(S)-bupropion (BioDeep_00000844890)
代谢物信息卡片
化学式: C13H18ClNO (239.1076848)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(C(=O)C1=CC(=CC=C1)Cl)NC(C)(C)C
InChI: InChI=1S/C13H18ClNO/c1-9(15-13(2,3)4)12(16)10-6-5-7-11(14)8-10/h5-9,15H,1-4H3/t9-/m0/s1
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Peter H Silverstone, Robert Williams, Louis McMahon, Rosanna Fleming, Siobhan Fogarty. Convulsive liability of bupropion hydrochloride metabolites in Swiss albino mice.
Annals of general psychiatry.
2008 Oct; 7(?):19. doi:
10.1186/1744-859x-7-19. [PMID: 18922171] - Evan D Kharasch, Darain Mitchell, Rebecka Coles, Roberto Blanco. Rapid clinical induction of hepatic cytochrome P4502B6 activity by ritonavir.
Antimicrobial agents and chemotherapy.
2008 May; 52(5):1663-9. doi:
10.1128/aac.01600-07. [PMID: 18285471] - Evan D Kharasch, Darain Mitchell, Rebecka Coles. Stereoselective bupropion hydroxylation as an in vivo phenotypic probe for cytochrome P4502B6 (CYP2B6) activity.
Journal of clinical pharmacology.
2008 Apr; 48(4):464-74. doi:
10.1177/0091270008314254. [PMID: 18287571] - Scott Wilkes. The use of bupropion SR in cigarette smoking cessation.
International journal of chronic obstructive pulmonary disease.
2008; 3(1):45-53. doi:
10.2147/copd.s1121. [PMID: 18488428] - Rebecka Coles, Evan D Kharasch. Stereoselective analysis of bupropion and hydroxybupropion in human plasma and urine by LC/MS/MS.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2007 Sep; 857(1):67-75. doi:
10.1016/j.jchromb.2007.07.007. [PMID: 17656162] - Miia Turpeinen, Ari Tolonen, Jouko Uusitalo, Jorma Jalonen, Olavi Pelkonen, Kari Laine. Effect of clopidogrel and ticlopidine on cytochrome P450 2B6 activity as measured by bupropion hydroxylation.
Clinical pharmacology and therapeutics.
2005 Jun; 77(6):553-9. doi:
10.1016/j.clpt.2005.02.010. [PMID: 15961986] - ". Hidden amphetamines: from smoking cessation to diabetes.
Prescrire international.
2004 Feb; 13(69):18-20. doi:
". [PMID: 15055218] - Sanna Palovaara, Olavi Pelkonen, Jouko Uusitalo, Stefan Lundgren, Kari Laine. Inhibition of cytochrome P450 2B6 activity by hormone replacement therapy and oral contraceptive as measured by bupropion hydroxylation.
Clinical pharmacology and therapeutics.
2003 Oct; 74(4):326-33. doi:
10.1016/s0009-9236(03)00202-9. [PMID: 14534519] - H D Desai, J Seabolt, M W Jann. Smoking in patients receiving psychotropic medications: a pharmacokinetic perspective.
CNS drugs.
2001; 15(6):469-94. doi:
10.2165/00023210-200115060-00005. [PMID: 11524025]