Bisabolane (BioDeep_00000845016)
代谢物信息卡片
Bisabolane
化学式: C15H30 (210.234738)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1CCC(CC1)C(C)CCCC(C)C
InChI: InChI=1S/C15H30/c1-12(2)6-5-7-14(4)15-10-8-13(3)9-11-15/h12-15H,5-11H2,1-4H3
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Homa Karami, Mohammad Reza Niavand, Rasool Haddadi, Alireza Noriyan, Seyed Yaser Vafaei. Development of a hydrogel containing bisabolol-loaded nanocapsules for the treatment of atopic dermatitis in a Balb/c mice model.
International journal of pharmaceutics.
2024 May; 656(?):124029. doi:
10.1016/j.ijpharm.2024.124029. [PMID: 38527566] - Dhouha Alimi, Manel Hraoui, Azhar Hajri, Wael Taamalli, Slimen Selmi, Hichem Sebai. Bioactivity and molecular docking studies of selected plant compounds.
Journal of the science of food and agriculture.
2024 May; 104(7):4391-4399. doi:
10.1002/jsfa.13327. [PMID: 38323805] - Marwa Mohamed Soliman, Yasmin Mohamed Elsaba, M S A Soliman, Eman Zakaria Ahmed. Composition and antimicrobial activity of Rosmarinus officinalis L. and Artemisia monosperma L. leaf essential oils and methanolic extracts from plants grown in normal and saline habitats in Egypt.
Scientific reports.
2024 03; 14(1):7342. doi:
10.1038/s41598-024-57301-w. [PMID: 38538682] - Josyelem Tiburtino Leite Chaves, Geovane da Silva Dias, Marina Mariá Pereira, Ludmila da Silva Bastos, Maria Isabel Almeida Souza, Larissa Fonseca Andrade Vieira, Ana Cardoso Clemente Filha Ferreira de Paula, Cláudia Araújo Marco, Paulo Eduardo Ribeiro Marchiori, Elisa Monteze Bicalho. New Perspective on the Use of α-Bisabolol for Weed Control.
Journal of agricultural and food chemistry.
2024 Mar; 72(12):6289-6301. doi:
10.1021/acs.jafc.3c08566. [PMID: 38502021] - Carlos Jonnathan Castro-Juárez, Silvia Luna-Suárez, Flor de Fátima Rosas-Cárdenas, Nemesio Villa-Ruano. Hernandulcin Production in Elicited Hairy Roots of Phyla scaberrima: Toward Sustainable Production of a Non-Caloric Sweetener with Nutraceutical Properties.
Chemistry & biodiversity.
2024 Mar; 21(3):e202302095. doi:
10.1002/cbdv.202302095. [PMID: 38334300] - Qianqian Cheng, Bin Lyu, Jingweng Hu, Zhiqiang Zhang, Yusheng Huang, Zhenhua Wang. Research on the antipruritic active ingredients of Mikania micrantha.
Fitoterapia.
2024 Jan; 174(?):105837. doi:
10.1016/j.fitote.2024.105837. [PMID: 38286314] - John Staton Laws, Scott D Smid. Characterizing cannabis-prevalent terpenes for neuroprotection reveal a role for α and β-pinenes in mitigating amyloid β-evoked neurotoxicity and aggregation in vitro.
Neurotoxicology.
2024 Jan; 100(?):16-24. doi:
10.1016/j.neuro.2023.12.004. [PMID: 38070653] - Sandra Regina Nunes de Andrade Medeiros, Iverson Conrado Bezerra, Artur José da Silva, Lucas Aleixo Leal Pedroza, Regildo Max Gomes Martins, Ana Maria Henrique Moniz, Ana Cristina Gonçalves Reis de Melo, Weslley Souza Paiva, Priscila Gubert, Antonio Alves de Melo Filho. In Vitro and In Silico Antioxidant Activity and Molecular Characterization of Bauhinia ungulata L. Essential Oil.
Chemistry & biodiversity.
2023 Dec; ?(?):e202301536. doi:
10.1002/cbdv.202301536. [PMID: 38090811] - Mahalingam Jeyakumar, Devasahayam Jaya Balan, Chandramohan Kiruthiga, Sakthivel Jafni, Kasi Pandima Devi. α-bisabolol β-d-fucopyranoside (ABFP) ameliorates scopolamine-induced memory deficits through cholinesterase inhibition and attenuation of oxidative stress in zebrafish (Danio rerio).
Journal of biochemical and molecular toxicology.
2023 Nov; ?(?):e23580. doi:
10.1002/jbt.23580. [PMID: 37961937] - Tuan Quoc Doan, Dien Dinh, Thang Nam Tran, Phu Quynh Dinh Nguyen, Chau Bao Hoai Nguyen, Nhan Trong Le, Hung Quoc Vo, Duc Viet Ho, Anh Le Tuan, Hoai Thi Nguyen, Isiaka A Ogunwande. Chemical composition and acetylcholinesterase inhibitory activity of essential oil from the leaves of Mitrephora poilanei Weeras. & R.M.K. Saunders.
Natural product research.
2023 Jun; ?(?):1-5. doi:
10.1080/14786419.2023.2227989. [PMID: 37357615] - Ying-Ying Zhao, Yu-Jie Li, Xiao-Mei Yu, Qin-Ting Su, Li-Wen Wang, Yu-Shu Zhu, Yan-Hui Fu, Guang-Ying Chen, Yan-Ping Liu. Bisabolane-type sesquiterpenoids with potential anti-inflammatory and anti-HIV activities from the stems and leaves of Morinda citrifolia.
Natural product research.
2023 Jun; 37(12):1961-1968. doi:
10.1080/14786419.2022.2112577. [PMID: 35975763] - Yu-Qin Guo, Guang-Xu Wu, Cheng Peng, Yun-Qiu Fan, Lei Li, Fei Liu, Liang Xiong. New Bisabolane-Type Sesquiterpenoids from Curcuma longa and Their Anti-Atherosclerotic Activity.
Molecules (Basel, Switzerland).
2023 Mar; 28(6):. doi:
10.3390/molecules28062704. [PMID: 36985676] - Armelle Tafouo Tsakou, Blanche Laure Ndontsa, Eric Carly Nono Nono, Nadine Tseme Wandji, Gabin Thierry Mbahbou Bitchagno, Jean Jules Kezetas Bankeu, Leon Azefack Tapondjou, Norbert Sewald, Bruno Ndjakou Lenta. Elemane-Type Sesquiterpene, Acetonide Derived Polyacetylene and Other Constituents from the Whole Plant of Gymnanthemum theophrastifolium (Schweinf. ex Oliv. & Hiern) H.Rob. and Their Chemophenetic Significance.
Chemistry & biodiversity.
2023 Mar; 20(3):e202200196. doi:
10.1002/cbdv.202200196. [PMID: 36879423] - Vincenzo Ilardi, Giulia D'Agostino, Maurizio Bruno. The chemical composition of the aerial parts essential oil of Achillea cretica L. (Asteraceae) growing wild in Crete (Greece).
Natural product research.
2022 Nov; ?(?):1-6. doi:
10.1080/14786419.2022.2148247. [PMID: 36408972] - Qi Guo, Ya-Wen Li, Fang Yan, Ke Li, Yue-Tong Wang, Chao Ye, Tian-Qiong Shi, He Huang. Dual cytoplasmic-peroxisomal engineering for high-yield production of sesquiterpene α-humulene in Yarrowia lipolytica.
Biotechnology and bioengineering.
2022 10; 119(10):2819-2830. doi:
10.1002/bit.28176. [PMID: 35798689] - Vidya Devanathadesikan Seshadri, Atif Abdulwahab A Oyouni, Waleed M Bawazir, Suliman A Alsagaby, Khalaf F Alsharif, Ashraf Albrakati, Osama M Al-Amer. Zingiberene exerts chemopreventive activity against 7,12-dimethylbenz(a)anthracene-induced breast cancer in Sprague-Dawley rats.
Journal of biochemical and molecular toxicology.
2022 Oct; 36(10):e23146. doi:
10.1002/jbt.23146. [PMID: 35698847] - Seenipandi Arunachalam, M F Nagoor Meeran, Sheikh Azimullah, Niraj Kumar Jha, Dhanya Saraswathiamma, Sandeep Subramanya, Alia Albawardi, Shreesh Ojha. α-Bisabolol Attenuates Doxorubicin Induced Renal Toxicity by Modulating NF-κB/MAPK Signaling and Caspase-Dependent Apoptosis in Rats.
International journal of molecular sciences.
2022 Sep; 23(18):. doi:
10.3390/ijms231810528. [PMID: 36142441] - Heba A S El-Nashar, Mai Adel, Mohamed El-Shazly, Ibrahim S Yahia, Hamdy S El Sheshtawy, Adel A Almalki, Nehal Ibrahim. Chemical Composition, Antiaging Activities and Molecular Docking Studies of Essential Oils from Acca sellowiana (Feijoa).
Chemistry & biodiversity.
2022 Sep; 19(9):e202200272. doi:
10.1002/cbdv.202200272. [PMID: 35938449] - Nurul Huda Alwakil, Mohamad Suffian Mohamad Annuar, Mahanom Jalil. Synergistic Effects of Plant Growth Regulators and Elicitors on α-Humulene and Zerumbone Production in Zingiber zerumbet Smith Adventitious Root Cultures.
Molecules (Basel, Switzerland).
2022 Jul; 27(15):. doi:
10.3390/molecules27154744. [PMID: 35897918] - Guangxia Li, Huayan Wu, Liqin Sun, Kang Cheng, Zhi Lv, Kaixian Chen, Fei Qian, Yiming Li. (-)-α-Bisabolol Alleviates Atopic Dermatitis by Inhibiting MAPK and NF-κB Signaling in Mast Cell.
Molecules (Basel, Switzerland).
2022 Jun; 27(13):. doi:
10.3390/molecules27133985. [PMID: 35807237] - Cui-Fang Wang, Xue-Qiong Yang, Jing Sun, Ting Wang, Han-Rong Cui, Ya-Bin Yang, Zhong-Tao Ding. New Metabolites, Antifeedant, Insecticidal Activities, and Reciprocal Relationship Between Insect and Fungus from Endophyte Schizophyllum commune.
Chemistry & biodiversity.
2022 Jun; 19(6):e202200130. doi:
10.1002/cbdv.202200130. [PMID: 35580000] - John Staton Laws Iii, Srijan Shrestha, Scott D Smid. Cannabis terpenes display variable protective and anti-aggregatory actions against neurotoxic β amyloid in vitro: highlighting the protective bioactivity of α-bisabolol in motorneuronal-like NSC-34 cells.
Neurotoxicology.
2022 05; 90(?):81-87. doi:
10.1016/j.neuro.2022.03.001. [PMID: 35278524] - Lujain Bader Eddin, Niraj Kumar Jha, Sameer N Goyal, Yogeeta O Agrawal, Sandeep B Subramanya, Salim M A Bastaki, Shreesh Ojha. Health Benefits, Pharmacological Effects, Molecular Mechanisms, and Therapeutic Potential of α-Bisabolol.
Nutrients.
2022 Mar; 14(7):. doi:
10.3390/nu14071370. [PMID: 35405982] - Emanuel Paula Magalhães, Brenna Pinheiro Silva, Natália Luna Aires, Lyanna Rodrigues Ribeiro, Arif Ali, Mariana Maciel Cavalcanti, João Victor Serra Nunes, Tiago Lima Sampaio, Ramon Róseo Paula Pessoa Bezerra de Menezes, Alice Maria Costa Martins. (-)-α-Bisabolol as a protective agent against epithelial renal cytotoxicity induced by amphotericin B.
Life sciences.
2022 Feb; 291(?):120271. doi:
10.1016/j.lfs.2021.120271. [PMID: 34974077] - Mary A Egbuta, Shane McIntosh, Daniel L E Waters, Tony Vancov, Lei Liu. In Vitro Anti-Inflammatory Activity of Essential Oil and β-Bisabolol Derived from Cotton Gin Trash.
Molecules (Basel, Switzerland).
2022 Jan; 27(2):. doi:
10.3390/molecules27020526. [PMID: 35056836] - Paula Marchesini, Ari Sérgio de Oliveira Lemos, Ricardo de Oliveira Barbosa Bitencourt, Jéssica Fiorotti, Isabele da Costa Angelo, Rodrigo Luiz Fabri, Lívio Martins Costa-Júnior, Welber Daniel Zaneti Lopes, Vânia Rita Elias Pinheiro Bittencourt, Caio Monteiro. Assessment of lipid profile in fat body and eggs of Rhipicephalus microplus engorged females exposed to (E)-cinnamaldehyde and α-bisabolol, potential acaricide compounds.
Veterinary parasitology.
2021 Dec; 300(?):109596. doi:
10.1016/j.vetpar.2021.109596. [PMID: 34695723] - Hong-Zhen Shu, Cheng Peng, Lan Bu, Li Guo, Fei Liu, Liang Xiong. Bisabolane-type sesquiterpenoids: Structural diversity and biological activity.
Phytochemistry.
2021 Dec; 192(?):112927. doi:
10.1016/j.phytochem.2021.112927. [PMID: 34492546] - Silvia Di Giacomo, Alessia Mariano, Marco Gullì, Caterina Fraschetti, Annabella Vitalone, Antonello Filippi, Luisa Mannina, Anna Scotto d'Abusco, Antonella Di Sotto. Role of Caryophyllane Sesquiterpenes in the Entourage Effect of Felina 32 Hemp Inflorescence Phytocomplex in Triple Negative MDA-MB-468 Breast Cancer Cells.
Molecules (Basel, Switzerland).
2021 Nov; 26(21):. doi:
10.3390/molecules26216688. [PMID: 34771097] - Xue-Long Yan, Jun-Sang, Xu Zhang, Yan Lin, Qing-De Long, Qin-Feng Zhu, Shang-Gao Liao. Euphorboside A, a cytotoxic meroterpenoid glycoside with an unusual humulene-phloroglucinol skeleton from Euphorbia kansuensis.
Fitoterapia.
2021 Sep; 153(?):104966. doi:
10.1016/j.fitote.2021.104966. [PMID: 34144143] - Huihui Ti, Zhitong Mai, Zhoulang Wang, Wenjie Zhang, Mengjie Xiao, Zifeng Yang, Pangchui Shaw. Bisabolane-type sesquiterpenoids from Curcuma longa L. exert anti-influenza and anti-inflammatory activities through NF-κB/MAPK and RIG-1/STAT1/2 signaling pathways.
Food & function.
2021 Aug; 12(15):6697-6711. doi:
10.1039/d1fo01212f. [PMID: 34179914] - Karolina Połeć, Karolina Olechowska, Amanda Klejdysz, Michał Dymek, Rafał Rachwalik, Elżbieta Sikora, Katarzyna Hąc-Wydro. The influence of ergosterol on the action of the hop oil and its major terpenes on model fungi membranes. Towards understanding the mechanism of action of phytocompounds for food and plant protection.
Chemistry and physics of lipids.
2021 08; 238(?):105092. doi:
10.1016/j.chemphyslip.2021.105092. [PMID: 34000279] - Jie Wang, Li Liu, Li-Li Hong, Kai-Xuan Zhan, Zheng-Jiang Lin, Wei-Hua Jiao, Hou-Wen Lin. New bisabolane-type phenolic sesquiterpenoids from the marine sponge Plakortis simplex.
Chinese journal of natural medicines.
2021 Aug; 19(8):626-631. doi:
10.1016/s1875-5364(21)60062-6. [PMID: 34419262] - Eduardo Valarezo, Génesis Gaona-Granda, Vladimir Morocho, Luis Cartuche, James Calva, Miguel Angel Meneses. Chemical Constituents of the Essential Oil from Ecuadorian Endemic Species Croton ferrugineus and Its Antimicrobial, Antioxidant and α-Glucosidase Inhibitory Activity.
Molecules (Basel, Switzerland).
2021 Jul; 26(15):. doi:
10.3390/molecules26154608. [PMID: 34361759] - Sofia Milker, Anne Sydow, Ingrid Torres-Monroy, Guido Jach, Frederik Faust, Lea Kranz, Ljubov Tkatschuk, Dirk Holtmann. Gram-scale production of the sesquiterpene α-humulene with Cupriavidus necator.
Biotechnology and bioengineering.
2021 07; 118(7):2694-2702. doi:
10.1002/bit.27788. [PMID: 33844284] - Jianwei Li, Radhiga Thangaiyan, Kanimozhi Govindasamy, Jianxia Wei. Anti-inflammatory and anti-apoptotic effect of zingiberene on isoproterenol-induced myocardial infarction in experimental animals.
Human & experimental toxicology.
2021 Jun; 40(6):915-927. doi:
10.1177/0960327120975131. [PMID: 33242989] - Ziqiang Bai, Chuansheng Yao, Junlong Zhu, Yuanyuan Xie, Xiang-Yang Ye, Renren Bai, Tian Xie. Anti-Tumor Drug Discovery Based on Natural Product β-Elemene: Anti-Tumor Mechanisms and Structural Modification.
Molecules (Basel, Switzerland).
2021 Mar; 26(6):. doi:
10.3390/molecules26061499. [PMID: 33801899] - Sebastian Zabel, Wolfgang Brandt, Andrea Porzel, Benedikt Athmer, Stefan Bennewitz, Petra Schäfer, Ruy Kortbeek, Petra Bleeker, Alain Tissier. A single cytochrome P450 oxidase from Solanum habrochaites sequentially oxidizes 7-epi-zingiberene to derivatives toxic to whiteflies and various microorganisms.
The Plant journal : for cell and molecular biology.
2021 03; 105(5):1309-1325. doi:
10.1111/tpj.15113. [PMID: 33617106] - Fumin Wang, Yong-Lak Park, Michael Gutensohn. Glandular Trichome-Derived Mono- and Sesquiterpenes of Tomato Have Contrasting Roles in the Interaction with the Potato Aphid Macrosiphum euphorbiae.
Journal of chemical ecology.
2021 Feb; 47(2):204-214. doi:
10.1007/s10886-021-01243-4. [PMID: 33447946] - Mohammad Firoznejhad, Abdollah Ghasemi Pirbalouti, Vahid Abdoosi, Atousa Aliahmadi. Chemical composition of essential oils from the underground parts of Glycyrrhiza echinata L. accessions growing wild in Northern Iran.
Natural product research.
2021 Jan; 35(1):162-166. doi:
10.1080/14786419.2019.1616721. [PMID: 31165644] - Shi Hu, Yan-Lei Ma, Jia-Ming Guo, Qing Wen, Gui Yan, Shuo Yang, Yan-Hui Fu, Yan-Ping Liu. Bisabolane sesquiterpenes from Clausena sanki with their potential anti-inflammatory activities.
Natural product research.
2020 Dec; 34(24):3499-3505. doi:
10.1080/14786419.2019.1582042. [PMID: 30931625] - Karoliny C R Almeida, Bruna B Silva, Cassia C F Alves, Tatiana M Vieira, Antônio E M Crotti, João M Souza, Carlos H G Martins, Arthur B Ribeiro, Iara S Squarisi, Denise C Tavares, Laura Dos S Bernabé, Lizandra G Magalhães, Mayker L D Miranda. Biological properties and chemical composition of essential oil from Nectandra megapotamica (Spreng.) Mez. leaves (Lauraceae).
Natural product research.
2020 Nov; 34(21):3149-3153. doi:
10.1080/14786419.2019.1608539. [PMID: 31084218] - Hayate Javed, M F Nagoor Meeran, Sheikh Azimullah, Lujain Bader Eddin, Vivek Dhar Dwivedi, Niraj Kumar Jha, Shreesh Ojha. α-Bisabolol, a Dietary Bioactive Phytochemical Attenuates Dopaminergic Neurodegeneration through Modulation of Oxidative Stress, Neuroinflammation and Apoptosis in Rotenone-Induced Rat Model of Parkinson's disease.
Biomolecules.
2020 10; 10(10):. doi:
10.3390/biom10101421. [PMID: 33049992] - Didjour Albert Kambiré, Acafou Thierry Yapi, Jean Brice Boti, Zana Adama Ouattara, Zanahi Félix Tonzibo, Jean-Jacques Filippi, Ange Bighelli, Félix Tomi. Two new eudesman-4α-ol epoxides from the stem essential oil of Laggera pterodonta from Côte d'Ivoire.
Natural product research.
2020 Oct; 34(19):2765-2771. doi:
10.1080/14786419.2019.1586701. [PMID: 30908078] - Li-Ping Feng, Li-He Lu, Ming-Rui Yuan, Shuang-Xi Mei, Xiao-Hui Li. Two pairs of bisabolane sesquiterpenoid stereoisomers, bisacurone D-G, from the rhizome of Curcuma longa L.
Fitoterapia.
2020 Oct; 146(?):104701. doi:
10.1016/j.fitote.2020.104701. [PMID: 32763365] - Anh Duc Nguyen, Donghyuk Kim, Eun Yeol Lee. Unlocking the biosynthesis of sesquiterpenoids from methane via the methylerythritol phosphate pathway in methanotrophic bacteria, using α-humulene as a model compound.
Metabolic engineering.
2020 09; 61(?):69-78. doi:
10.1016/j.ymben.2020.04.011. [PMID: 32387228] - Xin Wang, Yi Shen, Kiran Thakur, Jinzhi Han, Jian-Guo Zhang, Fei Hu, Zhao-Jun Wei. Antibacterial Activity and Mechanism of Ginger Essential Oil against Escherichia coli and Staphylococcus aureus.
Molecules (Basel, Switzerland).
2020 Aug; 25(17):. doi:
10.3390/molecules25173955. [PMID: 32872604] - T Soumya, P R Jayasree, M Deepak, P R Manish Kumar. Chemical composition, antioxidant and antiproliferative activities of essential oil from rhizome and leaves of Curcuma mutabilis Škorničk., M. Sabu & Prasanthk., endemic to Western Ghats of India.
Natural product research.
2020 Aug; 34(16):2336-2340. doi:
10.1080/14786419.2018.1533826. [PMID: 30724591] - Amanda Moreno-Rodríguez, Rosario Santos-Castro, Josefina Vázquez-Medrano, Rafael E Quintanar-Zúñiga, Fernando A García-García, Luis B Hernández-Portilla, Cesar M Flores-Ortiz. Effect of jasmonic acid on major terpenes and density of glandular trichomes in Lippia graveolens kunth (Verbenaceae).
Natural product research.
2020 Jul; 34(13):1942-1946. doi:
10.1080/14786419.2019.1566721. [PMID: 30724587] - Sonal Shah, Tushar Dhanani, Sonu Sharma, Raghuraj Singh, Satyanshu Kumar, Bhanu Kumar, Sharad Srivastava, Srikant Ghosh, Rajesh Kumar, Sanis Juliet. Development and Validation of a Reversed Phase High Performance Liquid Chromatography-Photodiode Array Detection Method for Simultaneous Identification and Quantification of Coumarin, Precocene-I, β-Caryophyllene Oxide, α-Humulene, and β-Caryophyllene in Ageratum Conyzoides Extracts and Essential Oils from Plants.
Journal of AOAC International.
2020 Jun; 103(3):857-864. doi:
10.1093/jaoacint/qsz038. [PMID: 33241362] - Sethuraman Sathya, Balakrishnan Shanmuganathan, Kasi Pandima Devi. Deciphering the anti-apoptotic potential of α-bisabolol loaded solid lipid nanoparticles against Aβ induced neurotoxicity in Neuro-2a cells.
Colloids and surfaces. B, Biointerfaces.
2020 Jun; 190(?):110948. doi:
10.1016/j.colsurfb.2020.110948. [PMID: 32160583] - Hye-In Jang, Ki-Jong Rhee, Yong-Bin Eom. Antibacterial and antibiofilm effects of α-humulene against Bacteroides fragilis.
Canadian journal of microbiology.
2020 Jun; 66(6):389-399. doi:
10.1139/cjm-2020-0004. [PMID: 32073898] - Maqsood Ahmed, Qin Peiwen, Zumin Gu, Yuyang Liu, Aatika Sikandar, Dilbar Hussain, Ansar Javeed, Jamil Shafi, Mazher Farid Iqbal, Ran An, Hongxia Guo, Ying Du, Weijing Wang, Yumeng Zhang, Mingshan Ji. Insecticidal activity and biochemical composition of Citrullus colocynthis, Cannabis indica and Artemisia argyi extracts against cabbage aphid (Brevicoryne brassicae L.).
Scientific reports.
2020 01; 10(1):522. doi:
10.1038/s41598-019-57092-5. [PMID: 31949220] - Hao Chen, Jingquan Yuan, Ji Hao, Yanzhang Wen, Yibing Lv, Lu Chen, Xinzhou Yang. α-Humulene inhibits hepatocellular carcinoma cell proliferation and induces apoptosis through the inhibition of Akt signaling.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2019 Dec; 134(?):110830. doi:
10.1016/j.fct.2019.110830. [PMID: 31562948] - Antonella Rigo, Isacco Ferrarini, Erika Lorenzetto, Elena Darra, Irene Liparulo, Christian Bergamini, Cinzia Sissa, Elisabetta Cavalieri, Fabrizio Vinante. BID and the α-bisabolol-triggered cell death program: converging on mitochondria and lysosomes.
Cell death & disease.
2019 11; 10(12):889. doi:
10.1038/s41419-019-2126-8. [PMID: 31767857] - Jingru Sun, Guanghong Cui, Xiaohui Ma, Zhilai Zhan, Ying Ma, Zhongqiu Teng, Wei Gao, Yanan Wang, Tong Chen, Changjiangsheng Lai, Yujun Zhao, Jinfu Tang, Huixin Lin, Ye Shen, Wen Zeng, Juan Guo, Luqi Huang. An integrated strategy to identify genes responsible for sesquiterpene biosynthesis in turmeric.
Plant molecular biology.
2019 Oct; 101(3):221-234. doi:
10.1007/s11103-019-00892-0. [PMID: 31203559] - E A J Silva, E B B Estevam, T S Silva, H D Nicolella, R A Furtado, C C F Alves, E L Souchie, C H G Martins, D C Tavares, L C A Barbosa, M L D Miranda. Antibacterial and antiproliferative activities of the fresh leaf essential oil of Psidium guajava L. (Myrtaceae).
Brazilian journal of biology = Revista brasleira de biologia.
2019 Oct; 79(4):697-702. doi:
10.1590/1519-6984.189089. [PMID: 30462815] - Abeer A Mohamed, Said I Behiry, Hosny A Younes, Nader A Ashmawy, Mohamed Z M Salem, Ofelia Márquez-Molina, Alberto Barbabosa-Pilego. Antibacterial activity of three essential oils and some monoterpenes against Ralstonia solanacearum phylotype II isolated from potato.
Microbial pathogenesis.
2019 Oct; 135(?):103604. doi:
10.1016/j.micpath.2019.103604. [PMID: 31247257] - Michaela Šadibolová, Tomáš Zárybnický, Tomáš Smutný, Petr Pávek, Zdeněk Šubrt, Petra Matoušková, Lenka Skálová, Iva Boušová. Sesquiterpenes Are Agonists of the Pregnane X Receptor but Do Not Induce the Expression of Phase I Drug-Metabolizing Enzymes in the Human Liver.
International journal of molecular sciences.
2019 Sep; 20(18):. doi:
10.3390/ijms20184562. [PMID: 31540101] - Alline L B Dias, Hellen R F Batista, Elisângela B B Estevam, Cassia C F Alves, Moacir R Forim, Heloiza D Nicolella, Ricardo A Furtado, Denise C Tavares, Thayna S Silva, Carlos H G Martins, Mayker L D Miranda. Chemical composition and in vitro antibacterial and antiproliferative activities of the essential oil from the leaves of Psidium myrtoides O. Berg (Myrtaceae).
Natural product research.
2019 Sep; 33(17):2566-2570. doi:
10.1080/14786419.2018.1457664. [PMID: 29611435] - Siwar Majdoub, Ridha El Mokni, Aliev Aslan Muradalievich, Alessandra Piras, Silvia Porcedda, Saoussen Hammami. Effect of pressure variation on the efficiency of supercritical fluid extraction of wild carrot (Daucus carota subsp. maritimus) extracts.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2019 Sep; 1125(?):121713. doi:
10.1016/j.jchromb.2019.121713. [PMID: 31323559] - Paskorn Muangphrom, Momoka Misaki, Munenori Suzuki, Masaya Shimomura, Hideyuki Suzuki, Hikaru Seki, Toshiya Muranaka. Identification and characterization of (+)-α-bisabolol and 7-epi-silphiperfol-5-ene synthases from Artemisia abrotanum.
Phytochemistry.
2019 Aug; 164(?):144-153. doi:
10.1016/j.phytochem.2019.05.010. [PMID: 31151061] - Tiago Lima Sampaio, Ramon Róseo Paula Pessoa Bezerra de Menezes, Dânya Bandeira Lima, Rose Anny Costa Silva, Isabella Evelyn Prado de Azevedo, Emanuel Paula Magalhães, Márcia Machado Marinho, Ricardo Pires Dos Santos, Alice Maria Costa Martins. Involvement of NADPH-oxidase enzyme in the nephroprotective effect of (-)-α-bisabolol on HK2 cells exposed to ischemia - Reoxygenation.
European journal of pharmacology.
2019 Jul; 855(?):1-9. doi:
10.1016/j.ejphar.2019.04.044. [PMID: 31047876] - Katyuce Souza Farias, Natália Naomi Kato, Amanda Galdi Boaretto, Juliana Inês Weber, Flávia Roberta Brust, Flávio Macedo Alves, Tiana Tasca, Alexandre José Macedo, Denise Brentan Silva, Carlos Alexandre Carollo. Nectandra as a renewable source for (+)-α-bisabolol, an antibiofilm and anti-Trichomonas vaginalis compound.
Fitoterapia.
2019 Jul; 136(?):104179. doi:
10.1016/j.fitote.2019.104179. [PMID: 31121252] - Margarida Costa, Laura Coello, Ralph Urbatzka, Marta Pérez, Margret Thorsteinsdottir. New Aromatic Bisabolane Derivatives with Lipid-Reducing Activity from the Marine Sponge Myrmekioderma sp.
Marine drugs.
2019 Jun; 17(6):. doi:
10.3390/md17060375. [PMID: 31234542] - Airin Ghaderi, Ali Sonboli. Chemical composition and antimicrobial activity of the essential oil of Tanacetum walteri (Anthemideae-Asteraceae) from Iran.
Natural product research.
2019 Jun; 33(12):1787-1790. doi:
10.1080/14786419.2018.1434640. [PMID: 29405745] - V F Carvalho, L Dos A Ramos, C A da Silva, L Nebo, D Moraes, F F A da Silva, N C A da Costa, R de O Rodrigues Junior, L F de Souza, R M Rodrigues. In vitro anthelmintic activity of Siparuna guianensis extract and essential oil against Strongyloides venezuelensis.
Journal of helminthology.
2019 Apr; 94(?):e50. doi:
10.1017/s0022149x19000282. [PMID: 30973122] - Gilcy George Kallivalappil, Girija Kuttan. Evaluation of the anti-inflammatory and urotoxicity ameliorative effects of γ-humulene containing active fraction of Emilia sonchifolia (L.) DC.
Inflammopharmacology.
2019 Apr; 27(2):409-420. doi:
10.1007/s10787-017-0423-3. [PMID: 29224178] - Laura Hévila I Leite, Gerlânia O Leite, Bruno Anderson F da Silva, Sacha Aubrey A R Santos, Francisco Ernani A Magalhães, Paula P Menezes, Mairim R Serafini, Claudener S Teixeira, Renan G Brito, Priscila L Santos, José Galberto M da Costa, Adriano A S Araújo, Lucindo J Quintans-Júnior, Irwin R A de Menezes, Henrique Douglas M Coutinho, Adriana Rolim Campos. Molecular mechanism underlying orofacial antinociceptive activity of Vanillosmopsis arborea Baker (Asteraceae) essential oil complexed with β-cyclodextrin.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2019 Mar; 55(?):293-301. doi:
10.1016/j.phymed.2018.09.173. [PMID: 30293859] - Ah-Reum Lee, Moonhyuk Kwon, Min-Kyoung Kang, Jeonghan Kim, Soo-Un Kim, Dae-Kyun Ro. Increased sesqui- and triterpene production by co-expression of HMG-CoA reductase and biotin carboxyl carrier protein in tobacco (Nicotiana benthamiana).
Metabolic engineering.
2019 03; 52(?):20-28. doi:
10.1016/j.ymben.2018.10.008. [PMID: 30389612] - Mohamed Fizur Nagoor Meeran, Farah Laham, Sheikh Azimullah, Saeed Tariq, Shreesh Ojha. α-Bisabolol abrogates isoproterenol-induced myocardial infarction by inhibiting mitochondrial dysfunction and intrinsic pathway of apoptosis in rats.
Molecular and cellular biochemistry.
2019 Mar; 453(1-2):89-102. doi:
10.1007/s11010-018-3434-5. [PMID: 30159796] - Madona Khoury, Marc El Beyrouthy, Naïm Ouaini, Véronique Eparvier, Didier Stien. Hirtellina lobelii DC. essential oil, its constituents, its combination with antimicrobial drugs and its mode of action.
Fitoterapia.
2019 Mar; 133(?):130-136. doi:
10.1016/j.fitote.2019.01.001. [PMID: 30654130] - Hai Ming Zhang, Shan Shan Guo, Bin Fan, Shu Shan Du, Yong Yan Wang, Zhi Wei Deng. Evaluation of efficacy of the essential oil from Ostericum viridiflorum (Turcz.) Kitagawa in control of stored product insects.
Environmental science and pollution research international.
2019 Jan; 26(2):1406-1413. doi:
10.1007/s11356-018-3728-x. [PMID: 30426372] - Nael Abutaha, Fahd A Nasr, Mohammed Al-Zharani, Ali S Alqahtani, Omar M Noman, Mohammed Mubarak, Semlali Abdelhabib, Muhammad A Wadaan. Effects of Hexane Root Extract of Ferula hermonis Boiss. on Human Breast and Colon Cancer Cells: An In Vitro and In Vivo Study.
BioMed research international.
2019; 2019(?):3079895. doi:
10.1155/2019/3079895. [PMID: 31380416] - Sandra Márcia Mazutti da Silva, Claudio Rodrigues Rezende Costa, Guilherme Martins Gelfuso, Eliete Neves Silva Guerra, Yanna Karla de Medeiros Nóbrega, Sueli Maria Gomes, Aline Pic-Taylor, Yris Maria Fonseca-Bazzo, Damaris Silveira, Pérola de Oliveira Magalhães. Wound Healing Effect of Essential Oil Extracted from Eugenia dysenterica DC (Myrtaceae) Leaves.
Molecules (Basel, Switzerland).
2018 Dec; 24(1):. doi:
10.3390/molecules24010002. [PMID: 30577426] - Thierry L Delatte, Giulia Scaiola, Jamil Molenaar, Katyuce de Sousa Farias, Leticia Alves Gomes Albertti, Jacqueline Busscher, Francel Verstappen, Carlos Carollo, Harro Bouwmeester, Jules Beekwilder. Engineering storage capacity for volatile sesquiterpenes in Nicotiana benthamiana leaves.
Plant biotechnology journal.
2018 12; 16(12):1997-2006. doi:
10.1111/pbi.12933. [PMID: 29682901] - Jane M Budel, Mei Wang, Vijayasankar Raman, Jianping Zhao, Shabana I Khan, Junaid U Rehman, Natascha Techen, Babu Tekwani, Luciane M Monteiro, Gustavo Heiden, Inês J M Takeda, Paulo V Farago, Ikhlas A Khan. Essential Oils of Five Baccharis Species: Investigations on the Chemical Composition and Biological Activities.
Molecules (Basel, Switzerland).
2018 Oct; 23(10):. doi:
10.3390/molecules23102620. [PMID: 30322067] - Mohamed Fizur Nagoor Meeran, Farah Laham, Hasan Al-Taee, Sheikh Azimullah, Shreesh Ojha. Protective effects of α-bisabolol on altered hemodynamics, lipid peroxidation, and nonenzymatic antioxidants in isoproterenol-induced myocardial infarction: In vivo and in vitro evidences.
Journal of biochemical and molecular toxicology.
2018 Oct; 32(10):e22200. doi:
10.1002/jbt.22200. [PMID: 30088836] - Mehdi Sharifi-Rad, Jolanta Nazaruk, Letizia Polito, Maria Flaviana Bezerra Morais-Braga, Janaína Esmeraldo Rocha, Henrique Douglas Melo Coutinho, Bahare Salehi, Giulia Tabanelli, Chiara Montanari, María Del Mar Contreras, Zubaida Yousaf, William N Setzer, Deepa R Verma, Miquel Martorell, Antoni Sureda, Javad Sharifi-Rad. Matricaria genus as a source of antimicrobial agents: From farm to pharmacy and food applications.
Microbiological research.
2018 Oct; 215(?):76-88. doi:
10.1016/j.micres.2018.06.010. [PMID: 30172312] - Soumaya Hajaji, Ines Sifaoui, Atteneri López-Arencibia, María Reyes-Batlle, Ignacio A Jiménez, Isabel L Bazzocchi, Basilio Valladares, Hafidh Akkari, Jacob Lorenzo-Morales, José E Piñero. Leishmanicidal activity of α-bisabolol from Tunisian chamomile essential oil.
Parasitology research.
2018 Sep; 117(9):2855-2867. doi:
10.1007/s00436-018-5975-7. [PMID: 29955971] - Ekaterina Jeliazkova, Valtcho D Zheljazkov, Miroslava Kačániova, Tess Astatkie, Babu L Tekwani. Sequential Elution of Essential Oil Constituents during Steam Distillation of Hops (Humulus lupulus L.) and Influence on Oil Yield and Antimicrobial Activity.
Journal of oleo science.
2018 Jul; 67(7):871-883. doi:
10.5650/jos.ess17216. [PMID: 29877222] - Mina Yarazavi, Ebrahim Noroozian. A novel sorbent based on carbon nanotube/amino-functionalized sol-gel for the headspace solid-phase microextraction of α-bisabolol from medicinal plant samples using experimental design.
Journal of separation science.
2018 May; 41(10):2229-2236. doi:
10.1002/jssc.201700993. [PMID: 29436123] - Raju Sripathi, Dharani Jayagopal, Subban Ravi. A study on the seasonal variation of the essential oil composition from Plectranthus hadiensis and its antibacterial activity.
Natural product research.
2018 Apr; 32(7):871-874. doi:
10.1080/14786419.2017.1363748. [PMID: 28783957] - Giovanni Benelli, Mohan Rajeswary, Marimuthu Govindarajan. Towards green oviposition deterrents? Effectiveness of Syzygium lanceolatum (Myrtaceae) essential oil against six mosquito vectors and impact on four aquatic biological control agents.
Environmental science and pollution research international.
2018 Apr; 25(11):10218-10227. doi:
10.1007/s11356-016-8146-3. [PMID: 27921244] - Thomas Krieg, Anne Sydow, Sonja Faust, Ina Huth, Dirk Holtmann. CO2 to Terpenes: Autotrophic and Electroautotrophic α-Humulene Production with Cupriavidus necator.
Angewandte Chemie (International ed. in English).
2018 02; 57(7):1879-1882. doi:
10.1002/anie.201711302. [PMID: 29232490] - Giovanni Benelli, Marimuthu Govindarajan, Mohan Rajeswary, Baskaralingam Vaseeharan, Sami A Alyahya, Naiyf S Alharbi, Shine Kadaikunnan, Jamal M Khaled, Filippo Maggi. Insecticidal activity of camphene, zerumbone and α-humulene from Cheilocostus speciosus rhizome essential oil against the Old-World bollworm, Helicoverpa armigera.
Ecotoxicology and environmental safety.
2018 Feb; 148(?):781-786. doi:
10.1016/j.ecoenv.2017.11.044. [PMID: 29190597] - Zhehao Jin, Moonhyuk Kwon, Ah-Reum Lee, Dae-Kyun Ro, Juraithip Wungsintaweekul, Soo-Un Kim. Molecular cloning and functional characterization of three terpene synthases from unripe fruit of black pepper (Piper nigrum).
Archives of biochemistry and biophysics.
2018 01; 638(?):35-40. doi:
10.1016/j.abb.2017.12.011. [PMID: 29248443] - Katyuce de S Farias, Thierry Delatte, Rosani do C de O Arruda, Flavio M Alves, Denise B Silva, Jules Beekwilder, Carlos A Carollo. In depth investigation of the metabolism of Nectandra megapotamica chemotypes.
PloS one.
2018; 13(8):e0201996. doi:
10.1371/journal.pone.0201996. [PMID: 30080887] - Linh Thuy Nguyen, Zuzana Myslivečková, Barbora Szotáková, Alena Špičáková, Kateřina Lněničková, Martin Ambrož, Vladimír Kubíček, Kristýna Krasulová, Pavel Anzenbacher, Lenka Skálová. The inhibitory effects of β-caryophyllene, β-caryophyllene oxide and α-humulene on the activities of the main drug-metabolizing enzymes in rat and human liver in vitro.
Chemico-biological interactions.
2017 Dec; 278(?):123-128. doi:
10.1016/j.cbi.2017.10.021. [PMID: 29074051] - Shirlley F M da Luz, Lydia F Yamaguchi, Massuo J Kato, Oriel F de Lemos, Luciana P Xavier, José Guilherme S Maia, Alessandra de R Ramos, William N Setzer, Joyce Kelly do R da Silva. Secondary Metabolic Profiles of Two Cultivars of Piper nigrum (Black Pepper) Resulting from Infection by Fusarium solani f. sp. piperis.
International journal of molecular sciences.
2017 Dec; 18(12):. doi:
10.3390/ijms18122434. [PMID: 29215548] - Lars-Gernot Otto, Prodyut Mondal, Jonathan Brassac, Susanne Preiss, Jörg Degenhardt, Sang He, Jochen Christoph Reif, Timothy Francis Sharbel. Use of genotyping-by-sequencing to determine the genetic structure in the medicinal plant chamomile, and to identify flowering time and alpha-bisabolol associated SNP-loci by genome-wide association mapping.
BMC genomics.
2017 08; 18(1):599. doi:
10.1186/s12864-017-3991-0. [PMID: 28797221] - Chad M Rigsby, Nathaniel B McCartney, Daniel A Herms, James H Tumlinson, Don Cipollini. Variation in the Volatile Profiles of Black and Manchurian Ash in Relation to Emerald Ash Borer Oviposition Preferences.
Journal of chemical ecology.
2017 Aug; 43(8):831-842. doi:
10.1007/s10886-017-0873-5. [PMID: 28752407] - Abolfazl Shakeri, Javad Akhtari, Vahid Soheili, Seyedeh Faezeh Taghizadeh, Amirhossein Sahebkar, Rezvan Shaddel, Javad Asili. Identification and biological activity of the volatile compounds of Glycyrrhiza triphylla Fisch. & C.A.Mey.
Microbial pathogenesis.
2017 Aug; 109(?):39-44. doi:
10.1016/j.micpath.2017.05.022. [PMID: 28526637] - Laura Scalvenzi, Alessandro Grandini, Antonella Spagnoletti, Massimo Tacchini, David Neill, José Luis Ballesteros, Gianni Sacchetti, Alessandra Guerrini. Myrcia splendens (Sw.) DC. (syn. M. fallax (Rich.) DC.) (Myrtaceae) Essential Oil from Amazonian Ecuador: A Chemical Characterization and Bioactivity Profile.
Molecules (Basel, Switzerland).
2017 Jul; 22(7):. doi:
10.3390/molecules22071163. [PMID: 28704964] - Soumaya Hajaji, Ines Sifaoui, Atteneri López-Arencibia, María Reyes-Batlle, Basilio Valladares, José E Pinero, Jacob Lorenzo-Morales, Hafidh Akkari. Amoebicidal activity of α-bisabolol, the main sesquiterpene in chamomile (Matricaria recutita L.) essential oil against the trophozoite stage of Acanthamoeba castellani Neff.
Acta parasitologica.
2017 Jun; 62(2):290-295. doi:
10.1515/ap-2017-0036. [PMID: 28426414] - Franciane Brackmann Mendes, Letícia Scussel Bergamin, Cristiane Dos Santos Stuepp, Elizandra Braganhol, Thatiana Terroso, Adriana Rafin Pohlmann, Sílvia Stanisçuaski Guterres, Ana Maria Oliveira Battastini. Alpha-bisabolol Promotes Glioma Cell Death by Modulating the Adenosinergic System.
Anticancer research.
2017 04; 37(4):1819-1823. doi:
10.21873/anticanres.11516. [PMID: 28373446] - Salvatore Chirumbolo, Geir Bjørklund. The sesquiterpene α-bisabolol in the adipocyte-cancer desmoplastic crosstalk: does it have an action on epithelial-mesenchymal transition mechanisms?.
International journal of clinical oncology.
2017 Apr; 22(2):222-228. doi:
10.1007/s10147-016-1072-z. [PMID: 27942879] - Mashael Marzouq AlShebly, Fatma Saeed AlQahtani, Marimuthu Govindarajan, Kasi Gopinath, Periasamy Vijayan, Giovanni Benelli. Toxicity of ar-curcumene and epi-β-bisabolol from Hedychium larsenii (Zingiberaceae) essential oil on malaria, chikungunya and St. Louis encephalitis mosquito vectors.
Ecotoxicology and environmental safety.
2017 Mar; 137(?):149-157. doi:
10.1016/j.ecoenv.2016.11.028. [PMID: 27918946] - Manel Boumaraf, Marianna Carbone, M Letizia Ciavatta, Samira Benyahia, Souad Ameddah, Ahmed Menad, Samir Benayache, Fadila Benayache, Margherita Gavagnin. Exploring the Bioactive Terpenoid Content of an Algerian Plant of the Genus Pulicaria: The ent-Series of Asteriscunolides.
Journal of natural products.
2017 01; 80(1):82-89. doi:
10.1021/acs.jnatprod.6b00717. [PMID: 28032767] - Tiago J T de Souza, Sérgio A L Bordignon, Miriam A Apel. A Chemometrics Approach to the Investigation of the Intraspecific Variability of the Volatile Oil of Eupatorium tremulum from Southern Brazil.
Journal of natural products.
2017 01; 80(1):45-52. doi:
10.1021/acs.jnatprod.6b00313. [PMID: 28098995]