thunberginol F (BioDeep_00000844822)

   

natural product


代谢物信息卡片


thunberginol F

化学式: C15H10O5 (270.0528)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC2=C(C(=C1)O)C(=O)OC2=CC3=CC(=C(C=C3)O)O
InChI: InChI=1S/C15H10O5/c16-10-5-4-8(6-12(10)18)7-13-9-2-1-3-11(17)14(9)15(19)20-13/h1-7,16-18H/b13-7-

描述信息

An isobenzofuranone that is 2-benzofuran-1(3H)-one substituted by a hydroxy group at position 7 and a 3,4-dihydroxybenzylidene group at position 3. It has been isolated from the roots of Scorzonera judaica.

同义名列表

1 个代谢物同义名

thunberginol F



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

17 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Hailong Zhang, Hisashi Matsuda, Akira Kumahara, Yuki Ito, Seikou Nakamura, Masayuki Yoshikawa. New type of anti-diabetic compounds from the processed leaves of Hydrangea macrophylla var. thunbergii (Hydrangeae Dulcis Folium). Bioorganic & medicinal chemistry letters. 2007 Sep; 17(17):4972-6. doi: 10.1016/j.bmcl.2007.06.027. [PMID: 17609121]
  • Qilong Wang, Hisashi Matsuda, Koudai Matsuhira, Seikou Nakamura, Dan Yuan, Masayuki Yoshikawa. Inhibitory effects of thunberginols A, B, and F on degranulations and releases of TNF-alpha and IL-4 in RBL-2H3 cells. Biological & pharmaceutical bulletin. 2007 Feb; 30(2):388-92. doi: 10.1248/bpb.30.388. [PMID: 17268088]
  • H Matsuda, H Shimoda, M Yoshikawa. Structure-requirements of isocoumarins, phthalides, and stilbenes from Hydrangeae Dulcis Folium for inhibitory activity on histamine release from rat peritoneal mast cells. Bioorganic & medicinal chemistry. 1999 Jul; 7(7):1445-50. doi: 10.1016/s0968-0896(99)00058-9. [PMID: 10465418]
  • H Matsuda, H Shimoda, J Yamahara, M Yoshikawa. Immunomodulatory activity of thunberginol A and related compounds isolated from Hydrangeae Dulcis Folium on splenocyte proliferation activated by mitogens. Bioorganic & medicinal chemistry letters. 1998 Feb; 8(3):215-20. doi: 10.1016/s0960-894x(97)10221-9. [PMID: 9871657]
  • M Yoshikawa, E Harada, Y Naitoh, K Inoue, H Matsuda, H Shimoda, J Yamahara, N Murakami. Development of bioactive functions in hydrangeae dulcis folium. III. On the antiallergic and antimicrobial principles of hydrangeae dulcis folium. (1). Thunberginols A, B, and F. Chemical & pharmaceutical bulletin. 1994 Nov; 42(11):2225-30. doi: 10.1248/cpb.42.2225. [PMID: 7532114]
  • M Yoshikawa, E Uchida, N Chatani, N Murakami, J Yamahara. Thunberginols A, B, and F, new antiallergic and antimicrobial principles from hydrangeae dulcis folium. Chemical & pharmaceutical bulletin. 1992 Nov; 40(11):3121-3. doi: 10.1248/cpb.40.3121. [PMID: 1477932]