2,6-Diamino-4-oxo-5-formamidopyrimidine (BioDeep_00000845665)

   


代谢物信息卡片


2,6-Diamino-4-oxo-5-formamidopyrimidine

化学式: C5H7N5O2 (169.05997220000003)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C(=O)NC1C(=NC(=NC1=O)N)N
InChI: InChI=1S/C5H7N5O2/c6-3-2(8-1-11)4(12)10-5(7)9-3/h1-2H,(H,8,11)(H4,6,7,9,10,12)

描述信息

同义名列表

1 个代谢物同义名

2,6-Diamino-4-oxo-5-formamidopyrimidine



数据库引用编号

3 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(1)

BioCyc(0)

PlantCyc(0)

代谢反应

80 个相关的代谢反应过程信息。

Reactome(80)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Priyanka Sharma, Carmen P Wong, Emily Ho, Harini Sampath. Catalytic activity of OGG1 is impaired by Zinc deficiency. DNA repair. 2024 Feb; 134(?):103628. doi: 10.1016/j.dnarep.2024.103628. [PMID: 38228016]
  • Martine Extermann, Christiaan Leeuwenburgh, Laila Samiian, Marina Sehovic, Jinze Xu, Christopher Cubitt, Paul B Jacobsen, Marco Pahor, Stephen R Grobmyer, Todd M Manini. Impact of chemotherapy on medium-term physical function and activity of older breast cancer survivors, and associated biomarkers. Journal of geriatric oncology. 2017 01; 8(1):69-75. doi: 10.1016/j.jgo.2016.09.004. [PMID: 27743848]
  • Michael K Chan, Maria T Ocampo-Hafalla, Vladimir Vartanian, Pawel Jaruga, Güldal Kirkali, Karen L Koenig, Stuart Brown, R Stephen Lloyd, Miral Dizdaroglu, George W Teebor. Targeted deletion of the genes encoding NTH1 and NEIL1 DNA N-glycosylases reveals the existence of novel carcinogenic oxidative damage to DNA. DNA repair. 2009 Jul; 8(7):786-94. doi: 10.1016/j.dnarep.2009.03.001. [PMID: 19346169]
  • Bhaskar Malayappan, Timothy J Garrett, Mark Segal, Christiaan Leeuwenburgh. Urinary analysis of 8-oxoguanine, 8-oxoguanosine, fapy-guanine and 8-oxo-2'-deoxyguanosine by high-performance liquid chromatography-electrospray tandem mass spectrometry as a measure of oxidative stress. Journal of chromatography. A. 2007 Oct; 1167(1):54-62. doi: 10.1016/j.chroma.2007.08.024. [PMID: 17765254]
  • Teresa Morales-Ruiz, Mustafa Birincioglu, Pawel Jaruga, Henry Rodriguez, Teresa Roldan-Arjona, Miral Dizdaroglu. Arabidopsis thaliana Ogg1 protein excises 8-hydroxyguanine and 2,6-diamino-4-hydroxy-5-formamidopyrimidine from oxidatively damaged DNA containing multiple lesions. Biochemistry. 2003 Mar; 42(10):3089-95. doi: 10.1021/bi027226u. [PMID: 12627976]
  • G D Castro, M I Díaz Gómez, J A Castro. DNA bases attack by reactive metabolites produced during carbon tetrachloride biotransformation and promotion of liver microsomal lipid peroxidation. Research communications in molecular pathology and pharmacology. 1997 Mar; 95(3):253-8. doi: . [PMID: 9144833]