G(M1)-Oligosaccharide (BioDeep_00000845379)
代谢物信息卡片
化学式: C37H62N2O29 (998.3438082)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(=O)NC1C(CC(OC1C(C(CO)O)O)(C(=O)O)OC2C(C(OC(C2OC3C(C(C(C(O3)CO)O)OC4C(C(C(C(O4)CO)O)O)O)NC(=O)C)CO)OC5C(OC(C(C5O)O)O)CO)O)O
InChI: InChI=1S/C37H62N2O29/c1-9(45)38-17-11(47)3-37(36(58)59,67-30(17)19(49)12(48)4-40)68-31-26(56)35(64-27-15(7-43)60-32(57)24(54)23(27)53)63-16(8-44)28(31)65-33-18(39-10(2)46)29(21(51)14(6-42)61-33)66-34-25(55)22(52)20(50)13(5-41)62-34/h11-35,40-44,47-57H,3-8H2,1-2H3,(H,38,45)(H,39,46)(H,58,59)/t11-,12+,13+,14+,15+,16+,17+,18+,19+,20-,21-,22-,23+,24+,25+,26+,27+,28-,29+,30+,31+,32+,33-,34-,35-,37-/m0/s1
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Elena Chiricozzi, Margherita Maggioni, Erika di Biase, Giulia Lunghi, Maria Fazzari, Nicoletta Loberto, Maffioli Elisa, Francesca Grassi Scalvini, Gabriella Tedeschi, Sandro Sonnino. The Neuroprotective Role of the GM1 Oligosaccharide, II3Neu5Ac-Gg4, in Neuroblastoma Cells.
Molecular neurobiology.
2019 Oct; 56(10):6673-6702. doi:
10.1007/s12035-019-1556-8. [PMID: 30911934] - Haydn R Sinclair, Fred Kemp, Jaap de Slegte, Glenn R Gibson, Robert A Rastall. Carbohydrate-based anti-adhesive inhibition of Vibrio cholerae toxin binding to GM1-OS immobilized into artificial planar lipid membranes.
Carbohydrate research.
2009 Oct; 344(15):1968-74. doi:
10.1016/j.carres.2009.06.038. [PMID: 19665695] - Yong Chen, Jie Qin, Jiye Cai, Zheng W Chen. Cold induces micro- and nano-scale reorganization of lipid raft markers at mounds of T-cell membrane fluctuations.
PloS one.
2009; 4(4):e5386. doi:
10.1371/journal.pone.0005386. [PMID: 19404395] - Christian Meyer zum Büschenfelde, Yvonne Feuerstacke, Katharina S Götze, Katrin Scholze, Christian Peschel. GM1 expression of non-Hodgkin's lymphoma determines susceptibility to rituximab treatment.
Cancer research.
2008 Jul; 68(13):5414-22. doi:
10.1158/0008-5472.can-07-5601. [PMID: 18593944] - Masaaki Noguchi, Kiyoshi Mori, Shigetaka Yamazaki, Kouichi Suda, Naotake Sato, Kazuo Oshimi. Multifocal motor neuropathy caused by a B-cell lymphoma producing a monoclonal IgM autoantibody against peripheral nerve myelin glycolipids GM1 and GD1b.
British journal of haematology.
2003 Nov; 123(4):600-5. doi:
10.1046/j.1365-2141.2003.04651.x. [PMID: 14616962] - Tyrone Bowes, Eric R Wagner, Judith Boffey, Dawn Nicholl, Lynne Cochrane, Mustapha Benboubetra, Joe Conner, Keiko Furukawa, Koichi Furukawa, Hugh J Willison. Tolerance to self gangliosides is the major factor restricting the antibody response to lipopolysaccharide core oligosaccharides in Campylobacter jejuni strains associated with Guillain-Barré syndrome.
Infection and immunity.
2002 Sep; 70(9):5008-18. doi:
10.1128/iai.70.9.5008-5018.2002. [PMID: 12183547] - A Neisser, H Bernheimer, T Berger, A P Moran, B Schwerer. Serum antibodies against gangliosides and Campylobacter jejuni lipopolysaccharides in Miller Fisher syndrome.
Infection and immunity.
1997 Oct; 65(10):4038-42. doi:
10.1128/iai.65.10.4038-4042.1997. [PMID: 9317004] - B C Jacobs, H P Endtz, F G van der Meché, M P Hazenberg, M A de Klerk, P A van Doorn. Humoral immune response against Campylobacter jejuni lipopolysaccharides in Guillain-Barré and Miller Fisher syndrome.
Journal of neuroimmunology.
1997 Oct; 79(1):62-8. doi:
10.1016/s0165-5728(97)00110-0. [PMID: 9357448] - P G Oomes, B C Jacobs, M P Hazenberg, J R Bänffer, F G van der Meché. Anti-GM1 IgG antibodies and Campylobacter bacteria in Guillain-Barré syndrome: evidence of molecular mimicry.
Annals of neurology.
1995 Aug; 38(2):170-5. doi:
10.1002/ana.410380208. [PMID: 7654064]