Pseudoisocyanine (BioDeep_00000845526)
代谢物信息卡片
化学式: C23H23N2+ (327.1861138)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCN1C(=CC2=[N+](C3=CC=CC=C3C=C2)CC)C=CC4=CC=CC=C41
InChI: InChI=1S/C23H23N2/c1-3-24-20(15-13-18-9-5-7-11-22(18)24)17-21-16-14-19-10-6-8-12-23(19)25(21)4-2/h5-17H,3-4H2,1-2H3/q+1
数据库引用编号
6 个数据库交叉引用编号
- ChEBI: CHEBI:38002
- ChEBI: CHEBI:37994
- PubChem: 5484463
- ChEMBL: CHEMBL1197556
- CAS: 64496-43-1
- CAS: 20766-49-8
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- John Sebastiani, M Danielle McDonald. The role of uptake and degradation in the regulation of peripheral serotonin dynamics in Gulf toadfish, Opsanus beta.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology.
2021 08; 258(?):110980. doi:
10.1016/j.cbpa.2021.110980
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European journal of pharmacology.
2020 Sep; 883(?):173285. doi:
10.1016/j.ejphar.2020.173285
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Physiological reports.
2019 11; 7(22):e14297. doi:
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The Journal of physiology.
2015 Apr; 593(7):1715-29. doi:
10.1113/jphysiol.2014.285312
. [PMID: 25694117] - Patrick S Hosford, Steve W Mifflin, Andrew G Ramage. 5-hydroxytryptamine-mediated neurotransmission modulates spontaneous and vagal-evoked glutamate release in the nucleus of the solitary tract effect of uptake blockade.
The Journal of pharmacology and experimental therapeutics.
2014 May; 349(2):288-96. doi:
10.1124/jpet.113.211334
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The Journal of neuroscience : the official journal of the Society for Neuroscience.
2013 Jun; 33(25):10534-43. doi:
10.1523/jneurosci.5687-11.2013
. [PMID: 23785165] - Catherine E Hagan, James O Schenk, John F Neumaier. The contribution of low-affinity transport mechanisms to serotonin clearance in synaptosomes.
Synapse (New York, N.Y.).
2011 Oct; 65(10):1015-23. doi:
10.1002/syn.20929
. [PMID: 21437992] - Jonathan E Hill, Khadijah Makky, Lalita Shrestha, Cecilia J Hillard, Paul J Gasser. Natural and synthetic corticosteroids inhibit uptake 2-mediated transport in CNS neurons.
Physiology & behavior.
2011 Aug; 104(2):306-11. doi:
10.1016/j.physbeh.2010.11.012
. [PMID: 21081135] - Haichuan Duan, Joanne Wang. Selective transport of monoamine neurotransmitters by human plasma membrane monoamine transporter and organic cation transporter 3.
The Journal of pharmacology and experimental therapeutics.
2010 Dec; 335(3):743-53. doi:
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Langmuir : the ACS journal of surfaces and colloids.
2009 Sep; 25(18):10719-29. doi:
10.1021/la901227h
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American journal of physiology. Regulatory, integrative and comparative physiology.
2008 Jun; 294(6):R1988-95. doi:
10.1152/ajpregu.00016.2008
. [PMID: 18417653] - M Yu Iniouchine, D A Sibarov, A B Volnova, C A Jimenez-Rivera, A D Nozdrachev. Blockers of monoamine transporters influence high dopamine concentration uptake in rat brain slices.
Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections.
2008 Mar; 419(?):80-2. doi:
10.1134/s0012496608020038
. [PMID: 18536267] - R Monteiro, C Calhau, F Martel, A Faria, N Mateus, I Azevedo. Modulation of MPP+ uptake by tea and some of its components in Caco-2 cells.
Naunyn-Schmiedeberg's archives of pharmacology.
2005 Aug; 372(2):147-52. doi:
10.1007/s00210-005-0012-7
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British journal of pharmacology.
2002 Jul; 136(6):829-36. doi:
10.1038/sj.bjp.0704785
. [PMID: 12110607] - A J Dudley, K Bleasby, C D Brown. The organic cation transporter OCT2 mediates the uptake of beta-adrenoceptor antagonists across the apical membrane of renal LLC-PK(1) cell monolayers.
British journal of pharmacology.
2000 Sep; 131(1):71-9. doi:
10.1038/sj.bjp.0703518
. [PMID: 10960071] - M Hayer, H Bönisch, M Brüss. Molecular cloning, functional characterization and genomic organization of four alternatively spliced isoforms of the human organic cation transporter 1 (hOCT1/SLC22A1).
Annals of human genetics.
1999 Nov; 63(Pt 6):473-82. doi:
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. [PMID: 11388889] - M Okuda, Y Urakami, H Saito, K Inui. Molecular mechanisms of organic cation transport in OCT2-expressing Xenopus oocytes.
Biochimica et biophysica acta.
1999 Mar; 1417(2):224-31. doi:
10.1016/s0005-2736(99)00005-x
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The Journal of biological chemistry.
1998 Nov; 273(47):30915-20. doi:
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. [PMID: 9812985] - L Zhang, M E Schaner, K M Giacomini. Functional characterization of an organic cation transporter (hOCT1) in a transiently transfected human cell line (HeLa).
The Journal of pharmacology and experimental therapeutics.
1998 Jul; 286(1):354-61. doi:
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DNA and cell biology.
1997 Jul; 16(7):871-81. doi:
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Molecular pharmacology.
1997 Jun; 51(6):913-21. doi:
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1996 Aug; 354(3):320-6. doi:
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. [PMID: 8878062] - H Russ, B Friedgen, B Königs, C Schumacher, K H Graefe, E Schömig. Pharmacokinetic and alpha 1-adrenoceptor antagonistic properties of two cyanine-type inhibitors of extraneuronal monoamine transport.
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. [PMID: 8878056] - D Gründemann, V Gorboulev, S Gambaryan, M Veyhl, H Koepsell. Drug excretion mediated by a new prototype of polyspecific transporter.
Nature.
1994 Dec; 372(6506):549-52. doi:
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. [PMID: 7990927] - H Russ, W Engel, E Schömig. Isocyanines and pseudoisocyanines as a novel class of potent noradrenaline transport inhibitors: synthesis, detection, and biological activity.
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