Friedelane (BioDeep_00000846359)

   

natural product


代谢物信息卡片


Friedelane

化学式: C30H52 (412.4069)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1CCCC2C1(CCC3C2(CCC4(C3(CCC5(C4CC(CC5)(C)C)C)C)C)C)C
InChI: InChI=1S/C30H52/c1-21-10-9-11-22-27(21,5)13-12-23-28(22,6)17-19-30(8)24-20-25(2,3)14-15-26(24,4)16-18-29(23,30)7/h21-24H,9-20H2,1-8H3/t21-,22+,23-,24+,26+,27+,28-,29+,30-/m0/s1

描述信息

A triterpene that is docosahydropicene substituted by 8 methyl groups at positions 2, 2, 4a, 6a, 8a, 9, 12b and 14a.

同义名列表

1 个代谢物同义名

Friedelane



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

12 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Chimène Victoire Tchamadeu Keugwa, Flaure Rosette Essoung Ehawa, Gervais Mouthé Happi, Willifred Dongmo Tekapi Tsopgni, Alain François Kamdem Waffo, Jean Claude Ndom, Jean Duplex Wansi. Three new 30-norfriedelane and a new friedelane triterpenes from the trunk bark of Caloncoba welwitschii (Oliv.) Gilg (Achariaceae). Natural product research. 2023 Feb; 37(3):468-477. doi: 10.1080/14786419.2021.1981314. [PMID: 34570603]
  • Alex Tchinda Tedonkeu, Jean-De-Dieu Tamokou, James D Simo Mpetga, Raissa Tioyem Nzogong, Irene Chinda Kengne, Xiao-Jiang Hao, Mathieu Tene. A new antimicrobial nor-friedelane-type triterpenoid and other constituents from Plectranthus glandulosus Hook. f. (Lamiaceae). Natural product research. 2022 Sep; 36(18):4587-4596. doi: 10.1080/14786419.2021.1999946. [PMID: 34727811]
  • Aristide Mfifen Munvera, Blandine Marlyse Wache Ouahouo, Pierre Mkounga, Michelle Ines Kanko Mbekou, Shehla Nuzhat, Muhammad Iqbal Choudhary, Augustin Ephrem Nkengfack. Chemical constituents from leaves and trunk bark of Rinorea oblongifolia (Violaceae). Natural product research. 2020 Jul; 34(14):2014-2021. doi: 10.1080/14786419.2019.1573230. [PMID: 30784307]
  • Mariana G Aguilar, Grasiely F Sousa, Fernanda C G Evangelista, Adriano P Sabino, Sidney A Vieira Filho, Lucienir P Duarte. Imines and lactones derived from friedelanes and their cytotoxic activity. Natural product research. 2020 Mar; 34(6):810-815. doi: 10.1080/14786419.2018.1508137. [PMID: 30388899]
  • Jiawei Zhou, Tianyuan Hu, Linhui Gao, Ping Su, Yifeng Zhang, Yujun Zhao, Shang Chen, Lichan Tu, Yadi Song, Xing Wang, Luqi Huang, Wei Gao. Friedelane-type triterpene cyclase in celastrol biosynthesis from Tripterygium wilfordii and its application for triterpenes biosynthesis in yeast. The New phytologist. 2019 07; 223(2):722-735. doi: 10.1111/nph.15809. [PMID: 30895623]
  • You-Min Ying, Cui-Yu Li, Yan Chen, Jia-Gui Xiang, Ling Fang, Jian-Biao Yao, Fa-Song Wang, Ru-Wei Wang, Wei-Guang Shan, Zha-Jun Zhan. Lupane- and Friedelane-Type Triterpenoids from Celastrus stylosus. Chemistry & biodiversity. 2015 Aug; 12(8):1222-8. doi: 10.1002/cbdv.201400269. [PMID: 26265574]
  • Mei-Hua Yu, Zheng-Feng Shi, Bang-Wei Yu, En-Hao Pi, He-Yao Wang, Ai-Jun Hou, Chun Lei. Triterpenoids and α-glucosidase inhibitory constituents from Salacia hainanensis. Fitoterapia. 2014 Oct; 98(?):143-8. doi: 10.1016/j.fitote.2014.07.016. [PMID: 25073097]
  • Wirongrong Kaweetripob, Chulabhorn Mahidol, Hunsa Prawat, Somsak Ruchirawat. Lupane, friedelane, oleanane, and ursane triterpenes from the stem of Siphonodon celastrineus Griff. Phytochemistry. 2013 Dec; 96(?):404-17. doi: 10.1016/j.phytochem.2013.09.027. [PMID: 24156869]
  • Wei-Guang Shan, Li-Wen Zhang, Jia-Gui Xiang, Zha-Jun Zhan. Natural friedelanes. Chemistry & biodiversity. 2013 Aug; 10(8):1392-434. doi: 10.1002/cbdv.201100256. [PMID: 23939791]
  • Alejandro E Ardiles, Agueda González-Rodríguez, Marvin J Núñez, Nayra R Perestelo, Virginia Pardo, Ignacio A Jiménez, Angela M Valverde, Isabel L Bazzocchi. Studies of naturally occurring friedelane triterpenoids as insulin sensitizers in the treatment type 2 diabetes mellitus. Phytochemistry. 2012 Dec; 84(?):116-24. doi: 10.1016/j.phytochem.2012.07.025. [PMID: 22925829]
  • James D Simo Mpetga, Yu Shen, Pierre Tane, Shi-Fei Li, Hong-Ping He, Hippolyte K Wabo, Mathieu Tene, Ying Leng, Xiao-Jiang Hao. Cycloartane and friedelane triterpenoids from the leaves of Caloncoba glauca and their evaluation for inhibition of 11β-hydroxysteroid dehydrogenases. Journal of natural products. 2012 Apr; 75(4):599-604. doi: 10.1021/np200831c. [PMID: 22360639]
  • Pathom Somwong, Rutt Suttisri, Anumart Buakeaw. A new 1,3-diketofriedelane triterpene from Salacia verrucosa. Fitoterapia. 2011 Oct; 82(7):1047-51. doi: 10.1016/j.fitote.2011.06.007. [PMID: 21745551]
  • Anupam Bishayee, Shamima Ahmed, Nikoleta Brankov, Marjorie Perloff. Triterpenoids as potential agents for the chemoprevention and therapy of breast cancer. Frontiers in bioscience (Landmark edition). 2011 01; 16(3):980-96. doi: 10.2741/3730. [PMID: 21196213]
  • Blanca M Reyes, María Teresa Ramírez-Apan, Rubén A Toscano, Guillermo Delgado. Triterpenes from Garcia parviflora. Cytotoxic evaluation of natural and semisynthetic friedelanes. Journal of natural products. 2010 Nov; 73(11):1839-45. doi: 10.1021/np100440p. [PMID: 20958014]
  • David Torres-Romero, Beatriz King-Díaz, Reto J Strasser, Ignacio A Jiménez, Blas Lotina-Hennsen, Isabel L Bazzocchi. Friedelane triterpenes from Celastrus vulcanicola as photosynthetic inhibitors. Journal of agricultural and food chemistry. 2010 Oct; 58(20):10847-54. doi: 10.1021/jf1022115. [PMID: 20873773]
  • Qi-kang Ya, Wen-jie Lu, Jia-yuan Chen, Xiao Tan. [Studies on the chemical constituents from the antithrombus activity extract of Radix Aerio Fici Microcarpae]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2010 Aug; 33(8):1254-6. doi: ". [PMID: 21213536]
  • Anabel Ortíz, Alexandre Cardoso-Taketa, Mario Rodríguez Monroy, Jesús Arellano, Georgina Hernández, María Luisa Villarreal. Transformed cell suspension culture of Galphimia glauca producing sedative nor-friedelanes. Planta medica. 2010 Mar; 76(4):386-92. doi: 10.1055/s-0029-1186166. [PMID: 19809970]
  • David Dako Chiozem, Hanh Trinh-Van-Dufat, Jean Duplex Wansi, Céline Mbazoa Djama, Véronique Simone Fannang, Elisabeth Seguin, François Tillequin, Jean Wandji. New friedelane triterpenoids with antimicrobial activity from the stems of Drypetes paxii. Chemical & pharmaceutical bulletin. 2009 Oct; 57(10):1119-22. doi: 10.1248/cpb.57.1119. [PMID: 19801870]
  • Cristina Moiteiro, Maria João Marcelo Curto, Nagla Mohamed, María Bailén, Rafael Martínez-Díaz, Azucena González-Coloma. Biovalorization of friedelane triterpenes derived from cork processing industry byproducts. Journal of agricultural and food chemistry. 2006 May; 54(10):3566-71. doi: 10.1021/jf0531151. [PMID: 19127726]
  • Blanca L Náder, Alexandre T Cardoso Taketa, Gabriel Iturriaga, Rogelio Pereda-Miranda, Ma Luisa Villarreal. Genetic transformation of Glaphimia glauca by Agrobacterium rhizogenes and the production of norfriedelanes. Planta medica. 2004 Dec; 70(12):1174-9. doi: 10.1055/s-2004-835848. [PMID: 15643554]
  • Hyo-Jin An, Hyun-Ja Jeong, Eun-Hee Lee, Yun-Kyung Kim, Woo-Jun Hwang, Su-Jin Yoo, Seung-Heon Hong, Hyung-Min Kim. Xanthii fructus inhibits inflammatory responses in LPS-stimulated mouse peritoneal macrophages. Inflammation. 2004 Oct; 28(5):263-70. doi: 10.1007/s10753-004-6049-9. [PMID: 16133999]
  • C Moiteiro, F Justino, R Tavares, M J Marcelo-Curto, M H Florêncio, M S Nascimento, M Pedro, F Cerqueira, M M Pinto. Synthetic secofriedelane and friedelane derivatives as inhibitors of human lymphocyte proliferation and growth of human cancer cell lines in vitro. Journal of natural products. 2001 Oct; 64(10):1273-7. doi: 10.1021/np010217m. [PMID: 11678649]