switzerland).
2021 May; 26(11):. doi:
10.3390/molecules26113198. [PMID: 34071744] - Avinash Godara, Katy C Kao. Adaptive laboratory evolution of β-caryophyllene producing Saccharomyces cerevisiae.
Microbial cell factories.
2021 May; 20(1):106. doi:
10.1186/s12934-021-01598-z. [PMID: 34044821] - Yuqin Gou, Fangyuan Zhang, Yueli Tang, Chunxue Jiang, Ge Bai, He Xie, Min Chen, Zhihua Liao. Engineering Nootkatone Biosynthesis in Artemisia annua.
ACS synthetic biology.
2021 05; 10(5):957-963. doi:
10.1021/acssynbio.1c00016. [PMID: 33973783]